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https://www.readbyqxmd.com/read/29738472/smart-waste-collection-system-with-low-consumption-lorawan-nodes-and-route-optimization
#1
Álvaro Lozano, Javier Caridad, Juan Francisco De Paz, Gabriel Villarrubia González, Javier Bajo
New solutions for managing waste have emerged due to the rise of Smart Cities and the Internet of Things. These solutions can also be applied in rural environments, but they require the deployment of a low cost and low consumption sensor network which can be used by different applications. Wireless technologies such as LoRa and low consumption microcontrollers, such as the SAM L21 family make the implementation and deployment of this kind of sensor network possible. This paper introduces a waste monitoring and management platform used in rural environments...
May 8, 2018: Sensors
https://www.readbyqxmd.com/read/29702039/communication-and-healthcare-self-reports-of-people-with-hearing-loss-in-primary-care-settings
#2
Madelyn N Stevens, Judy R Dubno, Margaret I Wallhagen, Debara L Tucci
OBJECTIVES: To assess the experiences of people with hearing loss in healthcare environments to characterize miscommunication and unmet needs, and guide recommendations for improving outcomes and access. METHODS: Anonymous survey developed by subject-matter experts was posted on a large national hearing-loss consumer and advocacy organization website and email listserv. Data were collected and managed via RedCAP. RESULTS: Responses were received from 1581 individuals...
March 20, 2018: Clinical Gerontologist
https://www.readbyqxmd.com/read/29657859/a-survey-of-practices-for-the-use-of-electronic-health-records-to-support-research-recruitment
#3
Jihad S Obeid, Laura M Beskow, Marie Rape, Ramkiran Gouripeddi, R Anthony Black, James J Cimino, Peter J Embi, Chunhua Weng, Rebecca Marnocha, John B Buse
Electronic health records (EHRs) provide great promise for identifying cohorts and enhancing research recruitment. Such approaches are sorely needed, but there are few descriptions in the literature of prevailing practices to guide their use. A multidisciplinary workgroup was formed to examine current practices in the use of EHRs in recruitment and to propose future directions. The group surveyed consortium members regarding current practices. Over 98% of the Clinical and Translational Science Award Consortium responded to the survey...
August 2017: Journal of Clinical and Translational Science
https://www.readbyqxmd.com/read/29593987/luteal-phase-support-for-documented-failure-of-placental-steroidogenesis-a-case-report
#4
Bryan Kratz, Amer Rasheed, John P Holden
Objective: To report a case of a habitual aborter that had a pregnancy reach near term and successfully delivered a viable female infant. Design: Report of a unique case of a G10P1 that was successfully able to maintain a pregnancy by maintaining serum levels of estradiol and progesterone at or above 200 pg/dL and 25 ng/dL respectively. This case provides a benchmark for exogenous support of estradiol and progesterone throughout pregnancy. Setting: A private advanced reproductive center...
April 2017: Case Reports in Women's Health
https://www.readbyqxmd.com/read/29570554/paediatric-intestinal-pseudo-obstruction-evidence-and-consensus-based-recommendations-from-an-espghan-led-expert-group
#5
Nikhil Thapar, Efstratios Saliakellis, Marc A Benninga, Osvaldo Borrelli, Joe Curry, Christophe Faure, Roberto De Giorgio, Girish Gupte, Charles H Knowles, Annamaria Staiano, Yvan Vandenplas, Carlo Di Lorenzo
OBJECTIVES: Chronic intestinal pseudo-obstructive (CIPO) conditions are considered the most severe disorders of gut motility. They continue to present significant challenges in clinical care despite considerable recent progress in our understanding of pathophysiology, resulting in unacceptable levels of morbidity and mortality. Major contributors to the disappointing lack of progress in paediatric CIPO include a dearth of clarity and uniformity across all aspects of clinical care from definition and diagnosis to management...
March 22, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29536258/a-guide-to-missing-data-for-the-pediatric-nephrologist
#6
Nicholas G Larkins, Jonathan C Craig, Armando Teixeira-Pinto
Missing data is an important and common source of bias in clinical research. Readers should be alert to and consider the impact of missing data when reading studies. Beyond preventing missing data in the first place, through good study design and conduct, there are different strategies available to handle data containing missing observations. Complete case analysis is often biased unless data are missing completely at random. Better methods of handling missing data include multiple imputation and models using likelihood-based estimation...
March 13, 2018: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/29527466/identifying-quality-improvement-targets-to-facilitate-colorectal-cancer-screening-completion
#7
Simon J Craddock Lee, Stephen J Inrig, Bijal A Balasubramanian, Celette Sugg Skinner, Robin T Higashi, Katharine McCallister, Wendy Pechero Bishop, Noel O Santini, Jasmin A Tiro
The colorectal cancer (CRC) screening process involves multiple interfaces (communication exchanges and transfers of responsibility for specific actions) among primary care and gastroenterology providers, laboratory, and administrative staff. After a retrospective electronic health record (EHR) analysis discovered substantial clinic variation and low CRC screening prevalence overall in an urban, integrated safety-net system, we launched a qualitative analysis to identify potential quality improvement targets to enhance fecal immunochemical test (FIT) completion, the system's preferred screening modality...
March 2018: Preventive Medicine Reports
https://www.readbyqxmd.com/read/29526789/lateral-habenular-norepinephrine-contributes-to-states-of-arousal-and-anxiety-in-male-rats
#8
Erin M Purvis, Adam K Klein, Aaron Ettenberg
Recent research has identified the lateral habenula (LHb) as a brain region playing an important role in the production of stressful and anxiogenic states. Additionally, norepinephrine (NE) has long been known to be involved in arousal, stress and anxiety, and NE projections to the LHb have been identified emanating from the locus coeruleus (LC). The current research was devised to test the hypothesis that NE release within the LHb contributes to the occurrence of anxiogenic behaviors. Male rats were implanted with bilateral guide cannula aimed at the LHb and subsequently treated with intracranial (IC) infusions of the selective α2 adrenergic autoreceptor agonist, dexmedetomidine (DEX) (0, 0...
March 9, 2018: Behavioural Brain Research
https://www.readbyqxmd.com/read/29519411/feasibility-of-setting-up-generic-alert-levels-for-maximum-skin-dose-in-fluoroscopically-guided-procedures
#9
Hannu Jarvinen, Jad Farah, Teemu Siiskonen, Olivera Ciraj-Bjelac, Jérémie Dabin, Eleftheria Carinou, Joanna Domienik-Andrzejewska, Dariusz Kluszczynski, Željka Knežević, Renata Kopec, Marija Majer, Francoise Malchair, Anna Negri, Piotr Pankowski, Sandra Sarmento, Annalisa Trianni
PURPOSE: The feasibility of setting-up generic, hospital-independent dose alert levels to initiate vigilance on possible skin injuries in interventional procedures was studied for three high-dose procedures (chemoembolization (TACE) of the liver, neuro-embolization (NE) and percutaneous coronary intervention (PCI)) in 9 European countries. METHODS: Gafchromic® films and thermoluminescent dosimeters (TLD) were used to determine the Maximum Skin Dose (MSD). Correlation of the online dose indicators (fluoroscopy time, kerma- or dose-area product (KAP or DAP) and cumulative air kerma at interventional reference point (Ka,r )) with MSD was evaluated and used to establish the alert levels corresponding to a MSD of 2 Gy and 5 Gy...
February 2018: Physica Medica: PM
https://www.readbyqxmd.com/read/29503421/-the-pharmaceuticals-and-medical-devices-agency-s-approach-to-facilitate-risk-communication-and-its-challenges
#10
REVIEW
Emiko Kondo, Mayumi Torii, Izumi Oba, Mai Okamoto
 The issue of drug lag in Japan has been rapidly reduced in recent years, and newly approved drugs now become available on Japanese and international markets at the same time. In this context, the risk management plan (RMP) system was introduced in 2012. RMPs describe important safety concerns recognized by Japan's Pharmaceuticals and Medical Devices Agency (PMDA) and marketing authorization holders (MAHs), as well as safety measures that MAHs request healthcare professionals (HCPs) to follow. The publication of RMPs is expected to support the sharing of drug risk management among HCPs during the postmarketing phase...
2018: Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan
https://www.readbyqxmd.com/read/29500157/crush-the-crave-development-and-formative-evaluation-of-a-smartphone-app-for-smoking-cessation
#11
Neill B Baskerville, Laura L Struik, Darly Dash
BACKGROUND: Emerging evidence supports the use of smartphone apps for smoking cessation, especially in young adults given their high smoking rates and high smartphone ownership rates. Although evaluative evidence is encouraging for supporting smoking cessation, there remains a paucity of research describing the design and development processes of mobile health (mHealth) interventions. OBJECTIVE: The aim of this paper was to describe the process of developing Crush the Crave (CTC), an evidence-informed app to support smoking cessation in young adults, and the results of a formative evaluation of app usage behavior, as part of a broader program of research that seeks to establish the effectiveness of the CTC app...
March 2, 2018: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/29493375/tdm-in-psychiatry-and-neurology-a-comprehensive-summary-of-the-consensus-guidelines-for-therapeutic-drug-monitoring-in-neuropsychopharmacology-update-2017-a-tool-for-clinicians-sup
#12
Georgios Schoretsanitis, Michael Paulzen, Stefan Unterecker, Markus Schwarz, Andreas Conca, Gerald Zernig, Gerhard Gründer, Ekkerhard Haen, Pierre Baumann, Niels Bergemann, Hans Willi Clement, Katharina Domschke, Gabriel Eckermann, Karin Egberts, Manfred Gerlach, Christine Greiner, Ursula Havemann-Reinecke, Gudrun Hefner, Renate Helmer, Ger Janssen, Eveline Jaquenoud-Sirot, Gerd Laux, Thomas Messer, Rainald Mössner, Matthias J Müller, Bruno Pfuhlmann, Peter Riederer, Alois Saria, Bernd Schoppek, Margarete Silva Gracia, Benedikt Stegmann, Werner Steimer, Julia C Stingl, Manfred Uhr, Sven Ulrich, Roland Waschgler, Gabriela Zurek, Christoph Hiemke
OBJECTIVES: Therapeutic drug monitoring (TDM) combines the quantification of drug concentrations in blood, pharmacological interpretation and treatment guidance. TDM introduces a precision medicine tool in times of increasing awareness of the need for personalized treatment. In neurology and psychiatry, TDM can guide pharmacotherapy for patient subgroups such as children, adolescents, pregnant women, elderly patients, patients with intellectual disabilities, patients with substance use disorders, individuals with pharmacokinetic peculiarities and forensic patients...
April 2018: World Journal of Biological Psychiatry
https://www.readbyqxmd.com/read/29468448/current-state-of-fetal-intervention-for-lower-urinary-tract-obstruction
#13
REVIEW
Douglass B Clayton, John W Brock
PURPOSE OF THE REVIEW: In this article, we explore the origins of intervention of fetal lower urinary tract obstruction, and we specifically discuss the background and recent outcomes of vesicoamniotic shunt placement and fetal cystoscopy. The article seeks to provide a comprehensive overview of the field while bringing the reader quickly up to speed on the pertinent literature and the critical data that are available to guide decision-making regarding intervention. RECENT FINDINGS: Appropriate patient selection for fetal intervention remains challenging despite advances in prenatal imaging...
February 22, 2018: Current Urology Reports
https://www.readbyqxmd.com/read/29438560/hiite-hiv-1-incidence-and-infection-time-estimator
#14
Sung Yong Park, Tanzy M T Love, Shivankur Kapoor, Ha Youn Lee, John Hancock
Motivation: Around 2.1 million new HIV-1 infections were reported in 2015, alerting that the HIV-1 epidemic remains a significant global health challenge. Precise incidence assessment strengthens epidemic monitoring efforts and guides strategy optimization for prevention programs. Estimating the onset time of HIV-1 infection can facilitate optimal clinical management and identify key populations largely responsible for epidemic spread and thereby infer HIV-1 transmission chains. Our goal is to develop a genomic assay estimating the incidence and infection time in a single cross-sectional survey setting...
February 9, 2018: Bioinformatics
https://www.readbyqxmd.com/read/29422435/the-catch-to-confidentiality-the-use-of-electronic-health-records-in-adolescent-health-care
#15
Timothy Stablein, Keith J Loud, Christopher DiCapua, Denise L Anthony
PURPOSE: This study aims to understand pediatric health-care providers' expectations and the practices they employ to protect confidentiality in electronic health records (EHRs) and subsequently how EHRs affect the documentation and dissemination of information in the course of health-care delivery to adolescent minors. METHODS: Twenty-six pediatric health-care providers participated in in-depth interviews about their experiences using EHRs to understand a broad spectrum of expectations and practices guiding the documentation and dissemination of information in the EHR...
May 2018: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/29369082/compliance-with-the-2009-royal-college-of-obstetricians-and-gynaecologists-guidelines-for-venous-thromboembolic-disease-prophylaxis-in-pregnancy-and-postpartum-period-in-uruguay
#16
Sofía Grille, Gerardo Vitureira, Rosario Morán, Lucía Retamosa, Valeria Alonso, Luis M Gómez, Federico Quartara, Florencia Feldman, Valentina López, Paola Turcatti, Viviana Castro, Leonardo Sosa, Cecilia Guillermo, Lilián Díaz, Mariana Stevenazzi
: Venous thromboembolism remains as one of the leading causes of maternal death. Prevention of venous thromboembolism in the obstetric population is challenging as recommendations for prophylaxis have low grade of evidence. Risk factors and prophylaxis guidelines have been highlighted by Royal College of Obstetricians and Gynaecologists. In 2014, we developed a written alert following this guidelines to guide thromboprophylaxis. The aim of this study is to assess recommendations compliance. This study was conducted at University-Hospital in Uruguay from January 2014 to December 2016...
January 23, 2018: Blood Coagulation & Fibrinolysis: An International Journal in Haemostasis and Thrombosis
https://www.readbyqxmd.com/read/29362208/youth-codesign-of-a-mobile-phone-app-to-facilitate-self-monitoring-and-management-of-mood-symptoms-in-young-people-with-major-depression-suicidal-ideation-and-self-harm
#17
Sarah Elisabeth Hetrick, Jo Robinson, Eloise Burge, Ryan Blandon, Bianca Mobilio, Simon M Rice, Magenta B Simmons, Mario Alvarez-Jimenez, Simon Goodrich, Christopher G Davey
BACKGROUND: Effective treatment of depression in young people is critical, given its prevalence, impacts, and link to suicide. Clinical practice guidelines point to the need for regular monitoring of depression symptom severity and the emergence of suicidal ideation to track treatment progress and guide intervention delivery. Yet, this is seldom integrated in clinical practice. OBJECTIVE: The objective of this study was to address the gap between guidelines about monitoring and real-world practice by codesigning an app with young people that allows for self-monitoring of mood and communication of this monitoring with a clinician...
January 23, 2018: JMIR Mental Health
https://www.readbyqxmd.com/read/29259215/site-specific-chromosomal-gene-insertion-flp-recombinase-versus-cas9-nuclease
#18
Quang Vinh Phan, Jörg Contzen, Petra Seemann, Manfred Gossen
Site-specific recombination systems like those based on the Flp recombinase proved themselves as efficient tools for cell line engineering. The recent emergence of designer nucleases, especially RNA guided endonucleases like Cas9, has considerably broadened the available toolbox for applications like targeted transgene insertions. Here we established a recombinase-mediated cassette exchange (RMCE) protocol for the fast and effective, drug-free isolation of recombinant cells. Distinct fluorescent protein patterns identified the recombination status of individual cells...
December 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29205262/perceptions-on-the-value-of-bodily-functions-in-multiple-sclerosis
#19
C Heesen, R Haase, S Melzig, J Poettgen, M Berghoff, F Paul, U Zettl, M Marziniak, K Angstwurm, R Kern, T Ziemssen, J P Stellmann
BACKGROUND: In neurological diseases presenting with a plethora of symptoms, the value of bodily functions for a given patient might be a guide for clinical management. Multiple sclerosis (MS) is paradigmatic in this respect, and little is known about the value of different bodily functions of patients and their physicians' perceptions. METHODS: In a multicenter study, 171 patients with relapsing-remitting multiple sclerosis (RRMS), 61% with a clinically active disease within the last 2 years were followed over up to 3 years and yearly patients and their study physician rated on the perceived value of 13 bodily functions via a priority list...
March 2018: Acta Neurologica Scandinavica
https://www.readbyqxmd.com/read/29203458/evaluating-in-car-movements-in-the-design-of-mindful-commute-interventions-exploratory-study
#20
Pablo Enrique Paredes, Nur Al-Huda Hamdan, Dav Clark, Carrie Cai, Wendy Ju, James A Landay
BACKGROUND: The daily commute could be a right moment to teach drivers to use movement or breath towards improving their mental health. Long commutes, the relevance of transitioning from home to work, and vice versa and the privacy of commuting by car make the commute an ideal scenario and time to perform mindful exercises safely. Whereas driving safety is paramount, mindful exercises might help commuters decrease their daily stress while staying alert. Increasing vehicle automation may present new opportunities but also new challenges...
December 4, 2017: Journal of Medical Internet Research
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