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S A R Nouraei, E Mucmur, A Dias, C R Butler, R Nandi, M J Eliott, R Hewitt
OBJECTIVE: To validate the airway-dyspnoea-voice-swallow (ADVS) instrument as a disease-specific patient-reported outcome measure in paediatric laryngotracheal stenosis. DESIGN: Prospective observational study. SETTING: A quaternary referral centre for complex airway disease. PARTICIPANTS: Forty eight patients (30 males) with a means age of 49±49 months who underwent laryngotracheal surgery or microlaryngosocpy and bronchoscopy (MLB) following laryngotracheal surgery...
August 20, 2016: Clinical Otolaryngology
Robert W Thompson, Corey Dawkins, Chandu Vemuri, Michael W Mulholland, Tyler D Hadzinsky, Gregory J Pearl
BACKGROUND: High-performance throwing athletes may be susceptible to the development of neurogenic thoracic outlet syndrome (NTOS). This condition can be career-threatening but the outcomes of treatment for NTOS in elite athletes have not been well characterized. The purpose of this study was to utilize objective performance metrics to evaluate the impact of surgical treatment for NTOS in Major League Baseball (MLB) pitchers. METHODS: Thirteen established MLB pitchers underwent operations for NTOS between July 2001 and July 2014...
August 11, 2016: Annals of Vascular Surgery
Lucas Wymore, Paul Chin, Christopher Geary, Gregory Carolan, Daniel Keefe, Heinz Hoenecke, Jan Fronek
BACKGROUND: Ulnar collateral ligament (UCL) reconstruction (UCLR) has been studied and shown to be a successful procedure for returning overhead athletes to sport. Many studies of Major League Baseball (MLB) players have shown high levels of return to play with successful statistical performance. No study has followed professional advancement of drafted pitchers who underwent UCLR as amateurs when compared with drafted pitchers who did not undergo the procedure before selection in the MLB draft...
August 12, 2016: American Journal of Sports Medicine
Diem-Lan Vu, Samuel Cordey, Francisco Brito, Laurent Kaiser
Astroviruses are small, non-enveloped, single-stranded positive RNA viruses that belong to the Astroviridae family. While classical human astroviruses (HAstV) are a well-recognized cause of acute non-bacterial diarrhea among young children worldwide, novel astroviruses, named HAstV-MLB and HAstV-VA/HMO, have been identified recently in humans by molecular assays. They are phylogenetically more related to animal astroviruses than to classical human astroviruses, thus suggesting cross-species transmission. Serological studies demonstrated a surprisingly high seroprevalence in certain populations and highlighted a high infection rate in the early years of life...
September 2016: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
Sun-Chin Yang, Chia-Chi Wang, Shin-Da Lee, Yu Chung Lee, Kuei-Hui Chan, Yi-Liang Chen, Donovan L Fogt, Chia-Hua Kuo
INTRODUCTION: A recent US Major League Baseball (MLB) rule change requires baseball pitchers to deliver pitches within 12 sec. PURPOSES: To examine the effect of three, between-pitch rest intervals on throwing performance during a simulated 7-inning game and muscle damage during post-game recovery. DESIGN: A randomized counter-balanced study. METHODS: Seven intercollegiate pitchers threw 15 pitches per inning for 7 innings with rest interval trials of 8, 12, and 20 sec between pitches and 5 min between innings...
July 18, 2016: Medicine and Science in Sports and Exercise
Brandon J Erickson, Gregory L Cvetanovich, Bernard R Bach, Charles A Bush-Joseph, Nikhil N Verma, Anthony A Romeo
BACKGROUND: Ulnar collateral ligament reconstruction (UCLR) has become a common procedure among Major League Baseball (MLB) pitchers. It is unclear if a limit on innings pitched after UCLR should be instituted to prevent revision UCLR. HYPOTHESIS: Number of innings pitched and number of pitches thrown after UCLR will not affect whether a pitcher requires a revision UCLR. STUDY DESIGN: Descriptive laboratory study. METHODS: All MLB pitchers between 1974 and 2015 who pitched at least 1 full season after UCLR were included in this study...
September 2016: American Journal of Sports Medicine
Qing Li, Hui Wu, Zhimin Li, Qin Ye
In this study, an engineered strain Escherichia coli MLB (ldhA(-)pflB(-)) was constructed for production of succinate from glycerol. The succinate yield was 0.37mol/mol in anaerobic culture, however, the growth and glycerol consumption rates were very slow, resulting in a low succinate level. Two-stage fermentation was performed in flasks, and the succinate yield reached 0.93mol/mol, but the succinate titer was still low. Hence, overexpression of malate dehydrogenase, malic enzyme, phosphoenolpyruvate (PEP) carboxylase and PEP carboxykinase (PCK) from E...
October 2016: Bioresource Technology
John Prodromo, Nimit Patel, Neil Kumar, Kevin Denehy, Loni Philip Tabb, James Tom
BACKGROUND: Ulnar collateral ligament reconstruction (UCLR) is commonly performed in Major League Baseball (MLB) pitchers, but little is known about the preoperative pitch type and velocity characteristics of pitchers who go on to undergo UCLR. HYPOTHESIS: Pitchers who required UCLR have thrown a greater percentage of fastballs and have greater pitch velocities compared with age-matched controls in the season before injury. STUDY DESIGN: Case-control study; Level of evidence, 3...
June 2016: Orthopaedic Journal of Sports Medicine
Alix M Denoncourt, Valérie E Paquet, Ahmadreza Sedighi, Steve J Charette
Dictyostelium discoideum amoebae produce and secrete multilamellar bodies (MLBs) when fed digestible bacteria. The aim of the present study was to elucidate the proteic content of MLBs. The lipid composition of MLBs is mainly amoebal in origin, suggesting that MLB formation is a protozoa-driven process that could play a significant role in amoebal physiology. We identified four major proteins on purified MLBs using mass spectrometry in order to better understand the molecular mechanisms governing MLB formation and, eventually, to elucidate the true function of MLBs...
2016: PloS One
Brandon J Erickson, Bernard R Bach, Charles A Bush-Joseph, Nikhil N Verma, Anthony A Romeo
The ulnar collateral ligament (UCL) is a vital structure to the overhead athlete, especially the baseball pitcher. For reasons not completely understood, UCL injuries have become increasingly more common in major league baseball (MLB) pitchers over the past 10 years. UCL reconstruction (UCLR) is the current gold standard of treatment for these injuries in MLB pitchers who wish to return to sport (RTS) at a high level and who have failed a course of non-operative treatment. Results following UCLR in MLB pitchers have been encouraging, with multiple RTS rates now cited at greater than 80%...
June 18, 2016: World Journal of Orthopedics
David Whiteside, Douglas N Martini, Adam S Lepley, Ronald F Zernicke, Grant C Goulet
BACKGROUND: Ulnar collateral ligament (UCL) reconstruction surgeries in Major League Baseball (MLB) have increased significantly in recent decades. Although several risk factors have been proposed, a scientific consensus is yet to be reached, providing challenges to those tasked with preventing UCL injuries. PURPOSE: To identify significant predictors of UCL reconstruction in MLB pitchers. STUDY DESIGN: Case control study; Level of evidence, 3...
September 2016: American Journal of Sports Medicine
Maria do Socorro da Silva Valente, Cláudia S Lopes, Maria Pastor-Valero, Paulo Rossi Menezes
OBJECTIVES: Changes in the modern economy have affected the financial sector. Time pressures, excessive work demands, and job stress are frequent concerns among bank employees, which might predispose them to burnout symptoms. The objective of the present study was to investigate the association between burnout symptoms and exposure to psychosocial work conditions in bank employees. METHODS: A cross-sectional study of 1046 bank employees was carried out in Pará and Amapá, northern Brazil...
June 2016: Annals of Occupational Hygiene
Brandon J Erickson, Joshua D Harris, Yale A Fillingham, Gregory L Cvetanovich, Charles A Bush-Joseph, Bernard R Bach, Anthony A Romeo, Nikhil N Verma
PURPOSE: To determine practice patterns of Major League Baseball (MLB) team orthopaedic surgeons in addressing the controversial topics of ulnar collateral ligament (UCL) tears, type II SLAP tears, and partial-thickness rotator cuff tear. METHODS: Seventy-four MLB team orthopaedic surgeons were surveyed via an online survey system. A 14-question survey was used to assess surgeon experience, technique, and graft choice for UCL reconstruction (UCLR), treatment of type II SLAP tears, and other common pathologic conditions...
July 2016: Arthroscopy: the Journal of Arthroscopic & related Surgery
Robert A Keller, Nathan E Marshall, John-Michael Guest, Kelechi R Okoroha, Edward K Jung, Vasilios Moutzouros
BACKGROUND: The number of Major League Baseball (MLB) pitchers requiring ulnar collateral ligament (UCL) reconstructions is increasing. Recent literature has attempted to correlate specific stresses placed on the throwing arm to risk for UCL injury, with limited results. METHODS: Eighty-three MLB pitchers who underwent primary UCL reconstruction were evaluated. Pitching velocity and percent of pitch type thrown (fastball, curve ball, slider, and change-up) were evaluated 2 years before and after surgery...
April 2016: Journal of Shoulder and Elbow Surgery
Diane L Dahm, Frank C Curriero, Christopher L Camp, Robert H Brophy, Tony Leo, Keith Meister, George A Paletta, John A Steubs, Bert R Mandelbaum, Keshia M Pollack
Few studies have explored the frequency and impact of lower extremity injuries, such as those to the knee, among professional baseball players. The purpose of this study was to detail the epidemiology of knee injuries in Major League Baseball (MLB) and Minor League Baseball (MiLB) players during the 2011-2014 seasons. It was hypothesized that knee injuries are a common occurrence in these athletes, and represent a significant source of time away from play. The MLB Health and Injury Tracking System database was searched to identify all patients diagnosed with knee injuries during the 2011-2014 seasons...
March 2016: American Journal of Orthopedics
Struan H Coleman, Stephanie W Mayer, Jared J Tyson, Keshia M Pollack, Frank C Curriero
Injuries of the hip and groin among professional baseball players can result in a significant number of disabled list days. The epidemiology of these injuries has not been delineated. The purpose of this study is to describe the incidence, mechanism, type, and rehabilitation course of hip and groin injuries among Major League Baseball (MLB) and Minor League Baseball (MiLB) players. The MLB injury database for hip and groin injuries from 2011-2014 was analyzed. Occurrence of injuries was assessed based on level of play, field location, activity during which the injury occurred, mechanism of injury, and days missed...
March 2016: American Journal of Orthopedics
Brandon J Erickson, Peter N Chalmers, Charles A Bush-Joseph, Anthony A Romeo
Major League Baseball (MLB) players are at significant risk for both chronic, repetitive overuse injuries as well as acute traumatic injuries. Pitchers have been shown to be at higher risk for sustaining injuries, especially upper extremity injuries, than position players. The past several MLB seasons have seen a dramatic rise in the number of ulnar collateral ligament reconstructions performed in MLB pitchers. Several recent prospective studies have identified risk factors for injuries to both the shoulder and elbow in MLB pitchers...
March 2016: American Journal of Orthopedics
Christopher L Camp, Matthew S Conti, Terrance Sgroi, Frank P Cammisa, Joshua S Dines
In recent years, increased attention has been paid to injuries occurring in Major League Baseball (MLB) players. Although most of the current orthopedic literature regarding baseball injuries pertains to the shoulder and elbow, lumbar spine injuries are another common reason for time out of play. Back and core injuries may represent as many as 12% of all injuries that result in time out of play from MLB. This high rate of injury is likely related to the critical role that the spine plays in every major baseball-related movement...
March 2016: American Journal of Orthopedics
Andrew R McNamara, Scott Ensell, Timothy D Farley
Friction blisters are a common sequela of many athletic activities. Their significance can range from minor annoyance to major performance disruptions. The latter is particularly true in baseball pitchers, who sustain repeated trauma between the baseball seams and the fingers of the pitching hand, predominately at the tips of the index and long fingers. Since 2010, 6 Major League Baseball (MLB) players accounted for 7 stints on the disabled list (DL) due to blisters. These injuries resulted in a total of 151 days spent on the DL...
March 2016: American Journal of Orthopedics
Joshua S Dines, Kristofer Jones, Patrick Maher, David Altchek
Clinical outcomes of surgical management of full-thickness rotator cuff tears in professional baseball players have been uniformly poor. We conducted a study to investigate return-to-play data and functional performance using a novel arthroscopic repair technique. We hypothesized that arthroscopic rotator cuff repair would result in a high rate of return to professional pitching and favorable functional outcomes. We identified 6 consecutive Major League Baseball (MLB) pitchers who underwent surgical repair of full-thickness rotator cuff injuries using the lateralized footprint repair technique...
March 2016: American Journal of Orthopedics
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