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https://www.readbyqxmd.com/read/29770281/intestinal-spirochetosis-in-an-immunocompetent-patient
#1
Patricia Guzman Rojas, Jelena Catania, Jignesh Parikh, Tran C Phung, Glenn Speth
Intestinal spirochetosis (IS) is an infestation defined by the presence of spirochetes on the surface of the colonic mucosa. The implicated organisms can be Brachyspira aalborgi or Brachyspira pilosicoli . We present the case of a 66-year-old man with a past medical history of diabetes mellitus, hypertension, morbid obesity, and gastroesophageal reflux. The patient was sent to the gastroenterology clinic for a screening colonoscopy due to a prior history of colonic polyps. The patient was completely asymptomatic as he denies any abdominal pain, diarrhea, melena, or hematochezia...
March 15, 2018: Curēus
https://www.readbyqxmd.com/read/29761252/testing-and-treating-small-intestinal-bacterial-overgrowth-reduces-symptoms-in-patients-with-inflammatory-bowel-disease
#2
Shirley Cohen-Mekelburg, Zaid Tafesh, Elliot Coburn, Russell Weg, Neena Malik, Colleen Webb, Hoda Hammad, Ellen Scherl, Brian P Bosworth
BACKGROUND: Common mechanisms against small intestinal bacterial overgrowth (SIBO), including an intact ileocecal valve, gastric acid secretion, intestinal motility, and an intact immune system, are compromised in inflammatory bowel disease (IBD), and therefore, a relatively high incidence of SIBO has been reported in this population. AIMS: We aimed to determine whether an improvement in IBD clinical activity scores is seen after testing and treating SIBO. METHODS: A retrospective cohort study of 147 patients with inflammatory bowel disease who were referred for SIBO breath testing from 1/2012 to 5/2016 was performed...
May 14, 2018: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29756103/factors-affecting-successful-colonoscopy-procedures-single-center-experience
#3
Ramazan Kozan, Tonguç Utku Yılmaz, Uygar Baştuğral, Umut Kerimoğlu, Yücel Yavuz
Objective: Colonoscopy is a gold standard procedure for several colon pathologies. Successful colonoscopy means demonstration of the ileocecal valve and determination of colon polyps. Here we aimed to evaluate our colonoscopy success and results. Material and Methods: This retrospective descriptive study was performed in İstanbul Eren hospital endoscopy unit between 2012 and 2015. Colonoscopy results and patient demographics were obtained from the hospital database...
2018: Turkish Journal of Surgery
https://www.readbyqxmd.com/read/29753524/short-bowel-mucosal-morphology-proliferation-and-inflammation-at-first-and-repeat-step-procedures
#4
Annika Mutanen, Meredith Barrett, Yongjia Feng, Jouko Lohi, Raja Rabah, Daniel H Teitelbaum, Mikko P Pakarinen
BACKGROUND: Although serial transverse enteroplasty (STEP) improves function of dilated short bowel, a significant proportion of patients require repeat surgery. To address underlying reasons for unsuccessful STEP, we compared small intestinal mucosal characteristics between initial and repeat STEP procedures in children with short bowel syndrome (SBS). METHODS: Fifteen SBS children, who underwent 13 first and 7 repeat STEP procedures with full thickness small bowel samples at median age 1...
April 17, 2018: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29749362/effects-of-synbiotics-on-ileal-microbiota
#5
Shunichiro Komatsu, Eiji Sakamoto, Takashi Asahara, Koji Nomoto, Masato Nagino
Background & objectives: Despite advancements in molecular-based methods, the composition of the human ileal microbiota and the effects of synbiotics/probiotics on its microbes remain poorly understood. The aim of this study was to determine the composition of the mucus microbiota in the human ileum and to assess the effects of oral administration of synbiotics on the microbiota. Methods: As part of a clinical trial for synbiotics treatment and surgical infection, ileal mucus was sampled when resection of the ileocecal portion was required...
January 2018: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29742985/laparoscopic-redo-ileocolic-resection-for-crohn-s-disease-in-patients-with-previous-multiple-laparotomies
#6
V Celentano, F Sagias, K G Flashman, J Conti, J Khan
PURPOSES: Over 80% of patients with primary ileocolic Crohn's disease have a surgical resection within 10 years of diagnosis, and 40%-50% of them need further surgery within 15 years. Laparoscopic surgery can be challenging due to a thickened mesentery and the potential for fistulas, abscesses, and phlegmons. Aim of this study is to analyze the short-term outcomes of laparoscopic redo ileocolic resections for Crohn's disease in patients with previous multiple laparotomies. METHODS: All patients undergoing laparoscopic surgery for ileocolic Crohn's disease from March 2006 to February 2017 were prospectively evaluated...
May 1, 2018: Scandinavian Journal of Surgery: SJS
https://www.readbyqxmd.com/read/29736773/risk-factors-for-early-postoperative-complications-and-length-of-hospital-stay-in-ileocecal-resection-and-right-hemicolectomy-for-crohn-s-disease-a-single-center-experience
#7
Christian Galata, Christel Weiss, Julia Hardt, Steffen Seyfried, Stefan Post, Peter Kienle, Karoline Horisberger
PURPOSE: To determine risk factors for early postoperative complications and longer hospital stay after ileocecal resection and right hemicolectomy in a single-center cohort of patients with Crohn's disease (CD). METHODS: A retrospective analysis of the prospectively maintained surgical database for patients with CD at our institution was performed. All consecutive patients operated on between January 2010 and December 2016 were included. RESULTS: A total of 305 patients were included...
May 7, 2018: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/29703052/a-newborn-patient-with-both-annular-pancreas-and-meckel-s-diverticulum-a-case-report-of-an-unusual-association
#8
Peng Cai, Zhenwei Zhu, Jianlei Chen, Lulu Chen, Jiang Pan, Wenxian Zhi, Jie Zhu, Bin Wu, Zhicheng Gu, Shungen Huang, Jian Wang
RATIONALE: Annular pancreas (AP) is recognized as a cause of duodenal obstruction in children, while children with Meckel's diverticulum (MD) are usually asymptomatic. Here we present a rare case with both AP and MD, which was identified by abdominal exploration during diamond-shaped duodenoduodenostomy. PATIENT CONCERNS: A "double-bubble" sign was found by ultrasound at 35 week of pregnancy. After 39 weeks of pregnancy, the male patient was transferred to the Department of General Surgery, Children's Hospital of Soochow University because of a suspected duodenal stenosis...
April 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29699586/intussusception-caused-by-an-inverted-colonic-diverticulum-a-case-report
#9
Bei Zhang, Jiping Wang, Xiaoguang Li, Zhuo Wang, Yangjiao Zhang, Hao Yang
BACKGROUND: Intussusception is an unusual disorder among the complications of diverticula in adults. This study aimed to report intussusception due to an inverted colonic diverticulum. Such a large inverted colonic diverticulum has rarely been reported. CASE PRESENTATION: A 62-year-old Chinese woman presented to the First Hospital of Jilin University with abdominal pain, vomiting, and bloody stool. Preoperative computed tomography imaging indicated intussusception...
April 27, 2018: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29688413/sex-related-differences-in-patients-with-inflammatory-bowel-disease-results-of-2-prospective-cohort-studies
#10
Mirjam Severs, Lieke M Spekhorst, Marie-Josée J Mangen, Gerard Dijkstra, Mark Löwenberg, Frank Hoentjen, Andrea E van der Meulen-de Jong, Marieke Pierik, Cyriel Y Ponsioen, Gerd Bouma, Janneke C van der Woude, Mirthe E van der Valk, Marielle J L Romberg-Camps, Cees H M Clemens, Paul van de Meeberg, Nofel Mahmmod, Jeroen Jansen, Bindia Jharap, Rinse K Weersma, Bas Oldenburg, Eleonora A M Festen, Herma H Fidder
Background: The understanding of gender differences in inflammatory bowel disease (IBD) patients is an important step towards tailored treatment for the individual patient. The aim of this study was to compare disease phenotype, clinical manifestations, disease activity, and healthcare utilization between men and women with Crohn's disease (CD) and ulcerative colitis (UC). Methods: Two multicenter observational cohort studies with a prospective design were used to explore the differences between men and women regarding demographic and phenotypic characteristics and healthcare utilization...
April 21, 2018: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/29682364/gastrointestinal-tuberculosis-presenting-as-malnutrition-and-distal-colonic-bowel-obstruction
#11
Raja Chandra Chakinala, Zahava C Farkas, Benjamin Barbash, Khwaja F Haq, Shantanu Solanki, Muhammad Ali Khan, Edward Esses, Taliya Farooq, Brad Dworkin
Gastrointestinal (GI) tuberculosis (TB) is rare and can occur in the context of active pulmonary disease or as a primary infection with no pulmonary symptoms. It typically presents with vague abdominal symptoms, making it difficult to discern from alternative disease processes. Although the ileocecal region is the most commonly affected site, tuberculous enteritis can involve any aspect of the GI tract. To demonstrate the importance of maintaining a high clinical suspicion for the disease, we present a case of GI TB presenting as severe malnutrition and segmental colitis of the left colon...
2018: Case Reports in Gastrointestinal Medicine
https://www.readbyqxmd.com/read/29676706/-a-man-with-abdominal-pain-diarrhoea-and-rectal-bleeding
#12
A J M Oosterwijk, J W van den Berg, C C van Rossem
A 49-year-old man came to the emergency room with abdominal pain, vomiting, diarrhoea and rectal bleeding. Both colonoscopy and CT of the abdomen showed cecocolic intussusception caused by an appendiceal mucocele. An ileocecal resection was performed via a laparoscopic approach and microscopy of the tissue showed a low-grade mucinous neoplasm.
2018: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/29667709/the-outlet-patch-gastric-heterotopia-of-the-colo-rectum-and-anus
#13
Abul Ala Syed Rifat Mannan, Michael Vieth, Armen Khararjian, Binny Khandakar, Dora Lam-Himlin, David Heydt, Feriyl Bhaijee, Henry J Venbrux, Kathleen Byrnes, Lysandra Voltaggio, Norman Barker, Songyang Yuan, Elizabeth Montgomery
AIMS: Gastric heterotopia (GH) has been described throughout the gastrointestinal tract. However, the colorectal region is an extremely rare location for it. We describe the clinicopathologic features of GH of the colon, rectum, and anus. METHODS AND RESULTS: We identified 33 cases in 20 males and 13 females (median age 54 years; range, 4 months to 73 years). Sites included the rectum (N=26), anus (N=4), ileocecal junction (N=1), ascending colon (N=1) and descending colon (N=1)...
April 18, 2018: Histopathology
https://www.readbyqxmd.com/read/29662538/the-accuracy-of-intestinal-ultrasound-compared-with-small-bowel-capsule-endoscopy-in-assessment-of-suspected-crohn-s-disease-in-patients-with-negative-ileocolonoscopy
#14
Dan Carter, Lior H Katz, Eytan Bardan, Eti Salomon, Shulamit Goldstein, Shomron Ben Horin, Uri Kopylov, Rami Eliakim
Background: Small bowel involvement in Crohn's disease (CD) is frequently proximal to the ileocecal valve and inaccessible by conventional ileocolonoscopy (IC). Small bowel capsule endoscopy (SBCE) is among the prime modalities for assessment of small bowel disease in these patients. Intestinal ultrasound (IUS) is an accurate bedside fast and low-cost diagnostic modality utilized in CD for both diagnosis and monitoring. The aim of this study was to examine the accuracy of IUS in patients with suspected CD after a negative IC, and to evaluate the correlation of IUS with SBCE, inflammatory biomarkers and other cross-sectional imaging techniques...
2018: Therapeutic Advances in Gastroenterology
https://www.readbyqxmd.com/read/29650919/-a-case-of-treated-with-laparoscopic-surgery-for-intussusception-up-to-the-splenic-flexion-region-due-to-cecum-cancer
#15
Go Masuda, Takeshi Hori, Nozomi Iimori, Tomohiro Lee, Masashige Tendo, Bunzo Nakata, Tetsuro Ishikawa
A 93-year-old woman was admitted to the hospital because of respiratorydiscomfort. A chest CT scan indicated aspiration pneumonitis and, simultaneously, intussusception was observed in the splenic flexure region. Abdominal enhance CT scan revealed a tumor in the advanced region of intussusception. Laparoscopy-assisted ileocecal resection was performed. Since the intussusception was difficult to reduce laparoscopically, the ileocecum was mobilized and the intussusception was reduced manually. In the resected specimen, a type 1 tumor was observed in the cecum and histopathologic ally diagnosed as cercal cancer...
March 2018: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29650824/-a-case-report-of-appendiceal-cancer-complicated-appendicitis-treated-with-single-incision-laparoscopic-ileocecal-resection
#16
Taiki Kijima, Hideto Hayashi, Hikari Chijimatsu, Yasunori Yoshimoto, Katsuhiko Morita, Kouichiro Sakata, Mihoko Setoguchi
We report a case of appendicitis with an abscess that was treated with single-incision laparoscopic ileocecal resection with D2 lymphadenectomy because of intraoperative suspicion of appendiceal cancer. A 73-year-old woman was admitted to the hospital because of right lower abdominal pain. She was diagnosed with appendicitis with an abscess. Although single-incision laparoscopic appendectomy was planned, appendiceal cancer was suspected from intraoperative findings. Therefore, we performed single-incision laparoscopic ileocecal resection with D2 lymphadenectomy...
April 2018: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29611764/lenalidomide-combined-with-r-gdp-in-a-patient-with-refractory-cd5-positive-diffuse-large-b-cell-lymphoma-a-promising-response-and-review
#17
Yaping Zhang, Xinfeng Wang, Yifei Liu, Chunfeng Sun, Wenyu Shi, Hongming Huang
CD5-positive (CD5+) diffuse large B-cell lymphoma (DLBCL) is associated with poor survival compared with CD5-negative DLBCL. The clinical characteristics of CD5+ DLBCL are different from both CD5-negative DLBCL and other CD5+ B cell lymphomas. There is currently no promising chemotherapy for CD5+ DLBCL. Herein, we report a 49-year-old Asian male with refractory CD5+ DLBCL. He complained of aggravated abdominal pain and weight loss. Computed tomography scan revealed abdominal masses, widespread lymphadenopathy, splenomegaly, and intussusception of the ileocecal junction with bowel wall thickening...
April 3, 2018: Cancer Biology & Therapy
https://www.readbyqxmd.com/read/29610509/ileocecal-anastomosis-type-significantly-influences-long-term-functional-status-quality-of-life-and-healthcare-utilization-in-postoperative-crohn-s-disease-patients-independent-of-inflammation-recurrence
#18
Mahesh Gajendran, Anthony J Bauer, Bettina M Buchholz, Andrew R Watson, Ioannis E Koutroubakis, Jana G Hashash, Claudia Ramos-Rivers, Nilesh Shah, Kenneth K Lee, Ruy J Cruz, Miguel Regueiro, Brian Zuckerbraun, Marc Schwartz, Jason Swoger, Arthur Barrie, Janet Harrison, Douglas J Hartman, Javier Salgado, William M Rivers, Benjamin Click, Alyce M Anderson, Chandraprakash Umapathy, Dmitriy Babichenko, Michael A Dunn, David G Binion
OBJECTIVES: Anastomotic reconstruction following intestinal resection in Crohn's disease (CD) may employ side-to-side anastomosis (STSA; anti-peristaltic orientation) or end-to-end anastomosis (ETEA). Our aim was to determine the impact of these two anastomotic techniques on long-term clinical status in postoperative CD patients. METHODS: We performed a comparative effectiveness study of prospectively collected observational data from consented CD patients undergoing their first or second ileocolonic bowel resection and re-anastomosis between 2008 and 2012, in order to assess the association between anastomosis type and 2-year postoperative quality of life (QoL), healthcare utilization, disease clinical or endoscopic recurrence, use of medications, and need for repeat resection...
April 2018: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29603368/oral-budesonide-in-gastrointestinal-and-liver-disease-a-practical-guide-for-the-clinician
#19
REVIEW
Stephan Miehlke, Manuel Barreiro-de Acosta, Gerd Bouma, Daniel Carpio, Fernando Magro, Tom Moreels, Chris Probert
Oral budesonide is a second- generation steroid which allows local, selective treatment of the gastrointestinal tract and the liver, minimizing systemic exposure. The results of randomized trials comparing budesonide versus placebo or active comparators have led to expert recommendations that budesonide be used to treat mild or moderate active ileocecal Crohn's disease, microscopic colitis (including both collagenous and lymphocytic colitis), ulcerative colitis and non-cirrhotic autoimmune hepatitis. The mechanism of budesonide action obviates the need for dose tapering due to safety reasons after induction therapy...
March 30, 2018: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29593186/peritoneal-cecal-cancer-metastasis-to-a-mesh-plug-prosthesis-a-case-report
#20
Itaru Shigeyoshi, Koji Komori, Takashi Kinoshita, Taihei Oshiro, Seiji Ito, Tetsuya Abe, Yoshiki Senda, Kazunari Misawa, Yuichi Ito, Norihisa Uemura, Seiji Natsume, Eiji Higaki, Byonggu An, Akira Ouchi, Masayuki Tsutsuyama, Takahiro Hosoi, Daisuke Hayashi, Hideharu Tanaka, Tairin Uchino, Aina Kunitomo, Yasuhiro Shimizu
We report the case of a 77-year-old man who presented to our hospital with cecal cancer, lung metastasis, and liver metastasis in January 2013. After four courses of modified infusional intravenous fluorouracil and levofolinate with oxaliplatin (mFOLFOX 6) + bevacizumab, there was no new metastatic lesion and lung metastasis reduction was observed. Ileocecal resection was performed in May, left lower lung lobectomy in August, and extended right posterior segmentectomy + S8 partial liver resection was performed in December...
2018: Journal of Medical Investigation: JMI
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