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cancellous bone

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https://www.readbyqxmd.com/read/28214401/association-between-loss-of-bone-mass-due-to-short-sleep-and-leptin-sympathetic-nervous-system-activity
#1
Nagato Kuriyama, Masaaki Inaba, Etsuko Ozaki, Yutaro Yoneda, Daisuke Matsui, Kanae Hashiguchi, Teruhide Koyama, Komei Iwai, Isao Watanabe, Rika Tanaka, Chie Omichi, Shigeto Mizuno, Masao Kurokawa, Motoyuki Horii, Fumitoshi Niwa, Koichi Iwasa, Shinsuke Yamada, Yoshiyuki Watanabe
BACKGROUND: Sleep has been reported to be an important factor in bone metabolism, and sympathetic nervous system activity has been reported to regulate bone metabolism. In this study, we evaluated the association between sleep, sympathetic nervous system activity, and bone mass. METHODS: The study subjects were 221 individuals (108 males; 113 females; mean age: 55.1±7.0years) divided into two groups: those who slept for less than 6h a day (short sleep [SS] group), and those who slept 6h or longer (normal sleep [NS] group)...
February 10, 2017: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/28214296/abnormally-high-and-heterogeneous-bone-matrix-mineralization-after-childhood-solid-organ-transplantation-a-complex-pathology-of-low-bone-turnover-and-local-defects-in-mineralization
#2
Nadja Fratzl-Zelman, Helena Valta, Renata C Pereira, Barbara M Misof, Paul Roschger, Hannu Jalanko, Kathrine Wesseling-Perry, Klaus Klaushofer, Outi Mäkitie
Chronic renal, liver and heart failure in children associates with multiple skeletal complications. Increased fracture incidence often persists after transplantation and could be related to alterations in bone material properties. In the present cohort study we evaluated bone mineralization density distribution (BMDD) by quantitative backscattered electron imaging (qBEI) in 23 pediatric solid organ allograft recipients with suspected osteoporosis. We measured BMDD in the entire cross-sectional area of transiliac bone biopsies obtained from kidney (n = 9), liver (n = 9) and heart (n = 5) transplant recipients (aged 7...
February 18, 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/28212452/bone-to-implant-contact-and-new-bone-formation-within-human-freeze-dried-bone-blocks-grafted-over-rabbit-calvaria
#3
Zvi Artzi, Karen Anavi-Lev, Avital Kozlovsky, Liat Chaushu, Frank Schwarz, Haim Tal
PURPOSE: To assess the extent of osseointegration with rough-surface implants and new bone formation (NBF) within human freeze-dried bone blocks (h-FDB) grafted over rabbit calvaria. MATERIALS AND METHODS: A total of 18 rectangular h-FDB blocks were stabilized bilaterally to the calvaria of nine New Zealand rabbits by two mini titanium screws each. A total of 18 rough-surface implants (5.0 × 6.0-mm) were placed, 9 simultaneously (immediate placement [IP]) on one side and 9 at 3 months after block grafting (delayed placement [DP]) on the contralateral side...
February 17, 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/28208578/role-of-cortico-cancellous-heterologous-bone-in-human-periodontal-ligament-stem-cell-xeno-free-culture-studied-by-synchrotron-radiation-phase-contrast-microtomography
#4
Serena Mazzoni, Sara Mohammadi, Giuliana Tromba, Francesca Diomede, Adriano Piattelli, Oriana Trubiani, Alessandra Giuliani
This study was designed to quantitatively demonstrate via three-dimensional (3D) images, through the Synchrotron Radiation Phase-Contrast Microtomography (SR-PhC-MicroCT), the osteoinductive properties of a cortico-cancellous scaffold (Osteobiol Dual Block-DB) cultured with human Periodontal Ligament Stem Cells (hPDLSCs) in xeno-free media. In vitro cultures of hPDLSCs, obtained from alveolar crest and horizontal fibers of the periodontal ligament, were seeded onto DB scaffolds and cultured in xeno-free media for three weeks...
February 10, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28207735/long-non-coding-rna-hotair-inhibits-mir-17-5p-to-regulate-osteogenic-differentiation-and-proliferation-in-non-traumatic-osteonecrosis-of-femoral-head
#5
Biaofang Wei, Wei Wei, Baoxiang Zhao, Xiaxia Guo, Song Liu
BACKGROUND AND AIM: The biological functions of non-coding RNAs (ncRNAs) have been widely identified in many human diseases. In the present study, the relationship between long non-coding RNA HOTAIR and microRNA-17-5p (miR-17-5p) and their roles in osteogenic differentiation and proliferation in non-traumatic osteonecrosis of femoral head (ONFH) were investigated. METHODS: The expression levels of HOTAIR and miR-17-5p in the mesenchymal stem cells (MSCs) derived from patients with non-traumatic ONFH and osteoarthritis (OA) were examined by real-time PCR...
2017: PloS One
https://www.readbyqxmd.com/read/28207619/iliac-crest-regeneration-a-retrospective-study-of-14-years-of-follow-up
#6
Anastasios Christodoulou, Achilleas Boutsiadis, Evangellos Christodoulou, Petros Antonarakos, Panagiotis Givissis, Ippokratis Hatzokos
STUDY DESIGN: This is a retrospective study analysis. OBJECTIVE: The purpose of our study was to evaluate the healing process of the ilium after being used as a bone graft donor site in the treatment of adolescent idiopathic scoliosis. SUMMARY OF BACKGROUND DATA: Iliac crest bone grafts have been proven to be the most reliable means for solid fusion in spine surgery. Nevertheless, few reports in the literature describe the ability of the iliac crest to regenerate...
March 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28202207/catastrophic-varus-collapse-of-the-tibia-in-obese-total-knee-arthroplasty
#7
Thomas K Fehring, Keith A Fehring, Lucas A Anderson, Jesse E Otero, Bryan D Springer
BACKGROUND: Mechanical complications have been underemphasized in reports on total knee arthroplasty (TKA) in obese patients. Noticing an increased prevalence of varus collapse of the tibia in obese total knee patients, we sought to determine if variability in proximal tibial cancellous bone strength played a role in failure. We attempted to define a cancellous threshold above which alternative methods of fixation should be used. METHODS: One thousand one hundred six revision TKAs from 2004-2014 identified 35 patients with varus collapse of the tibia, defined as a change in component position of >10°...
January 30, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28199936/the-longitudinal-split-technique-for-narrow-canal-tibia-in-a-case-of-distal-femur-replacement-for-osteosarcoma
#8
Toru Akiyama, Shotaro Kanda, Kazuo Saita
INTRODUCTION: There are currently no available prostheses that can be used for extremely small femurs or tibias of adult patients in countries where allograft is unavailable. CASE REPORT: We report the case of a 17-year-old girl requiring special limb salvage technique for distal femur reconstruction following resection of malignant tumor. This technique was needed because of a very narrow canal of the tibia. We split bilateral tibial cortices longitudinally with osteotomies to enlarge tibial canal enough to insert conventional endoprosthesis...
January 31, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28197822/enhanced-repair-of-segmental-bone-defects-in-rabbit-radius-by-porous-tantalum-scaffolds-modified-with-the-rgd-peptide
#9
Hui Wang, Qijia Li, Qian Wang, Hui Zhang, Wei Shi, Hongquan Gan, Huiping Song, Zhiqiang Wang
Fast and stable repair of segmental bone defects remains a challenge for clinical orthopedic surgery. In recent years, porous tantalum has been widely applied in clinical orthopedics for low modulus of elasticity, with three-dimensional microstructures similar to cancellous bone and excellent biocompatibility. To further improve bone the repairing ability of porous tantalum, the cyclo(-RGDfK-) peptide was coated on the surface of porous tantalum scaffolds. A model of 15 mm segmental defect was made at the midshaft of right radius in New Zealand White rabbits...
March 2017: Journal of Materials Science. Materials in Medicine
https://www.readbyqxmd.com/read/28196162/the-use-of-recombinant-human-platelet-derived-growth-factor-for-maxillary-sinus-augmentation
#10
Atsushi Kubota, Hector Sarmiento, Mohammed Saad Alqahtani, Arturo Llobell, Joseph P Fiorellini
The maxillary sinus augmentation procedure has become a predictable treatment to regenerate bone for implant placement. The purpose of this study was to evaluate the effect of recombinant human platelet-derived growth factor BB (rhPDGF-BB) combined with a deproteinized cancellous bovine bone graft for sinus augmentation. The lateral window approach was used for maxillary sinuses with minimal residual bone. After a healing period of 4 months, dental implants were placed and then restored following a 2-month osseointegration period...
March 2017: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/28194480/evaluation-of-bone-mineral-density-and-microarchitectural-parameters-by-dxa-and-hr-pqct-in-37-children-and-adults-with-x-linked-hypophosphatemic-rickets
#11
G P Colares Neto, R M R Pereira, J C Alvarenga, L Takayama, M F A Funari, R M Martin
: In X-linked hypophosphatemic (XLH) rickets, dual-energy X-ray absorptiometry (DXA) measurements must be analyzed with caution. High-resolution peripheral quantitative computed tomography (HR-pQCT) analysis suggested that XLH primarily affects the cancellous compartment, with the tibia more affected than the radius. Effective treatment of XLH appears to positively affect bone mineralization, mainly in the bone cortex. INTRODUCTION: The purpose of this study is to evaluate bone mineral density (BMD) and microarchitecture in 37 patients (13 children and 24 adults) with XLH confirmed by PHEX mutations from a tertiary center compared to healthy controls...
February 13, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28183620/multilayer-porous-uhmwpe-scaffolds-for-bone-defects-replacement
#12
A V Maksimkin, F S Senatov, N Yu Anisimova, M V Kiselevskiy, D Yu Zalepugin, I V Chernyshova, N A Tilkunova, S D Kaloshkin
Reconstruction of the structural integrity of the damaged bone tissue is an urgent problem. UHMWPE may be potentially used for the manufacture of porous implants simulating as closely as possible the porous cancellous bone tissue. But the extremely high molecular weight of the polymer does not allow using traditional methods of foaming. Porous and multilayer UHMWPE scaffolds with nonporous bulk layer and porous layer that mimics cancellous bone architecture were obtained by solid-state mixing, thermopressing and washing in subcritical water...
April 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28182095/early-detection-of-tibial-cartilage-degradation-and-cancellous-bone-loss-in-an-ovariectomized-rat-model
#13
Yinong Wang, Zhiwei Liu, Qing Wang, Qianjin Feng, Wufan Chen
This study aimed to investigate degradation of the articular cartilage and loss of the cancellous bone in an ovariectomized (OVX) rat model simulating early human menopausal stage. Fourteen health female Sprague-Dawley rats were randomly divided into two groups (n = 7 per group): an OVX group that underwent bilateral ovariectomy to create an OVX model with low estrogen levels and a sham group in which only the periovarian fatty tissue was exteriorized. All the animals were sacrificed at 3 weeks after ovariectomy...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28174633/long-term-follow-up-of-autogenous-tooth-bone-graft-blocks-with-dental-implants
#14
Young-Kyun Kim, Kang-Mi Pang, Pil-Young Yun, Dae-Ho Leem, In-Woong Um
Demineralized dentin matrix block (ABTB: Autogenous Tooth Bone Graft Block) is 3-D scaffold with same components and geometry with alveolar bone. ABTB is well incorporated and remodelled into cortico-cancellous bone with dental implant. The shape and volume were maintained with little marginal bone loss after average 44 months of follow-up.
February 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/28171811/diametral-compression-behavior-of-biomedical-titanium-scaffolds-with-open-interconnected-pores-prepared-with-the-space-holder-method
#15
B Arifvianto, M A Leeflang, J Zhou
Scaffolds with open, interconnected pores and appropriate mechanical properties are required to provide mechanical support and to guide the formation and development of new tissue in bone tissue engineering. Since the mechanical properties of the scaffold tend to decrease with increasing porosity, a balance must be sought in order to meet these two conflicting requirements. In this research, open, interconnected pores and mechanical properties of biomedical titanium scaffolds prepared by using the space holder method were characterized...
January 31, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28168137/arthroscopically-assisted-evacuation-of-brodie-s-abscess-of-distal-femur
#16
Rajeev R Manandhar, Shisir Lakhey, Sagar Panthi, Kiran P Rijal
Brodie's abscess is a type of subacute osteomyelitis. Opinions differ as to whether treatment should be surgical or medical for these classic lesions. Failure of symptoms to resolve after six weeks of antibiotics or worsening of the condition during treatment should be followed by surgical treatment. Clinical signs of subperiosteal pus or synovitis indicate that the subacute infection has transformed into an acute component, and it must be drained surgically. Surgical treatment is comprised of evacuation and curettage for small lesions and evacuation, packing with cancellous bone chips, for large cavities...
January 6, 2017: Curēus
https://www.readbyqxmd.com/read/28166705/high-tibial-osteotomy-combined-with-cancellous-bone-graft-and-osteochondral-autograft-transplantation-in-a-patient-with-massive-osteochondral-defects-in-the-medial-femoral-condyle
#17
Takehiko Matsushita, Shu Watanabe, Daisuke Araki, Tomoyuki Matsumoto, Koji Takayama, Masahiro Kurosaka, Ryosuke Kuroda
Treatment of massive osteochondral defects of the medial femoral condyle is challenging. A 46-year-old man who had a medial femoral condyle fracture on his left knee underwent osteosynthesis in a hospital, but the pain remained and the patient was referred to our hospital 8 months after the surgery. Radiographs showed a varus alignment of the leg, and magnetic resonance image showed a massive necrotic area in the medial femoral condyle. The patient received high tibial osteotomy (HTO) combined with iliac cancellous bone graft and an osteochondral autograft transplantation...
January 2017: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/28165587/femoral-impaction-allografting-for-significant-bone-loss-in-revision-hip-arthroplasty
#18
Thomas A J Goff, Peter Bobak
INTRODUCTION: Femoral impaction bone allografting in revision hip arthroplasty facilitates physiological reconstruction with restoration of bone stock, allowing implantation of a standard cemented femoral component. The purpose of this study was to report our experience in femoral component revision arthroplasty with impaction morsellised cancellous bone allograft using custom impactors and a cemented triple-taper polished stem. METHODS: Retrospective analysis of all cases of femoral component revision hip arthroplasty with impaction bone grafting undertaken by a single surgeon from 2005 to 2011...
February 1, 2017: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/28160577/the-effects-of-surgical-preparation-techniques-and-implant-macro-geometry-on-primary-stability-an-in-vitro-study
#19
G Falisi, M Severino, C Rastelli, S Bernardi, S Caruso, M Galli, L Lamazza, C Di Paolo
BACKGROUND: The attainment of a good primary stability is a necessary condition to ensure the success of osseointegration in implantology. In type IV cancellous bone, however, it is possible that a reduced primary stability can lead to an increased rate of failure. The aim of this study was therefore to determine, with the help of the resonance frequency (Osstell mentor), which technique of implant site preparation (piezo surgery, conventional, under-preparation, bone compaction, osteodistraction) and macro-geometry is able to improve implant stability in type IV cancellous bone...
February 4, 2017: Medicina Oral, Patología Oral y Cirugía Bucal
https://www.readbyqxmd.com/read/28159451/interfragmentary-compression-and-pull-out-properties-of-6-5-mm-ao-cancellous-lag-screws-in-a-uniform-synthetic-material-during-tightening-procedures
#20
Peidong Sun, Daqiang Xu, Weidong Zhao, Peifeng Jiao, Zeyu Li, Chang Liu, Jun Ouyang
AO lag screws are widely used in surgical intra-articular fracture treatment for anatomical reduction and rigid fixation. Interfragmentary compressive force (IFCF) and pull-out strength (POS) are two critical parameters generated by AO lag screws during tightening, and both of these parameters could be used to estimate screw insert conditions to prevent screw stripping. The aim of this study is to evaluate the IFCF and POS of AO cancellous screws inserted into uniform synthetic cancellous bone during tightening procedures...
January 31, 2017: Medical Engineering & Physics
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