Agnieszka Tomczyk-Warunek, Karolina Turżańska, Agnieszka Posturzyńska, Filip Kowal, Tomasz Blicharski, Inés Torné Pano, Anna Winiarska-Mieczan, Anna Nikodem, Sławomir Dresler, Ireneusz Sowa, Magdalena Wójciak, Piotr Dobrowolski
Osteoporosis stands out as a prevalent skeletal ailment, prompting exploration into potential treatments, including dietary strontium ion supplements. This study assessed the efficacy of supplementation of three strontium forms-strontium citrate (SrC), strontium ranelate (SrR), and strontium chloride (SrCl)-for enhancing bone structure in 50 female SWISS mice, aged seven weeks. In total, 40 mice underwent ovariectomy, while 10 underwent sham ovariectomy. Ovariectomized (OVX) mice were randomly assigned to the following groups: OVX (no supplementation), OVX + SrR, OVX + SrC, and OVX + SrCl, at concentrations equivalent to the molar amount of strontium...
April 6, 2024: International Journal of Molecular Sciences