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Guiyan Wang, Chao Wang, Man Qin
BACKGROUND/AIM: Complicated crown fractures are relatively common in children where the maintenance of the pulp is especially important in young permanent teeth. The aim of this study was to analyze the pulp prognosis of permanent teeth with complicated crown fractures treated with conservative pulp treatment in adolescents. MATERIAL AND METHODS: Complete dental records of teeth with complicated crown fractures treated with conservative pulp treatment were obtained...
February 24, 2017: Dental Traumatology: Official Publication of International Association for Dental Traumatology
Reinhold Feldmann, Eva Wolfgart, Josef Weglage, Frank Rutsch
AIM: Sapropterin causes reductions in blood phenylalanine concentrations in sensitive patients with phenylketonuria (PKU),. We examined whether the subsequent relaxation of dietary restrictions influenced the quality of life (QoL) of patients and parents. METHODS: The study cohort comprised 112 patients with PKU followed at the metabolic centre at Münster University Children's Hospital, Germany, from 2012 to 2015. A sapropterin response was defined as a ≥30% reduction in blood phenylalanine levels...
February 24, 2017: Acta Paediatrica
Yan Chen, Hongyu Wang, Gary Wk Wong, Nanshan Zhong, Jing Li
BACKGROUND: Few studies have assessed the time trends of prevalence of symptoms of rhinitis (SR) with wheezing and their associations in Chinese adolescents. OBJECTIVE: To explore the trend of prevalence of SR with wheezing and allergen sensitization in adolescents during the past 15 years. METHODS: A total of 7165 adolescents aged 13-14 years in 2009 were recruited for the study using the Phase III Protocol of the International Study of Asthma and Allergic disease in Childhood (ISAAC) and allergic sensitization to seven inhalant allergens in 2531 was assessed by skin prick test in 2010...
February 24, 2017: Pediatric Allergy and Immunology
Jessica Burkhamer, David Kriebel, Richard Clapp
Cancer incidence is rising among adolescents ("teens"). The causes of the increase are unknown but studying incidence patterns and trends may produce insights into etiology. Using data from the US National Cancer Institute's Surveillance, Epidemiology, and End Results (SEER) program we described trends of cancer incidence among teens (15-19 year olds). We reviewed and summarized incidence patterns for histologic cancer groups and the most frequently diagnosed sites of cancer among teens during 2008-2012 reported by the SEER Cancer Statistics Review...
2017: PloS One
Reuben Musarandega, Rhoderick Machekano, Memory Chideme, Cephas Muchuchuti, Angela Mushavi, Agnes Mahomva, Laura Guay
BACKGROUND: Age-disaggregated analyses of prevention of mother-to-child transmission (PMTCT) program data to assess the uptake of HIV services by pregnant adolescent women are limited but are critical to understanding the unique needs of this vulnerable, high risk population. METHODS: We conducted a retrospective analysis of patient-level PMTCT data collected from 2011 to 2013 in 36 health facilities in 5 districts of Zimbabwe using an electronic database. We compared uptake proportions for PMTCT services between adolescent (< 19 years) and adult (> 19 years) women...
February 20, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
Marie-Pierre Sylvestre, Khady Kâ, Erika N Dugas, Michael Zappitelli, Jennifer O'Loughlin
BACKGROUND AND OBJECTIVE: High blood pressure early in life is associated with cardiovascular disease morbidity and mortality in adulthood. The objective was to identify sex-specific trajectories of SBP and DBP from early adolescence to early adulthood and to assess the impact of modifiable factors on the trajectories, including BMI, smoking, alcohol use, physical activity, and screen-time. METHODS: Data were drawn from four waves of a prospective investigation of 1294 youth aged 12-13 years at inception and followed until age 24 years...
February 22, 2017: Journal of Hypertension
Qiang Feng, Chongmin Jiang, Yu Zhou, Yun Huang, Ming Zhang
CONTEXT: Non-specific back pain has become a public health problem affecting adolescent health. OBJECTIVE: To examine the relationships between abnormalities in spinal morphology and non-specific back pain among adolescents. DESIGN: Cross-sectional study. SETTING: Junior and senior high schools. PATIENTS: Participants were screened using a questionnaire regarding back pain. Students in the pain group (n= 273, 121 boys and 152 girls) reported experiencing upper and/or lower back pain within the previous month, and those who did not report pain were assigned to the group without pain (n= 127, 63 boys and 64 girls)...
February 10, 2017: Journal of Back and Musculoskeletal Rehabilitation
Julian Koenig, Lena Rinnewitz, Marco Warth, Thomas K Hillecke, Romuald Brunner, Franz Resch, Michael Kaess
BACKGROUND: Nonsuicidal self-injury (NSSI) is associated with reduced pain sensitivity and alterations in top-down processing of nociceptive information. The experience of acute pain is characterized by reactivity of the autonomic nervous system (ANS) and hypothalamic-pituitary-adrenal (HPA) axis, which to our knowledge has not been systematically investigated in the context of NSSI. METHODS: Adolescents fulfilling DSM-5 diagnostic criteria for NSSI and matched healthy controls received cold pain stimulation...
November 28, 2016: Journal of Psychiatry & Neuroscience: JPN
Dennis van der Meer, Catharina A Hartman, Daan van Rooij, Barbara Franke, Dirk J Heslenfeld, Jaap Oosterlaan, Stephen V Faraone, Jan K Buitelaar, Pieter J Hoekstra
BACKGROUND: Attention-deficit/hyperactivity disorder (ADHD) is often accompanied by impaired response inhibition; both have been associated with aberrant dopamine signalling. Given that prenatal exposure to alcohol or smoking is known to affect dopamine-rich brain regions, we hypothesized that individuals carrying the ADHD risk alleles of the dopamine receptor D4 (DRD4) and dopamine transporter (DAT1) genes may be especially sensitive to their effects. METHODS: Functional MRI data, information on prenatal adversities and genetic data were available for 239 adolescents and young adults participating in the multicentre ADHD cohort study NeuroIMAGE (average age 17...
January 23, 2017: Journal of Psychiatry & Neuroscience: JPN
Julia Dodd, Heather Littleton
Sexual victimization is associated with risky sexual behaviors. Limited research has examined mechanisms via which victimization affects risk behaviors, particularly following different types of sexual victimization. This study examined self-worth as a mediator of the relationship between sexual victimization history: contact childhood sexual abuse (CSA), completed rape in adolescence/adulthood (adolescent/adulthood sexual assault [ASA]), and combined CSA/ASA, and two sexual risk behaviors: past year partners and one-time encounters...
February 1, 2017: Violence and Victims
Katie Cyr, Claire Chamberland, Marie-Ève Clément, Jo-Anne Wemmers, Delphine Collin-Vézina, Geneviève Lessard, Marie-Hélène Gagné, Dominique Damant
This study documents lifetime experiences of victimizations, polyvictimization, and trauma symptoms among 1,400 adolescents from the province of Québec. The vast majority (81%) of adolescents were victimized during their lifetime, with most victims (82%) being the target of more than one form of victimization. Polyvictimization accounted for most variability in scores of depression, posttraumatic stress disorder (PTSD), and anger/ aggression compared to individual victimization categories. Sexual victimization and maltreatment still made an independent contribution in predicting all trauma scores once polyvictimization was considered...
February 1, 2017: Violence and Victims
Fausto Yoshio Matsumoto, Tessa Rachel Tranquillini Gonçalves, Dirceu Solé, Gustavo Falbo Wandalsen
BACKGROUND: Currently, the diagnosis of allergic rhinitis (AR) is arrived at predominantly by a clinical history and by systemic sensitization tests, but specific nasal provocation tests (NPT) may establish a better direct correlation between etiologic surveyed allergens and nasal symptoms. OBJECTIVES: To standardize the specific NPT with one of the most important house-dust mites, Dermatophagoides pteronyssinus, monitored by acoustic rhinometry, in children and adolescents, and propose a simplified specific NPT to improve its clinical applicability as a diagnostic tool...
January 1, 2017: American Journal of Rhinology & Allergy
Ahmed M Megreya, Markus Bindemann
No abstract text is available yet for this article.
February 24, 2017: Scientific Reports
Esmeralda Colino, María Martín Frías, Belén Roldán, María Ángeles Álvarez, Rosa Yelmo, Raquel Barrio
OBJECTIVE: The aims of the study are to evaluate the efficacy and safety of continuous subcutaneous insulin infusion (CSII) treatment in pre-school children with type I diabetes, and to assess whether the criteria of good metabolic control are achieved. METHOD: A review was performed on the medical charts of patient's<6 years of age who started CSII treatment between 2003 and 2014. The cohort consisted of 27 patients (mean age 4 (2.9-4.7) years, 56% males). An analysis was made including the age at onset, type I diabetes duration, HbA1c (HPLC, Menarini, normal value 5...
February 20, 2017: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
Samuel Chalmers, Joel T Fuller, Thomas A Debenedictis, Samuel Townsley, Matthew Lynagh, Cara Gleeson, Andrew Zacharia, Stuart Thomson, Mary Magarey
OBJECTIVES: The Functional Movement Screen (FMS) is a popular screening tool, however, the postulated relationship between prospective injury and FMS scoring remains sparsely explored in adolescent athletes. The aim of the study was to examine the association between pre-season FMS scores and injuries sustained during one regular season competition in elite adolescent Australian football players. DESIGN: Prospective cohort study. METHODS: 237 elite junior Australian football players completed FMS testing during the late pre-season phase and had their weekly playing status monitored during the regular season...
January 24, 2017: Journal of Science and Medicine in Sport
Vibeke Strand, Jasvinder A Singh
Axial spondyloarthritis (AxSpA) is a chronic inflammatory rheumatic disease characterized by inflammatory back pain (IBP) that manifests in childhood, late adolescence, or early adulthood. Ankylosing spondylitis (AS) and nonradiographic AxSpA represent 2 ends of the AxSpA spectrum. Diagnosis can be challenging because patients develop IBP that may not be associated with radiographic changes in the sacroiliac joints. Patients early in the course of disease are estimated to have at least the same level of disease activity and pain as patients with established disease; thus, they could benefit substantially from earlier diagnosis...
February 20, 2017: Mayo Clinic Proceedings
Hugo Rodríguez, Giselle Cuestas, Mariana Álvarez, Maira Monaje
No abstract text is available yet for this article.
February 20, 2017: Acta Otorrinolaringológica Española
Ting Liu, Jeffrey Fuller, Alison Hutton, Julian Grant
Chinese adolescents are increasingly engaging in romantic experiences and high-risk sexual behaviors within a rapidly-changing cultural and socio-economic context. Parental communication about sexuality has been recognized as protective for adolescents to make informed decisions about sexual practice. In this study, we explored what was discussed about adolescent romantic experience between parents and adolescents in China. Twenty-seven parents and 38 adolescents from a northern-eastern city of China were interviewed...
February 24, 2017: Nursing & Health Sciences
A Iorio, S Krishnan, K J Myrén, S Lethagen, N McCormick, S Yermakov, P Karner
INTRODUCTION: Recombinant factor VIII (rFVIII) products with extended half-lives have the potential to improve adherence and outcomes in haemophilia beyond the results obtained with conventional rFVIII products. AIM: In the absence of head-to-head comparisons, annualized bleed rates (ABRs) and weekly factor consumption with rFVIII Fc fusion protein (rFVIIIFc) and conventional rFVIII products were indirectly compared using studies of continuous prophylaxis. METHODS: A systematic literature review was conducted to identify studies of rFVIII products for comparison with rFVIIIFc in the continuous prophylactic treatment of previously treated adolescents and adults with moderate and severe haemophilia A...
February 24, 2017: Haemophilia: the Official Journal of the World Federation of Hemophilia
A Tiede, F Abdul-Karim, M Carcao, P Persson, W H O Clausen, S Kearney, T Matsushita, C Negrier, J Oldenburg, E Santagostino, G Young
INTRODUCTION: Nonacog beta pegol (N9-GP) is a glycoPEGylated recombinant factor IX (FIX) with an extended half-life developed for routine prophylaxis and the prevention and treatment of bleeding episodes in patients with haemophilia B. AIM: The aim of this study was to evaluate the pharmacokinetics (PK) of N9-GP. METHODS: Data from 41 previously treated haemophilia B patients, enrolled globally (16 adolescents/adults and 25 children; FIX activity ≤0...
February 24, 2017: Haemophilia: the Official Journal of the World Federation of Hemophilia
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