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https://www.readbyqxmd.com/read/28822894/increased-minimum-legal-age-for-the-sale-of-alcohol-in-the-netherlands-as-of-2014-the-effect-on-alcohol-sellers-compliance-after-one-and-two-years
#1
Karen Schelleman-Offermans, Ruud T J Roodbeen, Paul H H M Lemmens
BACKGROUND: As of January 2014, the Dutch minimum legal age for the sale and purchase of all alcoholic beverages has increased from 16 to 18 years of age. The effectiveness of a minimum legal age policy in controlling the availability of alcohol for adolescents depends on the extent to which this minimum legal age is complied with in the field. The main aim of the current study is to investigate, for a country with a West-European drinking culture, whether raising the minimum legal age for the sale of alcohol has influenced compliance rates among Dutch alcohol vendors...
August 17, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/28822801/microarray-gene-expression-study-in-fibroblast-and-lymphoblastoid-cell-lines-from-antipsychotic-na%C3%A3-ve-first-episode-schizophrenia-patients
#2
Patricia Gassó, Sergi Mas, Natalia Rodríguez, Daniel Boloc, Susana García-Cerro, Miquel Bernardo, Amalia Lafuente, Eduard Parellada
Schizophrenia (SZ) is a chronic psychiatric disorder whose onset of symptoms occurs in late adolescence and early adulthood. The etiology is complex and involves important gene-environment interactions. Microarray gene-expression studies on SZ have identified alterations in several biological processes. The heterogeneity in the results can be attributed to the use of different sample types and other important confounding factors including age, illness chronicity and antipsychotic exposure. The aim of the present microarray study was to analyze, for the first time to our knowledge, differences in gene expression profiles in 18 fibroblast (FCLs) and 14 lymphoblastoid cell lines (LCLs) from antipsychotic-naïve first-episode schizophrenia (FES) patients and healthy controls...
August 5, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28822746/outcomes-of-early-adolescent-donor-hearts-in-adult-transplant-recipients
#3
Shivank Madan, Snehal R Patel, Peter Vlismas, Omar Saeed, Sandhya Murthy, Stephen Forest, William Jakobleff, Daniel Sims, Jacqueline M Lamour, Daphne T Hsu, Julia Shin, Daniel Goldstein, Ulrich P Jorde
OBJECTIVES: This study sought to determine outcomes of adult recipients of early adolescent (EA) (10 to 14 years) donor hearts. BACKGROUND: Despite a shortage of donor organs, EA donor hearts (not used for pediatric patients) are seldom used for adults because of theoretical concerns for lack of hormonal activation and changes in left ventricular mass. Nonetheless, the outcomes of adult transplantation using EA donor hearts are not clearly established. METHODS: All adult (≥18 years of age) heart transplant recipients in the United Network for Organ Sharing database between April 1994 and September 2015 were eligible for this analysis...
August 3, 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28822742/strategy-set-shifting-and-response-inhibition-in-adult-rats-exposed-to-an-environmental-polychlorinated-biphenyl-mixture-during-adolescence
#4
Supida Monaikul, Paul Eubig, Stan Floresco, Susan Schantz
Converging evidence from studies with animal models and humans suggests that early developmental exposure to polychlorinated biphenyls (PCBs) leads to deficits in cognitive flexibility and inhibitory control. These processes are mediated to a large extent by the prefrontal cortex, thus we examined the effects of PCB exposure during adolescence-a period of robust prefrontal cortical development-on both processes. Specifically, we used operant set-shifting and differential reinforcement of low rates of responding (DRL) tasks to assess cognitive flexibility and response inhibition, respectively...
August 16, 2017: Neurotoxicology and Teratology
https://www.readbyqxmd.com/read/28822712/socioeconomic-inequality-in-childhood-obesity-and-its-determinants-in-iran-a-blinder-oaxaca-decomposition
#5
Roya Kelishadi, Mostafa Qorbani, Ramin Heshmat, Shirin Djalalinia, Ali Sheidaei, Saeid Safiri, Nastaran Hajizadeh, Mohammad Esmaeil Motlagh, Gelayol Ardalan, Hamid Asayesh, Morteza Mansourian
OBJECTIVE: Childhood obesity has become a priority health concern worldwide. Socioeconomic status (SES) is one of its main determinants. This study aimed to assess the socioeconomic inequality of obesity in children and adolescents at national and provincial levels in Iran. METHODS: This multicenter cross-sectional study was conducted in 2011-2012, as part of a national school-based surveillance program performed in 40,000 students, aged 6-18-years, from urban and rural areas of 30 provinces of Iran...
August 17, 2017: Jornal de Pediatria
https://www.readbyqxmd.com/read/28822682/a-systematic-review-of-digital-interventions-for-improving-the-diet-and-physical-activity-behaviors-of-adolescents
#6
REVIEW
Taylor Rose, Mary Barker, Chandni Maria Jacob, Leanne Morrison, Wendy Lawrence, Sofia Strömmer, Christina Vogel, Kathryn Woods-Townsend, David Farrell, Hazel Inskip, Janis Baird
Many adolescents have poor diet and physical activity behaviors, which can lead to the development of noncommunicable diseases in later life. Digital platforms offer inexpensive means of delivering health interventions, but little is known about their effectiveness. This systematic review was conducted to synthesize evidence on the effectiveness of digital interventions to improve diet quality and increase physical activity in adolescents, to effective intervention components and to assess the cost-effectiveness of these interventions...
August 16, 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/28822681/firearm-storage-practices-in-households-of-adolescents-with-and-without-mental-illness
#7
Joseph A Simonetti, Mary Kay Theis, Ali Rowhani-Rahbar, Evette J Ludman, David C Grossman
PURPOSE: Safe firearm storage practices are associated with a lower risk of self-inflicted injury and death. Whether such practices and relevant beliefs differ between households of adolescents with and without mental illness is unknown. METHODS: We used survey and administrative data to perform a two-stage cross-sectional study of parents/guardians of adolescents who were 11-17 years, enrolled in a managed care plan in 2004 and living in a household with a firearm...
August 16, 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/28822592/use-of-gabapentin-and-pregabalin-for-pruritus-and-neuropathic-pain-associated-with-major-burn-injury-a-retrospective-chart-review
#8
Isha Kaul, Ami Amin, Marta Rosenberg, Laura Rosenberg, Walter J Meyer
INTRODUCTION: Pruritis after burn is one of the most common chronic complaints in burn survivors. Pruritus is often indistinguishable from neuropathic pain. There is a paucity of studies reporting the use of gabapentin and pregabalin to treat both pruritus and neuropathic pain. The purpose of this current study is to explore and document the effect of gabapentin and pregabalin in children and adolescent burn survivors. METHODS: A retrospective review of charts and pharmacy records of gabapentin and pregabalin dispensed to control pruritus and/or pain was conducted for burn survivors up to 20 years of age...
August 16, 2017: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/28822514/anthropometric-indicators-as-predictor-of-pre-diabetes-in-indian-adolescents
#9
Umeshwar Pandey, Tanu Midha, Yashwant Kumar Rao, Pravin Katiyar, Pranay Wal, Samarjeet Kaur, Dinesh Singh Martolia
INTRODUCTION: In India, there are approximately 41 million diabetics to date. Impaired glucose tolerance or pre-diabetes may occur as early as adolescence. OBJECTIVE: To find out the cut-off values of body mass index (BMI) and waist circumference to predict pre-diabetes in adolescents in north India. METHODS: A cross-sectional study was conducted among 526 students aged 17-19 years, in the Institute of Paramedical Sciences, Chatrapati Shahuji Maharaj University, Kanpur...
July 2017: Indian Heart Journal
https://www.readbyqxmd.com/read/28822477/spinal-manipulative-therapy-for-adolescent-idiopathic-scoliosis-a-systematic-review
#10
Jean Théroux, Norman Stomski, Christine Dominique Losco, Christelle Khadra, Hubert Labelle, Sylvie Le May
OBJECTIVE: The purpose of this study was to perform a systematic review of clinical trials of spinal manipulative therapy for adolescent idiopathic scoliosis. METHODS: Search strategies were developed for PubMed, CINHAL, and CENTRAL databases. Studies were included through June 2016 if they were prospective trials that evaluated spinal manipulative therapy (eg, chiropractic, osteopathic, physical therapy) for adolescent idiopathic scoliosis. Data were extracted and assessed by 2 independent reviewers...
July 2017: Journal of Manipulative and Physiological Therapeutics
https://www.readbyqxmd.com/read/28822476/posture-alignment-of-adolescent-idiopathic-scoliosis-photogrammetry-in-scoliosis-school-screening
#11
Patrícia Jundi Penha, Nárima Lívia Jundi Penha, Bárbarah Kelly Gonçalves De Carvalho, Rodrigo Mantelatto Andrade, Ana Carolina Basso Schmitt, Sílvia Maria Amado João
OBJECTIVE: The objective of this study was to describe the posture patterns of adolescents diagnosed with adolescent idiopathic scoliosis (AIS) in a scoliosis school screening (SSS). METHODS: Two-dimensional photogrammetry was used to assess the posture of 37 adolescents diagnosed with scoliosis (scoliosis group, SG) (Cobb angle ≥10°) and 76 adolescents with a false positive diagnosis (false positive group, FPG) (Cobb angle <10°, angle of trunk rotation ≥7°)...
July 2017: Journal of Manipulative and Physiological Therapeutics
https://www.readbyqxmd.com/read/28822064/evolution-of-29-anthropometric-nutritional-and-cardiometabolic-parameters-among-morbidly-obese-adolescents-2-years-post-sleeve-gastrectomy
#12
Wahiba Elhag, Walid El Ansari, Sama Abdulrazzaq, Ali Abdullah, Mohamed Elsherif, Israa Elgenaied
BACKGROUND: Laparoscopic sleeve gastrectomy (LSG) is a popular treatment for adolescent morbid obesity. Research on LSG outcomes among adolescents assessed a narrow range of anthropometric, nutritional, or cardiometabolic parameters, leading to an incomplete picture of these changes. We examined a wide variety of anthropometric, nutritional, and cardiometabolic parameters among adolescents before and after LSG. METHODS: We retrospectively reviewed medical charts of all obese adolescents who underwent LSG at Hamad Medical Corporation, Qatar, between January 2011 and June 2015 (N = 102)...
August 18, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28821907/immigration-to-israel-during-childhood-is-associated-with-diabetes-at-adolescence-a-study-of-2-7-million-adolescents
#13
Alon Peled, Barak Gordon, Gilad Twig, Joseph Mendlovic, Estela Derazne, Michal Lisnyansky, Itamar Raz, Arnon Afek
AIMS/HYPOTHESIS: Immigration studies can shed light on diabetes pathogenesis and risk factors. To this end, we investigated the association between age at immigration and diabetes occurrence at adolescence among immigrants to Israel. METHODS: We analysed cross-sectional data on 2,721,767 Jewish adolescents assessed for mandatory military service at approximately 17 years of age between 1967 and 2014. The study population comprised 430,176 immigrants with origins in Ethiopia, former USSR, Middle East and North Africa (ME/NA) and western countries...
August 19, 2017: Diabetologia
https://www.readbyqxmd.com/read/28821895/osteonecrosis-in-adolescents-and-young-adults-with-acute-lymphoblastic-leukaemia-on-hong-kong-singapore-acute-lymphocytic-leukaemia-97-protocol
#14
Bryan Mh Keng, Gee Chuan Wong
No abstract text is available yet for this article.
July 2017: Annals of the Academy of Medicine, Singapore
https://www.readbyqxmd.com/read/28821748/anxiety-related-experience-dependent-white-matter-structural-differences-in-adolescence-a-monozygotic-twin-difference-approach
#15
Nagesh Adluru, Zhan Luo, Carol A Van Hulle, Andrew J Schoen, Richard J Davidson, Andrew L Alexander, H Hill Goldsmith
Anxiety is linked to deficits in structural and functional connectivity between limbic structures and pre-frontal cortices. We employed a monozygotic (MZ) twin difference design to examine the relationship between structural characteristics of the uncinate fasciculus (UF) measured by Diffusion Tensor Imaging (DTI) and anxiety symptoms in a sample of N = 100 monozygotic (genetically identical), adolescent twins. The MZ difference design allowed us focus on environmental factors that vary within twin pairs while controlling for genetic and environmental factors shared by twin pairs...
August 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28821657/fronto-parietal-structural-connectivity-in-childhood-predicts-development-of-functional-connectivity-and-reasoning-ability-a-large-scale-longitudinal-investigation
#16
Carter Wendelken, Emilio Ferrer, Simona Ghetti, Stephen Bailey, Laurie Cutting, Silvia A Bunge
Prior research points to a positive concurrent relationship between reasoning ability and both fronto-parietal structural connectivity, as measured by diffusion tensor imaging (e.g. Tamnes et al., 2010), and fronto-parietal functional connectivity, as measured by fMRI (e.g. Cocchi et al., 2014). Further, recent research demonstrates a link between reasoning ability and functional connectivity of two brain regions in particular: rostrolateral prefrontal cortex (RLPFC) and the inferior parietal lobe (IPL) (Wendelken et al...
August 7, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28821523/effectiveness-of-a-pragmatic-school-based-universal-resilience-intervention-in-reducing-tobacco-alcohol-and-illicit-substance-use-in-a-population-of-adolescents-cluster-randomised-controlled-trial
#17
Rebecca Kate Hodder, Megan Freund, Jenny Bowman, Luke Wolfenden, Elizabeth Campbell, Julia Dray, Christophe Lecathelinais, Christopher Oldmeadow, John Attia, John Wiggers
OBJECTIVES: Initiation of tobacco, alcohol and illicit substance use typically occurs during adolescence, with the school setting recommended to reduce adolescent substance use. Strengthening individual (eg, problem solving) and environmental (eg, caring relationships at school) resilience protective factors of adolescents has been suggested as a strategy for reducing substance use by adolescents; however, few studies have examined this potential. A study was conducted to investigate the effectiveness of a pragmatic school-based universal 'resilience' intervention in reducing the prevalence of tobacco, alcohol and illicit substance use, and increasing the individual and environmental protective factors of students...
August 18, 2017: BMJ Open
https://www.readbyqxmd.com/read/28821522/evidence-of-pharmacological-and-non-pharmacological-interventions-for-the-management-of-dental-fear-in-paediatric-dentistry-a-systematic-review-protocol
#18
Stefano Cianetti, Luigi Paglia, Roberto Gatto, Alessandro Montedori, Eleonora Lupatelli
INTRODUCTION: Several techniques have been proposed to manage dental fear/dental anxiety (DFA) in children and adolescents undergoing dental procedures. To our knowledge, no widely available compendium of therapies to manage DFA exists. We propose a study protocol to assess the evidence regarding pharmacological and non-pharmacological interventions to relieve dental anxiety in children and adolescents. METHODS AND ANALYSIS: In our systematic review, we will include randomised trials, controlled clinical rials and systematic reviews (SRs) of trials that investigated the effects of pharmacological and non-pharmacological interventions to decrease dental anxiety in children and adolescents...
August 18, 2017: BMJ Open
https://www.readbyqxmd.com/read/28821519/ten-year-follow-up-of-human-papillomavirus-vaccine-efficacy-against-the-most-stringent-cervical-neoplasia-end-point-registry-based-follow-up-of-three-cohorts-from-randomized-trials
#19
Matti Lehtinen, Camilla Lagheden, Tapio Luostarinen, Tiina Eriksson, Dan Apter, Katja Harjula, Marjo Kuortti, Kari Natunen, Johanna Palmroth, Tiina Petäjä, Eero Pukkala, Mari Siitari-Mattila, Frank Struyf, Pekka Nieminen, Jorma Paavonen, Gary Dubin, Joakim Dillner
OBJECTIVE: Due to long lag time between infection/cancer diagnoses human papillomavirus (HPV) vaccination programs will deliver vaccine efficacy (VE) estimates against cancer end-points late. Cancer registry follow-up of population-based, randomised trial cohorts of vaccinated and unvaccinated women was undertaken for the estimation of VE against cervical intraepithelial neoplasia grade three and invasive cancer (CIN3+). METHODS: We report interim results with 98 561 person years of Finnish Cancer Registry -based follow-up of individually and/or cluster randomised cohorts of HPV-16/18 vaccinated and unvaccinated adolescent women enrolled in June 2003/2005, and between May 2004 and April 2005, respectively...
August 18, 2017: BMJ Open
https://www.readbyqxmd.com/read/28821469/a-cluster-randomized-trial-of-a-middle-school-gender-violence-prevention-program-design-rationale-and-sample-characteristics
#20
Kaleab Z Abebe, Kelley A Jones, Samantha Ciaravino, Lisa Ripper, Taylor Paglisotti, Sarah Elizabeth Morrow, Melanie Grafals, Courtney Van Dusen, Elizabeth Miller
INTRODUCTION: High rates of adolescent relationship abuse (ARA) and sexual violence (SV) reported among adolescents point to the need for prevention among middle school-age youth. This is a cluster randomized controlled trial to test an athletic coach-delivered ARA/SV prevention program in 41 middle schools (38 clusters). Trained coaches talk to their male athletes about 1) what constitutes harmful vs. respectful relationship behaviors, 2) dispelling myths that glorify male sexual aggression and promoting more gender-equitable attitudes, and 3) positive bystander intervention when aggressive male behaviors toward females are witnessed...
August 15, 2017: Contemporary Clinical Trials
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