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Pablo Fernández-Crehuet, Pedro Jesus Gómez-Arias, Ricardo Ruiz-Villaverde
No abstract text is available yet for this article.
September 2018: Australian journal of general practice
Julian Tillmann, John Swettenham
To test a central assumption of the increased perceptual capacity account in individuals with Autism Spectrum Disorder (ASD), the effects of perceptual load and target-stimulus degradation on auditory detection sensitivity were contrasted. Fourteen adolescents with ASD and 16 neurotypical controls performed a visual letter search task under three conditions: low perceptual load, high perceptual load and low perceptual load with a degraded target while simultaneously detecting an auditory tone in noise. For both participants with ASD and neurotypical controls, increasing perceptual load and target degradation increased task difficulty as indexed by reaction times and accuracy...
September 22, 2018: Journal of Autism and Developmental Disorders
A Kagee, B Coetzee, S Du Toit, M E Loades
PURPOSE: Minimal research has been conducted to understand how fatigue influences quality of life (QOL) among adolescents living with HIV. The purpose of the study was to examine the relationship between fatigue, sleep disturbance, depression, anxiety, pain and QOL among adolescents receiving antiretroviral therapy (ART). METHODS: Using a cross-sectional survey design, we studied 134 South African adolescents receiving an ART at community clinics. RESULTS: Participants in general reported low levels of fatigue, insomnia, distress and pain and non-problematic levels of QOL...
September 22, 2018: Quality of Life Research
Marina Panova-Noeva, Marie A Neu, Susan Eckerle, Claudia Spix, Astrid Schneider, Irene Schmidtmann, Henri M Spronk, Norbert Pfeiffer, Manfred Beutel, Karl J Lackner, Thomas Münzel, Hugo Ten Cate, Hiltrud Merzenich, Jörg Faber, Philipp S Wild
Cardiovascular disease is the most frequent non-malignant cause of morbidity and mortality in adult survivors of childhood or adolescent cancer. Thrombin generation (TG) analysis gives insight in hypercoagulability as an important mechanism linked to cardiovascular risk factors (CVRFs). In 200 individuals, from the cardiac and vascular late sequelae in long-term survivors of childhood cancer study, TG in platelet-rich plasma (PRP) and platelet-free plasma (PFP) at 1pM tissue factor was investigated. Endogenous thrombin potential (ETP) and peak height were the analysed parameters of a TG curve...
September 22, 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
Gabriel L Schlomer, H Harrington Cleveland, Arielle R Deutsch, David J Vandenbergh, Mark E Feinberg, Mark T Greenberg, Richard L Spoth, Cleve Redmond
Better integrating human developmental factors in genomic research is part of a set of next steps for testing gene-by-environment interaction hypotheses. This study adds to this work by extending prior research using time-varying effect modeling (TVEM) to evaluate the longitudinal associations between the PROSPER preventive intervention delivery system, a GABRA2 haplotype linked to alcohol use, and their interaction on adolescent delinquency. Logistic and Poisson analyses on eight waves of data spanning ages 11 to 19 (60% female, 90% Caucasian) showed the intervention reduced delinquency from ages 13 to 16...
September 22, 2018: Journal of Youth and Adolescence
Meghan Bowman-Curci, Gwendolyn P Quinn, Joyce Reinecke, Richard R Reich, Susan T Vadaparampil
PURPOSE: The National Comprehensive Cancer Network (NCCN) created guidelines to facilitate implementation of fertility preservation (FP) discussions and referrals for adolescent and young adult patients. We assessed if availability of workplace FP resources and referral policies differed among learners in the Educating Nurses about Reproductive Health in Cancer Healthcare (ENRICH) training program based on NCCN membership. METHODS: Learners completed a baseline application, including demographic information and the availability of FP resources and referral policies...
September 22, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
K E Brodie, V I Alaniz, E M Buyers, B T Caldwell, E C Grantham, J Sheeder, D T Wilcox, P S Huguelet
BACKGROUND: Adolescent females often present to healthcare providers with concerns about the appearance of their external genitalia. These patients may experience significant distress about their genital appearance and may request surgery to correct a perceived abnormality. Accurate descriptions of normal adolescent female genital anatomy are lacking in the literature. OBJECTIVE: The purpose of this study was to examine a small sample of normal adolescent females to obtain measurements and descriptors of the external genital structures, with a focus on the size and morphology of the labia minora...
September 20, 2018: Journal of Pediatric and Adolescent Gynecology
Suying Lu, Jiawang Wei, Feifei Sun, Weiwei Xiao, Ruiqing Cai, Zijun Zhen, Jia Zhu, Juan Wang, Junting Huang, Lixia Lu, Xiaofei Sun, Yuanhong Gao
PURPOSE: The objective of this study was to reveal the long-term sequelae in survivors of childhood and adolescent nasopharyngeal carcinoma (NPC) after radiotherapy. METHODS AND MATERIALS: We reviewed the medical records of NPC patients younger than 18 years old who were treated at XXX from February 1991 to October 2010. Data concerning clinical characteristics, treatment, outcomes, and late morbidities were extracted. Chi-squared tests and binary regression analysis were used to compare the cumulative incidence (CI) of treatment comorbidities between different groups of survivors...
September 20, 2018: International Journal of Radiation Oncology, Biology, Physics
Parinda A Mehta, Seth J Rotz, Navneet S Majhail
A slow but definite progress has been made in recognizing the differences in disease biology, host factors, and psychosocial issues related to management of hematologic malignancies including hematopoietic cell transplantation (HCT) in the adolescent and young adult (AYA) population. Improvement in survival rates among AYAs undergoing HCT for hematologic malignancies have paralleled those among children and older adults in the contemporary era. However, overall outcomes remain inferior compared to children largely due to higher rates of treatment related mortality and late relapses in AYA HCT recipients...
September 19, 2018: Biology of Blood and Marrow Transplantation
Marisa Maia Leonardi-Figueiredo, Hugo Celso Dutra de Souza, Emanuela Juvenal Martins, Monalisa Squiaveto, Ana Claudia Mattiello-Sverzut
BACKGROUND: Cardiovascular autonomic dysfunction is associated with the development of cardiovascular diseases, but little is known about it in children and adolescents with myelomeningocele. OBJECTIVE: This study investigated the cardiovascular autonomic function in wheelchair-using children and adolescents with myelomeningocele. METHODS: Twenty-two participants were assigned to one of two groups: myelomeningocele group (n=11) and Control group (n=11)...
September 15, 2018: Brazilian Journal of Physical Therapy
David Sánchez-Oliva, Alberto Grao-Cruces, Ana Carbonell-Baeza, Verónica Cabanas-Sánchez, Oscar L Veiga, José Castro-Piñero
OBJECTIVES: To identify lifestyle clusters in children and adolescents, to analyze associations between lifestyle clusters and body fat percentage (BFP) at baseline and 2 years later, and to examine if BFP at baseline is associated with BFP 2 years later. STUDY DESIGN: This longitudinal study involved 1634 Spanish youth (804 girls) aged 8-18 years (mean, 12.45 ± 2.51 years). Cluster analysis was performed by including objectively measured sedentary time and physical activity and self-reported screen time and diet...
September 20, 2018: Journal of Pediatrics
Erica C Jansen, Galit Levi Dunietz, Ronald D Chervin, Ana Baylin, Jonggyu Baek, Margaret Banker, Peter X K Song, Alejandra Cantoral, Martha Maria Tellez Rojo, Karen E Peterson
OBJECTIVE: To assess whether adiposity measures differed according to joint categories of sleep duration and sleep variability in a sample of Mexican adolescents. STUDY DESIGN: A sample of 528 Mexico City adolescents aged 9-17 years wore wrist actigraphs for 6-7 days. Average sleep duration was categorized as age-specific sufficient or insufficient. Sleep variability, the standard deviation of sleep duration, was split at the median into stable versus variable. Adiposity measures-body mass index (BMI)-for-age Z score (BMIz), triceps skinfolds, waist circumference, and percent body fat-were collected by trained assistants...
September 20, 2018: Journal of Pediatrics
Kwok W Ng, Pauli Rintala, Pauliina Husu, Jari Villberg, Tommi Vasankari, Sami Kokko
BACKGROUND: Monitoring physical activity among young adolescents with disabilities is a top academic priority. People with disabilities are a diverse group with various abilities in different human functioning. Therefore, we used a novel approach through functional limitations as a marker for disabilities and examined physical activity levels. OBJECTIVE: To investigate the levels and differences in light (LPA) and moderate-to-vigorous (MVPA) intensity physical activity between young adolescents with and without functional limitations...
September 14, 2018: Disability and Health Journal
Kimberly H McManama O'Brien, Christina M Sellers, Adeline Wyman Battalen, Colleen A Ryan, Eleni K Maneta, Laika D Aguinaldo, Erina White, Anthony Spirito
Alcohol use, both short-term intoxication and longer-term use, is a notable risk factor for suicide. Despite the strong relationship between alcohol use and suicidal thoughts and behaviors, providers typically treat these two problems independently. In particular, acute psychiatric care hospitalizations for adolescents are typically brief, and many only cursorily address alcohol use. Integrating a brief motivational enhancement intervention for alcohol use into an inpatient psychiatric hospitalization treatment protocol has the potential to enhance motivation to stop or reduce drinking if adolescents can more fully understand how it increases risk for suicidal behavior...
November 2018: Journal of Substance Abuse Treatment
F Rice, L Riglin, T Lomax, E Souter, R Potter, D J Smith, A K Thapar, A Thapar
BACKGROUND: Depression is the leading global cause of disability and often begins in adolescence. The genetic architecture and treatment response profiles for adults and adolescents differ even though identical criteria are used to diagnose depression across different age groups. There is no clear consensus on how these groups differ in their symptom profiles. METHODS: Using data from a two-generation family study, we compared the presentation of DSM-IV depressive symptoms in adolescents and adults with MDD (Major Depressive Disorder)...
September 11, 2018: Journal of Affective Disorders
Lindi Martin, Martin Kidd, Soraya Seedat
BACKGROUND: The effect of childhood maltreatment (CM) on neuropsychological performance is well established, but the effect of anxiety proneness (AP) on such performance has been underexplored. We assessed the predictive ability of CM and AP, and their interaction, in non-clinical adolescents, for a range of previously documented neuropsychological deficits. METHODS: Multiple linear regression models were used to assess the unique and combined influences of CM and AP on neuropsychological performance in 104 non-clinical adolescents, who underwent both neuropsychiatric and neuropsychological assessment...
September 11, 2018: Journal of Affective Disorders
Laura Palagini, Katharina Domschke, Francesco Benedetti, Russell G Foster, Katharina Wulff, Dieter Riemann
INTRODUCTION: Mood disorders are among the most prevalent and serious mental disorders and rank high among to the leading global burdens of disease. The developmental psychopathology framework can offer a life course perspective on them thus providing a basis for early prevention and intervention. Sleep disturbances, are considered risk factors for mood disorders across childhood, adolescence and adulthood. Assuming that sleep disturbances may play a pivotal role in the pathogenesis of mood disorders from a life course point of view, we reviewed the data on developmental pathways towards mood disorders in adult life in relation to sleep disturbances...
September 11, 2018: Journal of Affective Disorders
Peng Zou, Lei Sun, Wang Yang, Yingfei Zeng, Qing Chen, Huan Yang, Niya Zhou, Guowei Zhang, Jinyi Liu, Ying Li, Lin Ao, Jia Cao
The aims of this study were to explore the associations between negative life events and anxiety, depressive, and stress symptoms among male senior college students who experience negative life events in daily life. Data were obtained from 582 male senior college students recruited from universities in Chongqing China. Participants completed the Adolescent Self-rating Life Events Checklist (ASLEC), and the Depression, Anxiety, and Stress Scale-21 (DASS-21). Socio-demographic information, lifestyle information, and a blood sample were acquired...
September 13, 2018: Psychiatry Research
Umberto Albert, Simona Tomassi, Giuseppe Maina, Sarah Tosato
Despite the growing interest in the prodromes of psychosis, the proper identification of those Ultra High Risk (UHR) subjects who will convert to psychosis remains an unresolved issue. It remains to be fully understood whether the risk of transition to psychosis is incremented by the concomitant presence of non-psychotic symptoms. We performed a systematic review in order to estimate: prevalence rates of non-psychotic disorders in UHR individuals and whether any comorbid disorder impacts on the risk of transition to frank psychosis...
September 15, 2018: Psychiatry Research
Hollis C Karoly, Joseph P Schacht, Lindsay R Meredith, Joanna Jacobus, Susan F Tapert, Kevin M Gray, Lindsay M Squeglia
OBJECTIVE: Adult and adolescent studies suggest increased motivational responses to cannabis cues among regular cannabis users. However, functional magnetic resonance imaging (fMRI) studies have not explored neural activation in response to visual cannabis cues among adolescents in the United States. Gaining a better understanding of the neural circuits related to cue-elicited craving during adolescence may shed light on the neural basis for the development of problematic cannabis use that could ultimately be targeted for interventions...
September 11, 2018: Addictive Behaviors
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