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https://www.readbyqxmd.com/read/28944608/coexistence-of-mutations-in-keratin-10-krt10-and-the-mitochondrial-genome-in-a-patient-with-ichthyosis-with-confetti-and-leber-s-hereditary-optic-neuropathy
#1
Agnieszka Kalinska-Bienias, Agnieszka Pollak, Cezary Kowalewski, Urszula Lechowicz, Piotr Stawinski, Aleksandra Gergont, Joanna Kosinska, Ewa Pronicka, Pawel Kowalski, Katarzyna Wozniak, Rafal Ploski
Ichthyosis with confetti (IWC) is a severe congenital genodermatosis characterized by ichthyosiform erythroderma since birth and confetti-like spots of normal skin appearing in childhood as a results of revertant mosaicism. This disorder is caused by mutations in KRT10 or KRT1 genes. We report a 16-year-old boy who presented ichthyosiform erythroderma with severe desquamation since birth and gradually worsening psycho-neurological symptoms (mental retardation, ataxia, dystonia, hypoacusis). The patient conspicuously lacked typical confetti-like spots at the age of 16...
September 25, 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/28944553/outcomes-for-bipolar-patients-assessed-in-the-french-expert-center-network-a-2-year-follow-up-observational-study-fondamental-advanced-centers-of-expertise-for-bipolar-disorder-face-bd
#2
Chantal Henry, Ophelia Godin, Philippe Courtet, Jean-Michel Azorin, Sébastien Gard, Frank Bellivier, Mircea Polosan, Jean-Pierre Kahn, Paul Roux, Valerie Aubin, Dominique Costagliola, Marion Leboyer, Bruno Etain
OBJECTIVE: A new health care system for patients with bipolar disorders was established in France under the auspices of Fondation FondaMental, based on thorough clinical assessment of patients and on close collaborations between expert centers and referring practitioners. We report the results of outcomes after 2 years of observational follow-up of adult patients assessed within the network. METHOD: A total of 984 patients were included in the study. We compared several parameters (e...
September 12, 2017: Bipolar Disorders
https://www.readbyqxmd.com/read/28944055/understanding-the-links-between-resilience-and-type-2-diabetes-self-management-a-qualitative-study-in-south-australia
#3
A L Wilson, D McNaughton, S B Meyer, P R Ward
BACKGROUND: Research conducted by Ward, Muller, Tsourtos, et al. (Soc Sci Med 72(7):1140-1148, 2011) has led to the development of the psycho-social interactive model of resilience, which reveals the interaction between individual resilience factors (i.e. coping, confidence and self esteem) and external resilience environments (i.e. employment, supportive family environments and health promoting policies) in facilitating the development of resilience. This present study explored the utility of this model of resilience for understanding how people self-manage type-2 diabetes...
2017: Archives of Public Health, Archives Belges de Santé Publique
https://www.readbyqxmd.com/read/28940942/is-lower-symptom-recognition-associated-with-socioeconomic-inequalities-in-help-seeking-for-potential-breast-cancer-symptoms
#4
Hilary Davies, Afrodita Marcu, Peter Vedsted, Katriina L Whitaker
OBJECTIVE: Socioeconomic inequalities in recognising signs and symptoms of cancer may result in inequalities in timely help-seeking and subsequent prognosis of breast cancer. We explored the mediating role of symptom attribution and concern on the relationship between level of education and help-seeking for potential breast cancer symptoms. METHODS: Women aged ≥47 years (n=961) were purposively recruited (by education) to complete an online vignette-based survey that included nipple rash and axillary lump (in separate vignettes) as potential symptoms of breast cancer...
September 20, 2017: Psycho-oncology
https://www.readbyqxmd.com/read/28937311/it-s-not-as-bad-as-you-think-menopausal-representations-are-more-positive-in-postmenopausal-women
#5
Lydia Brown, Valerie Brown, Fiona Judd, Christina Bryant
INTRODUCTION: The menopausal transition is associated with underlying hormonal changes that can contribute to a range of physical and emotional symptoms. Psycho-social factors including attitudes and internal representations play a central role in women's experience of the menopause, but very little is known about how representations might differ across menopausal stages. METHODS: A sample of 387 women aged 40-60 completed a postal questionnaire that included the menopausal representations questionnaire, the emotional representation subscale adapted from the illness perception questionnaire, and data on menopausal status...
September 22, 2017: Journal of Psychosomatic Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28937233/new-perspectives-in-the-model-of-stress-response
#6
I Tonhajzerova, M Mestanik
The reactions of human organism to changes of internal or external environment termed as stress response have been at the center of interest during recent decades. Several theories were designed to describe the regulatory mechanisms which maintain the stability of vital physiological functions under conditions of threat or other environmental challenges. However, most of the models of stress reactivity were focused on specific aspects of the regulatory outcomes - physiological (e.g. neuroendocrine), psychological or behavioral regulation...
September 22, 2017: Physiological Research
https://www.readbyqxmd.com/read/28933101/-discussion-on-relevant-theories-of-qi-blood-shen-and-formula-implication-of-guan-xin-jing-capsule
#7
Rui-Ping Li, Guo-Hua Yu, Jun-Fang Li, Shi-Huan Tang
In the field of traditional Chinese medicine(TCM),the definition of "Shen" contains a broad concept and a narrow concept. Broad "Shen" is the dominator and administrator of human vital movement,while narrow "Shen" means spirit, consciousness, thinking and emotions of human. "Shen" originates from innate essence of parents, and survives on acquired essence of water and food as well as the nutrition of its metaplastic Qi-Blood-Body fluid. Qi-Blood,the most precious asset of human body, is a quite important section of one person and the central material basis of "Shen-Zhi"...
November 2016: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/28932258/the-effect-for-japanese-workers-of-a-self-help-computerized-cognitive-behaviour-therapy-program-with-a-supplement-soft-drink
#8
Kentaro Shirotsuki, Yuji Nonaka, Keiichi Abe, So-Ichiro Adachi, Shohei Adachi, Tomifusa Kuboki, Mutsuhiro Nakao
BACKGROUND: Computerized cognitive behaviour therapy (CCBT) programs can provide a useful self-help approach to the treatment of psychological problems. Previous studies have shown that CCBT has moderate effects on depression, insomnia, and anxiety. The present study investigated whether a supplement drink that includes L-carnosine enhances the effect of CCBT on psychological well-being. METHODS: Eighty-seven participants were randomly allocated to a control group, CCBT, or CCBT with supplement drink...
2017: BioPsychoSocial Medicine
https://www.readbyqxmd.com/read/28931925/a-single-question-regarding-mobility-in-the-world-health-organization-quality-of-life-questionnaire-predicts-3-year-mortality-in-patients-receiving-chronic-hemodialysis
#9
Hsiu-Ho Wang, Miao-Chun Ho, Kuan-Yu Hung, Hui-Teng Cheng
Low quality of life, depression and poor quality of sleep are associated with increased mortality in hemodialysis patients. It is not clear which factor has the highest predictive power and what the core element is to explain the predictability. We thus conducted a prospective cohort study that included 151 hemodialysis adults. Three traits of interest were assessed by World Health Organization Quality of Life questionnaire, an abbreviated version (WHOQOL-BREF), Taiwanese Depression Questionnaire, and Athens Insomnia Scale, respectively...
September 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28931101/-the-early-recognition-of-mental-morbidities-during-psycho-oncologic-treatment
#10
Mónika Mailáth, Réka Laczkóné Majer, Zsolt Horváth, Sándor Gergely Szabó
Unfortunately there have been no positive changes in the main indicators of cancer incidence in Hungarian population since the turn of the millennium. The main goal of psycho-oncologic treatment is to provide the highest possible quality of life to the patient. The prevalence of mental disorders in cancer patients is high and it is accompanied by a rather small number of qualified staff. Thus, the remedy might be the identification of high-risk patients, i.e. the systematic psycho-oncologic screening. Hungary is still lacking a unified screening method that involves all oncologic treatment-providing units...
September 20, 2017: Magyar Onkologia
https://www.readbyqxmd.com/read/28929802/a-study-of-outcomes-of-patients-treated-at-a-uk-major-trauma-centre-for-moderate-or-severe-injuries-one-to-three-years-after-injury
#11
Stephen Spreadborough, Kate Radford, Roshan das Nair, Adam Brooks, Miriam Duffy
OBJECTIVE: To assess return to work outcomes of major trauma patients treated at a level 1 UK major trauma centre and evaluate factors associated with improved outcomes. DESIGN: Cross-sectional cohort design. SUBJECTS: In total, 99 patients at one, two or three years post-discharge from a Major Trauma Centre with an injury severity score above 9, in full-time work or education prior to injury, aged 18-70 and discharged between April 2012 and June 2015...
September 1, 2017: Clinical Rehabilitation
https://www.readbyqxmd.com/read/28926147/do-universal-school-based-mental-health-promotion-programmes-improve-the-mental-health-and-emotional-well-being-of-young-people-a-literature-review
#12
REVIEW
C A O'connor, J Dyson, F Cowdell, R Watson
AIM: To examine evidence-using a range of outcomes- for the effectiveness of school-based mental health and emotional well-being programmes. BACKGROUND: It is estimated that 20% of young people experience mental health difficulties every year. Schools have been identified as an appropriate setting for providing mental health and emotional well-being promotion prompting the need to determine whether current school-based programmes are effective in improving the mental health and emotional well-being of young people...
September 19, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28925573/achieving-recovery-in-patients-with-schizophrenia-through-psycho-social-interventions-a-retrospective-study
#13
Mariachiara Buonocore, Marta Bosia, Maria Alice Baraldi, Margherita Bechi, Marco Spangaro, Federica Cocchi, Laura Bianchi, Carmelo Guglielmino, Antonella Rita Mastromatteo, Roberto Cavallaro
AIM: Recovery, or functional remission represents the ultimate treatment goal in schizophrenia. Despite its importance, a standardized definition of remission is still lacking, thus reported rates significantly vary across studies. Moreover, the effects of rehabilitative interventions on recovery are still poorly investigated. This study aims to evaluate recovery in a sample of patients with chronic schizophrenia engaged in rehabilitation programs and to explore contributing factors, with a focus on of socio-cognitive rehabilitative interventions...
September 19, 2017: Psychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/28924689/future-research-in-psycho-oncology
#14
Ute Goerling, Anja Mehnert
Since the mid-1970s psycho-oncology and psycho-oncological research have been systematically developed in many industrialized countries and have produced nationally and internationally accepted guidelines. In this article developments and challenges are presented and discussed. From the perspective of various oncological treatment options, different needs for further psycho-oncological research are considered.
2018: Recent Results in Cancer Research
https://www.readbyqxmd.com/read/28924682/rehabilitation-for-cancer-patients
#15
Joachim Weis, Jürgen M Giesler
Rehabilitation for cancer patients aims at reducing the impact of disabling and limiting conditions resulting from cancer and its treatment in order to enable patients to regain social integration and participation. Given current trends in cancer incidence and survival along with progress in medical treatment, cancer rehabilitation is becoming increasingly important in contemporary health care. Although not without limitations, the International Classification of Functioning, Disability and Health (ICF) provides a valuable perspective for cancer rehabilitation in understanding impairments in functioning and activity as the result of an interaction between a health condition and contextual factors...
2018: Recent Results in Cancer Research
https://www.readbyqxmd.com/read/28924680/the-oncological-patient-in-the-palliative-situation
#16
Steffen Eychmueller, Diana Zwahlen, Monica Fliedner
Palliative care approaches patients and their suffering with a bio-psycho-social-spiritual model. Thus, it is the strength of palliative care to complement the diagnosis driven approach of medical cancer care by a problem and resources-based assessment, participatory care plan and person-directed interventions. Interventions need to reflect timely prognosis, target population (the patient, the family carer, the professional) and level of trust and remaining energy. In palliative care the relevance of psycho-oncological aspects in the care of the terminally ill is considerable in the understanding of the overall suffering of patients approaching death and their loved ones and in their care and support...
2018: Recent Results in Cancer Research
https://www.readbyqxmd.com/read/28924679/psycho-oncology-a-patient-s-view
#17
Patricia Garcia-Prieto
Culturally the most important, valued, and less stigmatized part of cancer care is the medical part: The surgeon cutting the tumors out and the oncologist leading the strategic decision-making of the medical treatments available. The least valued and stigmatized part of cancer remains the psychosocial care. This chapter describes-through the eyes of an academic, psychologist, stage IV melanoma patient, and patient advocate-how one patient navigated changing psycho-oncological needs from early stage-to-stage IV through a whole range of psychological interventions available...
2018: Recent Results in Cancer Research
https://www.readbyqxmd.com/read/28924678/gender-opportunities-in-psychosocial-oncology
#18
Matthew Loscalzo, Karen Clark
So much has happened since the original publication of this chapter. In some ways, the progress made in appreciating the full spectrum of sexual and gender expression has been uneven and in some nations, there has been serious regression and resulting repression. But overall, especially in the industrialized countries, there is much greater awareness of sex and gender and its importance in health and well being. In this updated chapter, we put sex and gender into a historical context that is relevant to psycho-oncology and that openly accepts that society overall, is highly conflicted when it comes to how women and men get the best out of each other, never mind how to best integrate lesbian, gay, bisexual, and transgender (LGBT) communities...
2018: Recent Results in Cancer Research
https://www.readbyqxmd.com/read/28924676/psychosocial-impact-of-cancer
#19
Susanne Singer
Diagnosis and treatment of malignant diseases affect in many ways the lives of patients, relatives and friends. Common reactions immediately after the diagnosis are shock and denial, frequently followed by depression, anxiety and/or anger. About a third of all cancer patients suffer from a co-morbid mental health condition, requiring professional support by the entire medical team, including psycho-oncologists. Often overlooked issues are financial and social problems due to inability to work or due to out-of-pocket costs for the medical treatment...
2018: Recent Results in Cancer Research
https://www.readbyqxmd.com/read/28923784/assessment-of-quality-of-life-on-4-year-growth-hormone-therapy-in-japanese-patients-with-adult-growth-hormone-deficiency-a-post-marketing-multicenter-observational-study
#20
Hitoshi Ishii, Akira Shimatsu, Hiromi Nishinaga, Osamu Murai, Kazuo Chihara
OBJECTIVE: Improvement of quality of life (QOL) by growth hormone (GH) therapy was not demonstrated in Japanese adult growth hormone deficiency (AGHD) patients by either the QOL Assessment of Growth Hormone Deficiency in Adults or the Questions on Life Satisfaction-Hypopituitarism, which are widely used to evaluate QOL in Western AGHD patients. We therefore evaluated QOL in Japanese AGHD patients receiving recombinant GH, Norditropin® (Novo Nordisk A/S, Denmark), using the newly developed Adult Hypopituitarism Questionnaire (AHQ)...
September 1, 2017: Growth Hormone & IGF Research
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