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https://www.readbyqxmd.com/read/28724260/pleuropterus-multiflorus-hasuo-mediated-straightforward-eco-friendly-synthesis-of-silver-gold-nanoparticles-and-evaluation-of-their-anti-cancer-activity-on-a549-lung-cancer-cell-line
#1
Verónica Castro-Aceituno, Ragavendran Abbai, Seong Soo Moon, Sungeun Ahn, Ramya Mathiyalagan, Yu-Jin Kim, Yeon-Ju Kim, Deok Chun Yang
Pleuropterus multiflorus (Hasuo) is a widely used medicinal plant in Korea and China for treating amnesia, isnomia, heart throbbing etc. With the constructive idea of promoting the wide-spread usage of P. multiflorus, we propose its indirect usage in the form of biologically active silver (Pm-AgNPs) and gold nanoparticles (Pm-AuNPs). The synthesized nanoparticles were predominantly spherical, crystalline with the Z-average hydrodynamic diameter of 274.8nm and 104.8nm respectively. Also, proteins and phenols were identified as the major players involved in their synthesis and stability...
July 15, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28724233/examining-the-impact-of-active-clearance-of-chest-drainage-catheters-on-postoperative-atrial-fibrillation
#2
Samuel St-Onge, Walid Ben Ali, Ismail Bouhout, Denis Bouchard, Yoan Lamarche, Louis P Perrault, Philippe Demers
OBJECTIVE: Postoperative atrial fibrillation (POAF) is one of the most frequent complications encountered after heart surgery, and significantly increases complications and mortality. An obstructed chest tube, leaving unevacuated blood around the heart and lungs, can lead to atrial inflammation, which can trigger POAF. The aim of this study was to assess the effectiveness of chest drainage incorporating an active tube clearance (ATC) system in reducing the rate of POAF. METHODS: This retrospective analysis based on 300 consecutive patients undergoing heart surgery compared 142 patients allocated to an ATC drainage protocol with 158 controls managed with standard chest drainage...
August 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28724221/impact-of-the-nsaid-diclofenac-on-survival-development-behaviour-and-health-of-embryonic-and-juvenile-stages-of-brown-trout-salmo-trutta-f-fario
#3
Simon Schwarz, Hannah Schmieg, Marco Scheurer, Heinz-R Köhler, Rita Triebskorn
The NSAID diclofenac is controversially discussed with respect to its environmental relevance. Since further information is need to assess whether diclofenac should be included as substance of priority in the EU water framework directive, we investigated the impact of this analgesic on the embryonic development of brown trout (Salmo trutta f. fario) from fertilized egg until the end of sac-fry stage and studied effects in juvenile fish six months post hatch. Embryos were exposed to five test concentrations (0...
July 14, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28724135/i-do-not-have-heart-disease-should-i-be-taking-aspirin
#4
Kunal N Karmali, Mark D Huffman
No abstract text is available yet for this article.
July 1, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/28724134/association-of-implantable-cardioverter-defibrillators-with-survival-in-patients-with-and-without-improved-ejection-fraction-secondary-analysis-of-the-sudden-cardiac-death-in-heart-failure-trial
#5
Selcuk Adabag, Kristen K Patton, Alfred E Buxton, Thomas S Rector, Kristine E Ensrud, Kairav Vakil, Wayne C Levy, Jeanne E Poole
Importance: Improvement in left ventricular ejection fraction (EF) to >35% occurs in many patients with reduced EF at baseline. To our knowledge, whether implantable cardioverter defibrillator (ICD) therapy improves survival for these patients is unknown. Objective: To examine the efficacy of ICD therapy in reducing risk of all-cause mortality and sudden cardiac death among patients with an EF ≤35% at baseline, with or without an improvement in EF to >35% during follow-up...
July 1, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/28724040/cardiac-remodeling-indicators-in-adolescent-athletes
#6
Joaquim Castanheira, João Valente-Dos-Santos, Daniela Costa, Diogo Martinho, Jorge Fernandes, João Duarte, Nuno Sousa, Vasco Vaz, Luis Rama, António Figueiredo, Manuel Coelho-E-Silva
Objective: The idea that different sports and physical training type results in different cardiac adaptations has been widely accepted. However, this remodelling process among different sport modalities is still not fully understood. Thus, the current study aims to investigate the heart morphology variation associated with a set of different modalities characterized by distinct models of preparation and different methods and demands of training and completion. Method: The sample comprises 42 basketball players, 73 roller hockey players, 28 judo athletes and 21 swimmers...
May 2017: Revista da Associação Médica Brasileira
https://www.readbyqxmd.com/read/28723905/evolution-of-anti-trypanosoma-cruzi-antibody-production-in-patients-with-chronic-chagas-disease-correlation-between-antibody-titers-and-development-of-cardiac-disease-severity
#7
Ingebourg Georg, Alejandro Marcel Hasslocher-Moreno, Sergio Salles Xavier, Marcelo Teixeira de Holanda, Eric Henrique Roma, Maria da Gloria Bonecini-Almeida
Chagas disease is one of the most important endemic infections in Latin America affecting around 6-7 million people. About 30-50% of patients develop the cardiac form of the disease, which can lead to severe cardiac dysfunction and death. In this scenario, the identification of immunological markers of disease progression would be a valuable tool for early treatment and reduction of death rates. In this observational study, the production of anti-Trypanosoma cruzi antibodies through a retrospective longitudinal follow-up in chronic Chagas disease patients´ cohort and its correlation with disease progression and heart commitment was evaluated...
July 19, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28723882/altered-carnitine-homeostasis-in-children-with-increased-pulmonary-blood-flow-due-to-ventricular-septal-defects
#8
Stephen M Black, Aida Field-Ridley, Shruti Sharma, Sanjiv Kumar, Roberta L Keller, Rebecca Kameny, Emin Maltepe, Sanjeev A Datar, Jeffrey R Fineman
OBJECTIVES: Congenital heart disease with increased pulmonary blood flow results in progressive pulmonary vascular endothelial dysfunction and associated increased perioperative morbidity. Using our ovine model of congenital heart disease with increased pulmonary blood flow, we have previously demonstrated progressive endothelial dysfunction associated with disruption in carnitine homeostasis, mitochondrial dysfunction, decreased nitric oxide signaling, and enhanced reactive oxygen species generation...
July 18, 2017: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/28723836/subjective-versus-objective-estimated-cardiovascular-disease-risk-and-adherence-to-physical-activity-in-african-american-women
#9
Nadia Robinson, Arlene Miller, JoEllen Wilbur, Louis Fogg
BACKGROUND: Cardiovascular disease (CVD) is the leading cause of death for African American (AA) women in the United States. Despite high prevalence of CVD risk factors, AA women perceive their CVD risk as low. OBJECTIVE: Our objectives were to (1) identify relationships between subjective (self-reported perceived) CVD risk and objective CVD risk estimated by the American College of Cardiology/American Heart Association atherosclerotic CVD (ASCVD) risk estimator, (2) identify demographic and psychosocial factors associated with subjective perceived risk and discrepancy with objective estimated CVD risk, and (3) determine whether subjective perceived CVD risk was associated with physical activity (PA) adherence...
July 18, 2017: Journal of Cardiovascular Nursing
https://www.readbyqxmd.com/read/28723834/talking-with-a-doctor-during-a-visit-elicits-increases-in-systolic-and-diastolic-blood-pressure
#10
Wenqiang Qi, Qinghua Wu, Yanqing Wu, Qiang Peng, Ping Li, Xiaoshu Cheng, Hai Su
OBJECTIVE: To investigate the impact of talking with doctors on blood pressure (BP) in outpatients. PATIENTS AND METHODS: This study included 122 hypertensive and 78 normotensive outpatients. BP was measured initially in silence with oscillometric BP monitors three times at 1-min intervals as follows: pre-1, pre-2, and pre-3. BP was then measured with the same device immediately, at 3 min, and at 5 min after talking commenced as follows: during-1, during-3, and during-5...
July 18, 2017: Blood Pressure Monitoring
https://www.readbyqxmd.com/read/28723813/effect-of-resistance-training-on-blood-pressure-and-autonomic-responses-in-treated-hypertensives
#11
Gabriela Alves Trevizani, Mariana Balbi Seixas, Paulo Roberto Benchimol-Barbosa, Jeferson Macedo Vianna, Lilian Pinto da Silva, Jurandir Nadal
This study evaluated the effect of resistance training (RT) on heart rate variability (HRV) and on blood pressure (BP) responses to acute and short-term exposure in treated hypertensive subjects. Twenty one men participated in the study, eight hypertensive under drug treatment regimen and achieving adequate blood pressure control prior to inclusion (HT) and thirteen normotensive (NT). The RT protocol consisted of 12 sessions with 8 exercises (leg extension, leg press, leg curl, bench press, seated row, triceps push-down, seated calf flexion and seated arm curl) performed for 2 sets of 15-20 repetitions with 50% of one repetition-maximum (1RM) with 2-minute rest intervals in between sets, 3x/week...
July 17, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28723794/thrombosis-and-antiphospholipid-antibody-syndrome-during-acute-q-fever-a-cross-sectional-study
#12
Matthieu Million, Nathalie Bardin, Simon Bessis, Nadia Nouiakh, Charlaine Douliery, Sophie Edouard, Emmanouil Angelakis, Annick Bosseray, Olivier Epaulard, Stéphanie Branger, Bernard Chaudier, Karine Blanc-Laserre, Nicole Ferreira-Maldent, Elisa Demonchy, France Roblot, Jacques Reynes, Felix Djossou, Camelia Protopopescu, Patrizia Carrieri, Laurence Camoin-Jau, Jean-Louis Mege, Didier Raoult
Q fever is a neglected and potentially fatal disease. During acute Q fever, antiphospholipid antibodies are very prevalent and have been associated with fever, thrombocytopenia, acquired heart valve disease, and progression to chronic endocarditis. However, thrombosis, the main clinical criterion of the 2006 updated classification of the antiphospholipid syndrome, has not been assessed in this context. To test whether thrombosis is associated with antiphospholipid antibodies and whether the criteria for antiphospholipid syndrome can be met in patients with acute Q fever, we conducted a cross-sectional study at the French National Referral Center for Q fever...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28723765/perioperative-management-of-intracardiac-leiomyomatosis-an-observational-cohort-study
#13
Jiaying Xu, Min Wei, Qi Miao, Bin Zhu, Chunhua Yu, Yuguang Huang
Intracardiac leiomyomatosis (ICLM) is a rare condition in which the benign tumor extends into the right heart chambers through inferior vena cava. The best surgical approach still remains unclear.We present a retrospective cohort of 36 patients diagnosed with ICLM in Peking Union Medical College Hospital between 2002 and 2016.The mean patient age was 44.5 (range 25-55) years. The clinical manifestations were various, including shortness of breath, chest tightness, edema of the lower extremities, palpitations, syncope, etc...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28723732/role-of-anesthesia-in-endovascular-stroke-therapy
#14
Arthur Wang, Apolonia E Abramowicz
PURPOSE OF REVIEW: Recent randomized clinical trials have demonstrated strong efficacy of endovascular therapy (EVT) for acute ischemic stroke (AIS) from large vessel occlusions; in the USA alone, tens of thousands of patients annually may benefit. The impact of the type of anesthesia used during mechanical thrombectomy on patient outcomes remains controversial. This review discusses the current literature on the effects of anesthesia type on patient outcome following endovascular stroke therapy...
July 18, 2017: Current Opinion in Anaesthesiology
https://www.readbyqxmd.com/read/28723590/cardioprotective-mitochondrial-binding-by-hexokinase-i-is-induced-by-a-hyperoxic-acute-thermal-insult-in-the-rainbow-trout-oncorhynchus-mykiss
#15
Neal Ingraham Callaghan, Kenneth Javier Williams, Tyson James MacCormack
Due to the substantial photosynthetic biomass in their habitat, salmonids such as the rainbow trout (Oncorhynchus mykiss) can be subject to hyperoxia in addition to high temperatures associated with climate change. Both stressful conditions increase the incidence of damaging reactive oxygen species (ROS). The mitochondrial association of hexokinase has been shown to increase in the hearts of certain fish experiencing hypoxia in a putative cardioprotective response to oxidative stress. In this study, the mitochondrial association of hexokinase I (HKI) and markers of oxidative damage and metabolic stress were probed to elucidate the cardioprotective role of hexokinase in the rainbow trout...
July 16, 2017: Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology
https://www.readbyqxmd.com/read/28723347/heart-rate-variability-is-enhanced-by-long-lasting-pleasant-touch-at-ct-optimized-velocity
#16
Chantal Triscoli, Ilona Croy, Susann Steudte-Schmiedgen, Håkan Olausson, Uta Sailer
INTRODUCTION: The present study explores whether long-lasting pleasant touch has positive effects on the stress response, reward sensitivity, mood, and interoceptive awareness. METHODS: 40 participants received either 35minutes of brush stroking targeting C-tactile fibres (CT) or vibration on the forearm, and rated pleasantness and intensity. Prior and after, stress response (cortisol and heart rate variability), reward sensitivity, mood and interoceptive awareness were measured...
July 16, 2017: Biological Psychology
https://www.readbyqxmd.com/read/28722567/bartonella-infection-in-hematophagous-insectivorous-and-phytophagous-bat-populations-of-central-mexico-and-the-yucatan-peninsula
#17
Matthew J Stuckey, Bruno B Chomel, Guillermo Galvez-Romero, José Ignacio Olave-Leyva, Cirani Obregón-Morales, Hayde Moreno-Sandoval, Nidia Aréchiga-Ceballos, Mónica Salas-Rojas, Alvaro Aguilar-Setién
Although emerging nonviral pathogens remain relatively understudied in bat populations, there is an increasing focus on identifying bat-associated bartonellae around the world. Many novel Bartonella strains have been described from both bats and their arthropod ectoparasites, including Bartonella mayotimonensis, a zoonotic agent of human endocarditis. This cross-sectional study was designed to describe novel Bartonella strains isolated from bats sampled in Mexico and evaluate factors potentially associated with infection...
June 12, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28722488/berberine-promotes-ischemia-induced-angiogenesis-in-mice-heart-via-upregulation-of-microrna-29b
#18
Mo-Li Zhu, Ya-Ling Yin, Song Ping, Hai-Ya Yu, Guang-Rui Wan, Xu Jian, Peng Li
BACKGROUND: Berberine has several preventive effects on cardiovascular diseases. Increased expression of miR-29b has been reported to attenuate cardiac remodeling after myocardial infarction (MI). We hypothesized that berberine via an miR-29b-dependent mechanism promotes angiogenesis and improves heart functions in mice after MI. METHODS: The MI model was established in mice by ligation of left anterior descending coronary artery. The expression of miR-29b was examined by RT-qPCR...
July 19, 2017: Clinical and Experimental Hypertension: CHE
https://www.readbyqxmd.com/read/28722335/protective-effects-of-folic-acid-on-pm2-5-induced-cardiac-developmental-toxicity-in-zebrafish-embryos-by-targeting-ahr-and-wnt-%C3%AE-catenin-signal-pathways
#19
Cong Yue, Cheng Ji, Hang Zhang, Leshuai W Zhang, Jian Tong, Yan Jiang, Tao Chen
Our previous observations indicated that extractable organic matter (EOM) from PM2.5 induced malformations in the heart of zebrafish embryos by activating AhR and inhibiting canonical Wnt/β-catenin signal pathway. As a nutritional factor, folic acid (FA) is reported to prevent cardiac defects during embryo development. Hence, we hypothesize that FA may prevent PM2.5-induced heart defects by interfering with AhR and Wnt/β-catenin signaling pathways. Our results showed that FA supplementation alleviated the EOM-induced heart defects in zebrafish embryos, and both AhR inhibitor CH223191 and Wnt activator CHIR99021 enhanced the protective efficiency of FA...
July 19, 2017: Environmental Toxicology
https://www.readbyqxmd.com/read/28722286/fighting-fungus-with-a-laser-and-a-hose-management-of-a-giant-candida-albicans-implantable-cardioverter-defibrillator-lead-vegetation-with-simultaneous-angiovac-aspiration-and-laser-sheath-lead-extraction
#20
Brandon M Jones, Oussama Wazni, Susan J Rehm, Mehdi H Shishehbor
Infections involving internal cardiac devices can be very challenging to treat, and almost universally require complete device extraction for successful management. Of the pathogens that cause device-related endocarditis, fungi such as Candida albicans are notoriously difficult to manage because of their propensity to produce large vegetations and the need for long-term treatment with potentially toxic medications. Furthermore, individuals who develop fungal, device-associated endocarditis are typically among the most complex patients, with significant comorbidities that place them at high risk for open heart procedures such as surgical device extraction...
July 19, 2017: Catheterization and Cardiovascular Interventions
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