Amin H Nassar, Edward El-Am, Ryan Denu, Sarah Abou Alaiwi, Talal El Zarif, Walid Macaron, Noha Abdel-Wahab, Aakash Desai, Caleb Smith, Kaushal Parikh, Muhannad Abbasi, Elias Bou Farhat, James M Williams, Jeremy D Collins, Ahmad Al-Hader, Rana R McKay, Carmel Malvar, Mohamad Sabra, Caiwei Zhong, Raquelle El Alam, Omar Chehab, Joao Lima, Minh Phan, Hanna Ferreira Dalla Pria, Alexandra Trevino, Tomas G Neilan, Jennifer M Kwan, Vinod Ravi, Hari Deshpande, George Demetri, Toni K Choueiri, Abdul Rafeh Naqash
BACKGROUND: Primary cardiac soft tissue sarcomas (CSTS) affect young adults, with dismal outcomes. OBJECTIVES: The aim of this study was to investigate the clinical outcomes of patients with CSTS receiving immune checkpoint inhibitors (ICIs). METHODS: A retrospective, multi-institutional cohort study was conducted among patients with CSTS between 2015 and 2022. The patients were treated with ICI-based regimens. The Kaplan-Meier method was used to estimate overall survival (OS) and progression-free survival (PFS)...
February 2024: JACC CardioOncology