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Integrative Medicine Research

Kyung Eun Lee, Joong Jae Kim, Hee-Jeong Jin, Siwoo Lee, Eun Bo Shim
[This corrects the article DOI: 10.1016/j.imr.2017.01.005.].
March 2018: Integrative Medicine Research
Keisou Ishimaru, Takuma Nakajima, Yoshihisa Namiki, Kenji Ryotokuji
Background: We previously reported that pinpoint plantar long-wavelength infrared light irradiation (stress-free therapy; SFT) is useful for alleviating insulin resistance and improving intracranial blood flow in patients with type 2 diabetes mellitus. This study was undertaken to evaluate the influences of SFT on chorioretinal hemodynamics (retinal artery and vein blood flows) as well as atherosclerosis-related factors (TG, LDL-C) and VEGF in patients with dyslipidemia. Methods: Four patients with dyslipidemia received 15-minute irradiation with a stress-free apparatus (far-infrared wavelength, 30 mW)...
March 2018: Integrative Medicine Research
Bok-Nam Seo, Ji-Eun Park, Young-Eun Kim, Kyung-Won Kang, In-Chan Seol, Sun-Mi Choi
Background: Hypertension is a major cause of cardiovascular disease and associated mortality, and postmenopausal women are at a high risk of hypertension. We aim to investigate the hypotensive effect and safety of acupuncture, focusing on postmenopausal women with prehypertension and stage 1 hypertension. In addition, we aim to investigate whether the effect of acupuncture treatment differed, depending on Sasang Constitution and cold-heat pattern. Methods: This study is designed as an intervention cohort study...
March 2018: Integrative Medicine Research
Harith Jameel Mahdi, Nurzalina Abdul Karim Khan, Mohd Zaini Bin Asmawi, Roziahanim Mahmud, Vikneswaran A/L Murugaiyah
Background: The medicinal uses of plants are in many cases based exclusively on traditional knowledge without enough scientific evidences. Different parts of Moringa oleifera were traditionally used for the treatment of wide variety of ailments including arthritis and joints pain. The present study had been designed to evaluate the anti-arthritic and anti-nociceptive activities of ethanol extract of Moringa leaves, this being the most abundant plant part suitable for commercial mass production of botanical medicinal products...
March 2018: Integrative Medicine Research
Bo Kyung Hwang, Yeo-Jin Yoon, Sang Yun Han, Soo Jin Lee, Han Chae
Background: The Yin-Yang is a pivotal concept of traditional East-Asian medicine, however the stability of Yin-Yang temperament in Sasang Personality Questionnaire (SPQ) over time has not been extensively studied. The purpose of this study was to examine the test-retest validity of SPQ with a large number of participants. Methods: SPQ test was conducted two times with three months interval in 247 Korean university students. The structural validity of first SPQ data was examined with Factor analysis and Cronbach's alpha, and the correlation between first and second measure of SPQ was attested with Pearson's correlation...
March 2018: Integrative Medicine Research
Jeongyun Lee, Sang Yun Han, Minwoo Hwang, Nayoung Bae, Han Chae
Background: The Sasang typology is a traditional Korean personalized medicine and its Cold-Heat subgroup identification is essential for effective use of medical herbs and acupuncture. The purpose of this study was to discover differences between Cold-Heat subgroups with objective clinical measures and to examine its clinical usefulness. Methods: The pathophysiological symptoms of the digestive system, temperament and body shape of 241 patients were measured using the Sasang Digestive Function Inventory (SDFI), Sasang Personality Questionnaire (SPQ) and Body Mass Index (BMI)...
March 2018: Integrative Medicine Research
Kwang-Ho Bae, Young-Seok Jeong, Ho-Yeon Go, Seung-Ho Sun, Tae-Hoon Kim, Ki-Yong Jung, Yun-Kyung Song, Seong-Gyu Ko, You-Kyung Choi, Jong-Hyeong Park, Siwoo Lee, Youngseop Lee, Chan-Yong Jeon
Background: Cold hypersensitivity in the hands and feet (CHHF) is a symptom patients usually feel cold in their hands and feet, but not dealt with a disease in western medicine. However, it is often appealed by patients at a clinic of Korean medicine (KM), considered to be a sort of key diagnostic indicator, and actively treated by physicians. Nevertheless, there is no standardized diagnostic definition for CHHF. Therefore, we surveyed KM experts' opinions to address the clinical definition, diagnostic criteria, and other relevant things on CHHF...
March 2018: Integrative Medicine Research
Enosakhare A Asemota, Ifeyinwa M Okafor, Henshaw U Okoroiwu, Ewaro R Ekong, Stanley Obialor Anyanwu, Esienanwan Esien Efiong, Francis Udomah
Background: Low concentration of trace elements has been associated with poor prognosis and mortality in HIV infection. Methods: A cross sectional study was conducted among 100 HIV-infected subjects (70 were on ART treatment, while 30 were ART naïve). Fifty (50) apparently healthy controls were enrolled. Concentration of serum levels of zinc and copper was done using atomic absorption spectrometric method, while complete blood count was determined using automated blood analyzer...
March 2018: Integrative Medicine Research
Abbass Ghanbari-Niaki, Ayoub Saeidi, Mehdi Ahmadian, Leila Gharahcholo, Nooshin Naghavi, Mohammad Fazelzadeh, Soleiman Mahjoub, Stephen Myers, Andrew Williams
Background: We examined the effect of antioxidant supplementation and exercise on irisin within postmenopausal women. Methods: Forty-eight participants (age: 55.7 ± 4.9 years; weight: 68.0 ± 6.3 kg; BMI 27.0 ± 2.7; mean ± SD) were randomized into four groups for the eight week intervention: control group (CG; n  = 12), resistance training group (RTG; n  = 12), supplementation with Zataria multiflora group (ZG; n  = 12), or supplementation with Z...
March 2018: Integrative Medicine Research
Deepika Singh, Prabir Kumar Chaudhuri
Cardiovascular diseases are the leading cause of death, accounting about 31% deaths globally in 2012. The major risk factors causing cardiovascular diseases are coronary atherosclerosis, hyperlipidemia, myocardial infarction, and stroke. The dominating cause of cardiovascular diseases is accredited to our modern lifestyle and diet. Medicinal plants have been used for the prevention and treatment of cardiovascular diseases from centuries. The in built chirality and chemical space of natural products have been playing an important role in providing leads and templates for pharmacophore synthesis...
March 2018: Integrative Medicine Research
Mohaddese Mahboubi
Sinusitis is associated with inflammation and infections of air-filled cavities of sinuses. The aim of this study was to evaluate the potential efficacy of Nigella sativa seed fixed oil in management of sinusitis. The information was extracted from accessible international databases, traditional books, electronic resources, and unpublished data. Results: The results of investigations on N. sativa seed fixed oil showed its therapeutic potential in treatment of sinusitis by its anti-inflammatory, antioxidant, antihistaminic, immune-modulator, antimicrobial and analgesic effects...
March 2018: Integrative Medicine Research
Manali Sughosh Upasani, Sughosh Vishweshwar Upasani, Vishal Gokul Beldar, Chetana Gokul Beldar, Pranjal P Gujarathi
Snakes have fascinated humankind for millennia. Snakebites are a serious medical, social, and economic problem that are experienced worldwide; however, they are most serious in tropical and subtropical countries. The reasons for this are 1) the presence of more species of the most dangerous snakes, 2) the inaccessibility of immediate medical treatment, and 3) poor health care. The goal of this study was to collect information concerning rare, less utilized, and less studied medicinal plants. More than 100 plants were found to have potential to be utilized as anti-snake venom across India...
March 2018: Integrative Medicine Research
Daniel J Cohen, Steven Schulman, Charles S Masarsky, Marion Todres-Masarsky
This review article proposes a model of integrative care for cardiovascular patients in institutional settings. We review relevant historic and contemporary examples of medical-chiropractic cooperation and a brief review of the literature illustrating the clinical benefits of chiropractic care for patients with cardiovascular disease. The groundwork proposes a distinct research and clinical practice model incorporating the doctor of chiropractic (D.C.) as a synergistic partner with the medical cardiologist coined the Kaleidoscope Model of Integrative Care (KM)...
March 2018: Integrative Medicine Research
SunKu Chung, Seongwon Cha, Seo-Young Lee, Jung-Hyun Park, Siwoo Lee
Everything in the surrounding universe can be attributed into five elements. Human organs can be also linked to the five elements. Cells, the smallest unit of the human body, consist of cellular organelles as little organs. Here, we extended the concept of the five elements to a cellular level via the human organs, theoretically re-evaluating the overall association of cellular organelles in maintaining the homeostasis of cellular functions.
December 2017: Integrative Medicine Research
Jeong Hwan Park, Soyoung Kim, Jae-Woo Park, Seok-Jae Ko, Sanghun Lee
Background: Functional dyspepsia (FD) is the seventh most common disease encountered in Korean medicine (KM) clinics. Despite the large number of FD patients visiting KM clinics, the accumulated medical records have no utility in evidence development, due to being unstructured. This study aimed to construct a standard operating procedure (SOP) with appropriate structured diagnostic methods for FD, and assess the feasibility for use in KM clinics. Methods: Two rounds of professional surveys were conducted by 10 Korean internal medicine professors to select the representative diagnostic methods...
December 2017: Integrative Medicine Research
Hyunil Ha, Ki-Shuk Shim, Jin Yeul Ma
Background: The hooks and stems of Uncaria sinensis have been used to mitigate cardiovascular and central nervous system disorders in Asia traditional medicine. Regulation of osteoclast differentiation and activity is a major target for preventing and treating pathological bone diseases. Methods: Tartrate-resistant acid phosphatase (TRAP) activity and the number of TRAP-stained multinucleated cells were used to examine receptor activator of nuclear factor-κB ligand (RANKL)-induced osteoclast differentiation...
December 2017: Integrative Medicine Research
Sungha Kim, Sanghun Lee, Won-Bae Ha, Jung-Han Lee, Hyun-Jong Jung, Hong-Min Chu, Seung-Bum Yang, Sunmi Choi, Mi Ju Son, Jae Hyo Kim, Youngju Jeon
Background: Acupuncture is a relatively safe, commonly used "alternative" medical treatment for various symptoms. However, adverse effects can occur, including trauma, pneumothorax, and central-nervous-system injury. Our objective was to develop a reliable and practical procedure for ultrasound imaging of acupuncture points to improve safety during needling, and to acquire ultrasound images of several (44) acupuncture points, especially those in high-risk areas, according to an in-house standard operating procedure...
December 2017: Integrative Medicine Research
Younghee Yun, Inhwa Choi
Background: There is a growing trend for patients to seek the least invasive treatments with less risk of complications and downtime for facial rejuvenation. Thread embedding acupuncture has become popular as a minimally invasive treatment. However, there is little clinical evidence in the literature regarding its effects. Methods: This single-arm, prospective, open-label study recruited participants who were women aged 40-59 years, with Glogau photoaging scale III-IV...
December 2017: Integrative Medicine Research
Miyoung Ahn, Eun-Ji Park, Jong-Min Woo
Background: Small- and medium-sized enterprises (SMEs) have played key roles in the economic growth and technical innovation of traditional and complementary and alternative medicine (T&CM). Research and development (R&D) are critical activities for industrial progress. This study aimed to characterize the current status of SME R&D activities and to explore manufacturers' perceptions of R&D expansion. Methods: Records of the distribution of T&CM SMEs and R&D resources detailed in the 2014 Statistics of Korea T&CM Industries survey, a previously conducted survey on the industrial status of the T&CM field, were reviewed...
December 2017: Integrative Medicine Research
Iksung Kim, Jinsoo Bae, Byung Joo Kim
Background: Gastrointestinal (GI) symptoms are common in the general population. This investigation studied the effects of Carthami flos (CF), a natural product, on GI motility. Methods: We checked the intestinal transit rates (ITRs) or gastric emptying in normal and in GI-motility-dysfunction (GMD) mice in vivo . The GMD mice were made by acetic acid or streptozotocin. Results: Both ITRs and gastric emptying were increased by CF (0.0025-0...
December 2017: Integrative medicine research
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