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Journal of Gynecology Obstetrics and Human Reproduction

Vasilios Tanos, Sayed ElAkhras, Baris Kaya
PURPOSE: To evaluate the hysteroscopic management on cervical pregnancy. MATERIALS AND METHODS: A case series report and literature review on patients with early first trimester cervical pregnancy (CP) treated by hysteroscopy. The symptoms upon admission, β-hCG levels, hysteroscopy technique, blood loss and operation outcomes were presented. RESULTS: Four patients with early CP between 5-7 weeks were successfully managed with operative hysteroscopy...
May 3, 2018: Journal of Gynecology Obstetrics and Human Reproduction
Erdogan Nohuz
BACKGROUND: The IOTA (International Ovarian Tumour Analysis) group has developed the ADNEX (Assessment of Different NEoplasias in the adneXa) model to predict the risk that an ovarian mass is benign, borderline or malignant. This study aimed to test reliability of these risks prediction models to improve the performance of pelvic ultrasound and discriminate between benign and malignant cysts. MATERIAL AND METHODS: Postmenopausal women with an adnexal mass (including ovarian, para-ovarian and tubal) and who underwent a standardized ultrasound examination before surgery were included...
April 27, 2018: Journal of Gynecology Obstetrics and Human Reproduction
Mélanie Korsakissok, Marion Groussolles, Odile Dicky, Corinne Alberge, Charlotte Casper, Corinne Azogui-Assouline
OBJECTIVE: To describe the morbidity and mortality and long-term neurodevelopmental outcomes in children born from a Twin-to-Twin Transfusion Syndrome (TTTS) pregnancy treated using laser fetoscopy in Toulouse. POPULATION AND METHOD: All pregnancies with TTTS treated by laser fetoscopy in our centre were included. Antenatal and postnatal morbidity and neonatal morbidity were identified in the medical records retrospectively. The neurodevelopmental outcome was studied using Ages and Stages Questionnaires (ASQ) sent to the parents, an oral interview with the parents and with the child's doctor (last objective neurological examination, rehabilitation needs, learning disabilities)...
April 23, 2018: Journal of Gynecology Obstetrics and Human Reproduction
Namita Agrawal, S Fayyaz
OBJECTIVES: To compare the diagnostic performance for tubal patency by chromopertubation and hysterosalpingography in the female infertile patients METHODS: We prospectively evaluated 103 female patients (age range 19-35 years; mean age 27.60 years) diagnosed as infertile, underwent hysterosalpingography (HSG) for tubal patency and uterine pathology during initial diagnostic work-up. All the enlisted patients fulfilled the criteria of infertility and these also underwent hysterolaparoscopic chromopertubation (CPT)...
April 21, 2018: Journal of Gynecology Obstetrics and Human Reproduction
Jaana Seikkula, Katja Ahinko, Päivi Polo-Kantola, Leena Anttila, Saija Hurme, Helena Tinkanen, Varpu Jokimaa
OBJECTIVE: To assess the effect of an additional single mid-luteal dose of gonadotropin-releasing hormone agonist (GnRHa) on pregnancy and perinatal outcomes in hormonally substituted frozen embryo transfer (FET) cycles. STUDY DESIGN: A prospective interventional pilot study. Women scheduled for FET were randomly selected to receive standard hormonal replacement therapy (HRT) for endometrial preparation or HRT with a single additional subcutaneous dose of 0.1mg triptorelin at the time of implantation...
April 20, 2018: Journal of Gynecology Obstetrics and Human Reproduction
Fanny Béchard, Julia Geronimi, Pierre Vieille, Vincent Letouzey, Renaud de Tayrac
INTRODUCTION: The aim of this study was to evaluate episiotomy technique, in particular suture angles, and any correlation between suture angle and severe perineal tears. MATERIAL AND METHODS: An observational questionnaire-based study was conducted between 01 August 2015 and 30 April 2016 among accoucheurs performing episiotomies in a French maternity unit with facilities for high-risk pregnancies. For each patient included, accoucheurs were asked to measure the episiotomy suture angle, and to record the angle at which they thought they had cut, the length of the episiotomy, its distance from the anus, and whether the woman sustained a sphincter injury...
April 19, 2018: Journal of Gynecology Obstetrics and Human Reproduction
Vincent Durous, Laurent Milot, Jean-Noël Buy, Bruno Deval, Pascal Rousset
We report the case of a 26-year-old woman with a right auto-amputated adnexa and a free- floating mass in the pouch of Douglas using multimodal imaging studies including ultrasonography, computed tomography, and magnetic resonance imaging. The absence of an ovary and the evidence of an amorphous and potentially calcified mass, with no connection to the genital tract - in particular when it is found to be mobile - are the key imaging findings. Prospective diagnosis of adnexal auto-amputation could assist surgeons in patient management with a curative laparoscopy in symptomatic women, or potentially expectant management in young women who are asymptomatic or have unrelated symptoms...
April 19, 2018: Journal of Gynecology Obstetrics and Human Reproduction
A Grouin, S Rouquette, M Saïdani, S Henno, V Lavoué, J Levêque
The authors report a case of a rare vulvar condition in a young cyclist, known as bicyclist's vulva. The diagnosis was based on the clinical context (intensive cycling training with repeated saddle sores, responsible for painless unilateral swelling of the labium majus to a significant size and functional discomfort). Imaging examinations were used to characterise the lesion and its relationship with the pelvic organs. The lesion was composed of connective tissue, poorly demarcated and heavily collagenised without necrotic or haemorrhagic areas...
April 16, 2018: Journal of Gynecology Obstetrics and Human Reproduction
C Garabedian, E Aubry, D Sharma, G Bleu, Y Clermont-Hama, L Ghesquière, T Hubert, P Deruelle, L Storme, J De Jonckheere, V Houfflin-Debarge
INTRODUCTION: Knowledge of fetal physiology during labor has been largely generated from animal models. Our team recently developed a new index to assess parasympathetic activity using different experimental protocols to obtain acidosis. The objective of the present study was to discuss the different protocols and to review other models proposed in the literature. MATERIAL AND METHODS: Pregnant ewes underwent a surgical procedure at the 123±2 days gestational age (term=145 days)...
April 11, 2018: Journal of Gynecology Obstetrics and Human Reproduction
Lea Delbos, Pierre Emmanuel Bouet, Laurent Catala, Celine Lefebvre, Carlos Teyssedou, Philippe Descamps, Guillaume Legendre
OBJECTIVE: The principal objective of our study was to assess women's quality of life (QoL) after surgery for Deep Endometriosis (DE), according to the surgical technique used. MATERIAL AND METHODS: Qualitative single-center survey in the department of obstetrics and gynecology, Angers University Hospital Center, France. All women who underwent surgery for DE from January 2011 to December 2015 were contacted by phone. The Endometriosis Health Profile-5 score was used to assess QoL before and after the surgery...
April 11, 2018: Journal of Gynecology Obstetrics and Human Reproduction
E Nohuz, N Bourdel
Ovaries and fallopian tubes are frequently affected by cystic pathology. Laparoscopic surgery to perform cystectomy, oophorectomy and salpingo-oophorectomy is the gold standard for the treatment of the presumed benign adnexal cysts [1,2]. Although their malignant transformation is a rare eventuality, the rules of oncological surgery stipulate that efforts must be used to prevent any risk of tumor dissemination if the definitive anatomopathological examination prove to be malignant [2-5]. Since open cystectomy exposes at the risk of cell dissemination, we most often perform closed cystectomy where possible...
April 11, 2018: Journal of Gynecology Obstetrics and Human Reproduction
A Rosefort, C Huchon, S Estrade, A Paternostre, J-P Bernard, A Fauconnier
OBJECTIVES: To assess and compare the diagnostic accuracy of transvaginal ultrasonography (TVUS) by trained or untrained ultrasound operators in deep infiltrating endometriosis (DIE) imaging, for diagnosing DIE and bowel involvement. METHODS: This was an observational study of patients with clinically suspected DIE operated in a reference center. TVUS was performed pre-operatively by a trained or/and untrained ultrasound operator to search for DIE and rectal involvement...
April 11, 2018: Journal of Gynecology Obstetrics and Human Reproduction
Eva Sangnier, Marine Lallement, Perrine Moussy-Berteaux, Mayi Gnofam, Laurence Bednarczyck, Emile Mereb, Olivier Graesslin
OBJECTIVE: To compare postoperative pain after single port laparoscopy (SPL) approach with conventional laparoscopy (CL) in case of adnexectomy. MATERIAL AND METHODS: This is a retrospective monocentric study involving patients who underwent adnexal surgery by SPL or CL for a suspected benign disease or as a preventive measure. The main outcome measure was the level of postoperative pain. RESULTS: A total of 87 patients were enrolled. Within 2hours, the numerical scale (NS) was 1...
April 11, 2018: Journal of Gynecology Obstetrics and Human Reproduction
Romuald Ferre, Pierre-Alain Goumot, Benoît Mesurolle
OBJECTIVES: To assess the benefit of stereoscopic digital mammography in daily practice. METHODS: Stereoscopic digital (SD) mammography allows a fused 3D view of mammogram. A 4-degree cranio-caudal (CC) angle view matched with a regular CC view allows generating a stereoscopic view Three breast radiologists reviewed retrospectively 1,110 stereoscopic digital mammograms (1075 women) performed between November 2011 and February 2013 with the following sequence: each evaluated firstly conventional mammogram alone, and then integrated SD mammograms...
April 2, 2018: Journal of Gynecology Obstetrics and Human Reproduction
Xin Zheng, Shulin Chen, Linfang Li, Xiaohua Liu, Xiaomin Liu, Shuqin Dai, Peng Zhang, Huaiwu Lu, Zhongqiu Lin, Yuefei Yu, Guorong Li
OBJECTIVE: Serum human epididymis protein 4 (HE4) and transthyretin (TTR) are new markers for ovarian cancer. We compared HE4 and TTR with the gold marker CA-125 for the diagnosis of ovarian cancer patients. METHODS: 130 serum samples from benign ovarian tumor and 400 serum samples from healthy women were used to set up the cut-off. 126 serum samples from ovarian cancer patients before operation were collected to test the diagnostic value of these ELISA assays. The sensitivity, positive predictive value (PPV) and ROC curves were used to evaluate the diagnostic value...
March 30, 2018: Journal of Gynecology Obstetrics and Human Reproduction
Maximos Frountzas, Vasilios Pergialiotis, Anastasia Prodromidou, Konstantinos Kontzoglou, Despina N Perrea, Nikolaos Nikiteas
BACKGROUND: To date, the feasibility of pre-graduate training in 2D vision has not been studied thoroughly. The purpose of this pilot study is to present the preliminary results of a pre-graduate laparoscopic training program. MATERIALS AND METHODS: We invited pre-graduate medical students to participate in an experimental training program which strengthened their essential skills in 2D-vision. An easy-to-use, cost-effective, hand-made laparoscopic training box was constructed and used...
March 28, 2018: Journal of Gynecology Obstetrics and Human Reproduction
A Favre-Inhofer, A Rafii, M Carbonnel, A Revaux, J M Ayoubi
Uterine transplantation is the solution to treat absolute uterine fertility. In this review, we present the historical, medical, technical, psychological and ethical perspectives in human uterine transplantation research. We reviewed the PubMed database following PRISMA guidelines and added data presented by several research teams during the first international congress on uterine transplantation.
March 21, 2018: Journal of Gynecology Obstetrics and Human Reproduction
J Vignolle, C Lefebvre, J P Lucot, C Rubod
This article reports a case of cervico-isthmic disjunction unnoticed during childhood, diagnosed in a context of primary infertility and endometriosis, and surgically treated. It is an uncommon condition. The diagnosis is most often made as part of an assessment of primary amenorrhea in a young woman with a history of severe pelvic trauma. It is suspected after imaging assessment and confirmed intraoperatively. The treatment consists in an anastomosis between the cervix and the uterine body, after individualizing these two structures, around a drain guiding healing...
March 21, 2018: Journal of Gynecology Obstetrics and Human Reproduction
M de Ciantis, C Faure, P-E Heudel, O Tredan, C Rousset-Jablonski
In premenopausal women treated for breast cancer, endocrine therapy combining an aromatase inhibitor (AI) and a gonadotropin-releasing hormone (GnRH) agonist (GA) for ovarian suppression may be indicated in high-risk or in metastatic cancer. AIs are effective in premenopausal women only when ovarian estrogen production is suppressed, a state achievable through the use of GAs. However, a complete suppression sometimes proves elusive. We report here three cases of ovarian suppression failure in premenopausal breast cancer patients who received adjuvant AI+GA...
March 3, 2018: Journal of Gynecology Obstetrics and Human Reproduction
P Panel, M-E Neveu, C Villain, F Debras, H Fernandez, E Debras
OBJECTIVE: The objective was to compare results of two groups of population (novices and experts) on a virtual reality simulator of hysteroscopy resection for different metrics and for a multimetric score to assess its construct validity. MATERIALS AND METHODS: Nineteen gynecologist who had at least 5 years of experience with hysteroscopy and self-evaluated their expertise at 4/5 or 5/5 were included as expert population. Twenty first-year gynecology residents in Paris were included as novice population...
March 3, 2018: Journal of Gynecology Obstetrics and Human Reproduction
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