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Acta Medica Lituanica

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https://www.readbyqxmd.com/read/29928157/risk-factors-of-developing-the-hungry-bone-syndrome-after-parathyroidectomy-for-primary-hyperparathyroidism
#1
Matas Jakubauskas, Virgilijus Beiša, Kęstutis Strupas
Background: Around 13% of patients undergoing parathyroidectomy for primary hyperparathyroidism (PHPT) postoperatively develop a condition known as the hungry bone syndrome (HBS). Although the condition is quite prevalent, the research in this field is very limited. The aim of our study was to determine possible risk factors of developing HBS after parathyroidectomy for PHPT. Materials and methods: In this study we enrolled patients who underwent parathyroidectomy for PHPT from January 2005 to December 2016 and performed a retrospective analysis...
2018: Acta Medica Lituanica
https://www.readbyqxmd.com/read/29928156/recommendations-and-a-guideline-for-referral-of-infantile-haemangioma-to-tertiary-centres
#2
Arūnas Strumila, Rūta Vilija Dagilytė, Virgilijus Beiša
Background: Infantile haemangioma is the most common childhood vascular tumour, which causes great anxiety to parents and treating first-line physicians due to its proliferative nature. It accounts for a large percentage of a tertiary centre consultations, thus delaying consultation time for patients in need of immediate care. Materials and methods: Review of literature and experience of treatment and observation of infantile haemangiomas in a tertiary centre of paediatric surgery...
2018: Acta Medica Lituanica
https://www.readbyqxmd.com/read/29928155/malignant-mixed-epithelial-and-stromal-tumour-of-the-kidney-a-case-report-and-a-literature-review
#3
Arnas Bakavičius, Marija Barisienė, Marius Snicorius, Dileta Valančienė, Darius Dasevičius, Algirdas Žalimas, Robertas Kvaščevičius, Henrikas Ramonas, Vitalijus Sokolovas, Feliksas Jankevičius
Introduction: Mixed epithelial and stromal tumour of the kidney (MEST) is a rare and distinctive neoplasm accounting for 0.2% of all renal cancers. Most of these tumours behave in a benign fashion but 13 cases with malignant transformation have already been reported. We present the first case of an extremely aggressive MEST with rapid recurrence after radical treatment, demonstrating objective response to chemotherapy. Case presentation: A 31-year-old female presented to the hospital complaining of gross hematuria...
2018: Acta Medica Lituanica
https://www.readbyqxmd.com/read/29928154/primary-gastric-burkitt-lymphoma-induced-anaemia-a-case-report-and-a-literature-review
#4
Monika Kapitančukė, Agnija Vaščiūnaitė, Rasa Augustinienė, Jūratė Sakalinskienė, Gražina Kleinotienė
Background: Primary tumours of the gastrointestinal tract are very uncommon in children. They can present with anaemia caused by gastrointestinal acute or chronic bleeding. One of the most common gastrointestinal tumours is Burkitt lymphoma. This lymphoma is a highly aggressive, rapidly growing B-cell neoplasm, making survival without treatment possible only for a few weeks. For this reason it requires immediate hospitalization and treatment. Case report: We report a case of a gastric Burkitt lymphoma in an adolescent girl who presented with anaemia due to gastrointestinal bleeding...
2018: Acta Medica Lituanica
https://www.readbyqxmd.com/read/29928153/evaluation-of-pre-deliric-prediction-of-delirium-in-icu-patients-delirium-prediction-model-for-the-patients-in-the-intensive-care-unit
#5
Gabrielė Linkaitė, Mantas Riauka, Ignė Bunevičiūtė, Saulius Vosylius
Introduction: Delirium not only compromises patient care, but is also associated with poorer outcomes: increased duration of mechanical ventilation, higher mortality, and greater long-term cognitive dysfunction. The PRE-DELIRIC model is a tool used to calculate the risk of the development of delirium. The classification of the patients into groups by risk allows efficient initiation of preventive measures. The goal of this study was to validate the PRE-DELIRIC model using the CAM-ICU (The Confusion Assessment Method for the Intensive Care Unit) method for the diagnosis of delirium...
2018: Acta Medica Lituanica
https://www.readbyqxmd.com/read/29928152/novel-human-genome-variants-associated-with-alcohol-use-disorders-identified-in-a-lithuanian-cohort
#6
Karolis Baronas, Tautvydas Rančelis, Aidas Pranculis, Ingrida Domarkienė, Laima Ambrozaitytė, Vaidutis Kučinskas
Background: Alcohol use disorder (AUD) is a chronic relapsing brain disease characterized by compulsive alcohol use, loss of control over alcohol intake, and a negative emotional state when not using (1). Abusive alcohol consumption directly affects a person's physical and psychological health and social life. The World Health Organization has shown that Lithuania is a leading country in pure alcohol consumption in the world (2). The aim of this study is to find novel genome variants that are associated with the AUD in the Lithuanian cohort...
2018: Acta Medica Lituanica
https://www.readbyqxmd.com/read/29928151/a-rare-case-of-rem-sleep-related-bradyarrhythmia-syndrome-with-concomitant-severe-hypertension-a-case-report-and-a-review-of-literature
#7
Gabrielius Jakutis, Vytautas Juknevičius, Juratė Barysienė, Dalia Matačiūnienė, Birutė Petrauskienė, Žaneta Petrulionienė, Aleksandras Laucevičius
Introduction: Rapid eye movement (REM) sleep-related bradyarrhythmia syndrome is characterized by pathological asystoles during the REM sleep phase. It is a rare rhythm disorder, being reported only few times in the literature. Due to non-specific symptoms, REM sleep-related bradyarrhythmia might be often underdiagnosed. Other cardiac diseases associated with pathological sinus arrests must be excluded to establish the correct diagnosis of and appropriate therapy for REM sleep-related bradyarrhythmia...
2018: Acta Medica Lituanica
https://www.readbyqxmd.com/read/29487484/relationships-between-pulmonary-function-test-parameters-and-quantitative-computed-tomography-measurements-of-emphysema-in-subjects-with-chronic-obstructive-pulmonary-disease
#8
Virginija Šileikienė, Marius Urbonas, Mindaugas Matačiūnas, Jolita Norkūnienė
Objective: CT is able to precisely define the pathological process in COPD. There are a number of previous articles discussing the distribution of emphysema and its connection with pulmonary function tests. However, the results obtained by the researchers are not identical. Purpose: To assess relationships between emphysema and pulmonary function test parameters in COPD patients. Materials and methods: Fifty-nine patients diagnosed to have COPD underwent chest CT examinations and pulmonary function tests...
2017: Acta Medica Lituanica
https://www.readbyqxmd.com/read/29487483/survival-of-children-treated-for-ewing-sarcoma-in-lithuania-a-single-centre-experience
#9
Gabrielius Jakutis, Lina Ragelienė, Jelena Rascon
Introduction: Ewing sarcoma (ES) is a rare and aggressive malignant neoplasm that mostly affects children and adolescents. Recent studies reported a gap of 20% in childhood cancer survival rates between the Northern/Western and the Eastern European countries. We aimed to analyse the survival of patients treated for ES at our institution, to evaluate its correspondence to current survival rates in the expert centres, and to assess changes in treatment outcomes over time. Materials and methods: A retrospective single-centre study was performed...
2017: Acta Medica Lituanica
https://www.readbyqxmd.com/read/29487482/respiratory-syncytial-virus-infection-in-a-selected-sample-of-infants-hospitalized-for-lower-respiratory-tract-infection-in-lithuania-and-estonia
#10
Nijolė Drazdienė, Mari Laan, Jolanta Zaikauskienė, Vytautas Usonis
Background: The study presents data on a sample of children under one year of age hospitalized with lower respiratory tract infections (LRTIs) in Lithuania and Estonia. Subjects and methods: This large, retrospective, cross-sectional, observational epidemiologic survey was conducted in 12 countries in Central and Eastern Europe. Eligible subjects were under one year of age, hospitalized for LRTIs, for whom RDT (Rapid Diagnostic Test) was performed. Physicians completed questionnaires at discharge or on the first check-up visit after hospitalization...
2017: Acta Medica Lituanica
https://www.readbyqxmd.com/read/29487481/the-role-of-mmp-1-and-fgfr4-r388-gene-polymorphisms-in-pituitary-adenoma
#11
Eglė Zlatkutė, Rasa Liutkevičienė, Alvita Vilkevičiūtė, Brigita Glebauskienė, Loresa Kriaučiūnienė, Silvija Jakštienė, Dalia Žaliūnienė
Background: The pathogenesis of pituitary adenoma (PA) is complex and poorly understood. It is thought that PA has a multifactorial aetiology; genetic factors also have an impact on PA development. Since MMP1 and FGFR4 genes play an important role in tumour growth, differentiation and progression, we decided to determine if the frequency of the genotypes of MMP-1 and FGFR4-R388 polymorphisms influence the development of PA. Materials and methods: The study enrolled n = 100 patients with PA and n = 200 healthy controls (reference group)...
2017: Acta Medica Lituanica
https://www.readbyqxmd.com/read/29217973/hybrid-transanal-and-total-mesorectal-excision-after-transanal-endoscopic-microsurgery-for-unfavourable-early-rectal-cancer-a-report-of-two-cases
#12
Narimantas E Samalavičius, Audrius Dulskas, Kęstutis Petrulis, Alfredas Kilius, Renatas Tikuišis, Raimundas Lunevičius
Completion total mesorectal excision (TME) is a rare but complex procedure after transanal endoscopic microsurgery for early rectal cancer with unfavourable final histology. Two cases are reported when completion TME was performed after upfront transanal partial mesorectal dissection. Intact non-perforated TME specimens with negative and adequate distal and circumferential margins were created. The quality of both total mesorectal excisions was complete and distal margins were sufficient. We believe that our technique might be a way of approaching completion TME after TEM, especially in cases of low rectal cancer...
2017: Acta Medica Lituanica
https://www.readbyqxmd.com/read/29217972/clinical-aspects-and-antenatal-diagnosis-of-invasive-placenta-a-review-of-ten-years-experience-of-a-multi-profile-hospital-in-lithuania
#13
Jelena Volochovič, Diana Ramašauskaitė, Ramunė Šimkevičiūtė
Background: Invasive placenta is a rare obstetrical pathology that is life-threatening to mother and child. It is important to diagnose this pathology as early as possible and to plan further optimal care of patients in order to minimize life-threatening complications. The aim of this study was to analyze the frequency of cases of invasive placenta, the peculiarities of their clinical manifestation in women who gave birth from 2006 to 2015, to evaluate diagnostic and treatment options of this pathology, and to review their changes when the level of services provided by the institution changes...
2017: Acta Medica Lituanica
https://www.readbyqxmd.com/read/29217971/evaluation-of-the-relationship-between-the-occlusion-parameters-and-symptoms-of-the-temporomandibular-joint-disorder
#14
Agnė Dzingutė, Gaivilė Pileičikienė, Aušra Baltrušaitytė, Gediminas Skirbutis
Background: The aetiology of temporomandibular joint disorders (TMD) is multifactorial, whereas occlusal disharmony is one of the predisposing factors. Researchers still discuss the relation between occlusion and TMD. Objective: The study aims to investigate the relation between static occlusal parameters and TMD clinical symptoms using T-Scan II analysis system. Material and methods: The sample consisted of 44 persons divided into the treatment group of 20 TMD patients and the control group of 24 subjects without TMD...
2017: Acta Medica Lituanica
https://www.readbyqxmd.com/read/29217970/recurrent-pericarditis-a-case-report-and-literature-review
#15
Justina Katinaitė, Birutė Petrauskienė
Background: Recurrence affects about 30% (20% to 50%) of patients within 18 months after the initial episode of acute pericarditis resulting in subsequent rehospitalizations. Bearing in mind high treatment costs of patients admitted to hospital with acute and recurrent pericarditis, there is a need to optimize the treatment of both of these conditions. Materials and methods: We present a case of recurrent pericarditis. The first episode of pericarditis was diagnosed in 2006...
2017: Acta Medica Lituanica
https://www.readbyqxmd.com/read/29217969/severity-of-hyperoxia-as-a-risk-factor-in-patients-undergoing-on-pump-cardiac-surgery
#16
Gabrielius Jakutis, Ieva Norkienė, Donata Ringaitienė, Tomas Jovaiša
Background: Hyperoxia has long been perceived as a desirable or at least an inevitable part of cardiopulmonary bypass. Recent evidence suggest that it might have multiple detrimental effects on patient homeostasis. The aim of the study was to identify the determinants of supra-physiological values of partial oxygen pressure during on-pump cardiac surgery and to assess the impact of hyperoxia on clinical outcomes. Materials and methods: Retrospective data analysis of the institutional research database was performed to evaluate the effects of hyperoxia in patients undergoing elective cardiac surgery with cardiopulmonary bypass, 246 patients were included in the final analysis...
2017: Acta Medica Lituanica
https://www.readbyqxmd.com/read/29217968/investigation-of-markers-of-allergic-sensitization-and-viral-infections-in-children-with-allergy-and-asthma
#17
Rūta Dubakienė, Vilija Rubinaitė, Malvina Petronytė, Indrė Dalgėdienė, Odilija Rudzevičienė, Dalia Dubakaitė, Palmira Rudalevičienė, Aurelija Žvirblienė
Background: Allergic diseases are the most prevalent chronic diseases in the developed countries. It is believed that early allergic sensitization and respiratory viral infections play an important role in the development of allergic diseases and asthma. Methods: The current study investigated the correlation between asthma, allergy, and various markers - allergen-specific IgE, IgG4 and IgA, ECP, IgM, and IgG antibodies against respiratory viruses hRSV and hPIV1-4 - in blood serum samples from 80 children (mean age 5...
2017: Acta Medica Lituanica
https://www.readbyqxmd.com/read/28845132/cell-free-dna-in-non-small-cell-lung-cancer
#18
Vaida Gedvilaitė, Diana Schveigert, Saulius Cicėnas
Lung cancer is the leading cause of cancer-associated deaths worldwide. Surgery is the standard treatment for early-stage non-small cell lung cancer (NSCLC). Advances in the knowledge of the biology of non-small cell lung cancer have revealed molecular information used for systemic cancer therapy targeting metastatic disease, with an important impact on patients' overall survival (OS) and quality of life. However, a biopsy of overt metastases is an invasive procedure limited to certain locations and not easily acceptable in the clinic...
2017: Acta Medica Lituanica
https://www.readbyqxmd.com/read/28845131/results-of-neuroblastoma-treatment-in-lithuania-a-single-centre-experience
#19
Austėja Juškaitė, Indrė Tamulienė, Jelena Rascon
BACKGROUND: Neuroblastoma (NB) is the most common extracranial solid tumour in children. This is a very rare disease with heterogeneous biology varying from complete spontaneous regression to a highly aggressive tumour responsible for 15% of malignancy-related death in early childhood. Analyses of survival rates in Europe have shown a considerable difference between Northern/Western and Eastern European countries. Treatment results of NB in Lithuania have never been analyzed. AIM: To assess the survival rate of children with NB according to initial spread of the disease, age at diagnosis, the MYCN amplification, risk group, and treatment period...
2017: Acta Medica Lituanica
https://www.readbyqxmd.com/read/28845130/anaesthetic-challenges-in-cancer-patients-current-therapies-and-pain-management
#20
Jūratė Gudaitytė, Dominykas Dvylys, Indrė Šimeliūnaitė
THE OBJECTIVE: The aim is to present the major effects of cancer treatment (chemotherapy, radiotherapy, surgery) that the anaesthesiologist should consider preoperatively, and to review techniques of the analgesic management of the disease. MATERIALS AND METHODS: To summarize the major challenges that cancer patients present for the anaesthesiologists, a literature review was conducted. Articles presenting evidence or reviewing the possible effects of anaesthetics on cancer cells were also included...
2017: Acta Medica Lituanica
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