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Acta Medica Lituanica

Sigita Stropuvienė, Asta Baranauskaitė, Loreta Bukauskienė, Jolanta Zaikauskienė
Background: To provide data on the use of anti-cyclic citrullinated peptide antibody (anti-CCP) and other routinely used clinical parameters and to assess the impact of anti-CCP status on therapeutic decisions, an observational study was conducted in patients with rheumatoid arthritis (RA). Methods: Sixty-seven adult patients with a recent diagnosis of RA were recruited from four rheumatology centres in Lithuania and were prospectively observed for 12 months. Data collection was based on the review of medical records and routine examination of patients...
2018: Acta Medica Lituanica
Darja Rojaka, Sigita Lesinskienė
Background: The tradition of celebrating the day of birth of an individual is thought to have existed since the ancient times. Depending on the culture, religious beliefs, and the geographic location, occasions for ritual performance differ greatly. The aim of this pilot study was to investigate how students in Lithuania evaluate the importance of their birthday. Materials and methods: An "Invitation to Remember Your Birthday" questionnaire was created by the authors to collect the responses for evaluation...
2018: Acta Medica Lituanica
Domantė Kučikienė, Rūta Praninskienė
In this article we conclude the main scientific studies into the changes in the bioelectrical brainwave activity that occur while listening to music. A brainwave spectral analysis, derived from findings of electroencephalograms, is a powerful tool to obtain deep and objective insights into the effects of music on the brain. This capacity is being investigated in various contexts. Starting with a healthy population, studies also seek to determine the impact of music in such conditions as disorders of consciousness, psychiatric diseases, and chronic conditions, as well as to further explore the role of music for rehabilitation purposes...
2018: Acta Medica Lituanica
Julita Račaitė, Alina Šumkovskaja, Audronė Arlauskienė, Ingrida Pilypienė, Elena Landsbergytė-Bukauskienė
Background: A congenital cystic adenomatoid malformation (CCAM) is a foetal pulmonary development abnormality caused by airway dysgenesis that is characterized by cystic or adenomatous lesions in the terminal bronchioles. The size of the mass, the degree of the mediastinal shift, and the presence of hydrops and polyhydramnios can all affect the severity of a case. Treatment can be initiated at early stages by applying prenatal and postnatal methods. Because CCAM is a rare pathology that is often only accidentally diagnosed during routine ultrasounds, we would like to share our case report to enrich the literature on this pathology and to present a case successfully treated at our hospital...
2018: Acta Medica Lituanica
Liene Smane, Mara Pilmane
Cleft lip and palate (CLP) is the most common defect affecting the face. The treatment consists of surgical reconstruction of the anatomical structures of the cleft. Part of the surgical treatment is reconstruction of the alveolar bone by means of autogenic bone grafting (osteoplasty). This study aimed to evaluate the levels of expression of extracellular matrix remodeling factors in the facial tissue of children with a complete unilateral (CU) and a complete bilateral (CB) CLP to assess whether the wound healing process is adequate...
2018: Acta Medica Lituanica
Nijolė Drazdienė, Rasa Tamelienė, Daiga Kviluna, Pille Saik, Ervin Saik, Jolanta Zaikauskienė
Background: By two years of age, almost all children experience at least one episode of respiratory syncytial virus (RSV) infection, the most common viral cause of hospitalisation due to lower respiratory tract infection (LRTI). We present data on LRTI hospitalisations (with a special focus on RSV), the course of illness, and LRTI hospitalisation risk factors in Lithuania, Latvia, and Estonia. Materials and methods: The analysed data were part of a large multinational study conducted in 23 countries (PONI)...
2018: Acta Medica Lituanica
Laura Steponavičienė, Daiva Gudavičienė, Rūta Briedienė, Donatas Petroška, Aušra Garnelytė
Background: Encapsulated papillary carcinoma (EPC) is a rare entity of breast cancer accounting for approximately 1-2% of all breast tumours. There are no evidence-based guidelines for the treatment of EPC. Materials and methods: From the database of the National Centre of Pathology (NCP), we obtained pathology reports of 19 patients with histologically confirmed EPC, who were treated at the National Cancer Institute (NCI) in Vilnius, Lithuania, between July 2009 and July 2015...
2018: Acta Medica Lituanica
Dalia Laužikienė, Saulius Vosylius, Ieva Šiaudinytė, Emilis Laužikas, Diana Ramašauskaitė, Daiva Bartkevičienė
Background: Uterine rupture at the site of a previous caesarean scar with abnormal placental penetration through the uterus wall with bladder invasion is a rare and serious pregnancy complication. Our aim was to report a case of uterine rupture with placenta percreta complicated by thrombotic microangiopathy. Materials and methods: We did a literature review and analysed medical documentation retrospectively. Results: A patient was admitted with complaints of lower abdominal pain at 21 weeks of gestation...
2018: Acta Medica Lituanica
Raimondas Juškys, Gytis Šustickas
Background: There is a great deal of tools for treatment of occipital neuralgia but currently we are lacking a complete consensus among practitioners regarding the optimal approach to this debilitating condition. Occipital nerve block (ONB) is known as one of the management options but there is lack of scientific literature exploring its effectiveness. Materials and methods: The prospective study was undertaken between March 2014 and February 2018 at the State Vilnius University Hospital...
2018: Acta Medica Lituanica
Matas Jakubauskas, Virgilijus Beiša, Kęstutis Strupas
Background: Around 13% of patients undergoing parathyroidectomy for primary hyperparathyroidism (PHPT) postoperatively develop a condition known as the hungry bone syndrome (HBS). Although the condition is quite prevalent, the research in this field is very limited. The aim of our study was to determine possible risk factors of developing HBS after parathyroidectomy for PHPT. Materials and methods: In this study we enrolled patients who underwent parathyroidectomy for PHPT from January 2005 to December 2016 and performed a retrospective analysis...
2018: Acta Medica Lituanica
Arūnas Strumila, Rūta Vilija Dagilytė, Virgilijus Beiša
Background: Infantile haemangioma is the most common childhood vascular tumour, which causes great anxiety to parents and treating first-line physicians due to its proliferative nature. It accounts for a large percentage of a tertiary centre consultations, thus delaying consultation time for patients in need of immediate care. Materials and methods: Review of literature and experience of treatment and observation of infantile haemangiomas in a tertiary centre of paediatric surgery...
2018: Acta Medica Lituanica
Arnas Bakavičius, Marija Barisienė, Marius Snicorius, Dileta Valančienė, Darius Dasevičius, Algirdas Žalimas, Robertas Kvaščevičius, Henrikas Ramonas, Vitalijus Sokolovas, Feliksas Jankevičius
Introduction: Mixed epithelial and stromal tumour of the kidney (MEST) is a rare and distinctive neoplasm accounting for 0.2% of all renal cancers. Most of these tumours behave in a benign fashion but 13 cases with malignant transformation have already been reported. We present the first case of an extremely aggressive MEST with rapid recurrence after radical treatment, demonstrating objective response to chemotherapy. Case presentation: A 31-year-old female presented to the hospital complaining of gross hematuria...
2018: Acta Medica Lituanica
Monika Kapitančukė, Agnija Vaščiūnaitė, Rasa Augustinienė, Jūratė Sakalinskienė, Gražina Kleinotienė
Background: Primary tumours of the gastrointestinal tract are very uncommon in children. They can present with anaemia caused by gastrointestinal acute or chronic bleeding. One of the most common gastrointestinal tumours is Burkitt lymphoma. This lymphoma is a highly aggressive, rapidly growing B-cell neoplasm, making survival without treatment possible only for a few weeks. For this reason it requires immediate hospitalization and treatment. Case report: We report a case of a gastric Burkitt lymphoma in an adolescent girl who presented with anaemia due to gastrointestinal bleeding...
2018: Acta Medica Lituanica
Gabrielė Linkaitė, Mantas Riauka, Ignė Bunevičiūtė, Saulius Vosylius
Introduction: Delirium not only compromises patient care, but is also associated with poorer outcomes: increased duration of mechanical ventilation, higher mortality, and greater long-term cognitive dysfunction. The PRE-DELIRIC model is a tool used to calculate the risk of the development of delirium. The classification of the patients into groups by risk allows efficient initiation of preventive measures. The goal of this study was to validate the PRE-DELIRIC model using the CAM-ICU (The Confusion Assessment Method for the Intensive Care Unit) method for the diagnosis of delirium...
2018: Acta Medica Lituanica
Karolis Baronas, Tautvydas Rančelis, Aidas Pranculis, Ingrida Domarkienė, Laima Ambrozaitytė, Vaidutis Kučinskas
Background: Alcohol use disorder (AUD) is a chronic relapsing brain disease characterized by compulsive alcohol use, loss of control over alcohol intake, and a negative emotional state when not using (1). Abusive alcohol consumption directly affects a person's physical and psychological health and social life. The World Health Organization has shown that Lithuania is a leading country in pure alcohol consumption in the world (2). The aim of this study is to find novel genome variants that are associated with the AUD in the Lithuanian cohort...
2018: Acta Medica Lituanica
Gabrielius Jakutis, Vytautas Juknevičius, Juratė Barysienė, Dalia Matačiūnienė, Birutė Petrauskienė, Žaneta Petrulionienė, Aleksandras Laucevičius
Introduction: Rapid eye movement (REM) sleep-related bradyarrhythmia syndrome is characterized by pathological asystoles during the REM sleep phase. It is a rare rhythm disorder, being reported only few times in the literature. Due to non-specific symptoms, REM sleep-related bradyarrhythmia might be often underdiagnosed. Other cardiac diseases associated with pathological sinus arrests must be excluded to establish the correct diagnosis of and appropriate therapy for REM sleep-related bradyarrhythmia...
2018: Acta Medica Lituanica
Virginija Šileikienė, Marius Urbonas, Mindaugas Matačiūnas, Jolita Norkūnienė
Objective: CT is able to precisely define the pathological process in COPD. There are a number of previous articles discussing the distribution of emphysema and its connection with pulmonary function tests. However, the results obtained by the researchers are not identical. Purpose: To assess relationships between emphysema and pulmonary function test parameters in COPD patients. Materials and methods: Fifty-nine patients diagnosed to have COPD underwent chest CT examinations and pulmonary function tests...
2017: Acta Medica Lituanica
Gabrielius Jakutis, Lina Ragelienė, Jelena Rascon
Introduction: Ewing sarcoma (ES) is a rare and aggressive malignant neoplasm that mostly affects children and adolescents. Recent studies reported a gap of 20% in childhood cancer survival rates between the Northern/Western and the Eastern European countries. We aimed to analyse the survival of patients treated for ES at our institution, to evaluate its correspondence to current survival rates in the expert centres, and to assess changes in treatment outcomes over time. Materials and methods: A retrospective single-centre study was performed...
2017: Acta Medica Lituanica
Nijolė Drazdienė, Mari Laan, Jolanta Zaikauskienė, Vytautas Usonis
Background: The study presents data on a sample of children under one year of age hospitalized with lower respiratory tract infections (LRTIs) in Lithuania and Estonia. Subjects and methods: This large, retrospective, cross-sectional, observational epidemiologic survey was conducted in 12 countries in Central and Eastern Europe. Eligible subjects were under one year of age, hospitalized for LRTIs, for whom RDT (Rapid Diagnostic Test) was performed. Physicians completed questionnaires at discharge or on the first check-up visit after hospitalization...
2017: Acta Medica Lituanica
Eglė Zlatkutė, Rasa Liutkevičienė, Alvita Vilkevičiūtė, Brigita Glebauskienė, Loresa Kriaučiūnienė, Silvija Jakštienė, Dalia Žaliūnienė
Background: The pathogenesis of pituitary adenoma (PA) is complex and poorly understood. It is thought that PA has a multifactorial aetiology; genetic factors also have an impact on PA development. Since MMP1 and FGFR4 genes play an important role in tumour growth, differentiation and progression, we decided to determine if the frequency of the genotypes of MMP-1 and FGFR4-R388 polymorphisms influence the development of PA. Materials and methods: The study enrolled n = 100 patients with PA and n = 200 healthy controls (reference group)...
2017: Acta Medica Lituanica
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