Manuel Joaquín Romero-López, Hilda Jiménez-Wences, Merlin Itsel Cruz-De La Rosa, Judit Alarcón-Millán, Miguel Ángel Mendoza-Catalán, Elizabeth Ortiz-Sánchez, José Manuel Tinajero-Rodríguez, Daniel Hernández-Sotelo, Gladys Wendy Valente-Niño, Dinorah Nashely Martínez-Carrillo, Gloria Fernández-Tilapa
BACKGROUND: In cervical cancer (CC), miR-218-5p, -124-3p, and -23b-3p act as tumor suppressors. These miRNAs have specific and common target genes that modulate apoptosis, proliferation, invasion, and migration; biological processes involved in cancer. METHODS: miR-218-5p, -124-3p, and -23b-3p mimics were transfected into C-33A and CaSki cells, and RT-qPCR was used to quantify the level of each miRNA and NACC1 . Proliferation was assessed by BrdU and apoptosis by Annexin V/PI...
September 2024: Non-Coding RNA Research