Yan-Yuan Xiao, Qing Zhang, Fei Huang, Lin Rao, Tian-Xiong Yao, Si-Yu Yang, Lei Xie, Xiao-Xiao Zou, Li-Ping Cai, Jia-Wen Yang, Bin Yang, Lu-Sheng Huang
The gastrointestinal tract is essential for food digestion, nutrient absorption, waste elimination, and microbial defense. Single-cell transcriptome profiling of the intestinal tract has greatly enriched our understanding of cellular diversity, functional heterogeneity, and their importance in intestinal tract development and disease. Although such profiling has been extensively conducted in humans and mice, the single-cell gene expression landscape of the pig cecum remains unexplored. Here, single-cell RNA sequencing was performed on 45 572 cells obtained from seven cecal samples in pigs at four different developmental stages (days (D) 30, 42, 150, and 730)...
January 18, 2024: Zoological Research