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International Journal of Retina and Vitreous

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https://www.readbyqxmd.com/read/30214825/change-in-subfoveal-choroidal-thickness-in-diabetes-and-in-various-grades-of-diabetic-retinopathy
#1
Vikas Ambiya, Ashok Kumar, V K Baranwal, Gaurav Kapoor, Amit Arora, Nidhi Kalra, Jyoti Sharma
Background: To evaluate subfoveal choroidal thickness (SFCT) change in diabetes and in various grades of diabetic retinopathy (DR) in comparison to age-matched healthy subjects. Methods: This prospective observational study included 100 eyes of diabetic patients without DR (group D), 100 eyes with DR (group R), and 100 eyes of healthy subjects (group N). The assessment included demographics, duration of diabetes, comprehensive ocular examination, fundus photography with/without fundus fluorescein angiography, spectral domain optical coherence tomography with enhanced depth imaging to assess SFCT...
2018: International Journal of Retina and Vitreous
https://www.readbyqxmd.com/read/30202602/retina-and-glaucoma-surgical-complications
#2
REVIEW
Niroj Kumar Sahoo, Pasyanthi Balijepalli, Sumit Randhir Singh, Mahima Jhingan, Sirisha Senthil, Jay Chhablani
Background: The close structural and microcirculatory co-relation between anterior and posterior segments of eye make them very vulnerable to complications when one of them is affected surgically. With the advent of anti-fibrotic agents in the management of glaucoma, the rates of vitreoretinal complications have become more frequent. Main body: Common retinal complications after glaucoma surgeries include choroidal detachment; ocular decompression retinopathy; haemorrhagic choroidal detachment; hypotony maculopathy; malignant glaucoma; vitreous haemorrhage; bleb endophthalmitis; retinal detachment...
2018: International Journal of Retina and Vitreous
https://www.readbyqxmd.com/read/30181904/clinical-course-of-acute-zonal-occult-outer-retinopathy-complicated-by-choroidal-neovascularization
#3
Ugo Introini, Giuseppe Casalino, Elona Dhrami-Gavazi, Sri Krishna Mukkamala, Sarah Mrejen, Hermann Schubert, Salomon Y Cohen, Claudio Azzolini, Francesco Bandello, Stanley Chang, Lawrence A Yannuzzi
Purpose: To report the clinical course and multimodal imaging features of acute zonal occult outer retinopathy (AZOOR) complicated by choroidal neovascularization (CNV) treated with anti-vascular endothelial growth factor (VEGF) treatment or photodynamic therapy (PDT). Methods: Observational case series. Retrospective analysis of patients presenting to different institutions with evidence of AZOOR and neovascular lesions. Diagnosis of AZOOR was made on the basis of clinical presentation and multimodal imaging...
2018: International Journal of Retina and Vitreous
https://www.readbyqxmd.com/read/30151240/direct-navigated-laser-photocoagulation-as-primary-treatment-for-retinal-arterial-macroaneurysms
#4
Dmitrii S Maltsev, Alexei N Kulikov, Bhushan Uplanchiwar, Luiz H Lima, Jay Chhablani
Objectives: To compare the efficacy and safety of conventional and navigated laser photocoagulation as the primary treatment option for retinal arteriolar macroaneurysm (RAM). Methods: Eleven (9 male and 2 females, mean age 65.1 ± 12.1 years) and 17 (13 male and 4 females, mean age 66.2 ± 8.9 years) patients were included in conventional laser photocoagulation (CLP) and navigated laser photocoagulation (NLP) groups, respectively. The primary outcome measures were LogMAR best-corrected visual acuity (BCVA) and central retinal thickness at the end of the follow-up...
2018: International Journal of Retina and Vitreous
https://www.readbyqxmd.com/read/30128167/multimodal-imaging-in-choroidal-osteoma
#5
Francisco Olguin-Manríquez, Ana Bety Enríquez, Nicolás Crim, Miroslava Meraz-Gutierrez, Vidal Soberón-Ventura, Ismael Ávila, Virgilio Morales-Canton, Juan Manuel Jimenez-Sierra
Purpose: To describe characteristics of choroidal osteomas (CO), using ocular ultrasound, fluorescein angiography, ultra-widefield retinal imaging, ultra-widefield autofluorescence, optical coherence tomography, enhanced-depth-imaging OCT, and OCT angiography (OCT-A). Methods: Retrospective, observational case series study. Clinical records from patients with diagnosis of CO who underwent complete imaging evaluation were analyzed. Results: Sixteen eyes from 11 patients were included...
2018: International Journal of Retina and Vitreous
https://www.readbyqxmd.com/read/30116590/sustained-and-targeted-episcleral-delivery-of-celecoxib-in-a-rabbit-model-of-retinal-and-choroidal-neovascularization
#6
Luiz H Lima, Michel E Farah, Glenwood Gum, Pamela Ko, Ricardo A de Carvalho
Background: To evaluate the efficacy of selective episcleral delivery of celecoxib formulated in a sustained-release episcleral exoplant on a model of retinal and choroidal neovascularization induced in rabbits by subretinal injection of matrigel combined with vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF). Methods: Nine New Zealand white rabbits were randomly assigned to three groups (episcleral celecoxib exoplant, intravitreal bevacizumab injection and control group)...
2018: International Journal of Retina and Vitreous
https://www.readbyqxmd.com/read/30083392/iodate-induced-toxic-retinopathy-a-case-report
#7
Y C Venu Gopal Reddy, Anuj Sharma, Adheesh P Shetty, Syed Mohideen Abdul Kader
Background: Iodine deficiency is a common preventable cause of intellectual and developmental disabilities. Iodine in the form of potassium iodate is added to the common salt under the National Iodine Deficiency Disorder Control Program in India. Overdose of iodate can lead to retinal toxicity. Case presentation: We hereby present a case of a 34 year old male patient who presented to us 10 years following iodate ingestion. There was widespread outer retinal atrophy, foveal atrophy and sub-retinal fibrosis noted on fundus evaluation...
2018: International Journal of Retina and Vitreous
https://www.readbyqxmd.com/read/30026964/acute-retinal-vein-occlusion-and-cystic-fibrosis
#8
Matthew R Starr, Suzanne M Norby, John P Scott, Sophie J Bakri
Background: The ocular manifestations of cystic fibrosis typically present with surface irritation or nyctalopia due to Vitamin A deficiency, however, there have been two previous reports of patients with cystic fibrosis that developed retinal vein occlusions. These reports hypothesized that either elevated fibrinogen levels due to chronic infections or elevated homocysteine levels have predisposed patients with cystic fibrosis to develop retinal vein occlusions. Case presentation: We present a case of a 35-year-old male with cystic fibrosis complicated by chronic sinusitis with no history of organ transplantation or chronic pulmonary infections who presented with an acute branch retinal vein occlusion in his left eye with associated macular edema...
2018: International Journal of Retina and Vitreous
https://www.readbyqxmd.com/read/30002912/idiopathic-full-thickness-macular-hole-in-a-10-year-old-girl
#9
Li-Anne S Lim, Guillermo Fernandez-Sanz, Steven Levasseur, John R Grigg, Alex P Hunyor
Background: Macular holes in children are generally associated with trauma. Case presentation: We report the first case of an idiopathic full thickness macular hole in a 10-year-old girl. 23-gauge transconjunctival pars plana vitrectomy, induction of a posterior vitreous detachment, ILM blue-assisted internal limiting membrane peel, fluid-air exchange and air-26% sulfur hexafluoride (SF6) exchange was performed with subsequent macular hole closure. Conclusion: This is the first reported case of an idiopathic full thickness macular hole in a child...
2018: International Journal of Retina and Vitreous
https://www.readbyqxmd.com/read/29992046/correction-to-the-diagnosis-and-treatment-of-primary-vitreoretinal-lymphoma-a-review
#10
Jose S Pulido, Patrick B Johnston, Grzegorz S Nowakowski, Alessia Castellino, Harish Raja
[This corrects the article DOI: 10.1186/s40942-018-0120-4.].
2018: International Journal of Retina and Vitreous
https://www.readbyqxmd.com/read/29992045/the-utility-of-ultra-widefield-fluorescein-angiography-in-pediatric-retinal-diseases
#11
REVIEW
Charles M Calvo, Mary Elizabeth Hartnett
Background: Ultra-widefield angiography is the latest technology in the evolution of fundus fluorescein angiography. With the ability to capture up to 200° of the fundus in a single image, far peripheral retinal pathology can be imaged. Generally, obtaining high-quality fundus fluorescein angiography in a child without sedation in the outpatient setting is exceedingly challenging. Therefore, there are advantages to imaging platforms that can capture the peripheral retina in young children without anesthesia...
2018: International Journal of Retina and Vitreous
https://www.readbyqxmd.com/read/29951249/dexamethasone-implant-in-silicone-oil-in-vitro-behavior
#12
Erick Omar Flores-Villalobos, J Abel Ramírez-Estudillo, Atzin Robles-Contreras, Jacqueline L Oliva-Ramírez
Background: To determine the effect of the silicone on the dexamethasone intravitreal implant. Methods: Basic, experimental, prospective and transversal study performed at the hospital "Nuestra Señora de la Luz" in Mexico City. One dexamethasone implant was placed in a test tube with 4 mL of each tamponade medium: 1000cS, 5000cS and heavy silicone oil; basic saline solution was used as the control medium. Photographs were taken weekly for 12 months...
2018: International Journal of Retina and Vitreous
https://www.readbyqxmd.com/read/29942651/gamma-knife-radiosurgery-for-locally-recurrent-choroidal-melanoma-following-plaque-radiotherapy
#13
Osama A Sorour, John E Mignano, Jay S Duker
Background: For the majority of eyes with choroidal melanoma, radiation therapy is the treatment of choice. Local recurrence after radiation therapy can occur, however, and when it does, salvaging the globe with useful vision is atypical. Case presentation: We report a case of late, local failure 7 years following previous brachytherapy successfully managed with Gamma Knife radiosurgery (GKR). With 3 years of follow up after GKR, the visual acuity is 20/20 and there is no evidence of systemic metastases...
2018: International Journal of Retina and Vitreous
https://www.readbyqxmd.com/read/29881640/incidence-and-risk-factors-for-retinopathy-of-prematurity-a-retrospective-cohort-study
#14
André Moraes Freitas, Ricardo Mörschbächer, Mariana R Thorell, Ernani Luis Rhoden
Background and objectives: Advances in neonatal care promoted increased survival rates of preterm infants, with a consequent increase in the number of children affected by retinopathy of prematurity (ROP). This study estimates the incidence of ROP and evaluates potential risk factors associated. Methods: A retrospective cohort study of preterm infants born in a tertiary neonatal intensive care unit was conducted from March 2005 to August 2015. Six hundred and thirty-nine newborns were included based on the following criteria: infants born with less than 32 weeks' gestation or birth weight below 1500 g; or neonates born with 32-37 weeks' gestation or birth weight above 1500 g and any of the following associated: multiple gestation, respiratory distress syndrome, sepsis, blood transfusions or intraventricular hemorrhage...
2018: International Journal of Retina and Vitreous
https://www.readbyqxmd.com/read/29862048/re-metastatic-deaths-in-retinoblastoma-patients-treated-with-intraarterial-chemotherapy-ophthalmic-artery-chemosurgery-worldwide
#15
Sameh E Soliman, Helen Dimaras, Brenda Gallie, Furqan Shaikh
No abstract text is available yet for this article.
2018: International Journal of Retina and Vitreous
https://www.readbyqxmd.com/read/29785284/vinorelbine-induced-regression-of-a-choroidal-metastasis-from-primary-breast-carcinoma
#16
Malvika Arya, Jay S Duker
Background: Various therapeutic options exist to treat choroidal metastatic lesions. However, they are all associated with potential long-term adverse effects. This case report discusses a case of choroidal metastasis from primary breast carcinoma that regressed after single-agent chemotherapy. Case presentation: We report a case of choroidal metastasis from estrogen receptor (ER) positive breast carcinoma that became resistant to endocrine therapy. The primary malignancy was treated with surgical resection and adjuvant chemoradiation, followed by hormone therapy with various agents in combination with kinase inhibitors for ER resistance...
2018: International Journal of Retina and Vitreous
https://www.readbyqxmd.com/read/29760948/the-diagnosis-and-treatment-of-primary-vitreoretinal-lymphoma-a-review
#17
REVIEW
Jose S Pulido, Patrick B Johnston, Grzegorz S Nowakowski, Allessia Castellino, Harish Raja
Background: To describe the recent diagnostic and treatment options for the most predominant form of primary vitreoretinal lymphoma (PVRL), namely diffuse large B cell lymphoma. This is mainly based on the experience at the Mayo Clinic as well as a partial review of the literature. MYD88 L265P mutation is seen in about 80% of cases; therefore, a polymerase chain reaction for this mutation helps in making the diagnosis that has been notoriously difficult to make. Local therapy using intravitreal methotrexate and rituximab has been very helpful in the treatment of the local disease...
2018: International Journal of Retina and Vitreous
https://www.readbyqxmd.com/read/29736261/choroidal-infarction-following-ophthalmic-artery-chemotherapy
#18
Kelley J Bohm, Y Pierre Gobin, Jasmine H Francis, Gabrielle McInerney, Anahita Dabo-Trubelja, Paul H Dalecki, Brian P Marr, David H Abramson
Background: Methylenetetrahydrofolate reductase (MTHFR) genetic mutations and intra-procedural inhaled nitrous oxide (N2 O) independently increase blood levels of homocysteine, a compound associated with thrombosis. Patients with MTHFR mutations who also receive N2 O during ophthalmic artery chemotherapy (OAC) for retinoblastoma may have a heightened thrombotic risk. Case presentations: Single-center retrospective review of pediatric patients with advanced retinoblastoma who received OAC and developed choroidal infarcts...
2018: International Journal of Retina and Vitreous
https://www.readbyqxmd.com/read/29713496/choroidal-thickness-changes-measured-by-enhanced-depth-imaging-optical-coherence-tomography-in-third-trimester-pregnant-women
#19
Lorenzo Ferro Desideri, Fabio Barra, Simone Ferrero, Aldo Vagge
The aim of this article is to underline the effect of pregnancy on the variations of choroidal thickness caused by hormonal and haemodynamic changes.
2018: International Journal of Retina and Vitreous
https://www.readbyqxmd.com/read/29692926/comparison-between-optical-coherence-tomography-angiography-and-fluorescein-angiography-findings-in-retinal-vasculitis
#20
Julio Zaki Abucham-Neto, André Augusto Miranda Torricelli, Aline Cristina Fioravanti Lui, Sarah Napoli Guimarães, Heloisa Nascimento, Caio Vinícius Regatieri
Background: To describe optical coherence tomography angiography (OCT-A) findings in patients with retinal vasculitis and to compare them to current fluorescein angiography (FA) findings. Methods: This was an observational case series. Nineteen eyes in 10 patients with retinal vasculitis of various etiologies were imaged with FA (TRC-50DX, Topcon) and OCT-A (SD-OCT, Optovue). The images were reviewed and analyzed. Results: The mean age was 36 years (range 24-67 years); there were three males and seven females...
2018: International Journal of Retina and Vitreous
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