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Turkish Journal of Ophthalmology

Hazan Gül Kahraman, Feray Koç, Nazife Sefi Yurdakul
Familial exudative vitreoretinopathy (FEVR) is a rare inherited disorder of retinal angiogenesis. A 49-year-old male patient was referred to our clinic for retinal vascular occlusion. His history, clinical findings, and fundus fluorescein angiography findings were evaluated. Family members were called and eye examinations were performed. Our patient was not born preterm and he reported decreased visual acuity after a traffic accident during childhood. He had laser treatment when he was 12 years old and again 1 month before our examination...
August 2018: Turkish Journal of Ophthalmology
Ali Osman Saatçi, Ziya Ayhan, Şefik Can İpek, Meltem Söylev Bajin
Choroidal neovascular membrane (CNV) is a very rare complication in patients with sympathetic ophthalmia. We hereby report a 38-year-old man who developed a type 2 CNV in his only seeing (left) eye while under systemic steroid treatment. Systemic therapy was revised and a total of 5 intravitreal aflibercept injections (2 mg each) were administered over a period of 8 months. Good anatomic and functional outcome was noted at the last visit. Anti-vascular endothelial growth factor injection may be an important adjunct to systemic therapy in eyes with with sympathetic ophthalmia-associated CNV...
August 2018: Turkish Journal of Ophthalmology
Müge Çoban Karataş, Merih Soylu
In this case report, we presented a patient with visual deterioration as a result of papillophlebitis in the right eye who was later diagnosed with Guillain-Barré syndrome (GBS). Upon systemic and laboratory work-up to determine the etiology of papillophlebitis, the diagnosis of GBS was made and treatment was initiated immediately. The ocular and systemic symptoms resolved quickly after starting intravenous immunoglobulin therapy. We present this case to emphasize the importance of etiological diagnosis in papillophlebitis and the unusual presentation of GBS...
August 2018: Turkish Journal of Ophthalmology
Burak Tanyıldız, Gizem Doğan, Nilüfer Zorlutuna Kaymak, Mehmet Engin Tezcan, Ahmet Kasım Kılıç, Sevda Şener Cömert, Aysu Karatay Arsan
In this study, we present a case of bilateral optic neuropathy and macular ischemia in the right eye associated with neurosarcoidosis. A 26-year-old woman presented to our clinic with complaints of bilateral blurred vision. Bilateral granulomatous anterior uveitis, vitritis, optic neuropathy, and macular ischemia were detected in the right eye in slit-lamp examination. She also reported complaints of fever, weakness, sweating, arthralgia, and headache for 2 months. She was referred to the pulmonary diseases unit of our hospital due to hilar lymphadenopathy seen in her chest x-ray, and biopsies were taken for diagnostic purposes...
August 2018: Turkish Journal of Ophthalmology
Gábor Holló
Optical coherence tomography angiography (OCTA) comprises different OCT-based technologies developed for non-invasive assessment and measurement of optic nerve head and retinal perfusion. Currently the most clinically established approach is based on the split spectrum amplitude decorrelation algorithm, which detects moving red blood cells and eliminates all other information. The two main clinical fields in which OCTA offers clinically useful information are investigation of the macular retina (e.g. in macular degeneration and diabetic macular disease) and glaucoma...
August 2018: Turkish Journal of Ophthalmology
Mustafa Şahiner, Dilek Bahar, Ayşe Öner, Zeynep Burçin Gönen, Metin Ünlü, Duygu Gülmez Sevim, Çağatay Karaca, Galip Ertuğrul Mirza
Objectives: To assess the effects of anti-vascular endothelial growth factor (VEGF) drugs on retinal pigment epithelium cell culture. Materials and Methods: Aflibercept (0.5 mg/mL), bevacizumab (0.3125 mg/mL), and ranibizumab (0.125 mg/mL) were applied to retinal pigment epithelium cell cultures isolated from the enucleated eyes of New Zealand white rabbits. Viability, apoptosis, proliferation, and senescence of the cells were evaluated in control and drug-treated cultures at the end of 72 hours...
August 2018: Turkish Journal of Ophthalmology
Nefati Kıylıoğlu, Mahmut Alp Kılıç, Tolga Kocatürk, Seyhan Bahar Özkan, Mehmet Bilgen
Objectives: This paper presents the design and construction of a viable pupillometer system and demonstrates its merits with extensive validation tests. Materials and Methods: A web camera was modified by removing its infrared filter and mounted on a chin rest. Light emitting diodes (LEDs) operating at infrared and visible spectra were integrated to provide background and light stimulus, respectively. The LEDs were controlled by a microprocessor board. Stimulation was presented using a periodic paradigm with variable period and duty cycle...
August 2018: Turkish Journal of Ophthalmology
Zerrin Tuncer, Mitat Altuğ
Objectives: To determine interindividual variability in the angle between the anatomic axis connecting the fovea and optic disc center and the horizontal meridian using spectral domain optical coherence tomography (OCT). Materials and Methods: A total of 260 eyes of 133 subjects (81 women, 52 men) with glaucoma or suspected glaucoma were included in the study retrospectively. Fovea-disc angle (FoDi angle) measurements, determined as the angle between the horizontal meridian passing through the Bruch's membrane opening (BMO) center and the line connecting the fovea and BMO center, were recorded from spectral domain-OCT scans performed by the same investigator...
August 2018: Turkish Journal of Ophthalmology
Hamidu Gobeka, Özlem Barut Selver, Melis Palamar Onay, Sait Eğrilmez, Ayşe Yağcı
Objectives: To investigate the corneal biomechanical properties of keratoconic eyes following penetrating keratoplasty (PKP). Materials and Methods: Thirty-five patients (70 eyes) were enrolled to this prospective study. Operated and contralateral keratoconic eyes were defined as Group 1 and 2, respectively. All patients underwent ophthalmological examination and measurements of corneal biomechanical properties by Ocular Response Analyzer (ORA), intraocular pressure (IOP) by Goldmann applanation tonometry, and central corneal thickness (CCT) by Pentacam...
August 2018: Turkish Journal of Ophthalmology
Cemal Çavdarlı, Pınar Topçu-Yılmaz
Objectives: To assess the long-term effects of soft contact lenses (SCL) on the cornea and anterior chamber by topography. Materials and Methods: Thirty-nine eyes of 22 healthy patients were included in this prospective study. Changes in corneal and anterior chamber parameters before and after 12 months of daily SCL use (Air Optix Aqua, Air Optix Aqua for Astigmatism, Acuvue Oasys and Acuvue Oasys for Astigmatism) were evaluated with Pentacam (Oculus, Germany). Results: Best corrected visual acuity with toric SCL was significantly better compared to spectacles in the toric SCL group (0...
August 2018: Turkish Journal of Ophthalmology
Raciha Beril Küçümen, Berna Şahan, Canan Aslı Yıldırım, Ferda Çiftçi
Objectives: To evaluate corneal biomechanics before and after collagen crosslinking (CXL) in patients with progressive keratoconus. Materials and Methods: In this prospective study, CXL was performed under topical anesthesia after removal of the epithelium (epi-off technique) by applying ultraviolet A (UVA) light at a wavelength of 365 nm and power of 3 mW/cm2 or 5.4 joule/cm2. Isoosmolar 0.1% riboflavin solution was administered before and during UVA irradiation...
August 2018: Turkish Journal of Ophthalmology
Erdoğan Yaşar, Deniz Öztürk Kara, Nilgün Yıldırım
A 21-year-old male patient with no history of systemic disease or drug use presented to our clinic with redness and pain in the right eye. Best corrected visual acuity was 20/20 in both eyes. Inflamed pinguecula was observed on slit-lamp examination and the patient was prescribed ophthalmic nepafenac eye drops. After instilling the drops that day and the next day, the patient presented again due to pruritus and rash. Upon consultation with the dermatology department, the patient was diagnosed with drug-induced allergic urticaria and the nepafenac drops were discontinued...
June 2018: Turkish Journal of Ophthalmology
Selma Özbek-Uzman, Ayşe Burcu, Züleyha Yalnız-Akkaya, Evin Şingar-Özdemir, Firdevs Örnek
Infectious keratitis after corneal lamellar surgery is a rare complication. In this report, we present unexpected complications after crescentic lamellar wedge resection (CLWR) and their treatment in a patient with pellucid marginal degeneration. A 42-year-old male patient developed fungal keratitis due to Candida parapsilosis in the late postoperative period after CLWR. Infection was controlled with medical treatment. However, recurrent intraocular infections and cataract formation occurred, probably due to capsular damage and inoculation of microorganisms into the crystalline lens during antifungal drug injection...
June 2018: Turkish Journal of Ophthalmology
Şerife Bayraktar, Samuray Tuncer, Cahit Özgün, Gönül Peksayar, Rejin Kebudi
Objectives: To investigate visual outcomes, surgical complications and tumor recurrence among children with retinoblastoma undergoing phacoemulsification and posterior chamber intraocular lens (PCIOL) implantation for radiation-induced cataract secondary to external beam radiotherapy. Materials and Methods: The medical records of all patients treated by phacoemulsification and PCIOL implantation for radiation-induced cataract after external beam radiotherapy for retinoblastoma at a single institution between 1980 and 2014 were reviewed retrospectively...
June 2018: Turkish Journal of Ophthalmology
Ayşe Bozkurt Oflaz, Bengü Ekinci Köktekir, Süleyman Okudan
Objectives: To evaluate the correlation of cataract surgical simulator and real-life surgical experience and its contribution to surgical training. Materials and Methods: Sixteen doctors in our department were divided into three groups based on their surgical experience. After being familiarized with the device, the participants were evaluated while performing the navigation, forceps, bimanual practice, anti-tremor and capsulorhexis stages. The capsulorhexis stage was repeated five times...
June 2018: Turkish Journal of Ophthalmology
Tuna Çelik, Feyza Bilen, Fatime Nilüfer Yalçındağ, Huban Atilla
Optical coherence tomography angiography (OCTA) is a non-invasive alternative method used in the diagnosis and follow-up of acute branch retinal artery occlusion to show changes secondary to ischemia. We report a case with acute branch retinal artery occlusion. A 52-year-old man presented with a complaint of sudden-onset visual loss in the right lower quadrant of the left eye for the previous three days. Best-corrected visual acuity was 0.4 temporally. Inferonasal visual field deficit was detected with confrontation...
June 2018: Turkish Journal of Ophthalmology
Zeynep Demirtaş, Gökçe Dağtekin, Muhammed Fatih Önsüz, Aziz Soysal, Nilgün Yıldırım, Selma Metintaş
Objectives: The present study was conducted to develop an instrument for measuring adults' glaucoma knowledge levels and to establish the instrument's validity and reliability. Materials and Methods: The study group consisted of 811 persons aged 40-80 years who presented to primary health care institutions and did not have a glaucoma diagnosis. A 27-item questionnaire measuring level of glaucoma knowledge was created by the study team. Following expert consultation, it was structurally evaluated...
June 2018: Turkish Journal of Ophthalmology
Samira Huseynli, Farah Abdulaliyeva
Objectives: To evaluate tomographic and topographic parameters in subclinical and clinical keratoconus eyes by comparing them with normal eyes in a young Caucasian population. Materials and Methods: This cross-sectional study included 88 normal eyes (control group), bilateral data from the preclinical stage of 24 progressive keratoconus eyes (bilateral subclinical keratoconus group), 40 fellow eyes of patients with unilateral keratoconus (fellow eyes group) and 97 eyes with mild keratoconus (clinical keratoconus group)...
June 2018: Turkish Journal of Ophthalmology
Türkan Eldem, Bora Eldem
Due to recent advances in science and technology, when the products used in therapy are examined, ophthalmology has a priority in terms of research and development, preclinical and clinical studies of innovative drugs, medical devices and drug-medical device combination products. Liposomes, micelles, nanoemulsions, nanoparticles with colloidal structures and intraocular implants as sustained-release drug delivery systems have been developed to overcome the barriers to ocular applications, increase absorption, decrease metabolism and elimination and increase the residence time in ocular tissues and compartments...
June 2018: Turkish Journal of Ophthalmology
Mehmet Giray Ersöz, Duygu Kunak Mart, Leyla Hazar, Emre Ayıntap, İrfan Botan Güneş, Hakkı Özgür Konya
Objectives: To analyze optic nerve head images of pseudoexfoliative glaucoma (PXG) patients and healthy volunteers obtained with enhanced depth imaging spectral domain-optical coherence tomography (SD-OCT). Materials and Methods: Seventy patients with PXG and 68 age- and gender-matched healthy subjects were included in this prospective study. The prelaminar tissue and lamina cribrosa were imaged using spectralis OCT with the enhanced depth imaging technique. PXG disease stage was determined with visual field to evaluate relationships between prelaminar tissue thickness (PTT), lamina cribrosa thickness (LT) and disease severity...
June 2018: Turkish Journal of Ophthalmology
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