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Open Access Rheumatology: Research and Reviews

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https://www.readbyqxmd.com/read/27920585/medical-expert-testimony-as-conflict-of-interest-regarding-the-onset-of-rheumatoid-arthritis-following-trauma
#1
COMMENT
David D Sherry
No abstract text is available yet for this article.
2016: Open Access Rheumatology: Research and Reviews
https://www.readbyqxmd.com/read/27895519/portal-hypertension-an-uncommon-clinical-manifestation-of-takayasu-arteritis-in-a-9-year-old-child
#2
Cristina N Herrera, Javier E Tomala-Haz
Takayasu arteritis (TA) is the third most common childhood vasculitis and its clinical manifestations depend on the arteries involved. We report a case of a 9-year-old boy with multiple aneurysms in carotid and iliac arteries, subclavian and coronary arteries, and abdominal aorta. At the age of 7 years, he presented with recurrent fever and hepatosplenomegaly. An angio-computed tomography scan showed aneurysms in the left subclavian artery, abdominal aorta, and both proximal iliac arteries. He was diagnosed with TA and was treated with corticosteroids, aspirin, and enalapril...
2016: Open Access Rheumatology: Research and Reviews
https://www.readbyqxmd.com/read/27843376/anxiety-and-depression-in-patients-with-osteoarthritis-impact-and-management-challenges
#3
Anirudh Sharma, Prtha Kudesia, Qian Shi, Rajiv Gandhi
BACKGROUND: Anxiety and depression are common psychological comorbidities that impact the quality of life (QoL) of patients. In this systematic review, we 1) determined the impact of anxiety and depression on outcomes in patients with osteoarthritis (OA) and 2) summarized unique challenges these comorbidities present to current OA management. PATIENTS AND METHODS: A systematic literature search was performed using the OVID Medline and EMBASE databases until April 2016...
2016: Open Access Rheumatology: Research and Reviews
https://www.readbyqxmd.com/read/27843375/polymyalgia-rheumatica-and-cancer-risk-the-importance-of-the-diagnostic-set
#4
Ciro Manzo, Maria Natale
In the last few years, the relationship between polymyalgia rheumatica (PMR) and cancer has been considered with very different conclusions. In particular, in 2010, Ji et al examined the overall and specific cancer risks among Swedish subjects following hospitalization for PMR and giant cell arteritis and noted that the risk of cancer was highest in the first year after hospitalization (of 3941 total cancer diagnoses, 783 [19.1%] were in the first year). In 2013, Muller et al, using data from General Practice Research Database, highlighted that elderly patients with a PMR diagnosis were significantly more likely to receive a cancer diagnosis in the year after PMR diagnosis (313/667 cancer cases [69%])...
2016: Open Access Rheumatology: Research and Reviews
https://www.readbyqxmd.com/read/27843374/potential-serum-and-urine-biomarkers-in-patients-with-lupus-nephritis-and-the-unsolved-problems
#5
REVIEW
Song-Chou Hsieh, Chang-Youh Tsai, Chia-Li Yu
Lupus nephritis (LN) is one of the most frequent and serious complications in the patients with systemic lupus erythematosus. Autoimmune-mediated inflammation in both renal glomerular and tubulointerstitial tissues is the major pathological finding of LN. In clinical practice, the elevated anti-dsDNA antibody titer concomitant with reduced complement C3 and C4 levels has become the predictive and disease-activity surrogate biomarkers in LN. However, more and more evidences suggest that autoantibodies other than anti-dsDNA antibodies, such as anti-nucleosome, anti-C1q, anti-C3b, anti-cardiolipin, anti-endothelial cell, anti-ribonuclear proteins, and anti-glomerular matrix (anti-actinin) antibodies, may also involve in LN...
2016: Open Access Rheumatology: Research and Reviews
https://www.readbyqxmd.com/read/27843373/the-onset-of-rheumatoid-arthritis-following-trauma
#6
Arthur E Brawer, Noopur Goel
BACKGROUND: Rheumatoid arthritis (RA) is known to have many predisposing factors. OBJECTIVE: We studied individuals whose RA was initiated by physical injuries. PATIENTS AND METHODS: Sixty patients (43 females), previously well, developed RA following trauma. No other known environmental or familial influences were present. Fourteen sustained a fracture; of the 46 who did not, 36 sustained multiple injuries that in part involved the axial skeleton...
2016: Open Access Rheumatology: Research and Reviews
https://www.readbyqxmd.com/read/27843372/wissler-fanconi-syndrome-and-related-diagnoses-a-case-report
#7
Mustafa Q Albustani, Robert F Howard
INTRODUCTION: Wissler-Fanconi syndrome is a rare rheumatic syndrome that was first described during the 1940s in Europe. Since then, many papers have been written that cover all aspects of this syndrome, most of which are in French and German language, with only a very few in English (none of them recent). We report here a case that fulfils the criteria for Wissler-Fanconi syndrome. Under the more general descriptive umbrella of Wissler-Fanconi syndrome, our patient also fulfils the Modified Jones criteria, and the 2010 American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) classification criteria for rheumatoid arthritis, and was interpreted by other internists and another rheumatologist as fulfilling the Yamaguchi criteria for adult onset Still's disease...
2016: Open Access Rheumatol
https://www.readbyqxmd.com/read/27843371/the-family-journey-to-diagnosis-with-systemic-juvenile-idiopathic-arthritis-a-cross-sectional-study-of-the-changing-social-media-presence
#8
Renee F Modica, Kathleen Graham Lomax, Pamela Batzel, Leah Shapardanis, Kimberly Compton Katzer, Melissa E Elder
BACKGROUND: Children with systemic juvenile idiopathic arthritis (SJIA) often encounter a delay between symptom onset and disease diagnosis, partly due to the broad differential of fever and lack of symptom recognition by providers. Families often seek multiple medical opinions and post on social media about their frustrations. This linguistic analysis observed the changing language patterns and social media posting behaviors of parents in the time leading to, during, and after SJIA diagnosis...
2016: Open Access Rheumatology: Research and Reviews
https://www.readbyqxmd.com/read/27843370/rheumatoid-arthritis-in-patients-with-hiv-management-challenges
#9
REVIEW
Matthew B Carroll, Joshua H Fields, Philip G Clerc
Over the past few decades, HIV has been transformed from a once-uniformly fatal disease to now a manageable but complex multisystem illness. Before highly active antiretroviral therapy (HAART), reports suggested that HIV-infected patients with rheumatoid arthritis (RA) would experience remission of their disease. It has now become clear that RA can develop in HIV-infected patients at any time, independent of HAART. Choosing the right medication to treat symptoms related to RA while avoiding excess weakening of the immune system remains a clinical challenge...
2016: Open Access Rheumatology: Research and Reviews
https://www.readbyqxmd.com/read/27843369/polymyalgia-rheumatica-observations-of-disease-evolution-without-corticosteroid-treatment
#10
Arthur E Brawer
OBJECTIVES: The diagnostic diversity of polymyalgia rheumatica (PMR) can easily be obscured by the widespread use of corticosteroids (CSs) early in the disease course. This study observed the course of PMR without CSs and determined whether alternative medication could be useful. METHODS: Seventy patients with new-onset PMR comprised phase 1. Eight were removed with specific diagnoses (four with giant cell arteritis [GCA]). The remaining 62 were treated with nonsteroidal anti-inflammatory drugs (NSAIDs) alone until enough time had elapsed to ascertain whether their PMR had evolved into another rheumatologic inflammatory condition...
2016: Open Access Rheumatol
https://www.readbyqxmd.com/read/27843368/an-evidence-based-review-of-certolizumab-pegol-in-the-treatment-of-active-psoriatic-arthritis-place-in-therapy
#11
REVIEW
María Laura Acosta-Felquer, Javier Rosa, Enrique R Soriano
Certolizumab pegol (CZP) is a pegylated humanized tumor necrosis factor-α inhibitor (TNFi) approved for the treatment of psoriatic arthritis (PsA) in Europe, the USA, and Latin American countries. CZP neutralizes TNF-α at its soluble and membrane portions. Due to the lack of Fc region, it does not induce complement or antibody-dependent cytotoxicity in vitro, unlike other TNFi. RAPID-PsA study, the only randomized clinical trial performed in PsA, is a Phase III clinical trial conducted in 409 PsA patients during 24 weeks...
2016: Open Access Rheumatology: Research and Reviews
https://www.readbyqxmd.com/read/27843367/management-of-rheumatoid-arthritis-during-pregnancy-challenges-and-solutions
#12
REVIEW
Megan L Krause, Ashima Makol
Rheumatoid arthritis, a chronic inflammatory autoimmune disease with significant physical disability, affects women three times more frequently than men, often in their childbearing years. Parenthood decisions can be challenging, often affected by perceptions of their disease state, health care needs, and complex pharmacological treatments. Many women struggle to find adequate information to guide them on pregnancy planning, lactation, and early parenting in relation to their chronic condition. The expanded availability and choice of pharmacotherapies have supported optimal disease control prior to conception and enhanced physical capabilities for women to successfully overcome the challenges of raising children but require a detailed understanding of their risks and safety in the setting of pregnancy and breastfeeding...
2016: Open Access Rheumatology: Research and Reviews
https://www.readbyqxmd.com/read/27843366/adult-onset-still-s-disease-current-challenges-and-future-prospects
#13
REVIEW
Mariam Siddiqui, Michael S Putman, Anisha B Dua
Adult-onset Still's disease (AOSD) - a multi-systemic inflammatory condition characterized by high fevers, polyarthritis, an evanescent rash, and pharyngitis - has been a challenging condition to diagnose expediently and treat effectively. Questions remain regarding the underlying pathophysiology and etiology of AOSD. Pathognomonic diagnostic tests and reliable biomarkers remain undiscovered. Over the past decade, important progress has been made. Diagnostic criteria employing glycosylated ferritin have improved specificity...
2016: Open Access Rheumatology: Research and Reviews
https://www.readbyqxmd.com/read/27843365/a-systematic-review-to-evaluate-exercise-for-anterior-cruciate-ligament-injuries-does-this-approach-reduce-the-incidence-of-knee-osteoarthritis
#14
REVIEW
Koji J Duncan, Jaclyn N Chopp-Hurley, Monica R Maly
PURPOSE: Among a variety of conservative and surgical options to treat anterior cruciate ligament (ACL) injuries, we do not understand which options could potentially prevent knee osteoarthritis (OA). The aim of this systematic review was to examine the evidence pertaining to exercise treatment of ACL injuries in the context of knee OA. METHODS: Medline, Embase, CINAHL, PubMed, and PEDro (Physiotherapy Evidence Database) databases were systematically searched using keywords encompassed within four primary key terms: knee, osteoarthritis, anterior cruciate ligament, and exercise...
2016: Open Access Rheumatology: Research and Reviews
https://www.readbyqxmd.com/read/27790047/the-use-of-administrative-health-care-databases-to-identify-patients-with-rheumatoid-arthritis
#15
John G Hanly, Kara Thompson, Chris Skedgel
OBJECTIVE: To validate and compare the decision rules to identify rheumatoid arthritis (RA) in administrative databases. METHODS: A study was performed using administrative health care data from a population of 1 million people who had access to universal health care. Information was available on hospital discharge abstracts and physician billings. RA cases in health administrative databases were matched 1:4 by age and sex to randomly selected controls without inflammatory arthritis...
2015: Open Access Rheumatology: Research and Reviews
https://www.readbyqxmd.com/read/27790046/different-t-cells-distribution-and-activation-degree-of-th17-cd4-cells-in-peripheral-blood-in-patients-with-osteoarthritis-rheumatoid-arthritis-and-healthy-donors-preliminary-results-of-the-magenta-clicao-study
#16
Alfredomaria Lurati, Antonella Laria, Arianna Gatti, Bruno Brando, Magda Scarpellini
OBJECTIVE: To determine distribution of T cells and activation degree of Th CD4+ cells in peripheral blood of patients with osteoarthritis (OA), rheumatoid arthritis (RA), and healthy donors. METHODS: Patients with established diagnosis of RA according to American College of Rheumatology/European League Against Rheumatism 2010 criteria, knee or hip OA according to American College of Rheumatology criteria, and healthy blood donor volunteers were eligible. Multi-channel flow cytometry and monoclonal antibodies against CD3, CD4, CD8, CCR6, CD38, CXCR3, and HLA DR were used to distinguish and evaluate T cells' subpopulation...
2015: Open Access Rheumatology: Research and Reviews
https://www.readbyqxmd.com/read/27790045/optimal-management-of-dactylitis-in-patients-with-psoriatic-arthritis
#17
REVIEW
Toshiyuki Yamamoto
Psoriatic arthritis (PsA) is an inflammatory arthropathy associated with cutaneous psoriasis, which is currently classified as a seronegative spondyloarthropathy. The presence of cutaneous psoriasis is important for correct and early diagnosis of PsA, because the onset of cutaneous lesions usually precedes the appearance of joint manifestation. Thus, dermatologists are able to detect the condition at its inception. PsA has several unique characteristics such as enthesopathy, dactylitis, and abnormal bone remodeling...
2015: Open Access Rheumatology: Research and Reviews
https://www.readbyqxmd.com/read/27790044/the-patient-perspective-arthritis-care-provided-by-advanced-clinician-practitioner-in-arthritis-care-program-trained-clinicians
#18
Kelly Warmington, Carol A Kennedy, Katie Lundon, Leslie J Soever, Sydney C Brooks, Laura A Passalent, Rachel Shupak, Rayfel Schneider
OBJECTIVE: To assess patient satisfaction with the arthritis care services provided by graduates of the Advanced Clinician Practitioner in Arthritis Care (ACPAC) program. MATERIALS AND METHODS: This was a cross-sectional evaluation using a self-report questionnaire for data collection. Participants completed the Patient-Doctor Interaction Scale, modified to capture patient-practitioner interactions. Participants completed selected items from the Group Health Association of America's Consumer Satisfaction Survey, and items capturing quality of care, appropriateness of wait times, and a comparison of extended-role practitioner (ERP) services with previously received arthritis care...
2015: Open Access Rheumatology: Research and Reviews
https://www.readbyqxmd.com/read/27790043/new-developments-in-the-treatment-of-osteoarthritis-focus-on-biologic-agents
#19
REVIEW
Jose Ignacio Torrero, Carlos Martínez
Osteoarthritis (OA) is one of the most common diseases around the world. Medical, social, and financial consequences oblige clinicians, surgeons, and researchers to focus on finding the best treatment option, to eradicate and stop this degenerative joint disease, in order to avoid surgical options which in many instances are over-indicated. Noninvasive treatments, such as anti-inflammatory drugs, physiotherapy, orthotic devices, dietary supplements, have demonstrated lack of effectiveness. The possibility to perform intra-articular injections with hyaluronic acid, corticosteroids, or the newest but criticized treatment based on platelet-rich plasma (PRP) has changed the management of OA disease...
2015: Open Access Rheumatology: Research and Reviews
https://www.readbyqxmd.com/read/27790042/treatment-of-systemic-onset-juvenile-arthritis-with-canakinumab
#20
REVIEW
Joachim Peitz, Gerd Horneff
Treatment of systemic-onset juvenile idiopathic arthritis is challenging, but the availability of cytokine antagonists targeting interleukin-1 and interleukin-6 have markedly advanced the therapeutic options. In this review, we focus on the current experience with canakinumab, an interleukin-1 monoclonal human antibody for the treatment of systemic-onset juvenile idiopathic arthritis and describe its efficacy and safety. Canakinumab is an important, safe, and valid drug in the treatment of systemic-onset juvenile idiopathic arthritis...
2015: Open Access Rheumatology: Research and Reviews
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