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European Journal of Rheumatology

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https://www.readbyqxmd.com/read/28293463/chikungunya-and-bilateral-sacroiliitis-is-there-a-link
#1
Muhammad K Nisar, Christabel Packianathan
No abstract text is available yet for this article.
March 2017: European Journal of Rheumatology
https://www.readbyqxmd.com/read/28293462/heterotopic-ossification-myositis-ossificans-progressiva-a-condition-interfering-with-rheumatic-disease
#2
Gülşen Işıklı, Lütfi Akyol, Sibel Semirgin Uçak, Kerim Aslan, Metin Özgen, Mehmet Sayarlıoğlu
No abstract text is available yet for this article.
March 2017: European Journal of Rheumatology
https://www.readbyqxmd.com/read/28293461/a-rare-cause-of-cytopenia-in-a-patient-with-systemic-lupus-erythematosus-autoimmune-myelofibrosis
#3
Döndü Üsküdar Cansu, Hava Üsküdar Teke, Cengiz Korkmaz
Hematological abnormalities are very common in the course of systemic lupus erythematosus (SLE). Myelofibrosis is a bone marrow disorder in which there is excessive fibrous tissue formation in the bone marrow. Various benign and malignant disorders can cause or be associated with a diffuse increase in the bone marrow reticular tissue. Some diseases such as infections, neoplasms, and autoimmune diseases may also induce bone marrow fibrosis (secondary myelofibrosis). Cytopenia from autoimmune myelofibrosis (AIMF) in SLE is a rare condition...
March 2017: European Journal of Rheumatology
https://www.readbyqxmd.com/read/28293460/pauci-immune-lupus-nephritis-possibility-or-co-incidence
#4
Döndü Üsküdar Cansu, Gökhan Temiz, Mustafa F Açıkalın, Cengiz Korkmaz
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized with immune complex formation and renal involvement of lupus and may include several kinds of pathological conditions, but mostly, it is associated with immune complex-induced glomerular disease. Pauci-immune lupus nephritis is a very rare condition. We describe a 45-year-old female patient with pauci-immune crescentic necrotizing lupus nephritis and briefly discuss the possible mechanism and pathogenesis.
March 2017: European Journal of Rheumatology
https://www.readbyqxmd.com/read/28293459/refractory-optic-perineuritis-due-to-granulomatosis-with-polyangiitis-successfully-treated-with-methotrexate-and-mycophenolate-mofetil-combination-therapy
#5
Yoshitaka Kimura, Kurumi Asako, Hirotoshi Kikuchi, Hajime Kono
Optic perineuritis is an uncommon inflammatory disorder of the optic sheath that causes visual loss or eye pain. There are few case reports of optic perineuritis associated with granulomatosis with polyangiitis. Herein we report the case of a 37-year-old male with granulomatosis with polyangiitis and who presented with headache, blurred vision in the right eye, diplopia, and numbness in the right forehead. Brain magnetic resonance images (MRI) findings revealed hypertrophic pachymeningitis and refractory optic perineuritis...
March 2017: European Journal of Rheumatology
https://www.readbyqxmd.com/read/28293458/the-novel-use-of-combined-il-1-and-il-6-inhibition-in-a-patient-with-severe-aggressive-erosive-systemic-onset-juvenile-idiopathic-arthritis
#6
Martin Lee, John Isaacs
Systemic-onset juvenile idiopathic arthritis (SoJIA) is a form of juvenile idiopathic arthritis (JIA) that typically presents with prominent systemic features and accounts for approximately 10-15% of children with JIA. Pro-inflammatory cytokine pathways are thought to be involved in its pathogenesis, including interleukin-1 (IL-1) and interleukin-6 (IL-6), and laboratory tests demonstrate a prominent inflammatory response with high CRP and ferritin levels. We present a case of severe, aggressive, erosive SoJIA in a 17-year-old male resistant to multiple biologic therapies treated with a novel combination of IL-1 and IL-6 blockade along with subcutaneous methotrexate...
March 2017: European Journal of Rheumatology
https://www.readbyqxmd.com/read/28293457/anakinra-use-during-pregnancy-report-of-a-case-with-familial-mediterranean-fever-and-infertility
#7
Ufuk İlgen, Orhan Küçükşahin
Familial Mediterranean fever (FMF), affecting people of Mediterranean origin, is an endemic and sometimes problematic disease because of colchicine resistance/intolerance, with relative lack of treatment alternatives, and disease- or treatment-related issues, such as subfertility. Anakinra, being a rational and effective treatment alternative, has no conclusive human pregnancy data. Here we report a case of FMF with infertility who became pregnant with in vitro fertilization (IVF) under treatment with anakinra, along with the pregnancy outcome...
March 2017: European Journal of Rheumatology
https://www.readbyqxmd.com/read/28293456/acute-digital-ischemia-a-rare-presentation-of-antisynthetase-syndrome
#8
Jin Ei Chan, Sandeep Palakodeti, Matthew J Koster
Antisynthetase syndrome (ASS) is recognized as a subgroup of idiopathic inflammatory myopathies (IIMs). It is associated with autoantibodies directed against aminoacyl-transfer ribonucleic acid (tRNA) synthetase enzymes. We report the first case of anti-PL-7/anti-SSA 52kD ASS presenting as acute digital ischemia, an association not described previously. Occlusive vasculopathy is a rare but serious manifestation that can be seen at presentation in patients with ASS and may herald the onset of severe interstitial lung disease (ILD)...
March 2017: European Journal of Rheumatology
https://www.readbyqxmd.com/read/28293455/viscosupplementation-of-the-knee-three-cases-of-acute-pseudoseptic-arthritis-with-painful-and-irritating-complications-and-a-literature-review
#9
Murat Aydın, Murat Arıkan, Güray Toğral, Onur Varış, Güle Aydın
Acute pseudoseptic arthritis is a very rare complication that is associated with intra-articular hyaluronic acid injections, which normally involve minimal risk. The most common adverse events that are caused by hyaluronic acid injections are inflammatory reactions or flares at the injection site. In this study, we described three cases of acute pseudoseptic arthritis that was caused by hyaluronic acid; the symptoms in these cases were reminiscent of acute septic arthritis. Moreover, we performed a literature review on pseudoseptic arthritis following hyaluronic acid injections to determine the manner in which this condition can be described, diagnosed, and treated...
March 2017: European Journal of Rheumatology
https://www.readbyqxmd.com/read/28293454/can-rheumatoid-vasculitis-predate-a-diagnosis-of-rheumatoid-arthritis
#10
Sarah Sacks, Alan Steuer
We report regarding a male patient who presented with a systemic vasculitis that was consistent with a diagnosis of polyarteritis nodosa. At presentation, he had no features of inflammatory arthritis but had a high rheumatoid factor titer and low C4 level. Withdrawal of immunosuppression after 6 years resulted in the development of classical rheumatoid arthritis (RA). This case supports previous reports that revealed that vasculitis may predate the development or occur very early in the course of articular RA...
March 2017: European Journal of Rheumatology
https://www.readbyqxmd.com/read/28293453/an-overview-and-management-of-osteoporosis
#11
REVIEW
Tümay Sözen, Lale Özışık, Nursel Çalık Başaran
Osteoporosis -related to various factors including menopause and aging- is the most common chronic metabolic bone disease, which is characterized by increased bone fragility. Although it is seen in all age groups, gender, and races, it is more common in Caucasians (white race), older people, and women. With an aging population and longer life span, osteoporosis is increasingly becoming a global epidemic. Currently, it has been estimated that more than 200 million people are suffering from osteoporosis. According to recent statistics from the International Osteoporosis Foundation, worldwide, 1 in 3 women over the age of 50 years and 1 in 5 men will experience osteoporotic fractures in their lifetime...
March 2017: European Journal of Rheumatology
https://www.readbyqxmd.com/read/28293452/prevalence-of-metabolic-syndrome-and-degree-of-cardiovascular-disease-risk-in-patients-with-psoriatic-arthritis
#12
Sıdıka Gülkan Özkan, Hatice Yazısız, Ahmet Behlül, Yüksel Aslı Gökbelen, Fatih Borlu, Veli Yazısız
OBJECTIVE: The aim of this study was to identify the prevalence of metabolic syndrome (MetS) and degree of cardiovascular disease (CVD) risk in patients with psoriatic arthritis (PsA). MATERIAL AND METHODS: We performed a cross-sectional study on 102 adult patients with PsA and a control group of 102 patients with rheumatoid arthritis (RA). MetS was diagnosed according to the National Cholesterol Education Program Adult Treatment Panel III (NCEP-ATP III) and International Diabetes Federation (IDF) criteria...
March 2017: European Journal of Rheumatology
https://www.readbyqxmd.com/read/28293451/investigation-of-joint-hypermobility-in-individuals-with-hyperbilirubinemia
#13
Muhammet Çınar, Mustafa Çakar, Kadir Öztürk, İbrahim Çetindağlı, Sedat Yılmaz, Ayhan Dinç
OBJECTIVE: Benign joint hypermobility syndrome refers to hypermobile individuals with musculoskeletal symptoms in the absence of any systemic rheumatic disease; its prevalence is approximately 0.5%. In animal studies, bilirubin has been shown to reduce fibrosis induced by bleomycin. It has been suggested that bilirubin leads to hypermobility that affects the structure or function of collagen. In addition, our observation is that hypermobility occurs more often in patients with indirect hyperbilirubinemia...
March 2017: European Journal of Rheumatology
https://www.readbyqxmd.com/read/28293450/il-17a-levels-in-systemic-lupus-erythematosus-associated-with-inflammatory-markers-and-lower-rates-of-malignancy-and-heart-damage-evidence-for-a-dual-role
#14
Warren Raymond, Gro Ostli-Eilertsen, Sheynae Griffiths, Johannes Nossent
OBJECTIVE: The interleukin 17 (IL-17) cytokine family is involved in a number of chronic inflammatory diseases. In spite of contradictory findings and a lack of causality in clinical studies, IL-17 inhibition for systemic lupus erythematosus (SLE) has regained attention as a potential therapeutic pathway, after demonstrating disease-modifying capabilities in ankylosing spondylitis. We investigated the clinical associations of interleukin 17 A (IL-17A) in patients with SLE. MATERIAL AND METHODS: A cross-sectional study was performed involving SLE patients (n=102; age: 49 years; 86% female) recruited from a regional registry...
March 2017: European Journal of Rheumatology
https://www.readbyqxmd.com/read/28293449/subclinical-enthesopathy-in-patients-with-psoriasis-and-its-association-with-other-disease-parameters-a-power-doppler-ultrasonographic-study
#15
Abdelhafeez Moshrif, Ahmed Mosallam, Essam Elden M Mohamed, Wesam Gouda, Mostafa Doma
OBJECTIVE: This study aimed to determine the prevalence of subclinical enthesopathy in patients with psoriasis using power Doppler ultrasonography (PDUS) and its association with other disease parameters. MATERIAL AND METHODS: A total of 50 patients with psoriasis (31 females) aged 19-70 years underwent a thorough clinical examination that included assessment of body mass index (BMI) and psoriasis area and severity index (PASI) score. Measurements of inflammatory markers, C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), serum uric acid, and plain radiography of the heels, knees, and sacroiliac joints were performed for all patients...
March 2017: European Journal of Rheumatology
https://www.readbyqxmd.com/read/28293448/serum-calreticulin-as-a-novel-biomarker-of-juvenile-idiopathic-arthritis-disease-activity
#16
Nashwa Ismail Hashaad, Rasha Mohamed Fawzy, Abeer Ahmed Abo Elazem, Mohamed Ibrahim Youssef
OBJECTIVE: This study aimed to investigate the relations between calreticulin (CRT) serum level and both disease activity and severity parameters in juvenile idiopathic arthritis (JIA). MATERIAL AND METHODS: In this study, 60 children with JIA and 50 age-and-sex-matched healthy subjects were enrolled. The assessment of the disease activity was done using juvenile arthritis disease activity score 27 (JADAS-27). The assessment of disease severity was done via gray-scale ultrasonography (US) and power Doppler US (PDUS)...
March 2017: European Journal of Rheumatology
https://www.readbyqxmd.com/read/28293447/efficacy-and-safety-of-aceclofenac-in-osteoarthritis-a-meta-analysis-of-randomized-controlled-trials
#17
Parvati B Patel, Tejas K Patel
OBJECTIVE: To analyze the effects on pain, function, and safety of aceclofenac compared with other nonsteroidal anti-inflammatory drugs (NSAIDs) or pain relief medications in patients with osteoarthritis. MATERIAL AND METHODS: Two investigators independently searched the database. We included randomized controlled trials evaluating efficacy and/or safety of aceclofenac compared with control interventions (NSAIDs or acetaminophen) in patients with osteoarthritis...
March 2017: European Journal of Rheumatology
https://www.readbyqxmd.com/read/28293446/real-life-experience-of-using-conventional-disease-modifying-anti-rheumatic-drugs-dmards-in-psoriatic-arthritis-psa-retrospective-analysis-of-the-efficacy-of-methotrexate-sulfasalazine-and-leflunomide-in-psa-in-comparison-to-spondyloarthritides-other-than-psa
#18
Euthalia Roussou, Aicha Bouraoui
OBJECTIVE: With the aim of assessing the response to treatment with conventional disease-modifying anti-rheumatic drugs (DMARDs) used in patients with psoriatic arthritis (PsA), data on methotrexate, sulfasalazine (SSZ), and leflunomide were analyzed from baseline and subsequent follow-up (FU) questionnaires completed by patients with either PsA or other spondyloarthritides (SpAs). MATERIAL AND METHODS: A single-center real-life retrospective analysis was performed by obtaining clinical data via questionnaires administered before and after treatment...
March 2017: European Journal of Rheumatology
https://www.readbyqxmd.com/read/28149667/scleredema-of-buschke
#19
Rajaie Namas, Ambreen Ashraf
No abstract text is available yet for this article.
December 2016: European Journal of Rheumatology
https://www.readbyqxmd.com/read/28149666/a-case-of-central-nervous-system-nocardiosis-in-a-patient-with-lupus-treated-with-belimumab
#20
Richard Hc Lai, Deborah Kim, Florina Constantinescu
Belimumab was approved by the United States Food and Drug Administration in March 2011 as the first biological agent for treating active systemic lupus erythematosus (SLE). To the best of our knowledge, this is the first case report regarding a patient with SLE treated with belimumab who was diagnosed with central nervous system nocardiosis.
December 2016: European Journal of Rheumatology
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