journal
https://read.qxmd.com/read/38481497/autoimmune-phenomenon-associated-with-posttransplant-lymphoproliferative-disorder
#21
Pierre Isnard, Tony Huynh, Ludovic Lhermitte, Olivier Hermine, Eric Thervet, Thierry Jo Molina
No abstract text is available yet for this article.
March 2024: KI Reports
https://read.qxmd.com/read/38481496/baseline-racial-and-ethnic-differences-in-access-to-transplantation-in-medicare-s-esrd-treatment-choices-payment-model
#22
JOURNAL ARTICLE
Kelsey M Drewry, Ariana N Mora, Daeho Kim, Kalli Koukounas, Adam S Wilk, Amal N Trivedi, Rachel E Patzer
No abstract text is available yet for this article.
March 2024: KI Reports
https://read.qxmd.com/read/38481495/a-prospective-study-on-complement-activation-distinguishes-focal-segmental-glomerulosclerosis-from-minimal-change-disease
#23
JOURNAL ARTICLE
Alexandra Cambier, Natacha Patey, Virginie Royal, François Gougeon, Dominique S Genest, Soumeya Brachemi, Guillaume Bollée, Clémence Merlen, Arnaud Bonnefoy, Anne-Laure Lapeyraque, Stéphan Troyanov
INTRODUCTION: Minimal change disease (MCD) and focal segmental glomerulosclerosis (FSGS) are related podocytopathies with distinct kidney outcomes. Surprisingly, elevated urinary activation fragments have been found in FSGS despite little complement deposition on immunofluorescence (IF) staining. Whether complement activation distinguishes FSGS from MCD, participating in the development of segmental lesions, remains unknown. METHODS: We performed an observational study in patients with MCD and FSGS, and proteinuria ≥1 g/g of creatinine...
March 2024: KI Reports
https://read.qxmd.com/read/38481494/improving-gender-equity-for-women-in-nephrology-a-global-perspective
#24
EDITORIAL
Sabine Karam, Urmila Anandh, Aldjia Hocine, Michelle N Rheault, Benedicte Sautenet, Maryvonne Hourmant
No abstract text is available yet for this article.
March 2024: KI Reports
https://read.qxmd.com/read/38481493/protective-effects-of-selective-mineralocorticoid-receptor-antagonist-in-alport-syndrome-on-top-of-renin-angiotensin-system-sodium-glucose-transporter-2-blockade
#25
JOURNAL ARTICLE
Zhuo-Ran Song, Yang Li, Hong Zhang, Xu-Jie Zhou
No abstract text is available yet for this article.
March 2024: KI Reports
https://read.qxmd.com/read/38481492/acute-transient-hyperglycemia-after-steroid-induction-at-transplant-strongly-predicts-new-onset-diabetes-and-recurrence-of-diabetic-nephropathy
#26
JOURNAL ARTICLE
Carlotta Federica Zizzi, Caterina Dolla, Fabrizio Fop, Alberto Mella, Michela Sandrone, Ezio Ghigo, Silvana Bertaina, Fabio Broglio, Ester Gallo, Antonella Barreca, Guglielmo Beccuti, Franco Veglio, Alberto Milan, Antonio Lavacca, Roberta Giraudi, Luigi Biancone
No abstract text is available yet for this article.
March 2024: KI Reports
https://read.qxmd.com/read/38481491/monogenic-kidney-diseases-in-kidney-transplantation
#27
REVIEW
Valentine Gillion, Arnaud Devresse, Eric Olinger, Géraldine Dahlqvist, Nathalie Demoulin, Nathalie Godefroid, Kathleen Claes, Olivier Devuyst, Nada Kanaan
Monogenic kidney diseases are involved in up to 15% of end-stage kidney diseases (ESKDs) in adults, and in 70 % of pediatric patients. When these disorders lead to kidney failure (KF), kidney transplantation (KT) is the preferred mode of replacement therapy. KT requires specific considerations depending on the nature of the genetic disorder, the potential oncological risk, the risk of recurrence in the graft, the possibility of specific complications of immunosuppression, and the issue of living donation. The availability of genetic testing should play an increasing role in the evaluation of patients or related living donor candidates before transplantation, relevant for the pretransplantation and posttransplantation management...
March 2024: KI Reports
https://read.qxmd.com/read/38481490/providing-hemodialysis-in-unstable-areas-an-assessment-and-framework-for-effective-care
#28
JOURNAL ARTICLE
Sami Alasfar, Hani Alashavi, Khaled Hajj Nasan, Abd Aljabbar Haj Mousa, Camila Polinori, Valerie Luyckx, Mohamed Sekkarie, Saleh Kaysi, Lina Murad, Gilbert M Burnham
INTRODUCTION: Providing hemodialysis to patients with kidney failure (KF) in conflict-affected areas poses a significant challenge. Achieving and sustaining reasonable quality hemodialysis operations in such regions necessitates a comprehensive approach. METHODS: In the conflict area of Northwest (NW) Syria, a 3-phase project was initiated to address the quality of hemodialysis operations. The assessment phase involved the examination of infection prevention and control (IPC) protocols, staff training, medical protocols, individualized hemodialysis prescriptions, and laboratory testing capabilities...
March 2024: KI Reports
https://read.qxmd.com/read/38481489/the-conundrum-of-alkali-therapy-in-calcium-phosphate-stone-formers
#29
Amy A Yau
No abstract text is available yet for this article.
March 2024: KI Reports
https://read.qxmd.com/read/38481488/prospective-study-of-ultrasound-markers-of-organ-congestion-in-critically-ill-patients-with-acute-kidney-injury
#30
JOURNAL ARTICLE
William Beaubien-Souligny, Laura Galarza, Brian Buchannan, Vincent I Lau, Neill K J Adhikari, Jean Deschamps, Emmanuel Charbonney, André Denault, Ron Wald
INTRODUCTION: Organ congestion may be a mediator of adverse outcomes in critically ill patients with severe acute kidney injury (AKI). The presence of abnormal venous Doppler waveforms could identify patients with clinically significant organ congestion who may benefit from a decongestive strategy. METHODS: This prospective multicenter cohort study enrolled patients with severe AKI defined as Kidney Disease: Improving Global Outcomes stage 2 or higher. Patients were not eligible if they received renal replacement therapy (RRT) for more than 72 hours at the time of screening...
March 2024: KI Reports
https://read.qxmd.com/read/38344743/implementation-of-the-ascent-trial-to-improve-transplant-waitlisting-access
#31
JOURNAL ARTICLE
Megan Urbanski, Yi-Ting Hana Lee, Cam Escoffery, Jade Buford, Laura Plantinga, Stephen O Pastan, Reem Hamoda, Emma Blythe, Rachel E Patzer
INTRODUCTION: The Allocation System for changes in Equity in Kidney Transplantation (ASCENT) study was a hybrid type 1 trial of a multicomponent intervention among 655 US dialysis facilities with low kidney transplant waitlisting to educate staff and patients about kidney allocation system (KAS) changes and increase access to and reduce racial disparities in waitlisting. Intervention components included a staff webinar, patient and staff educational videos, and facility-specific feedback reports...
February 2024: KI Reports
https://read.qxmd.com/read/38344742/kidney-diseases-associated-with-inflammatory-bowel-disease-impact%C3%A2-of-chronic-histologic-damage-treatments-and-outcomes
#32
JOURNAL ARTICLE
Federico Yandian, Fernando Caravaca-Fontán, Loren P Herrera Hernandez, Maria José Soler, Sanjeev Sethi, Fernando C Fervenza
INTRODUCTION: Kidney disease is a well-known extraintestinal manifestation (EIM) associated with inflammatory bowel disease (IBD), with a variety of underlying etiologies. However, little is known about the overall outcomes and predictors. METHODS: This is a retrospective, observational cohort study. Patients with IBD in whom a native kidney biopsy was performed at Mayo Clinic (Rochester, MN) between 1994 and 2022, were included. Demographic, clinical, and histologic characteristics of prognostic interest were collected...
February 2024: KI Reports
https://read.qxmd.com/read/38344741/influenza-vaccine-administration-and-effectiveness-among-children-and-adults-with-glomerular-disease
#33
JOURNAL ARTICLE
Dorey A Glenn, Virginia Pate, Jarcy Zee, Emmanuel B Walter, Michelle R Denburg, Susan Hogan, Ronald J Falk, Amy Mottl, J Bradley Layton
INTRODUCTION: Influenza infections contribute to excess healthcare utilization, morbidity, and mortality in individuals with glomerular disease (GD); however, influenza vaccination may not yield protective immune responses in this high-risk patient population. The objective of the present study was to describe influenza vaccine administration from 2010 to 2019 and explore the effectiveness of influenza vaccination in patients with GD. METHODS: We conducted an observational cohort study using healthcare claims for seasonal influenza vaccination (exposure) as well as influenza and influenza-like illness (outcomes) from commercially insured children and adults <65 years of age with primary GD in the Merative MarketScan Research Databases...
February 2024: KI Reports
https://read.qxmd.com/read/38344740/microchip-versus-piezoelectric-point-of-care-ultrasonography-for-pulmonary-and-vena-cava-evaluation-in-patients-with-acute-kidney-injury
#34
JOURNAL ARTICLE
Débora Miguel Soares, Renata de Souza Mendes, José Hermógenes Rocco Suassuna
INTRODUCTION: Point-of-care ultrasonography (POCUS) has emerged as an important tool for examining critically ill patients. POCUS devices have become progressively smaller and more accessible, transforming medical practice, and reducing costs. One technological breakthrough was the development of ultraportable scanners with microchip technology, which utilize a probe connected to a smartphone or tablet and incorporate a mobile application that employs artificial intelligence to assist in the interpretation of acquired images...
February 2024: KI Reports
https://read.qxmd.com/read/38344739/novel-treatment-paradigms-primary-iga-nephropathy
#35
REVIEW
Haresh Selvaskandan, Jonathan Barratt, Chee Kay Cheung
IgA nephropathy (IgAN) is the most common primary glomerulonephritis worldwide. Approximately 30% to 45% of patients progress to kidney failure (KF) within 20 to 25 years of diagnosis, and there has long been a lack of effective treatments. The therapeutic landscape in IgAN is rapidly evolving, driven in large part by the acceptance of the surrogate clinical trial end point of proteinuria reduction by regulatory authorities for the accelerated approval of new therapies. Two drugs, targeted release formulation (TRF)-budesonide (nefecon) and sparsentan, have recently been approved under this scheme...
February 2024: KI Reports
https://read.qxmd.com/read/38344738/all-about-abba-new%C3%A2-insights-into-antibrush-border-antibody-disease
#36
EDITORIAL
Vivette D D'Agati
No abstract text is available yet for this article.
February 2024: KI Reports
https://read.qxmd.com/read/38344737/risk-of-kidney-failure-and-mortality-in-patients-under-nephrology-care-in-nonhigh-income-settings
#37
JOURNAL ARTICLE
Murilo Guedes, Charlotte Tu, Brian Bieber, Viviane Calice Silva, Antonio Lopes, Ricardo Sesso, Natalia Alencar De Pinho, Roberto Pecoits-Filho
No abstract text is available yet for this article.
February 2024: KI Reports
https://read.qxmd.com/read/38344736/an-artificial-intelligence-generated-automated-algorithm-to-measure-total-kidney-volume-in-adpkd
#38
JOURNAL ARTICLE
Jonathan Taylor, Richard Thomas, Peter Metherall, Marieke van Gastel, Emilie Cornec-Le Gall, Anna Caroli, Monica Furlano, Nathalie Demoulin, Olivier Devuyst, Jean Winterbottom, Roser Torra, Norberto Perico, Yannick Le Meur, Sebastian Schoenherr, Lukas Forer, Ron T Gansevoort, Roslyn J Simms, Albert C M Ong
INTRODUCTION: Accurate tools to inform individual prognosis in patients with autosomal dominant polycystic kidney disease (ADPKD) are lacking. Here, we report an artificial intelligence (AI)-generated method for routinely measuring total kidney volume (TKV). METHODS: An ensemble U-net algorithm was created using the nnUNet approach. The training and internal cross-validation cohort consisted of all 1.5T magnetic resonance imaging (MRI) data acquired using 5 different MRI scanners (454 kidneys, 227 scans) in the CYSTic consortium, which was first manually segmented by a single human operator...
February 2024: KI Reports
https://read.qxmd.com/read/38344735/trajectory-of-gfr-decline-and-fluctuation-in-albuminuria-leading-to-end-stage-kidney-disease-in-patients-with-biopsy-confirmed-diabetic-kidney-disease
#39
JOURNAL ARTICLE
Masayuki Yamanouchi, Naoki Sawa, Tadashi Toyama, Miho Shimizu, Megumi Oshima, Yusuke Yoshimura, Hisashi Sugimoto, Shigekazu Kurihara, Yuki Oba, Daisuke Ikuma, Hiroki Mizuno, Akinari Sekine, Tatsuya Suwabe, Junichi Hoshino, Yoshifumi Ubara, Shigeko Hara, Kengo Furuichi, Takashi Wada
INTRODUCTION: Data on longitudinal trajectory of kidney function decline and fluctuation in albuminuria leading to end-stage kidney disease (ESKD) is sparse in patients with type 2 diabetes. METHODS: Using data from an observational study of patients with type 2 diabetes and biopsy-confirmed diabetic kidney disease (DKD), generalized additive mixed models (GAMMs) were performed to quantify patterns of longitudinal trajectory of estimated glomerular filtration rate (eGFR) decline to ESKD associated with repeated measures of urine albumin-to-creatinine ratio (ACR)...
February 2024: KI Reports
https://read.qxmd.com/read/38344734/kidney-dysfunction-and-pathology-in-the-setting-of-hemophagocytic-lymphohistiocytosis
#40
JOURNAL ARTICLE
Miroslav Sekulic, Ibrahim Batal, Satoru Kudose, Dominick Santoriello, M Barry Stokes, Belinda Jim, Hans-Peter Marti, Øystein Eikrem, Jai Radhakrishnan, Vivette D D'Agati, Glen S Markowitz
INTRODUCTION: Hemophagocytic lymphohistiocytosis (HLH) is a clinicopathologic syndrome produced by dysregulated activation of the immune system. Acute kidney injury (AKI) and proteinuria have been infrequently described in the setting of HLH, and investigations of underlying histopathologic changes in the kidney are limited. METHODS: To characterize kidney pathology in HLH, a retrospective review of 30 patients' clinical and laboratory data, and kidney tissue was performed (18 from autopsy, and 12 biopsied patients)...
February 2024: KI Reports
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