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SAGE Open Medical Case Reports

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https://www.readbyqxmd.com/read/30397477/gemcitabine-induced-skin-necrosis
#1
Maria Monica Haydock, Saroj Sigdel, Toni Pacioles
Since its emergence as a chemotherapy agent, gemcitabine has been associated with cutaneous adverse reactions. Rash is reported to be the most common cutaneous adverse effect. Other reported cutaneous reactions in the literature include bullous dermatosis, pseudocellulitis, subacute cutaneous lupus alopecia, and palmar-plantar erythrodysesthesia. Skin necrosis is a very rare adverse effect of this otherwise well-tolerated chemotherapeutic agent. In searching the literature, only one other case has been reported...
2018: SAGE Open Medical Case Reports
https://www.readbyqxmd.com/read/30397476/management-of-fractured-root-canal-treated-mandibular-molar-with-separated-endodontic-instrument-extending-in-periapical-region
#2
Shivkumar Mantri
The aim of this article is to present a case which demonstrates that debriding and disinfecting the infected, under-obturated canal of a tooth using standardized orthograde technique along with surgical retrieval of separated periapical instrument, heals the lesion of endodontic origin. Restoring the tooth with a definitive restoration involving core and crown reinstates the fractured tooth as a functional member of dental arch.
2018: SAGE Open Medical Case Reports
https://www.readbyqxmd.com/read/30397475/trichohepatoenteric-syndrome-a-rare-mutation-in-skiv2l-gene-in-the-first-balkan-reported-case
#3
Ioannis Xinias, Antigoni Mavroudi, Dimitrios Mouselimis, Anastasios Tsarouchas, Konstantina Vasilaki, Ioannis Roilides, Florence Lacaille, Olga Giouleme
Trichohepatoenteric syndrome or syndromic diarrhea is a rare and severe Mendelian autosomal recessive syndrome characterized by intractable diarrhea, facial and hair abnormalities, liver dysfunction, immunodeficiency and failure to thrive. It has been associated with mutations in TTC37 and SKIV2L genes, which encode proteins of the SKI complex that contributes to the cytosolic degradation of the messenger RNA by the cell's exosome. We report a case of a male infant who suffered from typical symptoms and signs of trichohepatoenteric syndrome without immunodeficiency...
2018: SAGE Open Medical Case Reports
https://www.readbyqxmd.com/read/30397474/angiosarcoma-complicating-lower-leg-elephantiasis-in-a-male-patient-an-unusual-clinical-complication-case-report-and-literature-review
#4
Eran Shavit, Afsaneh Alavi, James J Limacher, R Gary Sibbald
Chronic lymphedema is rarely complicated by an angiosarcoma. Angiosarcoma superimposed on chronic lymphedema (Stewart-Treves syndrome) is usually seen post breast cancer surgery accompanied by lymph node resection of the axilla. This is a case report of a 59-year-old male patient with elephantiasis that developed an angiosarcoma of the lower leg. He died a month after the diagnostic biopsy was obtained. This is a rare multifocal tumor in a male with an unusual lower leg location. We reviewed the literature and the need to differentiate this often deadly lesion from a Kaposi's sarcoma...
2018: SAGE Open Medical Case Reports
https://www.readbyqxmd.com/read/30386600/head-down-tilt-position-successfully-prevent-severe-brain-air-embolism
#5
Gaku Yamaguchi, Hiroyuki Miura, Eiji Nakajima, Norihiko Ikeda
Air embolisms are rare life-threatening complications that develop under various conditions, including surgery. During segmentectomy for thoracic surgery, air is blown into the selected bronchus for segment margin detection. This may result in the formation of an air embolus. Herein, we report a case of successful recovery from sudden intraoperative cardiac arrest due to an air embolism in a patient undergoing left superior division segmentectomy via open thoracotomy. Intraoperatively, the patient was positioned head-down...
2018: SAGE Open Medical Case Reports
https://www.readbyqxmd.com/read/30377530/successful-treatment-of-choreo-athetotic-movements-in-a-patient-with-an-eef1a2-gene-variant
#6
Eboni I Lance, Martin Kronenbuerger, Julie S Cohen, Orion Furmanski, Harvey S Singer, Ali Fatemi
Pathogenic variants in EEF1A2 , a gene encoding a eukaryotic translation elongation factor, have been previously reported in pediatric cases of epileptic encephalopathy and intellectual disability. We report a case of a 17-year-old male with a prior history of epilepsy, autism, intellectual disability, and the abrupt onset of choreo-athetotic movements. The patient was diagnosed with an EEF1A2 variant by whole exome sequencing. His movement disorder responded dramatically to treatment with tetrabenazine. To the best of our knowledge, this is the first report of successful treatment of a hyperkinetic movement disorder in the setting of EEF1A2 mutation...
2018: SAGE Open Medical Case Reports
https://www.readbyqxmd.com/read/30364512/membranous-nephropathy-followed-by-anti-glomerular-basement-disease-a-case-report-and-review-of-clinical-presentation-and-treatment
#7
Claudius Speer, Matthias Martin Gaida, Rüdiger Waldherr, Christian Nusshag, Florian Kälble, Martin Zeier
Membranous nephropathy is a common cause of nephrotic syndrome in adults and can be primary or secondary through autoimmune disease, medication, infection, or malignancy. Rapidly progressive glomerulonephritis with crescent formation is rare in patients with membranous nephropathy. Thus, in cases with rapid decline in renal function, after excluding complications such as malignant hypertension, acute hypersensitivity interstitial nephritis, and bilateral renal vein thrombosis, the simultaneous occurrence of a superimposed glomerulonephritis should be considered...
2018: SAGE Open Medical Case Reports
https://www.readbyqxmd.com/read/30364436/acute-stroke-thrombolysis-in-infective-endocarditis
#8
Abdulaziz Ashkanani, Zouhair Bitar, Osama Maadrani
Intravenous recombinant tissue plasminogen activator is not recommended for the treatment of acute ischemic stroke in patients with infective endocarditis due to the risk of hemorrhagic transformation of septic emboli and few reported cases in the literature. Here, we present the successful outcome of intravenous recombinant tissue plasminogen activator administration for a patient with acute ischemic stroke who was later found to have infective endocarditis. This case adds to the small number of cases reported in the literature...
2018: SAGE Open Medical Case Reports
https://www.readbyqxmd.com/read/30345057/use-of-quantiferon-tb-gold-to-determine-the-aetiology-of-idiopathic-erythema-induratum-a-case-report
#9
Alisa Brandon, Asfandyar Mufti, R Garry Sibbald
Although rare, erythema induratum is the most common entity presenting as lobular panniculitis with vasculitis. It is usually caused by a hypersensitivity reaction to Mycobacterium tuberculosis , although other aetiologies have been reported. We present a case of a 73-year-old male with multiple recurring tender erythematous nodules on the backs of both calves and shins. Prior to arrival in our clinic, the patient underwent a 9-month course of isoniazid with no improvement and subsequently received a diagnosis of idiopathic erythema induratum...
2018: SAGE Open Medical Case Reports
https://www.readbyqxmd.com/read/30345056/atypical-clinical-and-laboratory-features-of-fish-tank-granuloma-a-case-report
#10
Michael Sander, Judith L Isaac-Renton, Megan A Sander
We report a case of cutaneous Mycobacterium marinum infection with the unusual reported features of pruritus and paresthesia. In addition, we report a lack of in-vivo response to antibiotics based on in-vitro susceptibility testing.
2018: SAGE Open Medical Case Reports
https://www.readbyqxmd.com/read/30345055/linear-scar-sarcoidosis-on-thin-blepharoplasty-line-mimicking-a-hypertrophic-scar-a-case-report
#11
Seung Hwi Kwon, Kyung Muk Jeong, Yoo Sang Baek, Jiehyun Jeon
Sarcoidosis is a multisystem inflammatory disease of unknown aetiology. Skin involvement has been reported in 12%-27% of patients with systemic disease, and scar sarcoidosis is a form of sarcoidosis developing in previous cutaneous scar areas. Scars due to all kinds of trauma, including surgery, vaccines, cosmetic tattoos, and herpes zoster infection, have been reported to be associated with sarcoidosis. Upper eyelid blepharoplasty is a mainstay of aesthetic procedure and of surgical rejuvenation of the orbital region...
2018: SAGE Open Medical Case Reports
https://www.readbyqxmd.com/read/30345054/case-of-giant-vulvar-condyloma-acuminata-successfully-treated-with-imiquimod-3-75-cream-a-case-report
#12
Matthew Hum, Eunice Chow, Nan Schuurmans, Marlene Dytoc
Condyloma acuminata, also known as anogenital warts, represent a cutaneous infection caused by sexual transmission of the human papilloma virus. We present a case of overwhelming condyloma acuminata that was treated successfully without surgery using only topical imiquimod 3.75% cream. The patient, a 66-year-old female, was referred to Dermatology for large protruding verrucous plaques that covered the entire surface of her external vulva, perineum and perianal area. These lesions developed after being treated for genital warts with cantharidin...
2018: SAGE Open Medical Case Reports
https://www.readbyqxmd.com/read/30327719/not-just-another-sore-throat-extraluminal-migration-of-foreign-body-from-the-hypopharynx-a-case-report
#13
Al Omar M Salting
Meticulous history taking and careful examination should always be performed in all patients because a common symptom, such as sore throat, could be a presentation of an unusual problem. Sore throat from an ingested foreign body can perforate the mucosa and migrate extraluminally penetrating vital structures of the neck. Rare documentation of such cases involves sharp objects and, if untreated, may result in life-threatening complications. This article presents a case of a patient with a 3-week history of sore throat, and diagnostic work-up revealed a sharp metallic foreign body (needle pin) in the hypopharynx, which migrated extraluminally through the posterior pharyngeal wall...
2018: SAGE Open Medical Case Reports
https://www.readbyqxmd.com/read/30327718/acquired-widespread-lymphangiectasia-mimicking-immunobullous-disease-a-case-report
#14
Ross J Brothers, David R Crowe
A 76-year-old Caucasian woman presented with a 3-year history of a recurrent pruritic eruption on the hips, thighs, and under the breasts associated with intermittent lesions resembling vesicles and bullae that failed to respond to topical corticosteroids. She had a history of severe lichen sclerosis et atrophicus, leading to invasive squamous cell carcinoma of the vulva for which she underwent radical vulvectomy and bilateral inguino-femoral lymph node dissection. On physical examination, involving the inframammary breasts, abdomen, hips, and proximal thighs there were multiple erosions with hemorrhagic crust and multiple clustered translucent papules...
2018: SAGE Open Medical Case Reports
https://www.readbyqxmd.com/read/30302251/variable-response-of-post-mohs-surgery-telangiectasias-to-ktp-laser-a-case-report
#15
Catherine Villeneuve-Tang, Mélissa Nantel-Battista, Vincent Richer
A common but under-recognized complication of Mohs micrographic surgery is the development of surgical site telangiectasias after repair. Treatment with pulsed dye laser has shown good results in treating periscar telangiectasias, while treatment with KTP laser has never been studied for this complication. We report the findings in six patients with persistent telangiectasias post-Mohs micrographic surgery and their response to treatment with KTP laser. After one treatment with KTP laser, the severity of telangiectasias, scar erythema, and patient and physician-rated improvement were recorded...
2018: SAGE Open Medical Case Reports
https://www.readbyqxmd.com/read/30302250/photodistributed-sarcoidosis-a-case-report-and-approach-to-management
#16
Cristina Olteanu, Brandon Worley, Iris Teo, Jillian Macdonald
Sarcoidosis is an idiopathic disease, characterized by non-caseating granulomas in multiple organs/tissues. Cutaneous involvement occurs in approximately one-quarter of patients with a wide variety of presenting morphologies. This case report describes a case of photodistributed sarcoidosis, a rare cutaneous variant, with systemic involvement. A 42-year-old man presented with a history of a pruritic, rash with photoexacerbated annular plaques along with arthralgias and bone pain. Compared to previous reports of photodistributed sarcoidosis, our case presented with annular plaques rather than papules, and there was no prior exposure to ionizing radiation...
2018: SAGE Open Medical Case Reports
https://www.readbyqxmd.com/read/30214810/a-fatal-case-of-ortner-s-syndrome-and-dysphagia-aortica-secondary-to-rapidly-expanding-mycotic-thoracic-aortic-aneurysm-in-a-chronic-kidney-disease-patient
#17
Wynn Aung Kyaw, Chiao Yuen Lim, Muhammad Abdul Mabood Khalil, Kian Chai Lim, Vui Heng Chong, Jackson Tan
Ortner's syndrome or cardiovocal syndrome is a rare condition and refers to the association between cardiovascular conditions, usually cardiac enlargement from mitral stenosis, and recurrent laryngeal nerve palsy. We reported an interesting case of a patient with end-stage renal disease on regular dialysis who developed both Ortner's syndrome and dysphagia aortica as a result of an aortic arch aneurysm. The aneurysm underwent a rapid increase in size, likely as a result of Staphylococcus aureus infection (mycotic aneurysm) from an internal jugular dialysis catheter...
2018: SAGE Open Medical Case Reports
https://www.readbyqxmd.com/read/30214809/treating-electroconvulsive-therapy-induced-mania-with-more-electroconvulsive-therapy-evidence-for-electroconvulsive-therapy-as-the-ultra-mood-stabilizer
#18
Rejish K Thomas, Patrick J White, Serdar Dursun
Electroconvulsive therapy has been described as a mood stabilizer, as it is effective in all stages of bipolar disorder. Electroconvulsive therapy-induced mania is a known and potentially dangerous risk of treating bipolar depression with electroconvulsive therapy and there are no established guidelines for the management of electroconvulsive therapy-induced mania. We report a case of electroconvulsive therapy-induced mania where electroconvulsive therapy was continued as the sole, effective antimanic agent, which is the first described case in literature...
2018: SAGE Open Medical Case Reports
https://www.readbyqxmd.com/read/30214808/unusual-presentation-of-a-cutaneous-metastasis-in-the-face-arising-from-gastric-cancer-a-case-report
#19
Michael Constantin Kirchberger
A well-known example of gastrointestinal cancers metastasizing to the skin is Sister Mary Joseph's nodule, which usually presents as a cutaneous nodule on the umbilicus. In this case, a 91-year-old man was referred to our dermatology clinic for a rapidly growing 3 cm × 2 cm ulcerative nodule at his chin. Biopsy showed skin metastasis originating from a gastric adenocarcinoma. The subcutaneous and cutaneous manifestation of gastric cancer is very rare and associated with a poor prognosis and widespread metastatic disease as presented in this case...
2018: SAGE Open Medical Case Reports
https://www.readbyqxmd.com/read/30214807/a-case-report-of-bosutinib-induced-interstitial-granulomatous-drug-reaction-in-a-patient-with-chronic-myelogenous-leukemia-a-case-report
#20
Alexander B Aria, Leon Chen, Auris O Huen
Bosutinib is a BCR-ABL tyrosine kinase inhibitor approved for the treatment of Philadelphia chromosome-positive chronic myelogenous leukemia. We report a case of bosutinib-induced interstitial granulomatous drug reaction in a 50-year-old Caucasian female with chronic myelogenous leukemia. Histologic analysis of a punch biopsy showed diffuse interstitial granulomatous infiltrates consisting of histiocytes amid thickened collagen accompanied by eosinophils. Her lesions improved with clobetasol 0.05% cream. No cases describing BCR-ABL tyrosine kinase inhibitor-associated interstitial granulomatous drug reaction were found in a search of the literature...
2018: SAGE Open Medical Case Reports
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