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Acta Cardiologica Sinica

Ruey-Hsing Chou, Po-Hsun Huang, Wei-Chieh Huang
No abstract text is available yet for this article.
May 2018: Acta Cardiologica Sinica
Cheng-Wei Liu, Yen-Wen Wu
No abstract text is available yet for this article.
May 2018: Acta Cardiologica Sinica
Debika Chatterjee, Pradeep Narayan
No abstract text is available yet for this article.
May 2018: Acta Cardiologica Sinica
Taner Şeker, Caner Türkoğlu, Hazar Harbalıoğlu, Mustafa Gür
Background: Epicardial adipose tissue is an emerging cardio metabolic risk factor. Although an association between epicardial fat thickness (EFT) and left ventricle (LV) hypertrophy in hypertensive patients is known, the relationship between abnormal LV geometric patterns and EFT has yet to be investigated. The aim of the present study was to investigate the relationship between EFT and abnormal LV geometric patterns in hypertensive patients. Methods: Measurements were obtained from 343 patients with untreated essential hypertension (mean age 51...
May 2018: Acta Cardiologica Sinica
Fa-Po Chung, Chin-Yu Lin, Yenn-Jiang Lin, Shih-Ann Chen
No abstract text is available yet for this article.
May 2018: Acta Cardiologica Sinica
Wasawat Vutthikraivit, Pattara Rattanawong, Prapaipan Putthapiban, Weera Sukhumthammarat, Prin Vathesatogkit, Tachapong Ngarmukos, Ammarin Thakkinstian
Background: Brugada syndrome (BrS) is considered to be an inherited arrhythmic disease associated with fatal complications and premature sudden unexpected death. The prevalence of the Brugada electrocardiogram pattern (BrP) has been reported in several countries. Nonetheless, the specific worldwide prevalence of BrS has not been reported. Objective: We estimated the worldwide prevalence of BrS and Type-2/3 BrP in general adult populations using a systematic review and meta-analysis of the existing literature...
May 2018: Acta Cardiologica Sinica
Hakan Duman, Ilkay Bahçeci, Hikmet Hamur, Selami Demirelli, Aziz Ramazan Dilek, Turan Erdogan, Handan Duman, Ömer Şatıroğlu, Murtaza Emre Durakoğlugil
Background: Apelin, an endogenous peptide, has recently gained attention due to its positive inotropic effects in heart failure physiopathology. We investigated the relationship between serum apelin levels and the severity of calcific aortic stenosis (AS). Methods: A total of 68 consecutive patients diagnosed with calcific AS and a control group of 32 subjects were included in the study. The subjects were divided into three group as follows: the control group, the mild-moderate AS group and the severe AS group...
May 2018: Acta Cardiologica Sinica
Sedat Taş, Ümmü Taş, Ebru Özpelit, Efe Edem, Bahri Akdeniz
Background: Resting heart rate (HR) is a strong predictor of cardiovascular mortality and morbidity in patients with heart failure with reduced ejection fraction (HFrEF). However, the effects of HR-lowering therapy on diastolic function in HFrEF patients are not well described. In this study, we aimed to investigate the effect of lowering HR on diastolic function in HFrEF patients with sinus rhythm. Methods: Fifty patients with HFrEF with coexisting diastolic dysfunction and sinus rhythm with resting HR > 70 bpm were prospectively included in the study...
May 2018: Acta Cardiologica Sinica
Ting-Tse Lin, Wei-Shun Yang, Mu-Yang Hsieh, Chih-Chen Wu, Lian-Yu Lin
Background: Left ventricular hypertrophy (LVH) is prevalent in patients with end-stage renal disease (ESRD), and may be secondary to arterial stiffness and volume overload. It is unclear whether LVH is caused by autonomic nerve dysregulation (AND), a frequent condition in patients with ESRD that is characterized by sympathetic hyperactivity and vagal withdrawal. We hypothesized that AND estimated by heart rate variability (HRV) may be associated with LVH in patients with ESRD. Methods: We prospectively enrolled patients with ESRD undergoing hemodialysis...
May 2018: Acta Cardiologica Sinica
Bao-Feng Chen, Yun Deng, Xin Xu, Shao-Chun Ma, Liang-Qiu Tang, Jin-Feng Chen, Wei-Qian Sun, Su-Fang Liu, Jia-Rong Liang
Background: Lipoprotein-associated phospholipase A2 (Lp-PLA2 ) is a potential therapeutic target in acute coronary syndromes. Although recent evidence does not support the routine use of manual thrombus aspiration (TA) in patients with ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PPCI), the use of TA is associated with a significant improvement in myocardial reperfusion, especially in patients with high thrombus burden (HTB). We hypothesized that TA would reduce the serum Lp-PLA2 levels in STEMI patients undergoing PPCI with HTB...
May 2018: Acta Cardiologica Sinica
Kyung Seob Lim, Jun-Kyu Park, Myung Ho Jeong, In Ho Bae, Dae Sung Park, Jae Won Shim, Jung Ha Kim, Hyun Kuk Kim, Sung Soo Kim, Doo Sun Sim, Young Joon Hong, Ju Han Kim, Youngkeun Ahn
Background: Gallic acid (3,4,5-trihydroxybenzoic acid) is a natural polyphenol and strong natural antioxidant found abundantly in red wine and green tea. The aim of this study was to examine the anti-inflammatory effect of a novel gallic acid-eluting stent in a porcine coronary restenosis model. Methods: Fifteen pigs were randomized into three groups; in which a total of 30 coronary arteries (10 in each group) were implanted with gallic acid-eluting stents (GESs, n = 10), gallic acid and sirolimus-eluting stents (GSESs, n = 10), or sirolimus-eluting stents (SESs, n = 10)...
May 2018: Acta Cardiologica Sinica
Kuan-Chun Chen, Wei-Hsian Yin, Chih-Cheng Wu, Shih-Hung Chan, Yen-Wen Wu, Kuo Yang Wang, Kuan-Cheng Chang, Juey-Jen Hwang, Wen-Chol Voon, I-Chang Hsieh, Jun-Ted Chong, Wei-Shiang Lin, Chih-Neng Hsu, Kwo-Chang Ueng, Chih-Ping Hsia, Ju-Chi Liu, Jong-Shiuan Yeh, Guang-Yuan Mar, Jhih-Yuan Shih, Jen-Yuan Kuo, Hsuan-Ming Tsao, Wei-Kung Tseng, Cheng-Hsu Yang, Chao-Chien Chang, Chern-En Chiang, Meng-Heng Lei, Jeng-Feng Lin, Kou-Gi Shyu
Background: Patients with acute coronary syndrome (ACS) and diabetes mellitus (DM) receive less aggressive treatment and have worse outcomes in Taiwan. We sought to explore whether the current practices of prescribing guideline-directed medical therapy (GDMT) for ACS and clinical outcomes have improved over time. Methods: A total of 1534 consecutive diabetic patients with ACS were enrolled between 2013 and 2015 from 27 hospitals in the nationwide registry initiated by the Taiwan Society of Cardiology (the TSOC ACS-DM Registry)...
May 2018: Acta Cardiologica Sinica
Yi-Heng Li, Chih-Yuan Fang, I-Chang Hsieh, Wei-Chun Huang, Tsung-Hsien Lin, Shih-Hsien Sung, Chiung-Zuan Chiu, Chiung-Jen Wu, Kou-Gi Shyu, Po-Yuan Chang, Ching-Chang Fang, Tse-Min Lu, Ching-Pei Chen, Wei-Chen Tai, Chau-Chyun Sheu, Kai-Che Wei, Yi-Hsiu Huang, Hsing-Mei Wu, Juey-Jen Hwang Hwang
Antiplatelet therapy is a key component in the treatment of acute coronary syndrome (ACS). The management of ACS has evolved considerably over recent years with the development of new and more potent antiplatelet agents. Clinical trials on ACS have demonstrated that potent antiplatelet agents can more effectively reduce cardiovascular events. However, there is a tipping point between safety and efficacy, beyond which the risk of bleeding and other adverse effects can outweigh the benefits of antiplatelet therapy...
May 2018: Acta Cardiologica Sinica
Hsiu-Hao Lee, Yueh-Chung Chen, Jien-Jiun Chen, Shih-Hsiang Lo, Yue-Liang Guo, Hsiao-Yun Hu
No abstract text is available yet for this article.
March 2018: Acta Cardiologica Sinica
Tomoyuki Kawada
No abstract text is available yet for this article.
March 2018: Acta Cardiologica Sinica
Ming-Fu Chen, Cheng-Hsuan Ho, Tsung-Neng Tsai, Pai-Shan Chen, Sy-Jou Chen
No abstract text is available yet for this article.
March 2018: Acta Cardiologica Sinica
Yiping Wang, Yingqiong Huang, Min Zhang, Xiaoqin Zhang, Xuemei Tang, Yan Kang
Background: Both miR-30a and miR-30e are significantly downregulated in cardiomyocytes (CMs) 2 days (d) post myocardial infarction (MI). This study aimed to identify their possible regulative network in CMs 2d post-MI. Methods: The dysregulated mRNAs in left ventricle tissues 2d post-MI in mice model were retrieved from one previous publication. The verified target genes of miR-30a/e and the predicted targets (upregulated 2d post-MI) were subjected to analysis of the involvement in biological processes according to their enrichment in gene ontology (GO) terms...
March 2018: Acta Cardiologica Sinica
Li-Tan Yang, Yao-Mao Chang, Tsung-Han Hsieh, Wen-Hsuan Hou, Chung-Yi Li
Background: We conducted a time-series analysis of daily ambient temperature and all-cause, cardiovascular, and respiratory disease mortality in Taiwan, which is generally neither extremely hot nor cold. Methods: Data on all-cause daily mortality rates (excluding accidents, suicide, and homicide), and mortality rates due to respiratory and cardiovascular diseases between 2008 and 2010 were obtained from the Taiwan Death Registry. The daily temperature for that period was averaged from 33 monitoring stations nationwide...
March 2018: Acta Cardiologica Sinica
Mustafa Zungur, Ilker Gul, Senol Kobak
Background: We aimed to evaluate the right ventricular (RV) systolic function in patients with ankylosing spondylitis (AS) compared to healthy subjects by using standard echocardiography and speckle-tracking echocardiography (STE) methods. Methods: This was a case-control study in which 64 patients (mean age, 55.7 ± 9.2 years; male/female, 53/11), who had AS for at least five years (mean disease duration, 7.1 ± 2.6 years) and 70 age-matched healthy subjects (mean age, 54...
March 2018: Acta Cardiologica Sinica
Jing-Wei Kang, Wei-Hsiang Yang, Jia-En Chi, Wei-Ta Chen
Background: Ventricular premature complexes (VPCs) with a burden higher than 10% to 20% of total daily heart beats can cause VPC-induced cardiomyopathy. The systolic blood pressure response (SBPR) is the difference between the SBP during maximal exercise and rest. A low SBPR was recently identified to be a marker of cardiomyopathy. The aim of this manuscript was to clarify the association between VPC burden and SBPR. Methods: From January to December 2015, all patients with a VPC burden larger than 240 beats/day on Holter recordings and treadmill exercise tests were enrolled...
March 2018: Acta Cardiologica Sinica
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