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Asia Oceania Journal of Nuclear Medicine & Biology

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https://www.readbyqxmd.com/read/29333471/sectional-anatomy-quiz-ii
#1
Rashid Hashmi
This mage-based series comprises of a quiz pertaining to the identification of salient and important anatomical structures and landmarks expected to be seen at a given level on the computed tomography (CT). The representative image is followed by a series of images showing the examples of different commonly encountered pathological entities that can be seen at this level in a routine clinical practice. Readers are encouraged to identify the highlighted anatomical structures and landmarks in all the images and appreciate the alterations in the appearance of the normal structures resulting from the presence of a pathology...
2018: Asia Oceania Journal of Nuclear Medicine & Biology
https://www.readbyqxmd.com/read/29333470/history-and-perspectives-of-nuclear-medicine-in-myanmar
#2
Win Mar
Nuclear Medicine was established in Myanmar in 1963 by Dr Soe Myint and International Atomic Energy expert Dr R. Hochel at Yangon General Hospital. Nuclear medicine diagnostic and therapeutic services started with Probe Scintillation Detector Systems and rectilinear scanner. In the early stage, many Nuclear Medicine specialists from the International Atomic Energy Agency (IAEA) spent some time in Myanmar and made significant contributions to the development of Nuclear Medicine in our country. The department participated in various IAEA technical cooperation projects and regional cooperation projects...
2018: Asia Oceania Journal of Nuclear Medicine & Biology
https://www.readbyqxmd.com/read/29333469/utility-of-f-18-fdg-pet-ct-for-detection-of-bone-marrow-metastases-in-prostate-cancer-patients-treated-with-radium-223
#3
Kaoru Maruyama, Keita Utsunomia, Takahiro Nakamoto, Shigenari Kawakita, Takashi Murota, Noboru Tanigawa
A 76-year-old man with symptomatic bone metastases from castration-resistant prostate cancer underwent Radium-223-dichloride (Ra-223) therapy. Before Ra-223 therapy, he had normal peripheral blood cell counts. Ra-223 therapy relieved his shoulder and low back pain. The elevation of the serum prostate-specific antigen (PSA), doubling every month during Ra-223 therapy, suggested a PSA flare or relapse. Some lesions showed decrease and some lesions showed increase on Tc-99m hydroxymethylene diphosphonate bone scintigraphy at two weeks after the third injection of Ra-223 therapy...
2018: Asia Oceania Journal of Nuclear Medicine & Biology
https://www.readbyqxmd.com/read/29333468/extraosseous-accumulation-of-technetium-99m-methyl-diphosphonate-99m-tc-mdp-in-a-child-with-all-a-case-report
#4
Farnaz Banezhad, Narjess Ayati, Farrokh Seilanian Toosi, Samine Boloursaz, S Rasoul Zakavi
Extraosseous accumulation of technetium-99m-methyl diphosphonate (99m Tc-MDP) on bone scan is not common. This phenomenon is often attributed to abnormality of calcium metabolism and has been reported in a variety of conditions including metabolic diseases and malignancies. A five years old boy is presented here, who was admitted to the pediatric emergency suffering from fatigue, respiratory symptoms, weight loss, intermittent fevers, anorexia, nausea and vomiting, edema of legs and abdominal distension for one month...
2018: Asia Oceania Journal of Nuclear Medicine & Biology
https://www.readbyqxmd.com/read/29333467/a-simple-non-invasive-i-123-imp-autoradiography-method-developed-by-modifying-the-simple-non-invasive-i-123-imp-microsphere-method
#5
Asato Ofuji, Rieko Nagaoka, Kosuke Yamashita, Akihiro Takaki, Shigeki Ito
Objectives: We developed a simple non-invasive I-123-N-isopropyl-p-iodoamphetamine (123 I-IMP) quantification method by analyzing chest RI-angiography and single photon emission computed tomography (SPECT) images based on the microsphere model (SIMS method). Theoretically, the SIMS method could be changed to the simple non-invasive ARG (SIARG) method by modifying the integrated washout ratio (WR) to one-point WR. If the regional cerebral blood flow (rCBF) values derived from the SIARG and ARG methods correlate well, the facilities employing the ARG method can easily switch to the SIARG method...
2018: Asia Oceania Journal of Nuclear Medicine & Biology
https://www.readbyqxmd.com/read/29333466/evaluation-of-the-possible-utilization-of-68-ga-dotatoc-in-diagnosis-of-adenocarcinoma-breast-cancer
#6
Samaneh Zolghadri, Mojdeh Naderi, Hassan Yousefnia, Behrouz Alirezapour, Davood Beiki
Objectives: Studies have indicated advantageous properties of [DOTA-DPhe1 , Tyr3 ] octreotide (DOTATOC) in tumor models and labeling with gallium. Breast cancer is the second leading cause of cancer mortality in women, and most of these cancers are often an adenocarcinoma. Due to the importance of target to non-target ratios in the efficacy of diagnosis, the pharmacokinetic of 68 Ga-DOTATOC in an adenocarcinoma breast cancer animal model was studied in this research, and the optimized time for imaging was determined...
2018: Asia Oceania Journal of Nuclear Medicine & Biology
https://www.readbyqxmd.com/read/29333465/in-vivo-exposure-effects-of-99m-tc-methoxyisobutylisonitrile-on-the-fdxr-and-xpa-genes-expression-in-human-peripheral-blood-lymphocytes
#7
Mohammad Taghi Bahreyni-Toossi, Habibeh Vosoughi, Hosein Azimian, Abdul Rahim Rezaei, Mehdi Momennezhad
Objectives: In recent years, the application of radiopharmaceuticals in nuclear medicine has increased substantially. Following the diagnostic procedures performed in nuclear medicine departments, such as myocardial perfusion imaging, patients generally receive considerable doses of radiation. Normally, radiation-induced DNA damages are expected following exposure to a low-dose ionizing radiation. In order to detect molecular changes, high-sensitivity techniques must be utilized. The aim of this study was to assess the effect of a low-dose (below 10 mSv) gamma ray on gene expression using quantitative real-time polymerase chain reaction (qRT-PCR)...
2018: Asia Oceania Journal of Nuclear Medicine & Biology
https://www.readbyqxmd.com/read/29333464/comparison-of-tof-pet-and-bremsstrahlung-spect-images-of-yttrium-90-a-monte-carlo-simulation-study
#8
Akihiko Takahashi, Kazuhiko Himuro, Shingo Baba, Yasuo Yamashita, Masayuki Sasaki
Objectives: Yttrium-90 (90 Y) is a beta particle nuclide used in targeted radionuclide therapy which is available to both single-photon emission computed tomography (SPECT) and time-of-flight (TOF) positron emission tomography (PET) imaging. The purpose of this study was to assess the image quality of PET and Bremsstrahlung SPECT by simulating PET and SPECT images of 90 Y using Monte Carlo simulation codes under the same conditions and to compare them. Methods: In-house Monte Carlo codes, MCEP-PET and MCEP-SPECT, were employed to simulate images...
2018: Asia Oceania Journal of Nuclear Medicine & Biology
https://www.readbyqxmd.com/read/29333463/characteristics-of-smoothing-filters-to-achieve-the-guideline-recommended-positron-emission-tomography-image-without-harmonization
#9
Yuji Tsutsui, Shinichi Awamoto, Kazuhiko Himuro, Yoshiyuki Umezu, Shingo Baba, Masayuki Sasaki
Objectives: The aim of this study is to examine the effect of different smoothing filters on the image quality and SUVmax to achieve the guideline recommended positron emission tomography (PET) image without harmonization. Methods: We used a Biograph mCT PET scanner. A National Electrical Manufacturers Association (NEMA) the International Electrotechnical Commission (IEC) body phantom was filled with 18 F solution with a background activity of 2.65 kBq/mL and a sphere-to-background ratio of 4...
2018: Asia Oceania Journal of Nuclear Medicine & Biology
https://www.readbyqxmd.com/read/29333462/assessment-of-ultrasound-radio-guided-occult-lesion-localization-in-non-palpable-breast-lesions
#10
Seyed Ali Alamdaran, Donia Farokh, Ayda Sharifi Haddad, Navid Daghighi, Elaheh Modoodi, Ramin Sadeghi, Mohammad Naser Forghani, Asieh Sadat Fattahi
Objectives: Controversy exists about the localization of non-palpable breast lesions. In many countries, the gold standard for the diagnosis of these lesions is needle localization due to its accuracy. This study sought to compare the ultrasound- and radio-guided occult lesion localization (ROLL) as a simple method with the conventional procedures in terms of their diagnostic power. Methods: This study was conducted on 94 patients with non-palpable breast lesions detected by ultrasonography and localized by the combination of ultrasonography and using radiopharmaceuticals...
2018: Asia Oceania Journal of Nuclear Medicine & Biology
https://www.readbyqxmd.com/read/29333461/extracorporeal-shock-wave-therapy-for-coronary-artery-disease-relationship-of-symptom-amelioration-and-ischemia-improvement
#11
Youko Takakuwa, Masayoshi Sarai, Hideki Kawai, Akira Yamada, Kenji Shiino, Kayoko Takada, Yasuomi Nagahara, Meiko Miyagi, Sadako Motoyama, Hiroshi Toyama, Yukio Ozaki
Objectives: The current management of coronary artery disease (CAD) relies on three major therapeutic options, namely medication, percutaneous coronary intervention (PCI), and coronary artery bypass grafting (CABG). However, severe CAD that is not indicated for PCI or CABG still bears a poor prognosis due to the lack of effective treatments. In 2006, extracorporeal cardiac shock wave (SW) therapy reported on human for the first time. This treatment resulted in better myocardial perfusion as evaluated by dipyridamole stress thallium scintigraphy, angina symptoms, and exercise tolerance...
2018: Asia Oceania Journal of Nuclear Medicine & Biology
https://www.readbyqxmd.com/read/28840142/-18-f-fdg-pet-ct-in-pleural-epithelioid-hemangioendothelioma
#12
Domenico Albano, Giovanni Bosio, Andrea Tironi, Francesco Bertagna
Pleural epithelioid hemangioendothelioma (EHE) is a rare malignancy of vascular-endothelial origin with non-specific symptoms and an unpredictable outcome. Diagnosis of this condition by imaging modalities is challenging, and no standard therapeutic approaches have been established in this regard. In this paper, we described the case of a patient with a low-grade fever, coughing and chest pain who underwent (18)F-FDG PET/CT after a positive thorax CT showing multiple bilateral calcified pulmonary nodules and extensive right-sided pleural effusion...
2017: Asia Oceania Journal of Nuclear Medicine & Biology
https://www.readbyqxmd.com/read/28840141/changing-therapeutic-paradigms-predicting-mcrc-lesion-response-to-selective-internal-radionuclide-therapy-sirt-based-on-critical-absorbed-dose-thresholds-a-case-study
#13
Kathy P Willowson, Elizabeth J Bernard, Richard Maher, Stephen J Clarke, Dale L Bailey
A 65 year old male with metastatic colorectal cancer (mCRC) in the liver was referred for selective internal radionuclide therapy (SIRT) following a history of extensive systemic chemotherapy. (90)Y PET imaging was performed immediately after treatment and used to confirm lesion targeting and measure individual lesion absorbed doses. Lesion dosimetry was highly predictive of eventual response in the follow-up FDG PET performed 8 weeks after therapy. The derived radiation dose map was used to plan a second SIRT procedure aiming to protect healthy liver by keeping absorbed dose below the critical dose threshold, whilst targeting the remaining lesions that had received sub-critical dosing...
2017: Asia Oceania Journal of Nuclear Medicine & Biology
https://www.readbyqxmd.com/read/28840140/salivary-gland-scintigraphy-in-patients-with-sjogren-s-syndrome-a-local-experience-with-dual-tracer
#14
Wing Hang Luk, Jessie Tse Hang Yeung, Eliza Po Yan Fung, Chiu Ming Lok, Yuet Ming Ng
OBJECTIVES: To review the findings of the patients with Sjögren's syndrome (SS) having technetium99-m-pertechnetate ((99m)Tc-pertechnetate) and gallium67- citrate (Ga-67) salivary gland scintigraphy in the past eight years. METHODS: The patients with SS, who were referred to our department for salivary gland scintigraphy during January -2008December 2015 were studied using both (99m)Tc-pertechnetate and Ga-67 citrate scintigraphy. RESULTS: Eighteen patients were included in the study, 17 of whom had positive findings on (99m)Tc-pertechnetate salivary gland scintigraphy...
2017: Asia Oceania Journal of Nuclear Medicine & Biology
https://www.readbyqxmd.com/read/28840139/influence-of-the-different-primary-cancers-and-different-types-of-bone-metastasis-on-the-lesion-based-artificial-neural-network-value-calculated-by-a-computer-aided-diagnostic-system-bonenavi-on-bone-scintigraphy-images
#15
Takuro Isoda, Shingo BaBa, Yasuhiro Maruoka, Yoshiyuki Kitamura, Keiichiro Tahara, Masayuki Sasaki, Masamitsu Hatakenaka, Hiroshi Honda
OBJECTIVES: BONENAVI, a computer-aided diagnostic system, is used in bone scintigraphy. This system provides the artificial neural network (ANN) and bone scan index (BSI) values. ANN is associated with the possibility of bone metastasis, while BSI is related to the amount of bone metastasis. The degree of uptake on bone scintigraphy can be affected by the type of bone metastasis. Therefore, the ANN value provided by BONENAVI may be influenced by the characteristics of bone metastasis...
2017: Asia Oceania Journal of Nuclear Medicine & Biology
https://www.readbyqxmd.com/read/28840138/evaluation-of-the-efficacy-of-standardized-uptake-value-suv-shape-scheme-for-thyroid-volume-determination-in-graves-disease-a-comparison-with-ultrasonography
#16
Yangchun Chen, Si Pei Xie, Fang He, Jianwei Chen
OBJECTIVES: In this study, we aimed to evaluate the efficacy of thyroid volume measurement using (99m)Tc pertechnetate single-photon emission computed tomography (SPECT) images, acquired by the standardized uptake value (SUV)-shape scheme designed by our expert team. METHODS: A total of 18 consecutive patients with Graves' disease (GD) were subjected to both ultrasonographic and (99m)Tc pertechnetate SPECT examinations of thyroid within a five-day interval. The volume of thyroid lobes and isthmus was measured by ultrasonography (US) according to the ellipsoid volume equation...
2017: Asia Oceania Journal of Nuclear Medicine & Biology
https://www.readbyqxmd.com/read/28840137/uptake-index-of-123-i-metaiodobenzylguanidine-myocardial-scintigraphy-for-diagnosing-lewy-body-disease
#17
Yoshito Kamiya, Satoru Ota, Shintaro Okumiya, Kosuke Yamashita, Akihiro Takaki, Shigeki Ito
OBJECTIVES: Iodine-123 metaiodobenzylguanidine ((123)I-MIBG) myocardial scintigraphy has been used to evaluate cardiac sympathetic denervation in Lewy body disease (LBD), including Parkinson's disease (PD) and dementia with Lewy bodies (DLB). The heart-to-mediastinum ratio (H/M) in PD and DLB is significantly lower than that in Parkinson's plus syndromes and Alzheimer's disease. Although this ratio is useful for distinguishing LBD from non-LBD, it fluctuates depending on the system performance of the gamma cameras...
2017: Asia Oceania Journal of Nuclear Medicine & Biology
https://www.readbyqxmd.com/read/28840136/the-efficiency-of-respiratory-gated-18-f-fdg-pet-ct-in-lung-adenocarcinoma-amplitude-gating-versus-phase-gating-methods
#18
Yoshiyuki Kitamura, Shingo Baba, Takuro Isoda, Yasuhiro Maruoka, Satoshi Kawanami, Kazuhiko Himuro, Masayuki Sasaki, Hiroshi Honda
OBJECTIVES: In positron emission tomography (PET) studies, thoracic movement under free-breathing conditions is a cause of image degradation. Respiratory gating (RG) is commonly used to solve this problem. Two different methods, i.e., phase-gating (PG) and amplitude-gating (AG) PET, are available for respiratory gating. It is important to know the strengths and weaknesses of both methods when selecting an RG method for a given patient. We conducted this study to clarify whether AG or PG is preferable for measuring fluorodeoxyglucose (FDG) accumulation in lung adenocarcinoma and to investigate patient conditions which are most suitable for AG and PG methods...
2017: Asia Oceania Journal of Nuclear Medicine & Biology
https://www.readbyqxmd.com/read/28840135/assessment-of-mediastinal-tumors-using-suvmax-and-volumetric-parameters-on-fdg-pet-ct
#19
Takahiro Morita, Mitsuaki Tatsumi, Mana Ishibashi, Kayako Isohashi, Hiroki Kato, Osamu Honda, Eku Shimosegawa, Noriyuki Tomiyama, Jun Hatazawa
OBJECTIVES: This study aimed to evaluate the role of pretreatment SUVmax and volumetric FDG positron emission tomography (PET) parameters in the differentiation between benign and malignant mediastinal tumors. In addition, we investigated whether pretreatment SUVmax and volumetric FDG-PET parameters could distinguish thymomas from thymic carcinomas, and low-risk from high-risk thymomas. METHODS: This study was conducted on 52 patients with mediastinal tumors undergoing FDG-PET/CT...
2017: Asia Oceania Journal of Nuclear Medicine & Biology
https://www.readbyqxmd.com/read/28840134/diagnostic-performance-and-safety-of-positron-emission-tomography-using-18-f-fluciclovine-in-patients-with-clinically-suspected-high-or-low-grade-gliomas-a-multicenter-phase-iib-trial
#20
Toshihiko Wakabayashi, Toshihiko Iuchi, Naohiro Tsuyuguchi, Ryo Nishikawa, Yoshiki Arakawa, Takashi Sasayama, Keisuke Miyake, Tadashi Nariai, Yoshitaka Narita, Naoya Hashimoto, Osamu Okuda, Hiroshi Matsuda, Kazuo Kubota, Kimiteru Ito, Yoichi Nakazato, Kan Kubomura
OBJECTIVES: The study objective was to assess the diagnostic performance of positron emission tomography (PET) for gliomas using the novel tracer 18 F-fluciclovine (anti-[18 F]FACBC) and to evaluate the safety of this tracer in patients with clinically suspected gliomas. METHODS: Anti-[18 F]FACBC was administered to 40 patients with clinically suspected high- or low-grade gliomas, followed by PET imaging. T1-weighted, contrast-enhanced T1-weighted, and fluid-attenuated inversion recovery (or T2-weighted) magnetic resonance imaging (MRI) scans were obtained to plan for the tissue collection...
2017: Asia Oceania Journal of Nuclear Medicine & Biology
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