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JDR Clinical and Translational Research

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https://www.readbyqxmd.com/read/29568804/screening-for-diabetes-risk-using-integrated-dental-and-medical-electronic-health-record-data
#1
A Acharya, B Cheng, R Koralkar, B Olson, I B Lamster, C Kunzel, E Lalla
Undiagnosed diabetes and prediabetes present a serious public health challenge. We previously reported that data available in the dental setting can serve as a tool for early dysglycemia identification in a primarily Hispanic, urban population. In the present study, we sought to determine how the identification approach can be recalibrated to detect diabetes or prediabetes in a White, rural cohort and whether an integrated dental-medical electronic health record (iEHR) offers further value to the process. We analyzed iEHR data from the Marshfield Clinic, a health system providing care in rural Wisconsin, for dental patients who were ≥21 y of age, reported that they had never been told they had diabetes, had an initial periodontal examination of at least 2 quadrants, and had a glycemic assessment within 3 mo of that examination...
April 2018: JDR Clinical and Translational Research
https://www.readbyqxmd.com/read/29568803/school-based-caries-prevention-tooth-decay-and-the-community-environment
#2
R R Ruff, R Niederman
The school and community context can contribute to inequity in child oral health. Whether the school and community affect the effectiveness of school-based caries prevention is unknown. The association between the school and community environment and dental caries, as well as their moderating effects with school-based caries prevention, was assessed using multilevel mixed-effects regression. Data were derived from a 6-y prospective cohort study of children participating in a school-based caries prevention program...
April 2018: JDR Clinical and Translational Research
https://www.readbyqxmd.com/read/29568802/evidence-of-early-emergence-of-the-primary-dentition-in-a-northern-plains-american-indian-population
#3
D V Dawson, D R Blanchette, J M Douglass, N Tinanoff, K W O Kramer, J J Warren, K R Phipps, D E Starr, T A Marshall, T R Mabry, K Pagan-Rivera, J A Banas, D R Drake
The purposes of this study were to describe primary tooth emergence in an American Indian (AI) population during the first 36 mo of life to compare 1) patterns of emergence between male and female children and 2) tooth emergence between these AI children and other U.S. ethnic groups. Data were derived from a birth cohort of 239 AI children from a Northern Plains tribe participating in a longitudinal study of early childhood caries, with examination data at target ages of 8, 12, 16, 22, 28, and 36 mo of age (±1 mo)...
April 2018: JDR Clinical and Translational Research
https://www.readbyqxmd.com/read/29556552/the-value-of-orthodontics-do-parents-willingness-to-pay-values-reflect-the-iotn
#4
Christopher Vernazza, Lauren Anderson, Andrew Ian Hunter, Helen Christine Leck, Stephen Daniel O'Connor, Gillian Rose Smith, Richard Joseph Stokes, Sarah Rolland
Introduction: Given the limited evidence about the benefits of orthodontic treatment, many health care systems have rationed access to orthodontic care with the Index of Orthodontic Treatment Need (IOTN) being one tool used to attempt to allocate resources based on need. However, it is not clear whether patient and public valuations of different levels of need (as described by the IOTN) reflect the resource allocation decisions. The aim of this project was therefore to determine the values parents placed on correction of malocclusions at different IOTN levels using the willingness to pay (WTP) technique...
April 1, 2018: JDR Clinical and Translational Research
https://www.readbyqxmd.com/read/29662960/impact-of-oral-hygiene-discontinuation-on-supragingival-and-salivary-microbiomes
#5
D Belstrøm, M L Sembler-Møller, M A Grande, N Kirkby, S L Cotton, B J Paster, S Twetman, P Holmstrup
The purpose of the present study was to characterize and compare supragingival and salivary microbiotas during a 10-d period of oral hygiene discontinuation. We tested the hypothesis that the composition of the salivary microbiota will reflect local microbial changes associated with accumulated biofilm formation and maturation. Pooled supragingival plaque ( n = 145) and stimulated saliva ( n = 145) samples were collected and plaque and gingival indices were recorded from 29 orally healthy individuals at baseline, during oral hygiene discontinuation (days 4, 7, and 10), and 14 d after resumption of oral hygiene...
January 2018: JDR Clinical and Translational Research
https://www.readbyqxmd.com/read/29276779/the-effects-of-medical-well-baby-visits-in-promoting-earlier-first-dental-visits-for-children
#6
S Park, E T Momany, M P Jones, R A Kuthy, N M Askelson, G L Wehby, P C Damiano, D L Chi
The objective of the study was to assess the effects of medical well baby visits in promoting earlier first dental visits. We analyzed Iowa Medicaid claims data (2000-2013). The sample included 4 cohorts of children born in 2000, 2003, 2007, or 2010 and enrolled in Medicaid from birth ( N = 38,211). Children were followed for 3 y. The independent variables were cohort year and medical well baby visit frequency during 3 time periods (birth to age 10 mo, ages 11-19 mo, ages 20-36 mo). We used survival analyses to estimate first dental visit rates...
January 2018: JDR Clinical and Translational Research
https://www.readbyqxmd.com/read/29276778/maternal-factors-associated-with-early-childhood-caries-in-urban-latino-children
#7
T Tiwari, A R Wilson, M Mulvahill, N Rai, J Albino
The objective of this investigation was to describe maternal psychosocial, behavioral, and acculturation factors associated with early childhood caries in a sample of urban Latino mother-child dyads. A cross-sectional survey was conducted with 100 mothers whose children (under the age of 6 y) were patients at the Dental Center at Children's Hospital Colorado in Aurora, Colorado. All children participating in the study received an oral examination to measure decayed, missing, filled, surfaces (dmfs). Participating mothers were given the option to sign the consent form and complete the survey in English or Spanish, according to their preferred language...
January 2018: JDR Clinical and Translational Research
https://www.readbyqxmd.com/read/29276777/patient-centered-dentinal-hypersensitivity-treatment-outcomes-results-from-the-national-dental-pbrn
#8
M W Heft, M S Litaker, D T Kopycka-Kedzierawski, C Meyerowitz, S Chonowski, R L Yardic, V V Gordan, R Mungia, G H Gilbert
Dentinal hypersensitivity (DH) can have a significant impact on oral health and functioning, and it is a clinical symptom commonly managed by dentists during routine clinical practice. DH symptoms are typically elicited by otherwise innocuous, nonpainful stimuli applied to exposed dentin (e.g., tactile stimuli, warming or cooling temperatures or air puffs). Treatment approaches have sought to directly target the dentinal pulp tissues or close dentinal tubules via dental office care and treatment services (fluoride varnishes, glutaraldehydes, bonding agents, sealants, oxalates, or lasers) or home care services (toothpastes or dentifrices containing fluoride or potassium nitrate compounds)...
January 2018: JDR Clinical and Translational Research
https://www.readbyqxmd.com/read/29276776/periodontitis-in-ch%C3%A3-diak-higashi-syndrome-an-altered-immunoinflammatory-response
#9
V Thumbigere Math, P Rebouças, P A Giovani, R M Puppin-Rontani, R Casarin, L Martins, L Wang, K Krzewski, W J Introne, M J Somerman, F H Nociti, K R Kantovitz
Chédiak-Higashi syndrome (CHS), a rare autosomal recessive disorder caused by mutations in the lysosomal trafficking regulator gene (LYST), is associated with aggressive periodontitis. It is suggested that LYST mutations affect the toll-like receptor (TLR)-mediated immunoinflammatory response, leading to frequent infections. This study sought to determine the periodontal status of patients with classic (severe) and atypical (milder) forms of CHS and the immunoregulatory functions of gingival fibroblasts in CHS patients...
January 2018: JDR Clinical and Translational Research
https://www.readbyqxmd.com/read/29276775/task-force-on-design-and-analysis-in-oral-health-research-host-microbiome-interactions-in-dysbiosis
#10
T E Van Dyke, P I Diaz, N Moutsopoulos, A V Alekseyenko, E Ioannidou
Knowledge Transfer Statement: This article discusses the proceedings of the conference organized by the Task Force on Design and Analysis in Oral Health Research on the new advances in host-microbiome interactions, analytical methods, and their implication in inflammatory periodontal disease management.
January 2018: JDR Clinical and Translational Research
https://www.readbyqxmd.com/read/28944293/preventing-caries-in-american-indian-children-lost-battle-or-new-hope
#11
J Albino, T S Batliner, T Tiwari
Knowledge Transfer Statement: Preventing early childhood caries in American Indian children has proved to be an unexpectedly challenging goal. Biological and behavioral variables, as well as parental psychosocial characteristics and experiences, suggest new routes for understanding and mitigating the progress of disease. We provide our reflections after a decade of studying these issues in collaboration with tribal communities.
October 2017: JDR Clinical and Translational Research
https://www.readbyqxmd.com/read/28944292/early-head-start-pediatric-dental-use-and-oral-health-related-quality-of-life
#12
J M Burgette, J S Preisser, M Weinberger, R S King, R G Rozier
The objective of the study was to examine the mediating effect of child dental use on the effectiveness of North Carolina Early Head Start (EHS) in improving oral health-related quality of life (OHRQoL). In total, 479 parents of children enrolled in EHS and 699 parents of Medicaid-matched children were interviewed at baseline when children were approximately 10 mo old and 24 mo later. In this quasi-experimental study, mediation analysis was performed using the counterfactual framework analysis, which employed 2 logit models with random effects: 1) for the mediator as a function of the treatment and covariates and 2) for the outcome as a function of the treatment, mediator, and covariates...
October 2017: JDR Clinical and Translational Research
https://www.readbyqxmd.com/read/28944291/acceptability-of-chairside-screening-for-racial-ethnic-minority-older-adults-a-qualitative-study
#13
A P Greenblatt, I Estrada, E W Schrimshaw, S S Metcalf, C Kunzel, M E Northridge
An aging and more racially and ethnically diverse population, coupled with changes in the health care policy environment, is demanding that the dental profession both redirect and expand its focus. Challenges include providing comprehensive care for patients with complicated medical needs while improving access to care for underserved groups. The purpose of this study is to examine the acceptability of screening for hypertension and diabetes in the dental setting for African American, Puerto Rican, and Dominican older adults who attend senior centers in northern Manhattan, New York City...
October 2017: JDR Clinical and Translational Research
https://www.readbyqxmd.com/read/28879250/dental-care-related-fear-and-anxiety-distress-tolerance-as-a-possible-mechanism
#14
S H Addicks, D W McNeil, C L Randall, A Goddard, L M Romito, C Sirbu, G Kaushal, A Metzger, B D Weaver
Distress tolerance, the degree to which one is able to cope with and endure negative emotional states, has been broadly applied to understand and treat a variety of health (including behavioral) problems, but little is known about its role in oral health care and specifically dental care-related fear and anxiety, making it a novel construct in the oral health care literature. This cross-sectional study examined distress tolerance as a possible predictor of dental fear and anxiety among a sample of adults with and without diagnoses of dental phobia, investigated possible differences in levels of distress tolerance between adults with and without dental phobia, and determined possible associations between distress tolerance and fear of pain, anxiety sensitivity, and depression...
July 2017: JDR Clinical and Translational Research
https://www.readbyqxmd.com/read/28879249/gingival-fluid-inflammatory-biomarkers-and-hypertension-in-african-americans
#15
A Khocht, T Rogers, M N Janal, M Brown
Hypertension and periodontitis are highly prevalent among African Americans. This cross-sectional study investigated the relationships among inflammatory biomarkers in the gingival fluid, periodontitis, and blood pressure in these individuals. Twenty-one subjects who reported a diagnosis of hypertension and a comparison group of 26 nonhypertensive participants were enrolled. All were African Americans, non-cigarette smoking, and free from other systemic illness. Blood pressure and body mass index were assessed...
July 2017: JDR Clinical and Translational Research
https://www.readbyqxmd.com/read/28879248/local-and-plasma-biomarker-profiles-in-localized-aggressive-periodontitis
#16
L S Branco-de-Almeida, Y Cruz-Almeida, Y Gonzalez-Marrero, H Huang, I Aukhil, P Harrison, S M Wallet, L M Shaddox
Localized aggressive periodontitis (LAP) patients possess a systemic hyperinflammatory response after lipopolysaccharide stimulation. However, the levels of inflammatory and bone biomarkers in plasma, as well as possible associations between local and plasma biomarkers, are unknown in LAP. This cross-sectional study aimed to characterize gingival crevicular fluid (GCF) and plasma biomarker profiles in LAP patients, their healthy siblings (HS), and healthy unrelated controls (HC). Fifty-eight LAP subjects, 33 HS, and 49 HC (African Americans, aged 5 to 25 y) were included...
July 2017: JDR Clinical and Translational Research
https://www.readbyqxmd.com/read/28879247/-aggregatibacter-actinomycetemcomitans-in-african-americans-with-localized-aggressive-periodontitis
#17
D Burgess, H Huang, P Harrison, I Aukhil, L Shaddox
This study aims to investigate the prevalence of the highly leukotoxic JP2 sequence versus the minimally leukotoxic non-JP2 sequence of Aggregatibacter actinomycetemcomitans within a cohort of 180 young African Americans, with and without localized aggressive periodontitis (LAP), in north Florida. The study included patients aged 5 to 25 y: 60 LAP patients, 60 healthy siblings (HS), and 60 unrelated healthy controls (HC). Subgingival plaque was collected from LAP sites-diseased (PD ≥5 mm with bleeding on probing) and healthy (PD ≤3 mm with no bleeding on probing)-and from healthy sites of HS and HC...
July 2017: JDR Clinical and Translational Research
https://www.readbyqxmd.com/read/28879246/opioid-analgesic-prescribing-practices-of-dental-professionals-in-the-united-states
#18
C N Steinmetz, C Zheng, E Okunseri, A Szabo, C Okunseri
The prescription of opioid analgesics by dental professionals is widespread in the United States. Policy makers, government agencies, and professional organizations consider this phenomenon a growing public health concern. This study examined trends in the prescription of opioid analgesics for adults by dental professionals and associated factors in the United States. Data from the Medical Expenditure Panel Survey (1996-2013) were analyzed. Descriptive statistics were calculated separately for each year. Logistic regression analyses were conducted to estimate the overall trend during the period with and without adjusting for dental procedures and personal characteristics...
July 2017: JDR Clinical and Translational Research
https://www.readbyqxmd.com/read/28871287/bayesian-analysis-of-the-association-between-family-level-factors-and-siblings-dental-caries
#19
A Wen, R J Weyant, D W McNeil, R J Crout, K Neiswanger, M L Marazita, B Foxman
We conducted a Bayesian analysis of the association between family-level socioeconomic status and smoking and the prevalence of dental caries among siblings (children from infant to 14 y) among children living in rural and urban Northern Appalachia using data from the Center for Oral Health Research in Appalachia (COHRA). The observed proportion of siblings sharing caries was significantly different from predicted assuming siblings' caries status was independent. Using a Bayesian hierarchical model, we found the inclusion of a household factor significantly improved the goodness of fit...
July 2017: JDR Clinical and Translational Research
https://www.readbyqxmd.com/read/28529977/judgment-of-the-quality-of-restorative-care-as-predictors-of-restoration-retreatment-findings-from-the-national-dental-pbrn
#20
J L Riley, G H Gilbert, G W Ford, J L Fellows, B Rindal, V V Gordan
The primary aim of this study was to test the hypothesis that a patient's subjective assessments of the dentist's technical competence, quality of care, and anticipated restoration longevity during a restorative visit are predictive of restoration outcome. This prospective cohort study involved 3,326 patients who received treatment for a defective restoration in a permanent tooth, participated in a baseline patient satisfaction survey, and returned for follow-up. Of the 4,400 restorations that were examined by 150 dentists, 266 (6%) received additional treatment after baseline...
April 2017: JDR Clinical and Translational Research
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