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Stem Cell Investigation

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https://www.readbyqxmd.com/read/28275648/ifn-1-bid-crosstalk-foe-or-friend-to-stem-cells
#1
EDITORIAL
Pratibha Singh, Louis M Pelus
No abstract text is available yet for this article.
2017: Stem Cell Investigation
https://www.readbyqxmd.com/read/28275647/inappropriate-trafficking-of-damaged-mitochondria-in-parkinson-s-disease
#2
EDITORIAL
Chi-Jing Choong, Hideki Mochizuki
No abstract text is available yet for this article.
2017: Stem Cell Investigation
https://www.readbyqxmd.com/read/28275646/producing-tissue-specific-stem-cells-for-regeneration-how-yap-taz-may-prove-useful
#3
EDITORIAL
Steven J Henle, Brian A Link
No abstract text is available yet for this article.
2017: Stem Cell Investigation
https://www.readbyqxmd.com/read/28275645/novel-direct-reprogramming-technique-for-the-generation-of-culture-expandable-cardiac-progenitor-cells-from-fibroblasts
#4
EDITORIAL
Masaaki Ii
No abstract text is available yet for this article.
2017: Stem Cell Investigation
https://www.readbyqxmd.com/read/28275644/schwann-cells-an-emerging-player-in-tissue-regeneration
#5
COMMENT
Adam P W Johnston
No abstract text is available yet for this article.
2017: Stem Cell Investigation
https://www.readbyqxmd.com/read/28275643/a-translational-approach-to-clinical-practice-via-stress-responsive-glucocorticoid-receptor-signaling
#6
COMMENT
Mario F Juruena, Bruno Agustini, Anthony J Cleare, Allan H Young
A recent article by Kwan and colleagues could elegantly demonstrate the necessary interaction between neuronal serotonin (5-HT) systems and the hypothalamic-pituitary-adrenal (HPA) axis through glucocorticoid receptors (GR), producing an adequate stress response, in this case, responding to hypoxia with an increase in hematopoietic stem and progenitor cells (HSPC). There is an intricate system connecting brain, body and mind and this exchange is only possible when all these systems-nervous, endocrine, and immune-have receptors on critical cells to receive information (via messenger molecules) from each of the other systems...
2017: Stem Cell Investigation
https://www.readbyqxmd.com/read/28275642/which-is-better-source-for-functional-hepatocytes
#7
COMMENT
Naoki Tanimizu, Toshihiro Mitaka
No abstract text is available yet for this article.
2017: Stem Cell Investigation
https://www.readbyqxmd.com/read/28275641/the-bone-marrow-microenvironment-driver-of-leukemia-evolution
#8
COMMENT
Mayra Garcia, Ching-Cheng Chen
No abstract text is available yet for this article.
2017: Stem Cell Investigation
https://www.readbyqxmd.com/read/28275640/bringing-light-into-gene-regulation-in-hematopoietic-stem-cells-by-the-mediator-complex
#9
EDITORIAL
Christian Kosan, Maren Godmann
No abstract text is available yet for this article.
2017: Stem Cell Investigation
https://www.readbyqxmd.com/read/28275639/metabolic-plasticity-complements-the-unique-nature-and-demands-of-distinct-pluripotency-states
#10
COMMENT
Mina Popovic, Björn Heindryckx
No abstract text is available yet for this article.
2017: Stem Cell Investigation
https://www.readbyqxmd.com/read/28217710/shedding-light-on-the-darc-knight-as-a-guardian-of-hematopoietic-stem-cell-quiescence
#11
COMMENT
Pniel Nham, Jae-Il Choi, Jin Hur, Sung Hee Baek, Hyo-Soo Kim
No abstract text is available yet for this article.
2017: Stem Cell Investigation
https://www.readbyqxmd.com/read/28217709/redox-homeostasis-unlocking-the-bottleneck-in-glia-to-neuron-conversion
#12
EDITORIAL
Friederike Klempin, Karen Gertz, Golo Kronenberg
No abstract text is available yet for this article.
2017: Stem Cell Investigation
https://www.readbyqxmd.com/read/28217708/aberrant-rna-splicing-and-mutations-in-spliceosome-complex-in-acute-myeloid-leukemia
#13
COMMENT
Jianbiao Zhou, Wee-Joo Chng
The spliceosome, the cellular splicing machinery, regulates RNA splicing of messenger RNA precursors (pre-mRNAs) into maturation of protein coding RNAs. Recurrent mutations and copy number changes in genes encoding spliceosomal proteins and splicing regulatory factors have tumor promoting or suppressive functions in hematological malignancies, as well as some other cancers. Leukemia stem cell (LSC) populations, although rare, are essential contributors of treatment failure and relapse. Recent researches have provided the compelling evidence that link the erratic spicing activity to the LSC phenotype in acute myeloid leukemia (AML)...
2017: Stem Cell Investigation
https://www.readbyqxmd.com/read/28217707/microrna-regulation-of-human-pancreatic-cancer-stem-cells
#14
REVIEW
Yi-Fan Xu, Bethany N Hannafon, Wei-Qun Ding
microRNAs (miRNAs) are a group of small non-coding RNAs that function primarily in the post transcriptional regulation of gene expression in plants and animals. Deregulation of miRNA expression in cancer cells, including pancreatic cancer cells, is well documented, and the involvement of miRNAs in orchestrating tumor genesis and cancer progression has been recognized. This review focuses on recent reports demonstrating that miRNAs are involved in regulation of pancreatic cancer stem cells (CSCs). A number of miRNA species have been identified to be involved in regulating pancreatic CSCs, including miR-21, miR-34, miR-1246, miR-221, the miR-17-92 cluster, the miR-200 and let-7 families...
2017: Stem Cell Investigation
https://www.readbyqxmd.com/read/28217706/there-will-be-blood-hematopoiesis-control-by-mediator-subunit-med12
#15
COMMENT
Thomas G Boyer
No abstract text is available yet for this article.
2017: Stem Cell Investigation
https://www.readbyqxmd.com/read/28217705/med12-in-hematopoietic-stem-cells-cell-specific-function-despite-ubiquitous-expression
#16
EDITORIAL
Maria-Cristina Keightley, Susan K Nilsson, Graham J Lieschke
No abstract text is available yet for this article.
2017: Stem Cell Investigation
https://www.readbyqxmd.com/read/28217704/role-of-adventitial-msc-like-cells-in-chronic-kidney-disease
#17
EDITORIAL
Benedetta Bussolati, Maria Chiara Deregibus, Giovanni Camussi
No abstract text is available yet for this article.
2017: Stem Cell Investigation
https://www.readbyqxmd.com/read/28217703/babesiosis-associated-immune-thrombocytopenia
#18
Roshni Narurkar, Aleksandra Mamorska-Dyga, Anup Agarwal, John C Nelson, Delong Liu
Thrombocytopenia is a common feature of babesiosis. The mechanism for thrombocytopenia in babesiosis remains elusive. We report a case of babesiosis with severe new onset immune thrombocytopenia (ITP). In addition to antibiotics treatment for babesiosis, ITP therapy was administered. ITP in the present case was most likely triggered by the babesia infection. The severity of ITP in this case was not proportional to the severity of parasitemia. The neoantigen triggering the autoimmune response in babesiosis requires further characterization...
2017: Stem Cell Investigation
https://www.readbyqxmd.com/read/28078276/increased-vulnerability-of-photoreceptors-to-aberrant-splicing-highlight-the-utility-of-aon-based-therapy-for-cep290-lca
#19
COMMENT
Shannon E Boye
No abstract text is available yet for this article.
2016: Stem Cell Investigation
https://www.readbyqxmd.com/read/28078275/peptide-vaccination-against-multiple-myeloma-using-peptides-derived-from-anti-apoptotic-proteins-a-phase-i-trial
#20
Nicolai Grønne Jørgensen, Shamaila Munir Ahmad, Niels Abildgaard, Per Thor Straten, Inge Marie Svane, Mads Hald Andersen, Lene Meldgaard Knudsen
The B-cell lymphoma-2 (Bcl-2) family of proteins play a crucial role in multiple myeloma (MM), contributing to lacking apoptosis which is a hallmark of the disease. This makes the Bcl-2 proteins interesting targets for therapeutic peptide vaccination. We report a phase I trial of therapeutic vaccination with peptides from the proteins Bcl-2, Bcl-XL and Mcl-1 in patients with relapsed MM. Vaccines were given concomitant with bortezomib. Out of 7 enrolled patients, 4 received the full course of 8 vaccinations...
2016: Stem Cell Investigation
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