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JAMA Cardiology

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https://www.readbyqxmd.com/read/28636721/evaluating-evolving-technologies-in-a-time-of-rapid-change-the-case-of-transcatheter-aortic-valve-replacement
#1
Robert M Califf
No abstract text is available yet for this article.
June 21, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/28636718/trends-and-outcomes-of-off-label-use-of-transcatheter-aortic-valve-replacement-insights-from-the-ncdr-sts-acc-tvt-registry
#2
Ravi S Hira, Sreekanth Vemulapalli, Zhuokai Li, James M McCabe, John S Rumsfeld, Samir R Kapadia, Mahboob Alam, Hani Jneid, Creighton Don, Mark Reisman, Salim S Virani, Neal S Kleiman
Importance: Transcatheter aortic valve replacement (TAVR) was approved by the US Food and Drug Administration for severe aortic stenosis in patients who cannot undergo surgery and for patients at high operative risk. Use of TAVR for off-label indications has not been previously reported. Objective: To evaluate patterns and adverse outcomes of off-label use of TAVR in US clinical practice. Design, Setting and Participants: Patients receiving commercially funded TAVR in the United States are included in the Transcatheter Valve Therapy Registry...
June 21, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/28636716/wide-complex-tachycardia-in-an-elderly-woman
#3
Andres Enriquez, David S Frankel
No abstract text is available yet for this article.
June 21, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/28636710/off-label-use-of-high-risk-cardiovascular-devices-widening-the-lens
#4
Karen E Joynt, Daniel B Kramer
No abstract text is available yet for this article.
June 21, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/28636701/the-metabolodiuretic-promise-of-sodium-dependent-glucose-cotransporter-2-inhibition-the-search-for-the-sweet-spot-in-heart-failure
#5
Subodh Verma, John J V McMurray, David Z I Cherney
No abstract text is available yet for this article.
June 21, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/28614586/identifying-genotypes-and-phenotypes-of-cardiovascular-diseases-using-big-data-analytics
#6
Chayakrit Krittanawong, Takeshi Kitai
No abstract text is available yet for this article.
June 14, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/28614582/effectiveness-and-safety-of-standard-dose-nonvitamin-k-antagonist-oral-anticoagulants-and-warfarin-among-patients-with-atrial-fibrillation-with-a-single-stroke-risk-factor-a-nationwide-cohort-study
#7
Gregory Y H Lip, Flemming Skjøth, Peter Brønnum Nielsen, Jette Nordstrøm Kjældgaard, Torben Bjerregaard Larsen
Importance: The randomized clinical trials comparing nonvitamin K antagonist oral anticoagulants (NOACs) vs warfarin largely focused on recruiting high-risk patients with atrial fibrillation with more than 2 stroke risk factors, with only the trials testing dabigatran or apixaban including few patients with 1 stroke risk factor. Despite this, regulatory approvals of all NOACs have been based on stroke prevention for patients with atrial fibrillation with 1 or more stroke risk factors...
June 14, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/28614578/introducing-emerging-science-for-the-clinician
#8
Michael S Parmacek
No abstract text is available yet for this article.
June 14, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/28614576/the-hope-and-hype-of-crispr-cas9-genome-editing-a-review
#9
Kiran Musunuru
Importance: Clustered regularly interspaced short palindromic repeats (CRISPR) CRISPR-associated protein 9 (CRISPR-Cas9) has garnered a great degree of attention since its first reported uses in mammalian cells in early 2013 due to its perceived impact with respect to potential research applications and, especially, therapeutic applications. Observations: CRISPR-Cas9 is being widely used in the laboratory and has greatly improved the ability to generate genetically modified animal models of human diseases...
June 14, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/28614562/assessment-and-treatment-of-syncope
#10
Win-Kuang Shen, Robert S Sheldon
No abstract text is available yet for this article.
June 14, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/28614558/burnout-there-s-an-app-for-that-helping-physicians-deal-with-job-related-stress
#11
Noa Holoshitz, Samuel Wann
No abstract text is available yet for this article.
June 14, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/28593325/the-big-bang
#12
Geoffrey Rubin
No abstract text is available yet for this article.
June 7, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/28593301/income-disparities-in-absolute-cardiovascular-risk-and-cardiovascular-risk-factors-in-the-united-states-1999-2014
#13
Ayodele Odutayo, Peter Gill, Shaun Shepherd, Aquila Akingbade, Sally Hopewell, Karthik Tennankore, Benjamin H Hunn, Connor A Emdin
Importance: Large improvements in the control of risk factors for cardiovascular disease have been achieved in the United States, but it remains unclear whether adults in all socioeconomic strata have benefited equally. Objective: To assess temporal trends in 10-year predicted absolute cardiovascular risk and cardiovascular risk factors among US adults in different socioeconomic strata. Design, Setting, and Participants: A cross-sectional analysis was conducted using data on adults 40 to 79 years of age without established cardiovascular disease from the 1999 to 2014 National Health and Nutrition Examination Survey...
June 7, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/28593300/trends-in-cardiovascular-health-of-us-adults-by-income-2005-2014
#14
Adam L Beckman, Jeph Herrin, Khurram Nasir, Nihar R Desai, Erica S Spatz
No abstract text is available yet for this article.
June 7, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/28593298/increased-cardiovascular-risk-associated-with-e-cigarette-use
#15
Fabian Sanchis-Gomar, Giuseppe Lippi, Carme Perez-Quilis
No abstract text is available yet for this article.
June 7, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/28593271/increased-cardiovascular-risk-associated-with-e-cigarette-use-reply
#16
Holly R Middlekauff, Jesus A Araujo
No abstract text is available yet for this article.
June 7, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/28593267/national-trends-in-use-and-outcomes-of-pulmonary-artery-catheters-among-medicare-beneficiaries-1999-2013
#17
Kevin Ikuta, Yun Wang, Austin Robinson, Tariq Ahmad, Harlan M Krumholz, Nihar R Desai
Importance: Recent studies have observed an increase in the rate of pulmonary artery catheter (PAC) use in heart failure admissions. Little is known about the national trends in other previously common indications for PAC placement, PAC use overall, or outcomes associated with PAC placement. Objective: To determine national trends in PAC use overall as well as across sociodemographic groups and key clinical conditions, including acute myocardial infarction, heart failure, and respiratory failure...
June 7, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/28564684/skin-and-vascular-disease-inside-out-outside-in
#18
Calum A MacRae
No abstract text is available yet for this article.
May 31, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/28564682/systolic-blood-pressure-reduction-and-risk-of-cardiovascular-disease-and-mortality-a-systematic-review-and-network-meta-analysis
#19
Joshua D Bundy, Changwei Li, Patrick Stuchlik, Xiaoqing Bu, Tanika N Kelly, Katherine T Mills, Hua He, Jing Chen, Paul K Whelton, Jiang He
Importance: Clinical trials have documented that lowering blood pressure reduces cardiovascular disease and premature deaths. However, the optimal target for reduction of systolic blood pressure (SBP) is uncertain. Objective: To assess the association of mean achieved SBP levels with the risk of cardiovascular disease and all-cause mortality in adults with hypertension treated with antihypertensive therapy. Data Sources: MEDLINE and EMBASE were searched from inception to December 15, 2015, supplemented by manual searches of the bibliographies of retrieved articles...
May 31, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/28564679/difficulties-in-testing-the-instrument-strength-independent-of-direct-effect-assumption-in-mendelian-randomization
#20
Jack Bowden, Stephen Burgess, George Davey Smith
No abstract text is available yet for this article.
May 31, 2017: JAMA Cardiology
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