Lauren Grimm, Chinyere Onyeukwu, Grace Kenny, Danielle M Parent, Jia Fu, Shaurya Dhingra, Emily Yang, James Moy, P J Utz, Russell Tracy, Alan Landay
INTRODUCTION: Neutralizing antibodies have been shown to develop rapidly following SARS-CoV-2 infection, specifically against spike (S) protein, where cytokine release and production is understood to drive the humoral immune response during acute infection. Thus, we evaluated the quantity and function of antibodies across disease severities and analyzed the associated inflammatory and coagulation pathways to identify acute markers that correlate with antibody response following infection...
2022: Pathogens & Immunity