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Revista Brasileira de Reumatologia

Francisco Airton Castro Rocha
Father Cicero Romao Batista is probably the most famous Ceará character of all time. An important protagonist of the Cariri region, situated in the south of Ceara State, in the late nineteenth century and the first third of the twentieth century, Father Cicero had great political and religious activity, as well as other less well-known achievements, for instance, his ecological teachings that led him to be awarded the title of "Patron of Forests", besides an enormous effort and personal sacrifice for the improvement of the conditions of human life...
September 2016: Revista Brasileira de Reumatologia
Verônica Silva Vilela, Giselle Baptista Maretti, Lívia Marques da Silva Gama, Claudia Henrique da Costa, Rogério Lopes Rufino, Roger A Levy
: Systemic sclerosis (SSc) is a chronic autoimmune disease with a high morbidity and mortality. Although cyclophosphamide is effective for severe and refractory cases, there is demand for new treatments. The biological treatment with B-cell depletion with rituximab (RTX) has demonstrated efficacy for this demand in open-label studies. OBJECTIVE: This study was conducted with the aim to retrospectively evaluate all patients who used RTX for the treatment of SSc in our center...
September 2016: Revista Brasileira de Reumatologia
Rafaela Bicalho Viana Macedo, Adriana Maria Kakehasi, Marcus Vinicius Melo de Andrade
A better understanding of the inflammatory mechanisms of rheumatoid arthritis and the development of biological therapy revolutionized its treatment, enabling an interference in the synovitis - structural damage - functional disability cycle. Interleukin 33 was recently described as a new member of the interleukin-1 family, whose common feature is its pro-inflammatory activity. Its involvement in the pathogenesis of a variety of diseases, including autoimmune diseases, raises the interest in the possible relationship with rheumatoid arthritis...
September 2016: Revista Brasileira de Reumatologia
Aline Lauria Pires Abrão, Caroline Menezes Santana, Ana Cristina Barreto Bezerra, Rivadávio Fernandes Batista de Amorim, Mariana Branco da Silva, Licia Maria Henrique da Mota, Denise Pinheiro Falcão
Orofacial manifestations occur frequently in rheumatic diseases and usually represent early signs of disease or of its activity that are still neglected in clinical practice. Among the autoimmune rheumatic diseases with potential for oral manifestations, rheumatoid arthritis (RA), inflammatory myopathies (IM), systemic sclerosis (SSc), systemic lupus erythematosus (SLE), relapsing polychondritis (RP) and Sjögren's syndrome (SS) can be cited. Signs and symptoms such as oral hyposalivation, xerostomia, temporomandibular joint disorders, lesions of the oral mucosa, periodontal disease, dysphagia, and dysphonia may be the first expression of these rheumatic diseases...
September 2016: Revista Brasileira de Reumatologia
Natalia Pereira Machado, Eliana Nogueira, Karen Oseki, Pâmela Carolina Cruz Ebbing, Clarice Silvia Taemi Origassa, Tatiane Mohovic, Niels Olsen Saraiva Câmara, Marcelo de Medeiros Pinheiro
OBJECTIVES: Innate immunity is involved in the physiopathology of ankylosing spondylitis (AS), with the participation of Gram-negative bacteria, modulation of human leukocyte antigen (HLA) B27 and the involvement of pattern recognition receptors, such as Toll-like receptors (TLRs). The aim of this study was to investigate the clinical characteristics and frequency of TLR4 polymorphisms (Asp299Gly and Thr 399Ile) in a cohort of Brazilian patients with AS. METHODS: A cross-sectional study was carried out involving 200 patients with a diagnosis of AS and a healthy control group of 200 individuals...
September 2016: Revista Brasileira de Reumatologia
Karine R Luz, Marcelo M Pinheiro, Giovanna S Petterle, Marla F Dos Santos, Artur R C Fernandes, Jamil Natour, Rita N V Furtado
OBJECTIVE: To propose a novel ultrasound scoring system for hand and wrist joints (US10) for evaluation of patients with early rheumatoid arthritis (RA) and to correlate the US10 with clinical, laboratory and functional variables. METHODS: Forty-eight early RA patients underwent clinical and laboratory evaluations as well as blinded ultrasound (US) examinations at baseline, three, six and 12 months. The proposed US10 system involved the assessment of the wrist, second and third metacarpophalangeal and proximal interphalangeal joints...
September 2016: Revista Brasileira de Reumatologia
Olfat G Shaker, Amina M Alnoury, Gehan A Hegazy, Hemmat E El Haddad, Safaa Sayed, Ahmed Hamdy
BACKGROUND: Rheumatoid arthritis is a widely prevalent autoimmune disorder with suggested genetic predisposition. OBJECTIVES: The aim of this study is to detect the pattern of genetic polymorphism of methylene tetrahydrofolate reductase (MTHFR C677 T and A1298 C), transforming growth factor-β1 (TGF-β1 T869 C) and lymphotoxin-α (LT-α A252G) in patients having rheumatoid arthritis and correlate these patterns to disease activity and serum levels of tumor necrosis factor-alpha (TNF-α), B-Cell Activating Factor (BAFF), and osteopontin...
September 2016: Revista Brasileira de Reumatologia
Silvana Almeida Ribas, Selena Dubois Mendes, Laís Bittencourt Pires, Rafaela Brito Viegas, Israel Souza, Maurício Barreto, Martha Castro, Abrahão Fontes Baptista, Katia Nunes Sá
OBJECTIVE: To check sensitivity and specificity of assessment instruments of QoL in patients with rheumatoid arthritis (RA). METHODOLOGY: Accuracy study in a sample consisting of patients with confirmed diagnosis of RA. QoL questionnaires QV SF-36 (Gold Standard), HAQ and NHP were applied. The Pearson correlation coefficient, ROC curve, AUC and Youden Index (J) were used to analyze the data. RESULTS: This study enrolled 97 individuals with RA...
September 2016: Revista Brasileira de Reumatologia
Ondina Lúcia Ceppas Resende, Maria Tereza Serrano Barbosa, Bruno Francisco Teixeira Simões, Luciane de Souza Velasque
INTRODUCTION: This study, developed in a federal hospital in the city of Rio de Janeiro, has aimed to analyze the social representation of chronic disease and its treatment, in the perspective of adolescents and their caregivers. METHODS: The sample consisted of 31 adolescents (11-21 years) with systemic lupus erythematosus and 19 caregivers (32-66 years), followed in the pediatrics and in the internal medicine outpatient clinics for a period of six months. Data was collected from the free association of words test, using chronic disease and treatment of chronic disease impulses, and later submitted to the Multiple Correspondence Analysis using the R software...
September 2016: Revista Brasileira de Reumatologia
Juliana Maria de Freitas Trindade Costa, Aline Ranzolin, Cláudio Antônio da Costa Neto, Claudia Diniz Lopes Marques, Angela Luzia Branco Pinto Duarte
: Fibromyalgia (FM) and hyperparathyroidism may present similar symptoms (musculoskeletal pain, cognitive disorders, insomnia, depression and anxiety), causing diagnostic confusion. OBJECTIVES: To determine the frequency of asymptomatic hyperparathyroidism in a sample of patients with FM and to evaluate the association of laboratory abnormalities to clinical symptoms. METHODS: Cross-sectional study with 100 women with FM and 57 healthy women (comparison group)...
September 2016: Revista Brasileira de Reumatologia
Aloma S A Feitosa, Jaqueline Barros Lopes, Eloisa Bonfa, Ari S R Halpern
OBJECTIVE: To identify the prognostic factors for conventional physical therapy in patients with chronic low back pain (CLBP). METHODS: Prospective observational study. PARTICIPANTS: One hundred thirteen patients with CLBP selected at the Spinal Disease Outpatient Clinic. MAIN OUTCOME MEASURES: Pain intensity was scored using the Numeric Rating Scale (NRS), and function was measured using the Roland-Morris Disability Questionnaire (RMDQ)...
September 2016: Revista Brasileira de Reumatologia
Susana Cardoso, Daniel Esculpi, Ana Rita Carvalho, Diana R Pereira, Sandra Torres, Francisco Mercado, Fernando Barbosa
In Portugal, it is estimated that chronic pain affects 36.7% of the population, constituting a multifactorial phenomenon with great impact at individual, family, community, and social levels. In the fear-avoidance model of pain, one of the most consistent consensual in the literature, the fear arises as one of the variables that can contribute to the development and maintenance of this condition. Thus, instruments for evaluating the fear of pain, as Fear of Pain Questionnaire (FPQ-III), may be useful in the conceptualization of the subjective experience of pain...
September 2016: Revista Brasileira de Reumatologia
Alessandra Sousa Braz, Carlos Augusto Ferreira de Andrade, Licia Maria Henrique da Mota, Caliandra Maria Bezerra Luna Lima
No abstract text is available yet for this article.
July 2016: Revista Brasileira de Reumatologia
Alexandre Wagner Silva de Souza, Renan de Almeida Agustinelli, Hemerli de Cinque Almeida, Patrícia Bermudes Oliveira, Frederico Augusto Gurgel Pinheiro, Ana Cecilia Diniz Oliveira, Emilia Inoue Sato
OBJECTIVE: To evaluate the extended follow-up data on efficacy and toxicity of leflunomide therapy in Takayasu arteritis (TA) patients previously enrolled in the original open-label study of short-term effects of leflunomide in TA. METHODS: An open-label long-term longitudinal study was performed in TA patients who fulfilled the 1990 American College of Rheumatology criteria for TA and had participated in a previous study that evaluated short-term efficacy of leflunomide in TA...
July 2016: Revista Brasileira de Reumatologia
Marco Felipe Silva, Ana Raquel Feitosa, José A Paz, Nádia Emi Aikawa, Clovis A Silva
Childhood primary angiitis of the central nervous system (cPACNS) is a rare inflammatory brain disease of unknown etiology. Of note, brain hemorrhage has been rarely reported in cPACNS patients, generally associated with a delayed clinical diagnosis, or with a diagnosis only at necropsy. We present the case of a boy with cPACNS that previously suffered an ischemic stroke. At the age of 7 years and 10 months, he presented a sudden and severe headache, vomiting and reduction in consciousness level (Glasgow coma scale 7), requiring prompt tracheal intubation...
July 2016: Revista Brasileira de Reumatologia
Patrícia Becker Engers, Airton José Rombaldi, Elisa Gouvêa Portella, Marcelo Cozzensa da Silva
Several studies show the benefits of including muscle strength and aerobic physical activity in the routine of elderly people. Among the various possibilities of physical activity, the Pilates method has become a popular modality in recent years, through a system of exercises enabling to work the whole body and that corrects posture and realigns the muscles, developing the body stability needed for a healthier life. The aim of this study was to review the current evidence on the effects of the practice of the Pilates method in the elderly...
July 2016: Revista Brasileira de Reumatologia
Odilon Abrahin, Rejane Pequeno Rodrigues, Anderson Carlos Marçal, Erik Artur Cortinhas Alves, Rosa Costa Figueiredo, Evitom Corrêa de Sousa
Osteoporosis is considered a common metabolic bone disease and its prevalence is increasing worldwide. In this context, physical activity has been used as a non-pharmacological tool for prevention and auxiliary treatment of this disease. The aim of this systematic review was to evaluate the effects of cycling and swimming practice on bone mineral density (BMD). This research was conducted in accordance with the recommendations outlined by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses...
July 2016: Revista Brasileira de Reumatologia
Marília M Sampaio-Barros, Liliam Takayama, Percival D Sampaio-Barros, Eloísa Bonfá, Rosa Maria R Pereira
OBJECTIVE: The aim of this study was to analyze the correlation of vitamin D levels with clinical parameters, bone mineral density (BMD), quality of life (QoL) and nailfold capillaroscopy (NC) in patients with diffuse systemic sclerosis (SSc). METHODS: Thirty-eight female patients with diffuse SSc were analyzed regarding 25-hydroxyvitamin D (25OHD) serum levels. At inclusion, organ involvement, autoantibodies, modified Rodnan skin score (mRSS), Medsger Disease Severity Index (MDSI), body mass index (BMI), BMD, NC, Short-Form-36 Questionnaire (SF-36), and Health Assessment Questionnaire (HAQ), were performed through a standardized interview, physical examination and electronic chart review...
July 2016: Revista Brasileira de Reumatologia
Tathiana O Trocoli, Ricardo V Botelho
OBJECTIVE: To evaluate the prevalence of anxiety, depression and kinesiophobia and their association with the symptoms of low back pain. METHODS: A total of 65 patients were divided into three groups: Organic, Amplified Organic and Non-Organic. They answered the Beck Anxiety Inventory, Beck Depression Inventory and Tampa Scale of Kinesiophobia and were evaluated according to their pain level using the Visual Analogic Scale. RESULTS: The average kinesiophobia scores of the patients in the Organic, Amplified Organic and Non-Organic groups were 36...
July 2016: Revista Brasileira de Reumatologia
Marlon van Weelden, Benito Lourenço, Gabriela R Viola, Nadia E Aikawa, Lígia B Queiroz, Clovis A Silva
OBJECTIVE: To evaluate alcohol/tobacco/illicit drug use and sexual function in adolescent juvenile idiopathic arthritis (JIA) and healthy controls. METHODS: 174 adolescents with pediatric rheumatic diseases were selected. A cross-sectional study with 54 JIA patients and 35 controls included demographic/anthropometric data and puberty markers assessments, physician-conducted CRAFFT (car/relax/alone/forget/friends/trouble) screen tool for substance abuse/dependence high risk and a questionnaire that evaluated sexual function, bullying and alcohol/tobacco/illicit drug use...
July 2016: Revista Brasileira de Reumatologia
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