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Open Access Macedonian Journal of Medical Sciences

Patience I Adamu, Pelumi E Oguntunde, Hilary I Okagbue, Olasunmbo O Agboola
BACKGROUND: The effect of insurgencies on a nation regarding the economy, education, health and infrastructure cannot be overemphasised. AIM: This research is therefore focused on analysing the incidence of HIV/AIDS disease in states affected by the activities of the Boko Haram insurgency in Nigeria. MATERIAL AND METHODS: The data collected refer to the period from 2004 to 2017, reporting information on 16,102 patients and including the age, gender, year of diagnosing and status of the patients...
July 20, 2018: Open Access Macedonian Journal of Medical Sciences
Somayeh Lookzadeh, Arda Kiani, Kimia Taghavi, Shirin Kianersi, Habib Emami, Maryam Mirenayat, Atefeh Abedini
INTRODUCTION: Fatigue is one of the common symptoms of sarcoidosis, which occurs in about 50-70% of patients. AIM: Considering that there are no valid Iranian questionnaires for evaluating fatigue in sarcoidosis, in the present study, for the first time, we translated Fatigue Questionnaire into Persean and evaluated its validity and reliability among Iranian patients with sarcoidosis. MATERIAL AND METHODS: In methodological research, English version of Fatigue assessment scale (FAS) 10 items questionnaire which is designed to assess physical or mental fatigue in chronic disease patients, was translated into Persian and back-translated into English...
July 20, 2018: Open Access Macedonian Journal of Medical Sciences
Katayoon Vakilian, Sajedeh Molavi, Ahmad Reza Zamani, Masoumeh Goodarzi
BACKGROUND: Reproductive health programs help women live healthier. Family planning consultation is an important component of reproductive health. A good family planning consultation can increase the use of effective birth control methods and improve the life quality of people, specifically of those at high risk. One of the most effective birth control techniques is an intrauterine device (IUD). AIM: This study was done to investigate the effect of motivational interviewing (MI) on the use of IUD in women at high risk for pregnancy...
July 20, 2018: Open Access Macedonian Journal of Medical Sciences
Biljana Ilievska-Poposka, Maja Zakoska, Karolina Pilovska-Spasovska, Ljiljana Simonovska, Vladimir Mitreski
BACKGROUND: Tuberculosis (TB) is a major health problem in penitentiary institutions (prisons), and its prevalence was reported to be multiple times higher compared to that of the general population. Conditions such as overcrowding, malnutrition and limited access to medical care which often exist in prisons increase the risk of reactivation, transmission and poor prognosis of tuberculosis disease among inmates. AIM: The main objective of this study was to present the epidemiological situation of TB in the prisons from 2008 till 2017 in the Republic of Macedonia (RM)...
July 20, 2018: Open Access Macedonian Journal of Medical Sciences
Fahad M Albakri, Navin Ingle, Mansour K Assery
BACKGROUND: Malocclusion is defined as irregularity of the teeth or a molar relationship between the dental arches beyond the range of what is accepted as normal. AIM: To determine the prevalence of malocclusion among male school children aged 12-15 years old in Riyadh, Saudi Arabia. MATERIALS AND METHODS: Five hundred (500) school children in Riyadh city, Saudi Arabia with an age of 12-15 years participated in this study. The prevalence of malocclusion among the students was determined using a clinical examination form specially prepared for this study...
July 20, 2018: Open Access Macedonian Journal of Medical Sciences
Ali Saafan, Mohamed H Zaazou, Marwa K Sallam, Osama Mosallam, Heba A El Danaf
AIM: To assess the antibacterial competence of 650 nm diode laser, Methylene Blue (MB) and Silver Nano-Particles (Ag NPs) on Streptococcus mutans in biofilm-induced caries models. MATERIAL AND METHODS: One hundred eighty specimens were prepared and equally divided into 6 groups. One group was untreated (control), and the others were subjected to either MB, laser, Ag NPs, the combination of MB and Laser or MB, laser and Ag NPs. RESULTS: Comparison of the log10 mean Colony Forming Units per millilitre (CFU/ml) values of each of the treated 5 groups and the control group was found statistically significant (P-value < 0...
July 20, 2018: Open Access Macedonian Journal of Medical Sciences
Zorica Nanovic, Biserka Kaeva-Jovkovska, Gorica Breskovska, Milena Petrovska
BACKGROUND: Global tuberculosis (TB) epidemic is being driven to an increasing extent by the emergence and spread of drug-resistant strains of Mycobacterium tuberculosis complex (MTBC). We present a case of primary multidrug-resistant tuberculosis (MDR-TB), highlighting Macedonian MDR-TB management issues. CASE REPORT: A 39-year old previously healthy Caucasian male, with no previous history of TB or close contact to TB, was admitted in referral TB-hospital due to respiratory bleeding...
July 20, 2018: Open Access Macedonian Journal of Medical Sciences
Neville Aquilina, Vincent Bugeja, Charmaine Zahra
BACKGROUND: Orbital myositis is an idiopathic, inflammatory, non-infectious condition, typically confined to more than one extraocular muscle and usually targeting young females in their third decade. CASE REPORT: We describe a case of orbital myositis uncommonly afflicting an adult male. He initially presented with a sensation of dizziness when turning his head and mobilising, together with right-sided orbital pain that failed to respond to the vestibular sedative cinnarizine...
July 20, 2018: Open Access Macedonian Journal of Medical Sciences
Tanya Naskova Popova, Atanass Radinov, Konstantin Stavrov, Ivanka Temelkova, Ivan Terziev, Ilia Lozev, Detelina Lukanova, Hristo Mangarov, Uwe Wollina, Georgi Tchernev
BACKGROUND: Modern drugs could sometimes be a good solution even to problematic patients. The cutaneous and systemic forms of the CD30 positive anaplastic large T-cell lymphoma could often be described as a suitable target for therapy with Brentuximab vedotin. CASE REPORT: We present the first case of a Bulgarian patient with a histologically confirmed primary cutaneous T-cell CD30+/ALK- large anaplastic cell lymphoma-cALCL (therapeutically resistant to therapy with Methotrexate, radiation therapy and systemic corticosteroid therapy) who was successfully treated with Brentuximab vedotin...
July 20, 2018: Open Access Macedonian Journal of Medical Sciences
Maria Ferrillo, Alessia Villani, Gabriella Fabbrocini, Massimo Mascolo, Matteo Megna, Claudia Costa, Maddalena Napolitano
BACKGROUND: Subcorneal pustular dermatosis, also known as Sneddon-Wilkinson disease, can be classified as one of the neutrophilic dermatoses together with pyoderma gangrenosum. The development of both SPD and PG in the same patient has rarely been reported and may be a strong indicator of IgA dysglobulinemia. CASE REPORT: We report the case of a 34-year-old woman with a 2-year history of relapsing pustular eruptions mainly affecting the abdomen, gluteus region, elbows, and the extremities...
July 20, 2018: Open Access Macedonian Journal of Medical Sciences
Neville Aquilina, Vincent Bugeja
BACKGROUND: This case report intends to highlight the importance of safeguarding renal function from rhabdomyolysis in neuroleptic malignant syndrome (NMS) by concomitant administration of parenteral fluids at a high rate together with high doses of parenteral loop diuretics (we utilised 6 mg bumetanide daily) and tailed over a few days, in order to preserve glomerular/renal medullary perfusion and nephron function. CASE REPORT: This case describes an elderly lady previously diagnosed with Lewy body dementia who had been started on low dose quetiapine a few days previously and presented with an acute 24 - 48 hour onset of fever, generalised stiffness, rapidly becoming uncommunicable and with high blood pressure...
July 20, 2018: Open Access Macedonian Journal of Medical Sciences
Georgi Tchernev, Ivanka Temelkova
BACKGROUND: Innovations in medicine are often due to the simplicity of a certain activity, interaction, even counteraction, or a mistake leading to a subsequent final optimal outcome. Innovations could also be due to conclusions based on targeted clinical or sporadic, as well as completely random observations. The genius of an approach or statement is often based on the "iron logic", which in turn is based on irrefutable data or facts. These are often observations or results from actions that happen right before our eyes and provide advantages or prerequisites for the better future development of things (in this case, disease) concerning certain groups of people (in these case-patients)...
July 20, 2018: Open Access Macedonian Journal of Medical Sciences
Bilger Çavuş, Özge Çaydaşı, Ahmet Aktan, Ercan Ayaz
BACKGROUND: Brucellosis can lead to different clinical pictures such as hepatomegaly, granulomatous liver disease, hepatic abscess, and it can cause mild hepatic transaminase elevation in the laboratory investigations. CASE REPORT: We found out that the etiologic agent was Brucella in our two cases admitted with acute hepatitis presentation in the investigations conducted. Liver transaminases were as follows for case 1 and case 2; AST: 306/187U/L, ALT: 368/312U/L, ALP: 355/264U/L, GGT: 116/197U/L, LDH: 887/549U/L, respectively...
July 20, 2018: Open Access Macedonian Journal of Medical Sciences
Seyedeh Masoumeh Ahmadi, Amir Jalali, Rostam Jalali
BACKGROUND: Decision making about the type of dialysis in renal failure is a matter of great importance involving the patients, his/her family, and the health care team. Identifying the factors influencing decision making for undergoing peritoneal dialysis (PD) helps the development of this therapeutic method in patients. AIM: The present study aims at explaining the factors influencing decision making about undergoing PD in End Stage Renal Failure patients. METHOD: The present study is a qualitative research, which used content analysis method...
July 20, 2018: Open Access Macedonian Journal of Medical Sciences
Samaneh Kouzegaran, Mohammad Ali Zamani, Reza Faridhosseini, Houshang Rafatpanah, Abdolrahim Rezaee, Hadis Yousefzadeh, Rahman Movahed, Farahzad Jabbari Azad, Hooman Tehrani
BACKGROUND: Allergic rhinitis is one of the most common allergic diseases and characterised by sneezing, rhinorrhea, nasal congestion and nasopharyngeal itching. Subcutaneous immunotherapy (SCIT) for specific allergens is an effective treatment and induces the inhibitory effect of T regulatory lymphocytes and decreases clinical symptoms in allergic rhinitis. AIM: In this study effect of subcutaneous immunotherapy with specific allergens on clinical symptoms and T regulatory and T Helper cells cytokines, in patients with allergic rhinitis are evaluated...
July 20, 2018: Open Access Macedonian Journal of Medical Sciences
Hafza Tola, Mohammed Abbas, Elsir Abu Alhassan, Nassr Eldin Shrif, Mohammed Rida
BACKGROUND: The diagnosis of polycystic ovary syndrome (PCOS) is not an easy procedure, as the signs and symptoms are heterogeneous and of undefined aetiology. AIM: This study is aimed to evaluate serum anti-Mullerian hormone (AMH) level and luteinizing hormone (LH)/folic stimulating hormone (FSH) ratio in women with PCOS in Sudan and to assess the diagnostic efficiency for the diagnosis of PCOS. METHODS: In a case-control study, Serum AMH, LH, FSH was measured in the early follicular phase from Sudanese patients (N = 230) with PCOS and100 controls...
July 20, 2018: Open Access Macedonian Journal of Medical Sciences
Khadijeh Haji Naghi Tehrani
BACKGROUND: The use of the MRI method has opened up a new perspective on pathogenesis, diagnosis and treatment of brain lesions. AIM: Therefore, this study aimed to evaluate the prevalence of brain subclinical lesions in MRI images of migraine patients. METHODS: This cross-sectional study was conducted on 300 patients with a migraine referred to Baqiyatallah and Amir Al-Momenin Hospitals from 2005 to 2006. We measured the relationship between the results of MRI and the type of brain subclinical lesion by indices such as age, gender, type of a migraine, the number of migraine attacks, blood pressure and heart diseases, cholesterol, diabetes and thyroid diseases...
July 20, 2018: Open Access Macedonian Journal of Medical Sciences
Atoosa Gharib, Mojgan Forootan, Marjan Sharifzadeh, Saied Abdi, Mohammad Darvishi, Ahmad Eghbali
BACKGROUND: Gastric reflux is one of the most important causes of the referral of patients to the internal clinic, which in some cases causes problems for patients due to resistance to common treatments. Therefore, timely diagnosis and treatment of this group of patients are very important. AIM: The purpose of the present study was to determine the off-proton pump inhibitor (off-PPI) 24 h pH-impedance analyses in patients with refractory gastroesophageal reflux disease (GERD) attending to Taleghani Hospital since 2009 to 2017...
July 20, 2018: Open Access Macedonian Journal of Medical Sciences
Aida Mossaad, Amr Kotb, Moustapha Abdelrahaman, Hatem Al Ahmady
BACKGROUND: Postoperative scarring is a common cause of patients dissatisfaction. Several modalities have been developed to overcome such a problem following surgical repair. Despite precise surgical technique, still, some scars would remain over the time, mostly due to the weak formation or inadequately replaced collagen fibres in the underneath dermis especially those following unilateral or bilateral cleft lip repair surgery. AIM: of this study is to evaluate whether a 10,600 nm fractional ablative carbon dioxide (CO2 ) used early during the healing period would result in better postoperative scars...
July 20, 2018: Open Access Macedonian Journal of Medical Sciences
Abdollah Hajivandi, Hamid Reza Ghafarian Shirazi, Seyed Hassan Saadat, Mohammad Chehrazi
AIM: Verification bias is one of the major problems encountered in diagnostic accuracy studies. It occurs when a standard test performed on a non-representative subsample of subjects which have undergone the diagnostic test. In this study we extend a Bayesian model to correct this bias. METHODS: The study population is patients that have undergone at least two repeated failed IVF/ICSI (in vitro fertilization/intra cytoplasmic sperm injection) cycles. Patients were screened using ultrasonography and those with polyps were recommended for hysteroscopy...
July 20, 2018: Open Access Macedonian Journal of Medical Sciences
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