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Open Access Macedonian Journal of Medical Sciences

Zaim Gashi, Aida Ferri Polloshka, Arber Veliu, Fisnik Kurshumliu, Elton Bahtiri
The patient, a 40-year-old male, was referred to our clinic with intermittent nausea, vomiting and symptomatic anemia for 4 months. Notable hematological indices were low hemoglobin levels of 9.6 g/dl and hematocrit levels of 35.8%, while after receiving two units of concentrated red blood cells, at discharge; they achieved levels of 15.2 g/dl and 42.3%, respectively. Esophagogastroduodenoscopy revealed a 3 cm antral pedunculated polyp, prolapsing into pylorus thus causing intermittent pyloric obstruction and anemia...
December 15, 2017: Open Access Macedonian Journal of Medical Sciences
Milena Cojić, Ljiljana Cvejanov-Kezunović
Subclinical hypothyroidism represents a state with increased values of thyroid stimulating hormone (TSH) and normal values of thyroxine (T4) and triiodothyronine (T3). The disorder is asymptomatic, and the diagnosis is made based on the results of laboratory findings when the level of TSH reaches values above 4.0 mU/l. It is still subject to debate whether patients with subclinical hypothyroidism are at increased risk of cardiovascular disease, neuropsychiatric and neuromuscular disorders. Studies have shown that the appearance of general symptoms and complications are more common in patients whose values of TSH are above 10 mU/l...
December 15, 2017: Open Access Macedonian Journal of Medical Sciences
Naser Ramadani, Valbona Zhjeqi, Merita Berisha, Rina Hoxha, Ilir Begolli, Drita Salihu, Pranvera Krasniqi
AIM: To determine the characteristics of the Socio-medical profile of road traffic accidents in Kosovo, between 2010 and 2015 year. STUDY DESIGN: Retrospective study. METHODS: A descriptive method based on the database of road traffic accidents from the National Police of Kosovo. RESULTS: In Kosovo for the period 2010-2015, on average, the yearly number of road traffic accidents is 18437 with mortality rate 7.4 per 100000 and lethality of 1...
December 15, 2017: Open Access Macedonian Journal of Medical Sciences
Abdulrahman A Al-Mohaimeed, Abeer Abuzeid Atta Elmannan
BACKGROUND: Obesity has become a global health threat. Saudi Arabia ranks among the countries with high obesity and overweight rates. This study aims to explore experiences of Saudi people with overweight or obesity with a particular focus on the perceived barriers and motivators to weight loss. MATERIAL AND METHODS: We used a qualitative approach to recruiting a purposive sample using maximum variation sampling technique. Those who had previously attempted weight loss at least once were included in the study...
December 15, 2017: Open Access Macedonian Journal of Medical Sciences
Mitar Lutovac, Olga V Popova, Zoran Jovanovic, Hatidza Berisa, Radoman Kristina, Sonja Ketin, Marko Bojic
AIM: The paper presents research on the most common causes of exposure that leads to disorders of cholinesterase activity, as well as an overview of the results of cholinesterase activity with the poisoned people. MATERIAL AND METHODS: In a group of 35 acute poisoned patients by organophosphate compounds has led to inhibition of AchE. A total number of examined workers are 175 in the chemical industry and agricultural production in the area of Rasina District-Serbia...
December 15, 2017: Open Access Macedonian Journal of Medical Sciences
Badriah Ali Alansi, Hytham Bahaeldin Mukhtar, Maher Ahmad Alazizi, Amjad Ahmad Zuiran, Areej Mohammed Al-Atawi, Badriah Abdulrahman Al-Sabah, Shrooq Salem Al-Yami
AIM: To investigate risk factors for early preterm birth. METHODS AND MATERIAL: A retrospective comparative study was conducted at Tabuk, Kingdom of Saudi Arabia during the period from January to December 2010. Five hundred and ninety-five patient's files and delivery registry logbooks were reviewed, the following information was collected; demographic data, current and past obstetric histories. Then the early and late preterm births were compared for various risk factors...
December 15, 2017: Open Access Macedonian Journal of Medical Sciences
Anthonia Ikpeme, Nchiewe Ani, Boniface Ago, Emmanuel Effa, Omofolasade Kosoko-Lasaki, Andrew Ekpenyong
AIM: This paper examines the activities of mobile services units including ultrasound services in rural and urban communities in the Calabar region of South-South, Nigeria. MATERIALS AND METHODS: Consenting individuals were invited and attended five medical outreach activities in rural and urban areas of the Calabar region between January and June 2016. Abdomino-pelvic scans were done. Subsequently the results were analyzed. RESULTS: Five hundred and seventy-four (574) individuals had Abdomino-pelvic scans done, using a curvilinear probe to assess the abdomino-pelvic organs...
December 15, 2017: Open Access Macedonian Journal of Medical Sciences
Tanja Makazlieva, Olivija Vaskova, Venjamin Majstorov, Sinisha Stojanoski, Nevena Manevska, Rubens Jovanovic
BACKGROUND: Thyroid carcinomas (TC) are the most common endocrine malignancies. In some parts of the world, the incidence of TCs has increased over the past few decades, especially in females according to some studies. AIM: We have set as the objective for our study to analyse the demographic, ultrasound features, thyroid hormonal status and frequency of thyroid carcinomas in the Republic of Macedonia according to histopathological type. MATERIALS AND METHODS: Retrospective analysis of medical data from all diagnosed and treated patients with TC at the Institute of Pathophysiology and Nuclear Medicine for the period 1999-2010 was performed...
December 15, 2017: Open Access Macedonian Journal of Medical Sciences
Vesna Korunoska-Stevkovska, Ljuben Guguvcevski, Zaklina Menceva, Nikola Gigovski, Aneta Mijoska, Julijana Nikolovska, Emilija Bajraktarova-Valjakova
BACKGROUND: The success of prosthetic rehabilitation in patients with removable dentures depends on the achievement of the aesthetics, phonetics and most of all, proper use in the mastication process. All the patients that receive removable prostheses need a feeding education program. They must cut the food into smaller pieces, extend the length of time necessary for chewing and place the food upon both the right and left sides of the mouth at once. Bilaterally chewing with dentures will contribute to increased efficiency and denture stability during mastication...
December 15, 2017: Open Access Macedonian Journal of Medical Sciences
Hani El Nahass, Nada Nour El Din, Sherine Adel Nasry
AIM: The current study was designed to investigate the effectiveness of locally applied Strontium ranelate to induce bone formation. MATERIALS AND METHODS: Forty-eight female rats were divided into six groups (eight rats in each group): The three test groups included Strontium (SR) 2.5 mg, 5 mg and 10 mg that was dissolved in methylcellulose gel. The control groups included methylcellulose, simvastatin 5 mg and a negative control where the defect was left to heal without any intervention...
December 15, 2017: Open Access Macedonian Journal of Medical Sciences
Mitar Lutovac, Olga V Popova, Gordana Macanovic, Radoman Kristina, Bojana Lutovac, Sonja Ketin, Rade Biocanin
BACKGROUND: Dental erosion is a common problem in modern societies, owing to the increased consumption of acid drinks such as soft drinks, sports drinks, fruit juice. Examining the enamel surface with the Atomic Force Microscopy (AFM) enables more precise registering and defining the changes of enamel surface structure and microhardness. This method can be used to compare the efficiency of application of different preventive and therapy materials and medicaments in dentistry. The chronic regular consumption of low pH cola drinks encouraged the erosion of the teeth...
December 15, 2017: Open Access Macedonian Journal of Medical Sciences
Ljuben Guguvcevski, Nikola Gigovski, Aneta Mijoska, Katerina Zlatanovska, Ana Arsova-Gigovska
BACKGROUND: The term decreased occlusal vertical dimension refers to the reduced distance between two anatomical points while the teeth are in a state of occlusion. The development of this situation is about some parafunctional activities of the masticatory system. AIM: To evaluate the value of decreased occlusal vertical dimension in cases with temporomandibular disorder and to follow up the influence of corrective treatment with occlusal splints and definitive prosthetic construction upon the elimination of clinical symptoms...
December 15, 2017: Open Access Macedonian Journal of Medical Sciences
Rezvan Talaee, Zohreh Hajheydari, Ahmad Yeganeh Moghaddam, Seyyed Alireza Moraveji, Bentolhoda Fatahi Ravandi
BACKGROUND: Psoriasis is a common inflammatory papulosquamous disease of the skin with unknown aetiology that may be associated with the abnormal T-cell function. AIM: This study was aimed to determine the prevalence of oral mucosal lesions and their associations with severity of psoriasis in psoriatic patients attending the dermatologic clinic of Shahid Beheshti Teaching Hospital at Kashan, Iran. METHODS: In this cross-sectional descriptive analytic study, all consecutive patients with psoriasis who referred to the dermatologic clinic at the Shahid Beheshti Hospital of Kashan University of Medical Sciences in Kashan City/ Iran were enrolled...
December 15, 2017: Open Access Macedonian Journal of Medical Sciences
Kalina Trifonova, George Jordanoff, Valentin Stoyanov, Kiril Slaveykov
BACKGROUND: Alport syndrome is a progressive genetic disease which is characterised by glomerulonephritis, sensorineural deafness and ocular abnormalities. We aimed to present a clinical case of a patient with Alport syndrome with spontaneous anterior lens capsule rupture. CASE REPORT: A 16-year-old male with histologically proven Alport syndrome was hospitalised in the Department of Ophthalmology, University Hospital "Prof. Stoyan Kirkovich", Stara Zagora with low vision, pain, redness, high IOP and rupture of the anterior lenticular capsule of the right eye...
December 15, 2017: Open Access Macedonian Journal of Medical Sciences
Georgi Tchernev, Anastasiya Chokoeva, Lyubomira Victor Popova
BACKGROUND: Malignant melanoma is a disease which has a cutaneous origin in 90% of the patients, but in rare cases, it could be discovered as secondary deposits with unknown primary site. Metastatic Malignant Melanoma occurs without a primary site in about 3% of all melanoma patients, and it could be divided into two main groups: metastatic lymph nodes' involvement or non-lymph nodes disease. The lack of unified classification and staging system, provided by AJCC (2009), as well as the lack for curtain diagnostic and therapeutic protocol, prompt us to raise the question what is the right way to precede in cases of metastasis of the lymph nodes, without evidence of a primary tumour? CASE REPORT: We report a case of 67-years- old woman who presented in the dermatology clinic after a surgical removal of an enlarged lymph node in her left femoral area, verified histologically as a metastasis of melanoma...
December 15, 2017: Open Access Macedonian Journal of Medical Sciences
Walaa A Kamel, Jasem Y Al-Hashel, K John Alexander, Fathi Massoud, Fatima Al Shawaf, Ibtisam E Al Huwaidi
AIM: To report a potential association of thrombosis, thrombocytopenia with iron deficiency anaemia. CASE REPORT: A 43-year-old female experienced an episode of a headache, with bilateral papilledema by neurological examination, magnetic resonance venography (MRV) brain showed cerebrovenous thrombosis (CVT), iron deficiency anaemia and thrombocytopenia by blood investigations, that was treated with iron supplementations and anticoagulation. CONCLUSION: In this patient, cerebrovenous thrombosis (CVT) was discovered in a patient with thrombocytopenia and iron deficiency anaemia and treated with iron supplements and anticoagulation, we concluded that thrombocytopenia is not a protective factor against thrombosis especially with iron deficiency anaemia...
December 15, 2017: Open Access Macedonian Journal of Medical Sciences
Georgi Tchernev, Liubomira Victor Popova
BACKGROUND: Although PET-scan is an advanced, innovative and widely used method for monitoring patients with different types of cancer diseases, it is important to note that its application in patients with cutaneous melanoma is limited and should be reconsidered. CASE REPORT: To affirm this new statement, we are presenting a case from our clinical practice of a patient with melanoma of the interdigital space (with resected in sano primary melanoma and performed complete lymphadenectomy) that showed locoregional and systemic progression in two months post operation...
December 15, 2017: Open Access Macedonian Journal of Medical Sciences
Maryam Jameshorani, Saba Sayari, Narjes Kiahashemi, Nima Motamed
BACKGROUND: Diabetes mellitus is a progressive disorder that often requires combination therapy. AIM: This study aimed to compare and study of add-on sitagliptin versus pioglitazone in patients with type 2 diabetes inadequately controlled with metformin. METHODS: This 12-week, randomised, open-label and single centre study compared sitagliptin (100 mg daily, n = 80) and pioglitazone (30 mg daily, n = 80) in type 2 diabetic patients whose disease was not adequately controlled with metformin...
December 15, 2017: Open Access Macedonian Journal of Medical Sciences
Ridha Dharmajaya, Dina Keumala Sari, Ratna Akbari Ganie
BACKGROUND: Herniated Nucleus Pulposus (HNP) is the prolapse of the intervertebral disk through a tear in the annulus fibrosus. This causes nerve root compression with clinical pain manifestation and affects the quality of sleep. AIM: The aim of this study was find out the comparison in the quality of sleep between before (pre) and after (post) surgery cervical HNP patients. METHODS: This study was a retrospective cohort study. Ninety patients were asked to complete the Pittsburgh Sleep Quality Index (PSQI) questionnaire...
December 15, 2017: Open Access Macedonian Journal of Medical Sciences
Radha Siregar, Sri Purnama, Salia Lakswinar
BACKGROUND: One of the treatments for leukaemia is chemotherapy. Side effects and toxicity of this treatment can be seen on the skin, adnexal, and mucous membranes. They might increase potential hydrogen (pH) value on the skin surface, therefore, disrupting epidermal barrier defences. AIM: To describe the pH of the skin in children with leukaemia who received chemotherapy. SUBJECT AND METHOD: This study was an observational descriptive, cross-sectional study, conducted from March until December 2016 with 32 children with leukaemia who treated at Haji Adam Malik General Hospital, Medan as subjects...
December 15, 2017: Open Access Macedonian Journal of Medical Sciences
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