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Open Access Macedonian Journal of Medical Sciences

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https://www.readbyqxmd.com/read/29123574/sentinel-lymph-node-detection-in-colorectal-cancer-first-experience
#1
Sinisa Stojanoski, Nevena Manevska, Svetozar Antovic, Daniela Pop-Gjorcheva, Olivija Vaskova, Daniela Miladinova, Magdalena Mileva
BACKGROUND: Colorectal cancer (CRC) is the second commonest cancer in women, the third in men, being the fourth commonest cause of cancer death. The most important factor for prognosis and staging in CRC patients is the status of the regional lymph nodes (LN). AIM: To implement the method for sentinel lymph node (SLN) detection in CRC patients using radiocolloid, and test its detection rate, sensitivity, accuracy, negative predictive value and the possibility for upstaging...
October 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29123573/conformity-index-and-homogeneity-index-of-the-postoperative-whole-breast-radiotherapy
#2
Deva Petrova, Snezana Smickovska, Emilija Lazarevska
BACKGROUND: The treatment of breast cancer involves a multidisciplinary approach in which radiotherapy plays a key role. AIM: The conformity index and the homogeneity index are two analysis tools of a treatment plan using conformal radiotherapy. The purpose of this article is an analysis of these two parameters in the assessment of the treatment plans in 58 patients undergoing postoperative radiotherapy of the whole breast. MATERIALS AND METHODS: All 58 patients participating in the study had a conservatively treated early-stage breast cancer...
October 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29104697/novel-surgical-approach-in-cutaneous-melanoma-patients-daring-ideas-are-like-chessmen-moved-forward-they-may-be-beaten-but-they-may-start-a-winning-game
#3
Georgi Tchernev
For the first time, but again, we propose the idea of a one-step melanoma surgery as a "golden, unified standard" that should be at least discussed and, possibly accepted shortly as the "gold standard" for the treatment of patients with skin melanomas. Critical points or comments have been made to the current melanoma's treatment approach, which has been "transcendently followed" for years and which, according to some colleagues, is not logically justified. This approach needs serious changes, the only goal of which is to achieve a better outlook for the patients...
October 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29104696/ulcerated-metatypical-basal-cell-carcinoma-of-the-forehead
#4
Jose Cardoso, Uwe Wollina, Georgi Tchernev
An 81-year-old male presented with an ulcerated lesion on the frontal area. The lesion had started three years before with a small ulceration and was initially treated with a cream of betamethasone and fusidic acid twice daily for several months. The clinical impression was ulcerated basal cell carcinoma (BCC). The histopathological findings after surgical excision were consistent with metatypical or basosquamous carcinoma. The importance of metatypical and basosquamous carcinomas is their potential for a more aggressive behaviour than conventional BCC, both regarding local recurrences and metastatic disease...
October 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29104695/multiple-primary-acral-lentiginous-melanomas-mpalm
#5
Miriam González, Georgi Tchernev, Anastasiya Atanasova-Chokoeva, Katlein França, Torello Lotti
We present a rare case of a patient with multiple primary acral lentiginous melanomas of the foot. We would like to highlight the importance of whole-skin examination in all patients, even by the general practitioners, aiming the maximal early detection of acral lentiginous melanomas, considering their rapid progression, early metastatic spread and extremely poor prognosis. It can be extrapolated from current literature; however, that appropriate management of these patients, including staging work and surgical intervention, is to be determined by the individual characteristics of the melanoma and the patient's concomitant risk factors, if any...
October 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29104694/health-effects-associated-with-exposure-to-anesthetic-gas-nitrous-oxide-n2o-in-clinical-hospital-shtip-personel
#6
Bilijana Eftimova, Marija Sholjakova, Dejan Mirakovski, Marija Hadzi-Nikolova
AIM: To show certain health effects associated with acute and chronic exposure to nitrous oxide of staff of the Department of Anaesthesiology and Intensive Care at the Clinical Hospital in Shtip. METHODS: A transversal study was conducted, that include 43 health workers (23 - exposed and 20 - unexposed). Personal exposure to nitrous oxide for this group members was assessed through continuous measurement over 8 hours shift within breathing zone of the subjects involved, using handheld electrochemical instrument with datalogging option direct...
October 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29104693/exercise-participation-motives-and-engaging-in-sports-activity-among-university-of-ljubljana-students
#7
Katja Cerar, Miran Kondrič, Nicolae Ochiana, Joško Sindik
AIM: The main aim of this study was to examine differences in sport participation motives, the frequency of engaging in sports activities according to gender, region and field of study, but also the association between the incidence of engaging in sports activity and the motivation for sports activity of students at the University of Ljubljana. MATERIAL AND METHODS: Five thousand two hundred seventy-one students completed The Exercise Motivations Inventory (EMI-2), with additional questions about 12 socio-demographic parameters...
October 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29104692/nitrous-oxide-exposure-of-health-care-personnel-in-the-operating-rooms-and-intensive-care-units-in-hospitals-in-macedonia
#8
Biljana Eftimova, Dejan Mirakovski, Marija Sholjakova, Marija Hadzi-Nikolova
AIM: To determine average personal exposure to nitrous oxide for anaesthesiologists and nurses working in operating rooms (ORs) and intensive care units (ICU) in Clinical Hospital in Shtip, ENT University Clinic in Skopje and General Hospital in Kochani. METHODS: To determine TWA exposure nitrous oxide concentration was continuously measured over 8 hours shift within breathing zone of the subjects involved, using the handheld electrochemical instrument with data logging option...
October 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29104691/complete-dentures-fabricated-with-cad-cam-technology-and-a-traditional-clinical-recording-method
#9
Nadica Janeva, Gordana Kovacevska, Edvard Janev
The introduction of computer-aided design/computer-aided manufacturing (CAD/CAM) technology into complete denture (CD) fabrication ushered in a new era in removable prosthodontics. Commercially available CAD/CAM denture systems are expected to improve upon the disadvantages associated with conventional fabrication. The purpose of this report is to present the workflow involved in fabricating a CD with a traditional clinical recording method and CAD/CAM technology and to summarize the advantages to the dental practitioner and the patient...
October 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29104690/frequency-of-symptoms-of-temporomandibular-disorders-among-prishtina-dental-students
#10
Teuta Bicaj, Kujtim Shala, Teuta Pustina Krasniqi, Enis Ahmedi, Linda Dula, Zana Lila-Krasniqi
BACKGROUND: Early diagnosis of temporomandibular disorders (TMD) is important for prevention of greater damages of the parts of the oro-facial system. There are early symptoms that can be used as predictors of TMD. AIM: The study aimed to assess the frequency of the symptoms of TMD among dental students. METHODS: Total number of 166 respondents, all undergraduate dental students, (84 female, 82 male), mean age 22, participated in this study...
October 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29104689/differences-of-tooth-colorimetric-parameters-l-a-b-depended-on-age
#11
Teuta Pustina Krasniqi, Zana Lila-Krasniqi, Nexhmije Ajeti, Kujtim Shala, Teuta Bicaj, Linda Dula
AIM: The study aimed to analyse differences in colourimetric parameters L*a*b*, depended on age. MATERIAL AND METHODS: In this study were included 255 subjects with age interval from 20 to 49 years. The subjects were divided into three groups, as follows: in the younger group were 20 to 29 years of age, those in the middle group 30 to 39 years and older group 40 to 49 years. The overall number of analysed teeth in the intercanine sector of the maxilla was 2295. The colour of the teeth was measured using the spectrophotometer VITA Easyshade...
October 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29104688/one-step-surgery-for-cutaneous-melanoma-we-cannot-solve-our-problems-with-the-same-thinking-we-used-when-we-created-them
#12
Georgi Tchernev
One step melanoma surgery is, in fact, an innovative combined method for diagnosis and treatment of cutaneous melanoma (at the same time). The methodology allows an accurate assessment of the actual status of the affected patients by 1) clinical status, dermatoscopy, high-frequent ultrasonography (HFUS) of the pigmented lesion (eventually in combination with normal lymph nodes ultrasonography), followed by a single surgical intervention. Within this intervention, the primary tumour is removed with the appropriate surgical field, with or without parallel detection and draining lymph node biopsy (depending on the established tumour thickness)...
October 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29104687/traumatic-transient-herniation-concomitant-with-tonsillar-hemorrhagic-contusion-in-a-child
#13
Ahmet Öğrenci, Orkun Koban, Murat Ekşi, Onur Yaman, Sedat Dalbayrak
Downward displacement of cerebellar tonsils more than 5 mm below the foramen magnum is named as Chiari type I malformation and named benign tonsillar ectopia if herniation is less than 3 mm. It does not just depend on congenital causes. There are also some reasons for acquired Chiari Type 1 and benign tonsillar ectopia/herniation. Trauma is one of them. Trauma may increase tonsillar ectopia or may be the cause of new-onset Chiari type 1. The relationship between the tonsil contusion and its position is unclear...
October 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29104686/liposuction-assisted-lipoma-removal-option-or-alternative
#14
Igor Peev, Liljana Spasevska, Elizabeta Mirchevska, Smilja Tudzarova-Gjorgova
BACKGROUND: Lipomas are the most frequent soft -tissue tumors arising from adipose tissue. Traditionally, open surgery is a mainstay of their treatment. Recently, new treatment modalities emerge in order to decrease morbidity, to increase satisfaction rate in patents, but not to raise recurrence risk at the same time. AIM: The aim of this article is to present our experience with liposuction assisted lipoma removal in terms of efficacy, complications, risk of recurrence and patient satisfaction...
October 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29104685/the-use-of-computed-tomography-in-the-diagnosis-of-fatty-liver-and-abdominal-fat-distribution-among-a-saudi-population
#15
Gasim Ibrahim Gasim, Fahd Mohamed Elshehri, Mahmoud Kheidr, Fahad Khalid Alshubaily, ElZaki Mohamed ElZaki, Imad R Musa
BACKGROUND: The pandemic of obesity is striking heavily worldwide and particularly among the affluent Gulf States where it is expected to continue to rise along with its complications. AIM: To examine the link between liver fat infiltration and abdominal fat amount using plain computer-assisted tomography (CT). METHODS: Fifty patients visiting the obesity clinic of "King Fahd Specialist Hospital" or Dr Suliman Alhabeeb Hospital between January 2015 and April 2016 were included...
October 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29104684/effect-of-flunarizine-on-serum-glutamate-levels-and-its-correlation-with-headache-intensity-in-chronic-tension-type-headache-patients
#16
Khairul Putra Surbakti, Hasan Sjahrir, Rosita Juwita-Sembiring, Erna Mutiara
BACKGROUND: Some of the excitatory neurotransmitters including glutamate have been suggested to be involved in headache pathophysiology. To our knowledge, there is a lack of publication about flunarizine efficacy in chronic tension-type headache (CTTH) treatments and the roles of glutamate in CTTH pathophysiology. AIM: This study aimed to investigate the flunarizine effect on serum levels of glutamate and its correlation with headache intensity based on the Numeric Rating Scale for pain (NRS) scores in CTTH patients...
October 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29104683/relationship-of-cord-blood-immunoglobulin-e-and-maternal-immunoglobulin-e-with-birth-order-and-maternal-history-of-allergy-in-albanian-mother-neonate-pairs
#17
Hatixhe Latifi-Pupovci, Violeta Lokaj-Berisha, Besa Lumezi
BACKGROUND: Previous studies reported that familial factors such as birth order and mothers atopy might influence cord blood levels and development of allergies. AIM: The aim of the study was to evaluate the relationship of cord blood IgE and maternal IgE with birth order and mothers history of allergy in Albanian mother/neonate pairs. MATERIAL AND METHODS: Study population represented 291 mother-infant pairs. Mothers were interviewed with a questionnaire for personal history of allergy and pregnancy history whereas serum IgE levels were determined using sandwich IRMA assay...
October 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29104682/the-necessity-of-follow-up-brain-computed-tomography-scans-is-it-the-pathology-itself-or-our-fear-that-we-should-overcome
#18
Ahmet Öğrenci, Orkun Koban, Murat Ekşi, Onur Yaman, Sedat Dalbayrak
AIM: This study aimed to make a retrospective analysis of pediatric patients with head traumas that were admitted to one hospital setting and to make an analysis of the patients for whom follow-up CT scans were obtained. METHODS: Pediatric head trauma cases were retrospectively retrieved from the hospital's electronic database. Patients' charts, CT scans and surgical notes were evaluated by one of the authors. Repeat CT scans for operated patients were excluded from the total number of repeat CT scans...
October 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29104681/association-between-beta-sympathomimetic-tocolysis-and-risk-of-autistic-spectrum-disorders-behavioural-and-developmental-outcome-in-toddlers
#19
Mengühan Araz Altay, Işık Görker, Rakhshanda Aslanova, Leyla Bozatlı, Nesrin Turan, Petek Balkanlı Kaplan
AIM: To investigate whether maternal intravenous beta-mimetic tocolytic therapy increases the risk of autistic spectrum disorders (ASD) and poorer behavioural and developmental outcomes. METHOD: Our study is a prospective case-control study among 90 children between 1.5 and three years old. Cases (n = 46) were toddlers with betamimetic tocolytic exposure; control group toddlers (n = 44) were tocolytic untreated. Treated and untreated groups were also divided into subgroups: term and preterm delivered...
October 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29104680/c-reactive-protein-concentrations-among-crop-and-dairy-farmers-with-stable-chronic-obstructive-pulmonary-disease
#20
Saso Stoleski, Jordan Minov, Jovanka Karadzinska-Bislimovska, Dragan Mijakoski, Lütfiye Tutkun
AIM: To assess the mean serum C-reactive protein concentrations among farmers and office controls, and further examined its relation to exposure duration, smoking habit, as well as presence or absence of COPD. METHODS: A cross-sectional survey was performed including examined group (EG), composed of agricultural workers (87 crop - EG1 and 83 dairy farmers - EG2), and control group (CG) composed by 80 office workers. Evaluation of subjects included a questionnaire on chronic respiratory symptoms, lung function tests, COPD diagnostics, and measurement of CRP serum concentrations...
October 15, 2017: Open Access Macedonian Journal of Medical Sciences
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