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Journal of Current Ophthalmology

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https://www.readbyqxmd.com/read/28367532/the-effect-of-anakinra-on-retinal-function-in-isolated-perfused-vertebrate-retina
#1
Mahdy Ranjbar, Toni Schneider, Carl Brand, Salvatore Grisanti, Julia Lüke, Matthias Lüke
PURPOSE: Blockage of the interleukin 1 (IL-1) signaling pathway has been proposed for treatment of inflammatory disorders like those affecting the retina and its adjacent tissue. Herein, we evaluated one of those inhibitory drugs, anakinra (Kineret(®)), based on its safety profile with emphasis on retinal function from an electrophysiological point of view. METHODS: Bovine retina preparations were perfused with two different concentrations of anakinra (1 mg/ml and 2 mg/ml)...
March 2017: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/28367531/bilateral-cytomegalovirus-retinitis-in-a-healthy-infant
#2
Seyedeh Maryam Hosseini, Mir-Naghi Moosavi, Naser Shoeibi, Mehdi Sakhaee, Hossein Ghavamsaeedi
PURPOSE: To report a case of bilateral cytomegalovirus (CMV) retinitis in an otherwise healthy infant. METHODS: A four-month-old, healthy, male infant was evaluated for visual inattention. RESULTS: This full-term infant with a normal birth weight and an uneventful gestational period was referred with symptoms of visual inattention, fever, and agitation one week prior to admission. Ocular involvements were detected in the form of bilateral pan uveitis with diffuse bilateral retinitis and vasculitis with hemorrhage in the peripheral retina and posterior pole...
March 2017: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/28367530/choroidal-neovascularization-following-photorefractive-keratectomy
#3
Hamidreza Torabi, Seyed-Hashem Daryabari
PURPOSE: To describe a case of choroidal neovascularization (CNV) following photorefractive keratectomy (PRK) to correct myopia. METHODS: We performed PRK in both eyes of a 20-year-old girl to correct myopia. Refractive error was -4.75 -2.25 × 5 in the right eye and -5.00 -1.25 × 180 in the left eye. Metamorphopsia was noticed by the patient in the right eye one month after the surgical procedure. The patient was referred 3 months later when visual loss happened...
March 2017: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/28367529/conjunctival-bacterial-flora-in-fellow-eyes-of-patients-with-unilateral-nasolacrimal-duct-obstruction-and-its-changes-after-successful-dacryocystorhinostomy-surgery
#4
Bahram Eshraghi, Sayyed Amirpooya Alemzadeh, Zohreh Abedinifar
PURPOSE: To evaluate the results of conjunctival culture in fellow eyes of patients with unilateral nasolacrimal duct obstruction (NLDO) and its changes after successful dacryocystorhinostomy (DCR) surgery. METHODS: In this prospective study, 71 adult patients with unilateral NLDO and 41 age and sex-matched controls without NLDO were evaluated. The patients were divided into 2 groups based on clinical examination; group A with purulent regurgitation and group B without purulent regurgitation...
March 2017: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/28367528/the-predictive-factors-of-diplopia-and-extraocular-movement-limitations-in-isolated-pure-blow-out-fracture
#5
Abolfazl Kasaee, Arash Mirmohammadsadeghi, Fatemeh Kazemnezhad, Bahram Eshraghi, Mohammad Reza Akbari
PURPOSE: To evaluate the predictive factors for development of diplopia and extraocular muscle movement (EOM) limitations in the patients with isolated pure blow-out fracture. METHODS: One hundred thirty-two patients with isolated pure blow-out fracture were included. The diagnosis was done with computed tomography scan. Possible predictive factors were analyzed with logistic regression. The cases that underwent surgery were assigned in the surgical group, and other cases were assigned in the non-surgical group...
March 2017: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/28367527/botulinum-toxin-injection-in-the-patients-with-duane-syndrome-type-1
#6
Ahmad Ameri, Farzad Farzbod, Fatemeh Bazvand, Arash Mirmohammadsadeghi, Mohammadreza Akbari, Faramarz Anvari, Simindokht Hosseini
PURPOSE: To evaluate the efficacy of botulinum toxin injection in the patients with type 1 Duane syndrome and identify the predictive factors for success. METHODS: Sixteen patients with esotropic type 1 Duane syndrome without history of ocular surgery were selected for this interventional case series. The botulinum toxin was injected in the medial rectus of all patients. Visual acuity, dry refraction, cyclo-refraction, ocular motility, and amount of deviation were measured...
March 2017: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/28367526/choroidal-thickness-in-idiopathic-macular-hole
#7
Reza Karkhaneh, Masoud Nikbakht, Fatemeh Bazvand, Afshin Kalantary Oskouei, Hamed Ghasemi, Fariba Ghassemi
PURPOSE: To measure the submacular choroidal thickness in eyes with idiopathic macular hole (IMH) compared with unaffected fellow eyes and normal control eyes. METHODS: In this single institutional retrospective comparative case-control study, 34 consecutive patients with IMH were included and compared with 30 normal age- and sex-matched eyes that were planned to have cataract surgery. The included eyes were divided into 4 groups: 41 eyes with IMH (A), 23 unaffected fellow eyes (B), 30 normal eyes (C), and 12 vitrectomized IMH eyes (D)...
March 2017: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/28367525/the-distribution-of-orbscan-indices-in-young-population
#8
Hassan Hashemi, Mehdi Khabazkhoob, Negareh Yazdani, Hadi Ostadimoghaddam, Payam Nabovati, Raheleh Moravej, AbbasAli Yekta
PURPOSE: To determine the distribution of anterior eye biometry indices, such as keratometry pachymetry, anterior chamber depth (ACD), pupil diameter, and corneal diameter, as measured by Orbscan instrument in a young Iranian population. METHODS: A cross-sectional study was conducted, and subjects were selected through multistage cluster sampling from the students of Mashhad University of Medical Sciences. Objective and subjective refraction were performed followed by Orbscan imaging...
March 2017: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/28367524/effects-of-adjuvant-omega-3-fatty-acid-supplementation-on-dry-eye-syndrome-following-cataract-surgery-a-randomized-clinical-trial
#9
Mehrdad Mohammadpour, Shima Mehrabi, Narges Hassanpoor, Reza Mirshahi
PURPOSE: To investigate the effect of omega-3 polyunsaturated fatty acid supplement on qualitative and quantitative subjective (ocular surface disease index [OSDI]) and objective (Schirmer's test, tear break up time [TBUT], and tear osmolarity) dry eye indices after cataract surgery. METHODS: In this randomized clinical study, 61 eyes of 48 patients complaining of new onset dry eye symptoms after phacoemulsification were enrolled. Subjects were randomly allocated into two groups using urn randomization...
March 2017: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/28367523/stromal-cell-derived-factor-1-cxcr4-and-cxcr7-gene-transcripts-in-pterygia
#10
Shahram Bamdad, Behzad Khademi, Nooshin Chenari, Atta Taseh, Mahboobeh Razmkhah
PURPOSE: Pterygium is a pathologic process with angiogenic and tumor cell like characteristics. Chemokine and chemokine receptors may contribute to the formation and growth of pterygia. The aim of this study was to assess the expression of stromal cell derived factor (SDF)-1, as an angiogenic chemokine, and its receptors, CXCR4 and CXCR7, gene transcripts in pterygia. METHODS: RNA was extracted from tissue samples of 33 patients with primary pterygium and 35 volunteers with conjunctiva as the control group...
March 2017: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/28367522/corneal-thickness-measurements-with-scheimpflug-and-slit%C3%A2-scanning%C3%A2-imaging-techniques-in-keratoconus
#11
Mohammad Aghazadeh Amiri, Hassan Hashemi, Shahroukh Ramin, Abbasali Yekta, Azadeh Taheri, Payam Nabovati, Mehdi Khabazkhoob
PURPOSE: To determine the repeatability of corneal thickness measurements with Scheimpflug (Pentacam) and slit scanning (Orbscan) imaging techniques in different grades of keratoconus. METHODS: This study was conducted as a cross-sectional research. Imaging with Orbscan and Pentacam was performed on patients with different grades of keratoconus. With each device, 3 measurements were taken at 10 min intervals. Repeatability indices in different grades of keratoconus were calculated for each device...
March 2017: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/28367521/combined-cataract-extraction-and-trabeculotomy-by-the-internal-approach-for-coexisting-cataract-and-open-angle-glaucoma
#12
Seyed Javad Hashemian, Arezoo Miraftabi, Mohammad Ebrahim Jafari, Mohsen Rezaei Hemami
PURPOSE: To provide efficacy and safety of surgery with Trabectome combined with phacoemulsification in primary open-angle glaucoma. METHODS: In this interventional case series, 30 consecutive eyes that have had combined phacoemulsification with Trabectome were included. The main outcome measures were change in intraocular pressure (IOP), glaucoma medication use, and the rate of complications. RESULTS: Mean IOP was 18.25 ± 3.28 mmHg preoperatively which decreased to 13...
March 2017: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/28367520/therapeutic-targets-of-renin-angiotensin-system-in-ocular-disorders
#13
REVIEW
Rajesh Choudhary, Mandeep Singh Kapoor, Amrita Singh, Surendra H Bodakhe
PURPOSE: To review current literature on the renin-angiotensin system (RAS)-mediated pathogenic mechanisms and therapeutic targets in ocular diseases. METHODS: A comprehensive literature survey was performed on PubMed, Scopus, and Google Scholar databases published from 1977 to 2016. The search terms were a RAS, angiotensin, angiotensin receptor, prorenin, pro (renin) receptor, angiotensin converting enzyme inhibitor, angiotensin receptor blocker associated with ocular disorders like cataract, glaucoma, diabetic retinopathy (DR), macular degeneration, and uveitis...
March 2017: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/28367519/this-issue-at-a-glance
#14
EDITORIAL
(no author information available yet)
No abstract text is available yet for this article.
March 2017: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/28367518/optical-coherence-tomography-angiography-of-the-retina-and-choroid-current-applications-and-future-directions
#15
EDITORIAL
Khalil Ghasemi Falavarjani, David Sarraf
No abstract text is available yet for this article.
March 2017: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/27830212/statistical-analysis-of-stereoacuity-in-ophthalmology-research
#16
Alireza Peyman, Mohammadreza Peyman
No abstract text is available yet for this article.
December 2016: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/27830211/clues-from-crouzon-insights-into-the-potential-role-of-growth-factors-in-the-pathogenesis-of-myelinated-retinal-nerve-fibers
#17
Giancarlo A Garcia, Jack J Tian, Supanut Apinyawasisuk, Sarah Kim, Handan Akil, Alfredo A Sadun
PURPOSE: We present a case of bilateral extensive peripapillary myelinated retinal nerve fibers (MRNF) in an individual with Crouzon syndrome, an inherited form of craniosynostosis caused by overactivation of fibroblast growth factor receptor 2. As a secondary aim, we examine the utility of optical coherence tomography (OCT) angiography for visualization of peripapillary vasculature obscured by myelination on other imaging modalities. METHODS: A 24-year-old woman with Crouzon syndrome was evaluated for suspected optic neuritis in the right eye...
December 2016: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/27830210/optic-nerve-glioma-with-complete-intraocular-extension
#18
Masoomeh Eghtedari, Seyede Fariba Fattahi, Naser Owji, Mohammad Javad Ashraf, Mohammad Reza Khalili, Bita Geramizadeh
PURPOSE: To present a rare presentation of optic nerve glioma (ONG) with total intraocular extension. METHODS: A 44-year-old man with a history of loss of vision since childhood and recent development of progressive disfiguring proptosis was referred. RESULTS: The vision in the affected eye was no light perception, and a proptosis of about 2-3 mm was present. Computed tomography and Magnetic Resonance Imaging (MRI) of brain/orbit showed a fusiform enlargement of the left optic nerve and total filling of vitreous cavity by a mass with high signal intensity in T2-weighted MRI...
December 2016: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/27830209/tear-deformation-time-and-optical-quality-in-eyes-wearing-silicone-hydrogel-contact-lenses
#19
Amir Asharlous, Ebrahim Jafarzadehpur, Ali Mirzajani, Mehdi Khabazkhoob, Samira Heydarian, Ali Taghipour
PURPOSE: To evaluate tear film stability and optical aberrations in eyes wearing plano Lotrafilcon B contact lenses (CL). METHODS: Tear Deformation Time (TDT) and aberrometric parameters were assessed in 86 normal emmetropic eyes before and 6 h after wearing CL. RESULT: A statistically significant decrease in TDT and increase in root mean square (RMS) values of higher order aberrations (HOA) were revealed 6 h after CL insertion (both P < 0...
December 2016: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/27830208/behavior-disorders-in-children-with-significant-refractive-errors
#20
Gholamhoseyn Aghai, Parvin Dibajnia, Esmat Ashkesh, Mohammadreza Nazari, Khalil Ghasemi Falavarjani
PURPOSE: To evaluate the frequency of behavioral disorders in children with significant refractive error and to compare the results with those of emmetropic children. METHODS: In this prospective, comparative study from January to September 2013, refractive errors of all 5-12-year-old children who referred to a general eye clinic were recorded. A validated Persian version of the Rutter A scale was filled out by the parents for the evaluation of the child's behavioral disorders...
December 2016: Journal of Current Ophthalmology
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