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Skin Appendage Disorders

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https://www.readbyqxmd.com/read/29177154/syphilitic-alopecia-case-reports-and-trichoscopic-findings
#1
Isabella Doche, Maria K Hordinsky, Neusa Y S Valente, Ricardo Romiti, Antonella Tosti
There has been a resurgence of syphilis in the last decade. Although alopecia is not a common manifestation of the disease, the "moth-eaten" pattern is considered patognomonic. However, diffuse hair loss, termed essential alopecia, sometimes can be the only sign of syphilis infection and mimic other conditions, such as alopecia areata and telogen effluvium. We describe three patients with syphilis in whom the pattern of alopecia was not typical. Although clinical, histopathological, and trichoscopic examinations may share some similar findings with other hair diseases, the inclusion of syphilis in the differential diagnosis of hair loss causes is fundamental to a correct screening and diagnosis...
October 2017: Skin Appendage Disorders
https://www.readbyqxmd.com/read/29177153/poliosis-and-neurofibromatosis-type-1-two-familiar-cases-and-review-of-the-literature
#2
Iria Neri, Giulia Liberati, Bianca Maria Piraccini, Annalisa Patrizi
Two brothers were referred to our clinic for reevaluation of neurofibromatosis type 1 (NF1). Both brothers presented a peculiarity that is not so common in NF1: poliosis overlying plexiform neurofibromas on the scalp. Poliosis overlying plexiform neurofibromas is rarely reported in the literature. The peculiarity of our cases is the familiarity and the presence of poliosis in the same location.
October 2017: Skin Appendage Disorders
https://www.readbyqxmd.com/read/29177152/an-atypical-localized-form-of-hidradenitis-suppurativa-of-the-jawline-and-neck-mimicking-severe-cystic-acne-on-presentation
#3
María Adriana Castrillón Velásquez, Minhee Kim, Mei-Heng Tan, Kim Tran, Dedee F Murrell
Hidradenitis suppurativa (HS) is a chronic and debilitating suppurative disease primarily affecting the axillae, perineum, and inframammary regions, where apocrine sweat glands are present. However, HS can occur in atypical locations. We present an interesting case of a 40-year-old man who developed chronic painful subcutaneous nodules, deep sinus tracts, and abscesses involving the jawline and the anterior aspect of the neck as the only parts of the body affected and who responded satisfactorily to adalimumab and laser hair removal treatment...
October 2017: Skin Appendage Disorders
https://www.readbyqxmd.com/read/29177151/blue-white-veil-as-novel-dermatoscopic-feature-in-discoid-lupus-erythematosus-in-2-african-american-patients
#4
Jessica Cervantes, Farhaan Hafeez, Mariya Miteva
Dermoscopic features of discoid lupus erythematosus (DLE) depend on the stage of the lesions: active lesions include yellow-brown dots and red dots, whereas longstanding inactive lesions show absence of follicular openings, cicatricial milky red or white patches, structureless white and brown areas, and thick arborizing vessels. Loss of pinpoint white dots, blue-gray dots in a speckled pattern, and a peripheral pigmented network have been described on dermoscopy of DLE in dark skin. We report a blue-white veil as a novel dermoscopic feature in 2 cases of biopsy-proven DLE in African-American patients...
October 2017: Skin Appendage Disorders
https://www.readbyqxmd.com/read/29177150/cutaneous-lupus-erythematosus-presenting-as-frontal-fibrosing-alopecia-report-of-2-patients
#5
Ralph M Trüeb, Laila El Shabrawi-Caelen, Werner Kempf
Frontal fibrosing alopecia represents a peculiar condition with a quasi-symmetrical, marginal scarring alopecia along the frontal and temporal hairline. The condition has been associated with further histopathologic and/or clinical evidence of lichen planopilaris. Since its emergence with the original report of Kossard in 1994, frontal fibrosing alopecia has been recognized to be associated with a number of comorbidities, including lupus erythematosus. So far, respective case reports and case series have given account of frontal fibrosing alopecia with the histopathologic features of lichen planopilaris associated or overlapping with lupus erythematosus...
October 2017: Skin Appendage Disorders
https://www.readbyqxmd.com/read/29177149/basal-cell-carcinoma-in-a-childhood-cancer-survivor-what-neurosurgeons-should-avoid
#6
Zoe Apalla, Eleni Sotiriou, Aimilios Lallas, Elizabeth Lazaridou, Efstratios Vakirlis, Demetrios Ioannides
Among childhood cancer survivors (CCSs), non-melanoma skin cancer (NMSC) is the most common type of second malignancy. Morbidity related to the development of NMSC in this group of patients may be sometimes unpredictable and difficult to manage. We present the case of a 49-year-old female who was a CCS and developed giant superficial basal cell carcinomas (sBCCs) over the previously irradiated field of the scalp. BCC involved the atrophic skin overlying the catheter of the peritoneal cerebral shunt that was set there for the management of hydrocephalus...
October 2017: Skin Appendage Disorders
https://www.readbyqxmd.com/read/29177148/descriptive-epidemiology-of-hidradenitis-suppurativa-in-greece-a-study-of-152-cases
#7
Alexandros C Katoulis, Aikaterini I Liakou, Nikolaos Rotsiamis, Stefanos Bonovas, Evangelia Bozi, Efstathios Rallis, Christos Christodoulou, Dimitrios Rigopoulos
Background/Objective: Hidradenitis suppurativa (HS) is a chronic, inflammatory skin disease that remarkably affects the patients' quality of life. A prospective study of 152 HS patients was conducted in order to depict the clinico-epidemiological characteristics of HS patients in Greece. Materials and Methods: From February 2015 to August 2016, 152 patients attended the Hidradenitis Suppurativa Outpatient Clinic of our department. The most important clinico-epidemiological data of the patients were registered...
October 2017: Skin Appendage Disorders
https://www.readbyqxmd.com/read/29177147/exogen-hairs-in-women-with-and-without-hair-loss
#8
Marcella Guarrera, Alfredo Rebora
Contrary to the classical view of the hair cycle, in which telogen is the resting phase that precedes the release of the hair shaft, another phase has been introduced, exogen. Exogen is the phase wherein the processes for the release of the hair shaft are initiated and successfully executed. Exogen ends when the shaft is liberated. Accordingly, human hairs would be preferably released not with telogen but with exogen roots. To better understand this somehow revolutionary point and what occurs in telogen effluvium (TE) and in androgenetic alopecia (AGA), we undertook a morphological study...
October 2017: Skin Appendage Disorders
https://www.readbyqxmd.com/read/29177146/patchy-frontal-fibrosing-alopecia-description-of-an-incomplete-clinical-presentation
#9
Leticia Arsie Contin, Yana Lya de Almeida Ledá, Kédima Caldeira Nassif, Maria Victoria Suárez Restrepo
We describe 6 incomplete cases of frontal fibrosing alopecia (FFA). All patients were postmenopausal women. Their average age was 60 years; 2 of the women were Caucasian, and the remaining 4 women were of a mixed ethnicity. The disease duration ranged from 3 to 17 years. The patients' lesions presented as irregular alopecic plaques in the frontal and/or temporal regions, with few signs of perifollicular inflammation, slow progression, and progressive loss of the vellus hair in the frontal area. Loss of the eyebrows, facial hyperpigmentation, and loss of the body hair were observed in 3 patients, 1 patient, and 2 patients, respectively...
October 2017: Skin Appendage Disorders
https://www.readbyqxmd.com/read/29177145/digital-lichen-striatus-two-case-reports-one-with-onychodystrophy
#10
Uwe Wollina
No abstract text is available yet for this article.
October 2017: Skin Appendage Disorders
https://www.readbyqxmd.com/read/29177144/habit-tic-deformity-of-bilateral-thumb-and-toenails-in-a-young-boy-an-unusual-occurrence
#11
Archana Singal
No abstract text is available yet for this article.
October 2017: Skin Appendage Disorders
https://www.readbyqxmd.com/read/29177143/congenital-curved-nail-of-the-fourth-toe-associated-with-oral-disorders
#12
Nilton Di Chiacchio, Leandro Noriega, Nilton Gioia Di Chiacchio, Jorge Ocampo-Garza, Emerson Henrique Padoveze
Congenital curved nail of the fourth toe represents an unusual deformity in which the nail of the fourth toe curves in a plantar direction. It is unknown why only this toe is affected; however, the initial descriptions suggest that this is a mesodermal defect. We describe a case of congenital curved nail of the fourth toe associated with bifid uvula. There are only 2 reports mentioning the association of this nail abnormality with cleft palate and/or lip. In our patient, there was an association with bifid uvula that is considered a minor form of palatine fissure...
October 2017: Skin Appendage Disorders
https://www.readbyqxmd.com/read/29177142/highly-resistant-acrodermatitis-continua-of-hallopeau-and-pustular-psoriasis
#13
John W Frew, Dedee F Murrell
No abstract text is available yet for this article.
October 2017: Skin Appendage Disorders
https://www.readbyqxmd.com/read/29177141/a-case-of-circumscribed-scalp-morphea-with-perineural-lymphocytes-on-pathology
#14
David Saceda-Corralo, Aron G Nusbaum, Paolo Romanelli, Mariya Miteva
Scalp morphea presents as a scarring alopecia in en coup du sabre pattern. We report an unusual presentation of a round hairless patch of morphea on the occipital scalp present for 15 years. The scalp lesion aligned with 2 other hyperpigmented lesions of biopsy-proven morphea in the lower back. Pathology of horizontal sections from the scalp lesion showed follicular dropout, thickening of the collagen bundles, and preserved eccrine and follicular structures. Marked lymphocytic perineural infiltrate, a reported clue to the diagnosis of scalp morphea, contributed to the diagnosis...
October 2017: Skin Appendage Disorders
https://www.readbyqxmd.com/read/29177140/trichoscopy-of-steroid-induced-atrophy
#15
Rodrigo Pirmez, Leonardo S Abraham, Bruna Duque-Estrada, Patrícia Damasco, Débora Cadore Farias, Yanna Kelly, Isabella Doche
Intralesional corticosteroid (IL-CS) injections have been used to treat a variety of dermatological and nondermatological diseases. Although an important therapeutic tool in dermatology, a number of local side effects, including skin atrophy, have been reported following IL-CS injections. We recently noticed that a subset of patients with steroid-induced atrophy presented with ivory-colored areas under trichoscopy. We performed a retrospective analysis of trichoscopic images and medical records from patients presenting ivory-colored areas associated with atrophic scalp lesions...
October 2017: Skin Appendage Disorders
https://www.readbyqxmd.com/read/28879195/a-review-of-the-use-of-biotin-for-hair-loss
#16
REVIEW
Deepa P Patel, Shane M Swink, Leslie Castelo-Soccio
BACKGROUND: Biotin has gained commercial popularity for its claimed benefits on healthy hair and nail growth. Despite its reputation, there is limited research to support the utility of biotin in healthy individuals. OBJECTIVE: To systematically review the literature on biotin efficacy in hair and nail growth. METHODS: We conducted a PubMed search of all case reports and randomized clinical trials (RCTs) using the following terms: (biotin and hair); (biotin and supplementation and hair); (biotin supplementation); (biotin and alopecia); (biotin and nails); (biotin and dermatology), and (biotin recommendations)...
August 2017: Skin Appendage Disorders
https://www.readbyqxmd.com/read/28879194/an-unusual-case-of-contact-dermatitis
#17
Olivia B Hughes, Andrea D Maderal, Antonella Tosti
We report a case of acute psoriasiform contact dermatitis of the forehead and scalp related to the use of a low-laser light cap. The patient had a positive patch test to dimethylol dihydroxyethyleneurea (DMDE), methylisothiazolinone, kathon CG, and cobalt. We believe that DMDE in the fabric of the cap was responsible for the allergic contact dermatitis in this case as the lesions resolved with cessation of cap use.
August 2017: Skin Appendage Disorders
https://www.readbyqxmd.com/read/28879193/minocycline-induced-blue-gray-discoloration
#18
EDITORIAL
Michelangelo La Placa, Salvatore Domenico Infusino, Riccardo Balestri, Colombina Vincenzi
No abstract text is available yet for this article.
August 2017: Skin Appendage Disorders
https://www.readbyqxmd.com/read/28879192/unsuccessful-treatment-of-alopecia-areata-with-simvastatin-ezetimibe-experience-in-12-patients
#19
Mabe Freitas Gouveia, Ralph M Trüeb
BACKGROUND/AIMS: Alopecia areata is a common immune-mediated hair condition with limited treatment options and success rates. There is evidence that statins, which are used for reducing atherogenesis and cardiovascular disease, have immunomodulatory activities and therefore may also be used for treatment of selected dermatologic conditions, including alopecia areata. Among treatments evaluated for alopecia areata, oral simvastatin/ezetimibe therapy is currently under the scrutiny of expert opinion...
August 2017: Skin Appendage Disorders
https://www.readbyqxmd.com/read/28879191/patient-reported-outcomes-in-onychomycosis-a-review-of-psychometrically-evaluated-instruments-in-assessing-treatment-effectiveness
#20
REVIEW
Jenny Wang, Lauren E Wiznia, Evan A Rieder
PURPOSE: Onychomycosis is the most common nail disorder and causes morbidity and impaired quality of life (QOL). Patient-reported outcomes (PRO) are patients' assessment of their health status or treatment response. PROs help assess what is most bothersome to patients to identify targets for intervention. We sought to review the PRO instruments currently used to assess QOL and treatment response in onychomycosis patients. PROCEDURES: A systematic review was performed by searching PubMed, Embase, CINAHL, and PsycINFO databases through December 31, 2016, to identify all English language literature on onychomycosis, PRO, and QOL...
August 2017: Skin Appendage Disorders
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