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International Journal of Reproductive Biomedicine (Yazd, Iran)

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https://www.readbyqxmd.com/read/27738663/fertility-sparing-surgery-in-gestational-trophoblastic-neoplasia-a-report-of-4-cases
#1
Malihe Hasanzadeh, Ftemeh Vahid Roodsari, Shahnaz Ahmadi, Masoumeh Gavedan Mehr, Tabari Azadeh
BACKGROUND: Gestational trophoblastic neoplasia (GTN) is a curable disease that involves the development of malignant tumor in the woman after a normal or molar pregnancy. The position of surgery in GTN is not properly specified and is changing due to new chemotherapy protocols. However, the role of surgery is highlighted in chemotherapy-resistant GTN. Other indications of surgery in trophoblastic diseases are drug toxicity and uterine perforation. Based on the fact that most women in certain age tend to preserve fertility, this study reported 4 cases of successful treatment after fertility sparing surgery...
September 2016: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/27738662/association-of-lipid-profile-with-bone-mineral-density-in-postmenopausal-women-in-yazd-province
#2
Akram Ghadiri-Anari, Zahra Mortezaii-Shoroki, Mozhgan Modarresi, Ali Dehghan
BACKGROUND: Low bone mass is a major health problem in postmenopausal women. There is no general agreement regarding relationship between serum level of lipids and bone mineral density. OBJECTIVE: This study was carried out to investigate the association between lipid profile and bone mineral density (BMD) in postmenopausal women in Yazd, Iran. MATERIALS AND METHODS: This cross-sectional study was performed on 170 women aged between 50 and 70 years old with menopause for at least one year from Yazd, Iran, between March 2013 to September 2013...
September 2016: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/27738661/factors-influencing-first-childbearing-timing-decisions-among-men-path-analysis
#3
Nourossadat Kariman, Maliheh Amerian, Padideh Jannati, Fatemeh Salmani
BACKGROUND: Factors that influence men's childbearing intentions have been relatively unexplored in the literature. OBJECTIVE: This study aimed to determine the influencing factors about the first childbearing timing decisions of men. MATERIALS AND METHODS: In this cross-sectional study, 300 men who were referred to private and governmental healthcare centers in Shahrood, Iran were randomly recruited from April to September 2014. Data were collected using a demographic questionnaire, the Quality of Life Questionnaire; ENRICH Marital Satisfaction Questionnaire, Synder's Hope Scale, and the Multidimensional Scale of Perceived Social Support...
September 2016: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/27738660/does-intrauterine-saline-infusion-by-intrauterine-insemination-iui-catheter-as-endometrial-injury-during-ivf-cycles-improve-pregnancy-outcomes-among-patients-with-recurrent-implantation-failure-an-rct
#4
Saghar Salehpour, Marzieh Zamaniyan, Nasrin Saharkhiz, Shahrzad Zadeh Modares, Sedighe Hosieni, Samira Seif, Narges Malih, Parinaz Rezapoor, Mohammad-Reza Sohrabi
BACKGROUND: Recurrent implantation failure is one of the most issues in IVF cycles. Some researchers found that beneficial effects of endometrial Scratching in women with recurrent implantation failure, while some authors demonstrated contrary results. OBJECTIVE: The present study aimed to investigate the effect of intrauterine. Saline infusion as a form of endometrial injury, during fresh in vitro fertilization-embryo transfer cycle, among patients with recurrent implantation failure...
September 2016: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/27738659/imatinib-alters-cell-viability-but-not-growth-factors-levels-in-tm4-sertoli-cells
#5
Seyyed Mohammad Reza Hashemnia, Somayeh Atari-Hajipirloo, Shiva Roshan-Milani, Nasim Valizadeh, Sonya Mahabadi, Fatemeh Kheradmand
BACKGROUND: The anticancer agent imatinib (IM) is a small molecular analog of ATP that inhibits tyrosine kinase activity of platelet derived growth factors (PDGFs) and stem cell factor (SCF) receptor in cancer cells. However these factors have a key role in regulating growth and development of normal Sertoli, Leydig and germ cells. OBJECTIVE: The aim of this study was to determine cell viability, PDGF and SCF levels in mouse normal Sertoli cells exposed to IM. MATERIALS AND METHODS: In this experimental study, the mouse TM4 Sertoli cells were treated with 0, 2...
September 2016: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/27738658/xeno-free-culture-condition-for-human-bone-marrow-and-umbilical-cord-matrix-derived-mesenchymal-stem-stromal-cells-using-human-umbilical-cord-blood-serum
#6
Azadeh Esmaeli, Mojgan Moshrefi, Ali Shamsara, Seyed Hasan Eftekhar-Vaghefi, Seyed Noureddin Nematollahi-Mahani
BACKGROUND: Fetal bovine serum (FBS) is widely used in cell culture laboratories, risk of zoonotic infections and allergic side effects create obstacles for its use in clinical trials. Therefore, an alternative supplement with proper inherent growth-promoting activities is demanded. OBJECTIVE: To find FBS substitute, we tested human umbilical cord blood serum (hUCS) for proliferation of human umbilical cord matrix derived mesenchymal stem cells (hUC-MSCs) and human bone marrow-derived mesenchymal cells (hBM-MSCs)...
September 2016: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/27738657/gnrh-agonist-trigger-versus-hcg-trigger-in-gnrh-antagonist-in-ivf-icsi-cycles-a-review-article
#7
Ashraf Alyasin, Shayesteh Mehdinejadiani, Marzieh Ghasemi
Routinely, a bolus of 5.000-10.000 IU human chorionic gonadotropin (hCG) is used for the final follicular maturation and ovulation as a standard method. HCG has the same effect of luteinizing hormone (LH) with long half-life. It has the long lutheotrophic effect which increases the risk of ovarian hyper stimulation syndrome (OHSS). Recently, gonadotropin-releasing hormone agonist (GnRH-a) trigger has been used for the induction of final follicular maturation and ovulation with the aim of reducing the OHSS risk...
September 2016: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/27679830/kallmann-syndrome-and-deafness-an-uncommon-combination-a-case-report-and-a-literature-review
#8
Nader Salama
BACKGROUND: Kallmann syndrome (Kal S) is an isolated form of hypogonadotrophic hypogonadism in combination with a defect in smell sensation. Depending on the genetic form of the disease, a number of non-reproductive, non-olfactory abnormalities may also be existent. In the present report, we describe a male with Kal S associated with hearing loss, and the successful treatment of his sexual and reproductive defects. CASE: A 23-year-old Caucasian man presented with a lifelong lack of erection and ejaculation...
August 2016: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/27679829/the-influence-of-ginger-zingiber-officinale-on-human-sperm-quality-and-dna-fragmentation-a-double-blind-randomized-clinical-trial
#9
Jalil Hosseini, Azar Mardi Mamaghani, Hani Hosseinifar, Mohammad Ali Sadighi Gilani, Farid Dadkhah, Mahdi Sepidarkish
BACKGROUND: Although the effectiveness of ginger as an antioxidant agent has been exploited, little human research has been conducted on its activity on male reproductive functions. OBJECTIVE: This study was designed to investigate the effects of ginger (Zingiber officinale) on sperm DNA fragmentation (SDF) in infertile men. MATERIALS AND METHODS: This randomized double-blind, placebo-controlled trial with a 1:1 allocation was performed on 100 infertility treatment candidates who were admitted to Royan Institute for Reproductive Biomedicine, Tehran, Iran...
August 2016: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/27679828/mutation-analysis-of-exon1-of-bone-morphogenetic-protein-15-gene-in-iranian-patients-with-polycystic-ovarian-syndrome
#10
Anahita Mehdizadeh, Mohammad Hasan Sheikhha, Seyed Mehdi Kalantar, Bibi Shahnaz Aali, Azam Ghanei
BACKGROUND: With the prevalence of 6-10%, polycystic ovarian syndrome (PCOS) is considered the most common endocrinological disorder affecting women in their reproductive age. It has been suggested that genetic factors participate in the development of PCOS. Follicular development has been considered as one of the impaired processes in PCOS. Bone morphogenetic protein-15 (BMP-15) gene is a candidate gene in follicular development and its variants may play role in pathogenesis of PCOS...
August 2016: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/27679827/antioxidant-and-protective-effects-of-royal-jelly-on-histopathological-changes-in-testis-of-diabetic-rats
#11
Elham Ghanbari, Vahid Nejati, Mozafar Khazaei
BACKGROUND: Diabetes is the most common endocrine disease. It has adverse effects on male reproductive function. Royal Jelly (RJ) has antioxidant and anti-diabetic effects and show protective effects against diabetes. OBJECTIVE: This study was conducted to evaluate the effect of RJ on histopathological alterations of the testicular tissue in streptozotocin (STZ)-induced diabetic rats. MATERIALS AND METHODS: In this experimental study, 28 adult Wistar rats were randomly divided into control (C), royal jelly (R), diabetic (D) and RJ-treated diabetic (D+R) groups...
August 2016: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/27679826/alternation-of-apoptotic-and-implanting-genes-expression-of-mouse-embryos-after-re-vitrification
#12
Nasrin Majidi Gharenaz, Mansoureh Movahedin, Zohreh Mazaheri, Shahram Pour Beiranvand
BACKGROUND: Nowadays, oocytes and embryos vitrification has become a routine technique. Based on clinical judgment, re-vitrification maybe required. But little is known about re-vitrification impact on genes expression. OBJECTIVE: The impact of re-vitrification on apoptotic and implanting genes, Bax, Bcl-2 and ErbB4, at compaction stage embryos were evaluated in this study. MATERIALS AND METHODS: In this experimental study, 8 cell embryos (n=240) were collected from female mature mice, 60-62 hr post HCG injection...
August 2016: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/27679825/the-effect-of-luteal-phase-gonadotropin-releasing-hormone-antagonist-administration-on-ivf-outcomes-in-women-at-risk-of-ohss
#13
Maryam Eftekhar, Sepideh Miraj, Zahrasadat Mortazavifar
BACKGROUND: Gonadotropin-releasing hormone (GnRH) plays essential roles in embryo implantation, invasion of trophoblastic tissue, and steroid synthesis in the placenta. OBJECTIVE: The aim of this study was to evaluate the effect of GnRH antagonist administration on pregnancy outcomes in early implantation period. MATERIALS AND METHODS: In this retrospective study, 94 infertile women undergoing GnRH antagonist protocol who were at risk of ovarian hyperstimulation syndrome (OHSS) were included...
August 2016: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/27679824/analysis-of-ovarian-reserve-markers-amh-fsh-afc-in-different-age-strata-in-ivf-icsi-patients
#14
Ensieh Shahrokh Tehraninezhad, Fatemeh Mehrabi, Raheleh Taati, Vahid Kalantar, Elham Aziminekoo, Azam Tarafdari
BACKGROUND: The predictive roles of follicle stimulating hormone (FSH), anti-mullerian hormone (AMH) and antral follicle count (AFC) as ovarian reserve markers in women with different age groups are not established well. OBJECTIVE: This study compares the value of FSH, AMH and AFC at the time of in vitro fertilization (IVF) treatment in different age groups. MATERIALS AND METHODS: In this cross-sectional study, 103 women aged 20-43 years candidates for IVF/ICSI cycle were recruited...
August 2016: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/27679823/pcos-women-show-significantly-higher-homocysteine-level-independent-to-glucose-and-e2-level
#15
Zahra Eskandari, Rajab-Ali Sadrkhanlou, Vahid Nejati, Gholamreza Tizro
BACKGROUND: It is reasonable to think that some biochemical characteristics of follicular fluid (FF) surrounding the oocyte may play a critical role in determining the quality of oocyte and the subsequent potential needed to achieve fertilization and embryo development. OBJECTIVE: This study was carried out to evaluate the levels of FF homocysteine (Hcy) in IVF candidate polycystic ovary syndrome (PCOS) women and any relationships with FF glucose and estradiol (E2) levels...
August 2016: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/27525334/spontaneous-uterine-rupture-after-abdominal-myomectomy-at-the-gestational-age-of-20-weeks-in-pregnancy-a-case-report
#16
Hamideh Pakniat, Nasrin Soofizadeh, Marzieh Beigom Khezri
BACKGROUND: Uterine rupture in pregnancy is rare and often could be life threatening and catastrophic. Myomectomy is one of very common surgeries in gynecology, performed as the vaginal, abdominal and laparoscopic surgeries. Pregnancies occured after abdominal and laparoscopic myomectomy are high risk for uterine rapture. CASE: Patient was a 28 Years old female, pregnant woman at the 20 wks of gestational age with abdominal pain and a history of abdominal myomectomy 6 yrs ago...
July 2016: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/27525333/association-between-hla-e-gene-polymorphism-and-unexplained-recurrent-spontaneous-abortion-rsa-in-iranian-women
#17
Maryam Fotoohi, Nasrin Ghasemi, Seyed Ali Mirghanizadeh, Mahmood Vakili, Morteza Samadi
BACKGROUND: Human leukocyte antigen-E (HLA-E)is a non-classical major histocompatibility complex (MHC) class I antigens which expressed on extra villous cytotrophoblast, which interacts with NKG2A, is an inhibitory receptor on natural killer (NK) cells and leading to down regulation of immune response in the maternal-fetal interface and provides maternal immune tolerance of the fetus. OBJECTIVE: This study was designated to investigate the gene frequencies of E0101 and E0103 in HLA-E gene in Iranian women with recurrent spontaneous abortion (RSA)...
July 2016: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/27525332/the-effect-of-steroid-hormones-on-the-mrna-expression-of-oct4-and-sox2-in-uterine-tissue-of-the-ovariectomized-mice-model-of-menopause
#18
Marzieh Davoudi, Saeed Zavareh, Mohammad Taghi Ghorbanian, Seyed Hassan Paylakhi, Seyed Reza Mohebbi
BACKGROUND: The uterus is a dynamic tissue responding to hormonal changes during reproductive cycles. As such, uterine stem cells have been studied in recent years. Transcription factors oct4 and sox2 are critical for effective maintenance of pluripotent cell identity. OBJECTIVE: The present research evaluated the mRNA expression of oct4 and sox2 in the uterine tissues of ovariectomized mice treated with steroid hormones. MATERIALS AND METHODS: In this experimental study, adult virgin female mice were ovariectomized and treated with estradiol 17β (E2), progesterone (P4), and a combination of E2 and P4 (E2 & P4) for 5 days...
July 2016: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/27525331/modified-natural-cycle-frozen-thawed-embryo-transfer-in-patients-with-repeated-implantation-failure-an-observational-study
#19
Soheila Arefi, Ahmad Hoseini, Fattaneh Farifteh, Hojjat Zeraati
BACKGROUND: Natural endometrium in Frozen-thawed Embryo Transfer (FET) may have some benefits upon implantation in patients with Repeated Implantation Failure (RIF). It might be due to possible differences between natural and stimulated endometrial growth factors and cytokins secretions. OBJECTIVE: The objective of this study was to compare the pregnancy rate of FET on modified natural cycle versus hormone replacement therapy (HRT) cycle endometrium in patients with RIF...
July 2016: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/27525330/frequency-of-null-allele-of-human-leukocyte-antigen-g-hla-g-locus-in-subjects-to-recurrent-miscarriage
#20
Nazila Alizadeh, Elnaz Mosaferi, Laya Farzadi, Jafar Majidi, Amir Monfaredan, Bahman Yousefi, Behzad Baradaran
BACKGROUND: Human leukocyte antigen-G (HLA-G) is a non-classical class I molecule highly expressed by extravillous cytotrophoblast cells. Due to a single base pair deletion, its function can be compensated by other isoforms. Investigating the frequency of null allele in Recurrent Miscarriage (RM) subjects could be useful in understanding the relationship between frequency of this allele and RM in a given population. OBJECTIVE: This study aimed to determine the frequency of HLA-G*0105N null allele and its potential association with down-regulation of HLA-G in subjects with RM...
July 2016: International Journal of Reproductive Biomedicine (Yazd, Iran)
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