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Nature Reviews. Disease Primers

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https://www.readbyqxmd.com/read/30002421/vibrio-spp-infections
#1
REVIEW
Craig Baker-Austin, James D Oliver, Munirul Alam, Afsar Ali, Matthew K Waldor, Firdausi Qadri, Jaime Martinez-Urtaza
Vibrio is a genus of ubiquitous bacteria found in a wide variety of aquatic and marine habitats; of the >100 described Vibrio spp., ~12 cause infections in humans. Vibrio cholerae can cause cholera, a severe diarrhoeal disease that can be quickly fatal if untreated and is typically transmitted via contaminated water and person-to-person contact. Non-cholera Vibrio spp. (for example, Vibrio parahaemolyticus, Vibrio alginolyticus and Vibrio vulnificus) cause vibriosis - infections normally acquired through exposure to sea water or through consumption of raw or undercooked contaminated seafood...
July 12, 2018: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/30002373/vibrio-spp-infections
#2
(no author information available yet)
No abstract text is available yet for this article.
July 12, 2018: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/29977059/ewing-sarcoma
#3
REVIEW
Thomas G P Grünewald, Florencia Cidre-Aranaz, Didier Surdez, Eleni M Tomazou, Enrique de Álava, Heinrich Kovar, Poul H Sorensen, Olivier Delattre, Uta Dirksen
Ewing sarcoma is the second most frequent bone tumour of childhood and adolescence that can also arise in soft tissue. Ewing sarcoma is a highly aggressive cancer, with a survival of 70-80% for patients with standard-risk and localized disease and ~30% for those with metastatic disease. Treatment comprises local surgery, radiotherapy and polychemotherapy, which are associated with acute and chronic adverse effects that may compromise quality of life in survivors. Histologically, Ewing sarcomas are composed of small round cells expressing high levels of CD99...
July 5, 2018: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/29976985/ewing-sarcoma
#4
(no author information available yet)
No abstract text is available yet for this article.
July 5, 2018: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/29955068/influenza
#5
REVIEW
Florian Krammer, Gavin J D Smith, Ron A M Fouchier, Malik Peiris, Katherine Kedzierska, Peter C Doherty, Peter Palese, Megan L Shaw, John Treanor, Robert G Webster, Adolfo García-Sastre
No abstract text is available yet for this article.
June 28, 2018: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/29955060/influenza
#6
(no author information available yet)
No abstract text is available yet for this article.
June 28, 2018: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/29930279/atopic-dermatitis
#7
Lucia Brunello
No abstract text is available yet for this article.
June 21, 2018: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/29930242/atopic-dermatitis
#8
REVIEW
Stephan Weidinger, Lisa A Beck, Thomas Bieber, Kenji Kabashima, Alan D Irvine
Atopic dermatitis (AD) is the most common chronic inflammatory skin disease, with a lifetime prevalence of up to 20% and substantial effects on quality of life. AD is characterized by intense itch, recurrent eczematous lesions and a fluctuating course. AD has a strong heritability component and is closely related to and commonly co-occurs with other atopic diseases (such as asthma and allergic rhinitis). Several pathophysiological mechanisms contribute to AD aetiology and clinical manifestations. Impairment of epidermal barrier function, for example, owing to deficiency in the structural protein filaggrin, can promote inflammation and T cell infiltration...
June 21, 2018: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/29877317/hepatitis-b-virus-infection
#9
REVIEW
(no author information available yet)
No abstract text is available yet for this article.
June 7, 2018: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/29877316/hepatitis-b-virus-infection
#10
REVIEW
Man-Fung Yuen, Ding-Shinn Chen, Geoffrey M Dusheiko, Harry L A Janssen, Daryl T Y Lau, Stephen A Locarnini, Marion G Peters, Ching-Lung Lai
Hepatitis B virus (HBV) is a hepatotropic virus that can establish a persistent and chronic infection in humans through immune anergy. Currently, 3.5% of the global population is chronically infected with HBV, although the incidence of HBV infections is decreasing owing to vaccination and, to a lesser extent, the use of antiviral therapy to reduce the viral load of chronically infected individuals. The course of chronic HBV infection typically comprises different clinical phases, each of which potentially lasts for decades...
June 7, 2018: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/29849126/methicillin-resistant-staphylococcus-aureus
#11
REVIEW
(no author information available yet)
No abstract text is available yet for this article.
May 31, 2018: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/29849094/methicillin-resistant-staphylococcus-aureus
#12
REVIEW
Andie S Lee, Hermínia de Lencastre, Javier Garau, Jan Kluytmans, Surbhi Malhotra-Kumar, Andreas Peschel, Stephan Harbarth
Since the 1960s, methicillin-resistant Staphylococcus aureus (MRSA) has emerged, disseminated globally and become a leading cause of bacterial infections in both health-care and community settings. However, there is marked geographical variation in MRSA burden owing to several factors, including differences in local infection control practices and pathogen-specific characteristics of the circulating clones. Different MRSA clones have resulted from the independent acquisition of staphylococcal cassette chromosome mec (SCCmec), which contains genes encoding proteins that render the bacterium resistant to most β-lactam antibiotics (such as methicillin), by several S...
May 31, 2018: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/29795363/borderline-personality-disorder
#13
REVIEW
John G Gunderson, Sabine C Herpertz, Andrew E Skodol, Svenn Torgersen, Mary C Zanarini
Caretakers are often intimidated or alienated by patients with borderline personality disorder (BPD), compounding the clinical challenges posed by the severe morbidity, high social costs and substantial prevalence of this disorder in many health-care settings. BPD is found in ∼1.7% of the general population but in 15-28% of patients in psychiatric clinics or hospitals and in a large proportion of individuals seeking help for psychological problems in general health facilities. BPD is characterized by extreme sensitivity to perceived interpersonal slights, an unstable sense of self, intense and volatile emotionality and impulsive behaviours that are often self-destructive...
May 24, 2018: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/29795174/borderline-personality-disorder
#14
REVIEW
(no author information available yet)
No abstract text is available yet for this article.
May 24, 2018: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/29770793/pulmonary-embolism
#15
REVIEW
Menno V Huisman, Stefano Barco, Suzanne C Cannegieter, Gregoire Le Gal, Stavros V Konstantinides, Pieter H Reitsma, Marc Rodger, Anton Vonk Noordegraaf, Frederikus A Klok
Pulmonary embolism (PE) is caused by emboli, which have originated from venous thrombi, travelling to and occluding the arteries of the lung. PE is the most dangerous form of venous thromboembolism, and undiagnosed or untreated PE can be fatal. Acute PE is associated with right ventricular dysfunction, which can lead to arrhythmia, haemodynamic collapse and shock. Furthermore, individuals who survive PE can develop post-PE syndrome, which is characterized by chronic thrombotic remains in the pulmonary arteries, persistent right ventricular dysfunction, decreased quality of life and/or chronic functional limitations...
May 17, 2018: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/29770792/pulmonary-embolism
#16
REVIEW
(no author information available yet)
No abstract text is available yet for this article.
May 17, 2018: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/29749393/correction-paraneoplastic-autoimmune-multiorgan-syndrome-and-paraneoplastic-pemphigus-describe-the-same-spectrum-of-disease-pathology
#17
Aimee S Payne, Michael Kasperkiewicz, Christoph T Ellebrecht, Hayato Takahashi, Jun Yamagami, Detlef Zillikens, Masayuki Amagai
This corrects the article DOI: 10.1038/nrdp.2018.13.
May 11, 2018: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/29749387/invasive-candidiasis
#18
REVIEW
Peter G Pappas, Michail S Lionakis, Maiken Cavling Arendrup, Luis Ostrosky-Zeichner, Bart Jan Kullberg
Invasive candidiasis is an important health-care-associated fungal infection that can be caused by several Candida spp.; the most common species is Candida albicans, but the prevalence of these organisms varies considerably depending on geographical location. The spectrum of disease of invasive candidiasis ranges from minimally symptomatic candidaemia to fulminant sepsis with an associated mortality exceeding 70%. Candida spp. are common commensal organisms in the skin and gut microbiota, and disruptions in the cutaneous and gastrointestinal barriers (for example, owing to gastrointestinal perforation) promote invasive disease...
May 11, 2018: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/29749385/invasive-candidiasis
#19
REVIEW
(no author information available yet)
No abstract text is available yet for this article.
May 11, 2018: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/29722353/epilepsy
#20
REVIEW
(no author information available yet)
No abstract text is available yet for this article.
May 3, 2018: Nature Reviews. Disease Primers
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