Anna V Dowling, Benjamin A Seitzman, Timothy J Mitchell, Michael Olufawo, Donna L Dierker, Hari Anandarajah, Ally Dworetsky, Alana McMichael, Catherine Jiang, Dennis L Barbour, Bradley L Schlaggar, David D Limbrick, Jennifer M Strahle, Joshua B Rubin, Joshua S Shimony, Stephanie M Perkins
PURPOSE: Pediatric brain tumor patients often experience significant cognitive sequelae. Resting-state functional MRI (rsfMRI) provides a measure of brain network organization, and we hypothesize that pediatric brain tumor patients treated with proton therapy will demonstrate abnormal brain network architecture related to cognitive outcome and radiation dosimetry. PARTICIPANTS AND METHODS: Pediatric brain tumor patients treated with proton therapy were enrolled on a prospective study of cognitive assessment using the NIH Toolbox Cognitive Domain...
2023: International Journal of Particle Therapy