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European Heart Journal. Quality of Care & Clinical Outcomes

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https://www.readbyqxmd.com/read/29726987/admission-macrophage-migration-inhibitory-factor-predicts-long-term-prognosis-in-patients-with-st-elevation-myocardial-infarction
#1
Xiang-Ning Deng, Xin-Yu Wang, Hai-Yi Yu, Shao-Min Chen, Xin-Ye Xu, Wei Huai, Gui-Hua Liu, Qing-Bian Ma, You-Yi Zhang, Anthony M Dart, Xiao-Jun Du, Wei Gao
Background: We previously showed in patients with ST-segment elevated myocardial infarction (STEMI) that admission levels of macrophage migration inhibitory factor (MIF) predict infarct size. It remains unclear whether admission MIF alone or in combination with other biomarkers is useful for risk assessment of acute and chronic clinical outcomes in STEMI patients. Methods and Results: 566 STEMI patients treated with primary percutaneous coronary intervention (PCI) were consecutively recruited...
May 2, 2018: European Heart Journal. Quality of Care & Clinical Outcomes
https://www.readbyqxmd.com/read/29726982/a-real-world-cohort-study-on-the-quality-of-potassium-and-creatinine-monitoring-during-initiation-of-mineralocorticoid-receptor-antagonists-in-patients-with-heart-failure
#2
Erik Nilsson, Pietro De Deco, Marco Trevisan, Rino Bellocco, Bengt Lindholm, Lars H Lund, Josef Coresh, Juan J Carrero
AIMS: Clinical heart failure (HF) guidelines recommend monitoring of creatinine and potassium throughout the initial weeks of mineralocorticoid receptor antagonists (MRAs) therapy. We here assessed the extent to which this occurs in our healthcare. METHODS AND RESULTS: Observational study in 2007-2010 HF patients starting MRA therapy in Stockholm, Sweden. Outcomes included potassium and creatinine laboratory testing before MRA initiation and in the early (days 1-10) and extended (days 11-90) post-initiation periods...
May 2, 2018: European Heart Journal. Quality of Care & Clinical Outcomes
https://www.readbyqxmd.com/read/29718210/long-term-trends-of-use-of-health-service-among-heart-failure-patients
#3
Ahsan Rao, Dani Kim, Ara Darzi, Azeem Majeed, Paul Aylin, Alex Bottle
Aims: We aimed to identify subgroups in the patient population with different trajectories of long-term readmission rates. The study also aimed to assess common causes and their sequences of readmissions for each subgroup. Methods: Patients with a primary diagnosis of heart failure (HF) in the period 2008-2009 were identified using nationally representative primary care data linked to national hospital data, which contain information on 10.5 million patients. HF patients were followed up for 5 years...
April 28, 2018: European Heart Journal. Quality of Care & Clinical Outcomes
https://www.readbyqxmd.com/read/29701805/cardiac-rehabilitation-fitness-changes-and-subsequent-survival
#4
Alban De Schutter, Sergey Kachur, Carl J Lavie, Arthur Menezes, Kelly K Shum, Sripal Bangalore, Ross Arena, Richard V Milani
Aims: Assessments of cardiac rehabilitation (CR) in coronary heart disease (CHD) cohorts usually examine mortality in aggregate. The current study examines the prognosis and characteristics of patients who enrolled and completed CR, stratified by their level of improvement in cardiorespiratory fitness (CRF) by examining the characteristics, outcomes and predictors of non-response in CRF (NonRes) compared to low-responders (LowRes) and high-Responders (HighRes) after CR. Methods And Results: 1171 CHD patients were referred for a phase II CR program after therapy for an acute coronary syndrome, coronary artery bypass graft procedure or a percutaneous coronary intervention between January 1, 2000 and June 30, 2013 underwent cardiopulmonary exercise testing before and after CR...
April 26, 2018: European Heart Journal. Quality of Care & Clinical Outcomes
https://www.readbyqxmd.com/read/29688315/editorial-impact-of-cardiac-rehabilitation-on-cardiac-mortality
#5
Rod Taylor, Hasnain Dalal
No abstract text is available yet for this article.
April 24, 2018: European Heart Journal. Quality of Care & Clinical Outcomes
https://www.readbyqxmd.com/read/29617967/older-drugs-with-infantile-evidence-the-illustrative-example-of-loop-diuretics
#6
Behnood Bikdeli, Jeffrey M Testani, Joseph S Ross, Harlan M Krumholz
No abstract text is available yet for this article.
March 29, 2018: European Heart Journal. Quality of Care & Clinical Outcomes
https://www.readbyqxmd.com/read/29596567/malignant-disease-as-a-comorbidity-in-patients-with-severe-aortic-stenosis-clinical-presentation-outcomes-and-management
#7
Eri Minamino-Muta, Takao Kato, Takeshi Morimoto, Tomohiko Taniguchi, Kenji Nakatsuma, Yuki Kimura, Moriaki Inoko, Shinichi Shirai, Norio Kanamori, Koichiro Murata, Takeshi Kitai, Yuichi Kawase, Makoto Miyake, Chisato Izumi, Hirokazu Mitsuoka, Yutaka Hirano, Tomoki Sasa, Kazuya Nagao, Tsukasa Inada, Ryusuke Nishikawa, Yasuyo Takeuchi, Shintaro Yamagami, Keiichiro Yamane, Kanae Su, Akihiro Komasa, Katsuhisa Ishii, Yugo Yamashita, Yoshihiro Kato, Kensuke Takabayashi, Naritatsu Saito, Kenji Minatoya, Takeshi Kimura
Aim: To investigate the effect of malignancy on the outcomes of patients with severe aortic stenosis (AS) and the management strategy for AS with malignancy. Methods: Using data of 3815 patients with severe AS in a retrospective multicenter registry (CURRENT AS registry), we compared 3-year clinical outcomes among three groups based on malignancy status: with malignancy currently under treatment including best supportive care (malignancy group), with a history of malignancy without any current treatment (past history group), or without history of malignancy (no malignancy group)...
March 27, 2018: European Heart Journal. Quality of Care & Clinical Outcomes
https://www.readbyqxmd.com/read/29554233/normal-coronary-angiography-blessing-or-curse
#8
Rosanna Tavella, John F Beltrame
No abstract text is available yet for this article.
April 1, 2018: European Heart Journal. Quality of Care & Clinical Outcomes
https://www.readbyqxmd.com/read/29506022/movement-is-medicine-the-scandinavian-way
#9
David R Warriner, John Mandrola
No abstract text is available yet for this article.
April 1, 2018: European Heart Journal. Quality of Care & Clinical Outcomes
https://www.readbyqxmd.com/read/29390055/survival-and-incidence-of-cardiovascular-diseases-in-participants-in-a-long-distance-ski-race-vasaloppet-sweden-compared-with-the-background-population
#10
Ulf Hållmarker, Johan Lindbäck, Karl Michaëlsson, Johan Ärnlöv, Signild Åsberg, Per Wester, Dan Hellberg, Bo Lagerqvist, Stefan James
Aims: We studied the relationship between taking part in a long-distance ski race and incidence of cardiovascular diseases (CVDs) to address the hypothesis that lifestyle lowers the incidence. Methods and results: A cohort of 399 630 subjects in Sweden, half were skiers in the world's largest ski race, and half were non-skiers. Non-skiers were frequency matched for sex, age, and year of race. Individuals with severe diseases were excluded. The endpoints were death, myocardial infarction, or stroke...
April 1, 2018: European Heart Journal. Quality of Care & Clinical Outcomes
https://www.readbyqxmd.com/read/29390053/thromboembolisms-related-to-post-operative-electrical-cardioversions-for-atrial-fibrillation-in-patients-with-surgical-aortic-valve-replacement
#11
Tuomas Kiviniemi, Markus Malmberg, Fausto Biancari, Juha Hartikainen, Leo Ihlberg, Fredrik Yannopoulos, Teemu Riekkinen, Otto von Hellens, Joonas Lehto, Maunu Nissinen, Ke Juhani Airaksinen, Tuomo Nieminen
Aims: Post-operative atrial fibrillation (POAF) is a frequent complication after open-heart surgery, and cardioversions (CV) are commonly performed to restore sinus rhythm. However, little data exists on thrombo-embolic risk related to early post-operative CV and on the recurrence of POAF after CV. CAREAVR study sought to assess the rate of strokes, transient ischaemic attacks (TIA), and mortality shortly after POAF-triggered CV in patients who underwent isolated surgical aortic valve replacement (SAVR) with a bioprosthesis...
April 1, 2018: European Heart Journal. Quality of Care & Clinical Outcomes
https://www.readbyqxmd.com/read/29385436/do-patient-reported-outcome-measures-speak-for-all-patient-subgroups-is-everyone-included
#12
Krishnaraj S Rathod, Andrew Wragg
No abstract text is available yet for this article.
April 1, 2018: European Heart Journal. Quality of Care & Clinical Outcomes
https://www.readbyqxmd.com/read/29325012/systematic-review-of-the-cost-effectiveness-of-transcatheter-interventions-for-valvular-heart-disease
#13
Fotini Gialama, Panagiotis Prezerakos, Vasilis Apostolopoulos, Nikolaos Maniadakis
Transcatheter aortic valve implantation (TAVI) and transcatheter mitral valve repair (TMVR) are increasingly used for managing patients with valvular heart disease to whom surgery presents a high-risk. As these are costly procedures, a systematic review of studies concerned with their economic assessment was undertaken. The search was performed in PubMed and the Cochrane Library and followed recommended methodological steps. Studies were screened and their data were retrieved and were synthesized using a narrative approach...
April 1, 2018: European Heart Journal. Quality of Care & Clinical Outcomes
https://www.readbyqxmd.com/read/29309548/hospitalized-elderly-patients-for-acute-pericarditis-deserve-more-clinical-attention-and-a-closer-follow-up-monitoring
#14
Lovely Chhabra, David H Spodick
No abstract text is available yet for this article.
April 1, 2018: European Heart Journal. Quality of Care & Clinical Outcomes
https://www.readbyqxmd.com/read/29121222/neurological-effects-of-proprotein-convertase-subtilisin-kexin-type-9-inhibitors-direct-comparisons
#15
Navkaranbir S Bajaj, Nirav Patel, Rajat Kalra, Amier Ahmad, Anand Venkatraman, Garima Arora, Pankaj Arora
Aims: Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors considerably alter the lipid profile. We sought to examine the rates of ischaemic stroke and neurocognitive deficits in patients treated with and without PCSK9 inhibitors. Methods and results: Randomized controlled trials (RCTs) reporting rates of ischaemic stroke and neurocognitive deficits in patients using PCSK9 inhibitors were identified. Standard meta-analysis techniques were used to compare these outcomes among patients treated with and without PCSK9 inhibitors and the two US Food and Drug Administration-approved PCSK9 inhibitors, evolocumab and alirocumab...
April 1, 2018: European Heart Journal. Quality of Care & Clinical Outcomes
https://www.readbyqxmd.com/read/29121194/cost-effectiveness-of-colchicine-treatment-on-post-operative-atrial-fibrillation-events-in-patients-of-major-cardiac-surgery
#16
Manish Barman, Mahmoud Tantawy, Mark Sopher, Carsten Lennerz
Aims: Post-operative atrial fibrillation (POAF) occurs in 20-50% of patients amid post-operative stay after Cardiac Surgery. We intend to determine whether colchicine therapy in patients undergoing cardiac surgery is a cost-effective strategy for prevention of POAF. To undertake cost utility analysis and calculate incremental cost utility ratio (ICUR) for colchicine therapy in these subgroup of patients. Methods and results Design: Decision tree model to calculate the ICUR comparing two treatment strategies in patients undergoing cardiac surgery...
April 1, 2018: European Heart Journal. Quality of Care & Clinical Outcomes
https://www.readbyqxmd.com/read/29106473/trends-in-acute-pericarditis-hospitalizations-and-outcomes-among-the-elderly-in-the-usa-1999-2012
#17
Purav Mody, Behnood Bikdeli, Yun Wang, Massimo Imazio, Harlan M Krumholz
Aims: The elderly are at risk of pericarditis from conditions such as malignancy, renal disease, and after cardiac surgery. However, the burden of pericarditis and, especially, the long-term outcomes associated with pericarditis have not been described before among the elderly. Methods and results: We examined hospitalization rates; in-hospital, 30-day, and 1-year all-cause mortality rates; all-cause 30-day readmission rates; length of stay and health care expenditure for Medicare beneficiaries aged 65 years or older with a principal discharge diagnosis of pericarditis from 1999 to 2012...
April 1, 2018: European Heart Journal. Quality of Care & Clinical Outcomes
https://www.readbyqxmd.com/read/29077852/changes-in-symptoms-of-anxiety-and-depression-following-diagnostic-angiography-a-prospective-cohort-study
#18
Tove Aminda Hanssen, Amjid Iqbal, Signe Helene Forsdahl, Thor Trovik, Henrik Schirmer
Aims: Coronary angiography is the gold standard diagnostic test for coronary artery disease (CAD), and the diagnostic results can have an immediate effect on symptoms. The aim of this study was to explore the long-term impact of diagnostic angiography on symptoms of anxiety and depression in a group of patients without previous CAD. Methods and results: The prospective cohort study included 459 consecutive patients undergoing invasive angiography and was approved by the regional board of ethics...
April 1, 2018: European Heart Journal. Quality of Care & Clinical Outcomes
https://www.readbyqxmd.com/read/29045602/does-routinely-collected-patient-reported-outcome-data-represent-the-actual-case-mix-of-elective-coronary-revascularization-patients
#19
Salla Oinasmaa, Jari Heiskanen, Juha Hartikainen, Mikko Hippeläinen, Heikki Miettinen, Janne Martikainen, Risto P Roine, Anna-Maija Tolppanen
Aims: Patient-reported outcomes (PROs) are valuable for effectiveness evaluation, but it is unknown whether the patient views obtained represent the actual case mix. We studied the representativeness of the responses obtained to a routinely administered health-related quality of life (HRQoL) questionnaire in a cardiology unit. Methods and results: Elective coronary artery bypass grafting (CABG; n = 404) and percutaneous coronary intervention (PCI; n = 738) patients operated during June 2012 to August 2014 in the Heart Center, Kuopio University Hospital...
April 1, 2018: European Heart Journal. Quality of Care & Clinical Outcomes
https://www.readbyqxmd.com/read/29462281/linking-hospital-patient-records-for-suspected-or-established-acute-coronary-syndrome-in-a-complex-secondary-care-system-a-proof-of-concept-e-registry-in-nhs-scotland
#20
Iain Findlay, Tamsin Morris, Ruiqi Zhang, Colin McCowan, Sarah Shield, Brian Forbes, Alex McConnachie, Kenneth Mangion, Colin Berry
Aims: To implement secondary care electronic record linkage for patients hospitalised with suspected or known acute coronary syndrome (ACS) in a complex regional healthcare system and evaluate this e-Registry in terms of patterns of service delivery and 1-year outcomes. Methods and Results: Existing electronic hospital records were linked to create episodes of care using (1) a patient administration system, (2) invasive cardiovascular procedure referrals and (3) a catheter laboratory record...
February 16, 2018: European Heart Journal. Quality of Care & Clinical Outcomes
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