Elena Campione, Monia Di Prete, Gaetana Costanza, Andrea Saggini, Sara Agostinelli, Alessandro Terrinoni, Federica Centofanti, Maria Cristina Rapanotti, Luca Bianchi, Amedeo Ferlosio, Maria Giovanna Scioli, Augusto Orlandi
Leiomyomas are smooth muscle-derived benign neoplasms that can affect all organs, most frequently in the uterus. Fumarate hydratase gene (FH) mutation is characterised by an autosomal dominant disease with increased occurrence of renal tumours, but also by cutaneous (CLs) and uterine leiomyomas (ULs). So far, an increased occurrence of skin tumours in non-mutated patients with ULs has not been verified. To this aim, a case-group of women who were FH non-mutated patients surgically treated for ULs ( n = 34) was compared with a control-group ( n = 37) of consecutive age-matched healthy women...
August 4, 2023: Dermatopathology (Basel, Switzerland)