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Dermatopathology (Basel, Switzerland)

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https://www.readbyqxmd.com/read/29719831/a-30-year-old-man-with-hiv-fever-and-a-rash
#1
Radhika Shah, Saami Khalifian, Lyn Duncan, Daniela Kroshinsky, Bonnie Mackool
Patients who present with papular rashes have a wide differential diagnosis particularly in the setting of immune compromise. A 30-year-old male diagnosed with HIV since 2009, never on antiretroviral therapy, with a nadir CD4 count of 333 cells/mm3 and a current viral load of 44,300 copies/mL, presented with a diffuse monomorphic papular eruption that began on his trunk and extremities and subsequently spread to the penis and scrotum, sparing the distal acral sites. A thorough infectious workup revealed a positive rapid plasma reagin (RPR) and varicella IgM and IgG antibodies...
January 2018: Dermatopathology (Basel, Switzerland)
https://www.readbyqxmd.com/read/29719830/a-92-year-old-male-with-eosinophilic-asthma-presenting-with-recurrent-palpable-purpuric-plaques
#2
Nicole A Negbenebor, Saami Khalifian, Ruth K Foreman, Daniela Kroshinsky
Churg-Strauss syndrome or eosinophilic granulomatosis with polyangiitis is a systemic vasculitis affecting the small and medium-sized vasculature. It is commonly associated with asthma and eosinophilia. Most patients are diagnosed at around the age of 40. We report a case of biopsy-confirmed Churg-Strauss syndrome in a 92-year-old male with a history of eosinophilic asthma and peripheral eosinophilia who was later diagnosed with Churg-Strauss syndrome.
January 2018: Dermatopathology (Basel, Switzerland)
https://www.readbyqxmd.com/read/29719829/melanoma-diagnosis-the-importance-of-histopathological-report
#3
Alessandra Filosa, Giorgio Filosa
No abstract text is available yet for this article.
January 2018: Dermatopathology (Basel, Switzerland)
https://www.readbyqxmd.com/read/29719828/spitzoid-neoplasms-suggestions-from-genomic-aberrations
#4
Carmelo Urso
No abstract text is available yet for this article.
January 2018: Dermatopathology (Basel, Switzerland)
https://www.readbyqxmd.com/read/29719827/sentinel-node-biopsy-in-melanoma-a-short-update
#5
REVIEW
Gerardo Ferrara, Antonietta Partenzi, Alessandra Filosa
Several controversies are still ongoing about sentinel node biopsy in melanoma. It is basically a staging procedure for melanoma > 0.75 mm in thickness or for thinner melanoma in the presence of ulceration, high mitotic rate, and/or lymphovascular invasion. Complete lymph node dissection after a positive sentinel node can also allow a better locoregional disease control but seems not to prevent the development of distant metastases. The use of sentinel node biopsy in atypical Spitz tumors should be discouraged because of their peculiar biological properties...
January 2018: Dermatopathology (Basel, Switzerland)
https://www.readbyqxmd.com/read/29719826/obesity-associated-lymphedematous-mucinosis-two-further-cases-and-review-of-the-literature
#6
REVIEW
Caterina Ferreli, Anna Luisa Pinna, Luca Pilloni, Marialuisa Corbeddu, Franco Rongioletti
Cutaneous mucinoses are a group of conditions characterized by increased amounts of acid mucin in the dermis. They can be generalized or localized and occur isolated or in the setting of systemic diseases. Obesity-associated lymphedematous mucinosis is a distinct variant of mucinosis occurring in obese patients without any thyroid dysfunction. So far, only few cases of this rare condition have been reported in the English literature. Here, we describe two new cases and discuss some histological differences with the pretibial myxedema...
January 2018: Dermatopathology (Basel, Switzerland)
https://www.readbyqxmd.com/read/29719825/pathogenesis-of-psoriasis-focus-on-autoinflammation
#7
Angelo Valerio Marzano, Federica Derlino, Emilio Francesco Berti
No abstract text is available yet for this article.
January 2018: Dermatopathology (Basel, Switzerland)
https://www.readbyqxmd.com/read/29719824/panniculitides-in-rheumatoid-syndromes-the-role-of-histopathology
#8
Carlo Tomasini
No abstract text is available yet for this article.
January 2018: Dermatopathology (Basel, Switzerland)
https://www.readbyqxmd.com/read/29719823/mycetomas-the-experience-of-the-dermatology-unit-of-the-university-of-milan
#9
Gianluca Nazzaro, Stefano Veraldi
No abstract text is available yet for this article.
January 2018: Dermatopathology (Basel, Switzerland)
https://www.readbyqxmd.com/read/29719822/an-81-year-old-woman-with-recalcitrant-blisters
#10
Daniel C Butler
Epidermolysis bullosa acquisita (EBA) is a rare mucocutaneous blistering disorder with typical onset in adulthood. Diagnosis and management can be difficult owing to the variability in presentation and clinical manifestation. In this case, we explore a case of EBA as well as provide a general overview of the condition and its variants.
January 2018: Dermatopathology (Basel, Switzerland)
https://www.readbyqxmd.com/read/29594106/gangrenous-chickenpox-with-atypical-clinical-and-histopathological-findings
#11
Leonardo Bianchi, Stefano Simonetti, Katharina Hansel, Franco Baldelli, Elisabetta Schiaroli, Luca Stingeni
No abstract text is available yet for this article.
January 2018: Dermatopathology (Basel, Switzerland)
https://www.readbyqxmd.com/read/29594105/neutrophilic-dermatoses-in-autoimmune-diseases-report-of-two-cases-associated-with-autoimmune-thyroiditis
#12
Angelo Cassisa
The term "neutrophilic dermatoses" includes a rare inflammatory pattern characterized by neutrophil-rich cutaneous infiltrate. Both innate and adaptive immune pathways may be involved in neutrophil recruitment. Occasionally, neutrophilic dermatoses may occur in association with autoimmune thyroiditis. Pathogenetic aspects of this autoimmune disorder may elucidate their possible connection. Two exemplificative cases are taken as a pretext for a short review of this topic.
January 2018: Dermatopathology (Basel, Switzerland)
https://www.readbyqxmd.com/read/29594104/lymphocytic-lobular-panniculitis-a-diagnostic-challenge
#13
Silvia Alberti-Violetti, Emilio Berti
No abstract text is available yet for this article.
January 2018: Dermatopathology (Basel, Switzerland)
https://www.readbyqxmd.com/read/29457000/dysplastic-nevus-a-fake-lesion
#14
Guido Collina
No abstract text is available yet for this article.
January 2017: Dermatopathology (Basel, Switzerland)
https://www.readbyqxmd.com/read/29456999/a-53-year-old-male-with-relapsed-diffuse-large-b-cell-lymphoma-on-chemotherapy-with-a-new-leg-lesion
#15
Connie R Shi, Sarah N Robinson, Avery LaChance, Martin C Mihm, Daniela Kroshinsky
Patients with underlying malignancy who develop new skin findings while acutely ill often require skin biopsy for histologic evaluation and/or culture to reach a diagnosis. Here, we present the case of a 53-year-old male with relapsed diffuse large B-cell lymphoma on chemotherapy who developed new skin lesions on the leg. On exam, there were 2 nickel-sized, erythematous to violaceous round plaques with central necrotic cores on the right lower leg with relatively nonspecific clinical features for which the initial differential diagnosis was broad...
January 2017: Dermatopathology (Basel, Switzerland)
https://www.readbyqxmd.com/read/29456998/a-12-month-old-healthy-girl-with-a-new-oral-ulcer-and-chronic-diaper-rash
#16
Hannah Song, Johanna S Song, Elizabeth B Wallace, Leonard B Kaban, Mary S Huang, Stefan Kraft, Martin C Mihm, Daniela Kroshinsky
A 12-month-old healthy girl presented with a chronic diaper rash. Physical examination demonstrated crusting of the scalp, erythematous papules with surrounding petechiae on the lower abdomen, and an intraoral palatal ulcer. Further imaging demonstrated bone involvement. Histopathologic examination of involved skin and the intraoral ulcer demonstrated epithelioid histiocytes with "coffee bean-shaped" nuclei, staining positive for CD1a and langerin by immunohistochemistry, consistent with Langerhans cell histiocytosis (LCH)...
January 2017: Dermatopathology (Basel, Switzerland)
https://www.readbyqxmd.com/read/29456997/a-71-year-old-female-with-myocardial-infarction-and-long-standing-ulcers-on-the-thigh
#17
Eduardo De Flammineis, Patrick M Mulvaney, Stefan Kraft, Martin C Mihm, Shinjita Das, Daniela Kroshinsky
Calciphylaxis is most commonly encountered in patients with end-stage renal disease; however, it is increasingly observed in nonuremic patients as well. It is important to consider and diagnose nonuremic calciphylaxis early, as prompt treatment and mitigation of associated risk factors is essential to improve long-term outcomes for these patients. Here, we present the case of a 71-year-old woman with atrial fibrillation on warfarin, but without renal disease, who presented with two long-standing ulcers on her thigh and was diagnosed with the aid of biopsy with calciphylaxis...
January 2017: Dermatopathology (Basel, Switzerland)
https://www.readbyqxmd.com/read/29456996/a-65-year-old-male-with-primary-central-nervous-system-diffuse-large-b-cell-lymphoma-on-nivolumab-with-oral-mucositis-and-targetoid-plaques
#18
Severine Cao, Pooyan Rohani, Rosalynn M Nazarian, Daniela Kroshinsky
Background/Aims: The development of programmed cell death-1 (PD-1) inhibitors has greatly improved patient outcomes in the treatment of a variety of advanced malignancies. These novel immunotherapies are not without adverse effects, the most common of which are dermatologic. Methods: We report our experience with an atypical erythema multiforme-like eruption in a patient with primary central nervous system diffuse large B-cell lymphoma treated with nivolumab. Results: The patient presented with oral mucositis and scattered erythematous papules which progressed to targetoid purpuric plaques with hyperkeratotic centers...
January 2017: Dermatopathology (Basel, Switzerland)
https://www.readbyqxmd.com/read/29456995/a-25-year-old-male-with-orogenital-ulcers-rash-and-difficulty-swallowing
#19
Lauren N Ko, Allireza Alloo, William M Lin, Mai P Hoang, Daniela Kroshinsky
A 25-year-old otherwise healthy male presented with new-onset odynophagia, rash, and orogenital ulcers. Despite treatment with antibiotics for presumed bacterial pharyngitis, the patient remained symptomatic, with abnormal vital signs and laboratory values. Upon dermatology consultation and histopathologic correlation, he was diagnosed with Behçet disease. Behçet disease is a rare rheumatologic condition that presents with recurrent oral ulcers and varying degrees of ophthalmic, neurologic, cardiac, and vascular disease...
January 2017: Dermatopathology (Basel, Switzerland)
https://www.readbyqxmd.com/read/29456994/benign-cutaneous-peripheral-nerve-sheath-tumor-with-hybrid-features-report-of-two-cases-with-schwannoma-perineurioma-and-schwannoma-neurofibroma-components
#20
Shirien Shanouda, Gürkan Kaya
Hybrid benign peripheral nerve sheath tumors are rare tumors exhibiting areas of more than one neural neoplasm such as schwannoma/neurofibroma, neurofibroma/perineurioma, or schwannoma/perineurioma. These tumors usually arise in the skin of the extremities and trunk, and less commonly affect extracutaneous sites. Here we report two cases of these tumors exhibiting hybrid features of schwannoma/perineurioma and schwannoma/neurofibroma located in the scalp and the ankle, respectively.
January 2017: Dermatopathology (Basel, Switzerland)
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