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Journal of Experimental Orthopaedics

Nick F J Hilgersom, Tim Horeman-Franse, Ronald L A W Bleys, Denise Eygendaal, Michel P J van den Bekerom, Gabriëlle J M Tuijthof
BACKGROUND: Elbow arthroscopy is a difficult surgical technique. Objective metrics can be used to improve safe and effective training in elbow arthroscopy. Force exerted on the elbow tissue during arthroscopy can be a measure of safe tissue manipulation. The purpose of this study was to determine the force magnitude and force direction used by experts during arthroscopic elbow navigation in cadaveric specimens and assess their applicability in elbow arthroscopy training. METHODS: Two cadaveric elbows were mounted on a Force Measurement Table (FMT) that allowed 3-dimensional measurements (x-, y-, and z-plane) of the forces exerted on the elbow...
October 11, 2018: Journal of Experimental Orthopaedics
Thomas Bandholm, Thomas W Wainwright, Henrik Kehlet
Exercise-based interventions applied before and after total hip and knee arthroplasty (THA and TKA, respectively) have been investigated for a number of years, based on the assumption that they will enhance post-operative recovery. Although recent studies suggest that high-volume, pre-operative exercise may enhance post-operative recovery after TKA, studies of post-operative exercise-based interventions, have not found superiority of one exercise regime over another. It seems, however, that post-operative, exercise-based, rehabilitation is superior to no or minimal rehabilitation after THA and TKA...
October 11, 2018: Journal of Experimental Orthopaedics
Robin Mawson, Michael J Creech, Devin C Peterson, Forough Farrokhyar, Olufemi R Ayeni
BACKGROUND: Participation in youth soccer carries a significant risk of injury, most commonly non-contact injuries of the lower extremity. A growing body of research supports the use of neuromuscular interventions by teams to prevent such injuries, yet the uptake of these recommendations by soccer teams remains largely unexplored. The purposes of the study were to determine (1) the level of awareness by youth coaches of injury prevention programs and their efficacy; (2) the number of youth coaches that use these interventions; and (3) barriers and potential facilitators to implementing a sustainable injury prevention program...
October 11, 2018: Journal of Experimental Orthopaedics
Colter R Wichern, Kathryn C Skoglund, Joseph G O'Sullivan, Anora K Burwell, Joseph T Nguyen, Andrea Herzka, Jacqueline M Brady
BACKGROUND: The all-inside cruciate ligament graft preparation technique has become popular due to its utility in sparing a growing physis, preserving a tendon in ACL surgery, and/or reduction of pain. However, few studies have compared graft preparation techniques to determine the ideal construct for cruciate ligament reconstruction. We sought to compare biomechanical properties of two quadrupled all-inside cruciate ligament graft preparation techniques and three alternative all-inside graft preparation techniques that may be used when the available tendon is too short to be quadrupled...
October 10, 2018: Journal of Experimental Orthopaedics
M Ettinger, R Karkosch, H Horstmann, P Savov, T Calliess, T Smith, M Petri
BACKGROUND: Reliable biomechanical data about the strength of different tibial extracortical graft fixation devices is sparse. This biomechanical study compares the properties of tibial graft fixation in ACL reconstruction with either the ACL Tight Rope™ or the Rigid Loop Adjustable™ device. The hypothesis was that both fixation devices would provide comparable results concerning gap formation during cyclic loading and ultimate failure load. METHODS: Sixteen sawbone tibiae (Sawbones™) underwent extracortical fixation of porcine flexor digitorum profundus grafts for ACL reconstruction...
September 29, 2018: Journal of Experimental Orthopaedics
Annika Piirainen, Jukka Huopio, Hannu Kokki, Anu Holopainen, Teemu Pajunen, Kari Pulkki, Merja Kokki
BACKGROUND: The feasibility of novel kidney injury biomarkers in consecutive patients having total knee arthroplasty with local infiltration analgesia was evaluated. METHODS: We enrolled 30 patients scheduled for elective unilateral total knee arthroplasty. Paired plasma and urine samples were taken before surgery and at 4 h, 24 h and 48 h after surgery to measure creatinine, cystatin C, neutrophil gelatinase associated lipocalin, kidney injury molecule-1, interleukin-18 and liver-type fatty acid-binding protein...
September 25, 2018: Journal of Experimental Orthopaedics
Salvatore Bisicchia, Flavia Botti, Cosimo Tudisco
BACKGROUND: Discoid lateral meniscus is the most frequent variant of the meniscus. Although the histology of normal menisci in children and in adults has been well described, few studies have focused on the histology of discoid menisci. Furthermore, most of the patients in those studies were adults. The aim of the present study was to report the histological findings of discoid lateral meniscus in a group of children and adolescents, aged between 9 and 18, after arthroscopic partial resection, focusing on cellularity, arrangement of collagen fibers, and vascularity of the excised fragments...
September 24, 2018: Journal of Experimental Orthopaedics
F Abat, H Alfredson, M Cucchiarini, H Madry, A Marmotti, C Mouton, J M Oliveira, H Pereira, G M Peretti, C Spang, J Stephen, C J A van Bergen, L de Girolamo
The treatment of painful chronic tendinopathy is challenging. Multiple non-invasive and tendon-invasive methods are used. When traditional non-invasive treatments fail, the injections of platelet-rich plasma autologous blood or cortisone have become increasingly favored. However, there is little scientific evidence from human studies supporting injection treatment. As the last resort, intra- or peritendinous open or endoscopic surgery are employed even though these also show varying results. This ESSKA basic science committee current concepts review follows the first part on the biology, biomechanics and anatomy of tendinopathies, to provide a comprehensive overview of the latest treatment options for tendinopathy as reported in the literature...
September 24, 2018: Journal of Experimental Orthopaedics
Yoshinori Ohashi, Junsuke Nakase, Kengo Shimozaki, Kojun Torigoe, Hiroyuki Tsuchiya
BACKGROUND: Using the film model method, the process whereby a substance called tendon gel is secreted from transected tendon ends and changed into a tendon after application of a traction force is known. The objective of this study was to investigate the association between mechanical properties in the early stages of tendon regeneration and time by using the film model method. METHOD: Adult male ddY mice, closed colony mice established and maintained in Japan, were prepared for each experimental group...
September 21, 2018: Journal of Experimental Orthopaedics
Stephanie N Moore-Lotridge, William K Oelsner, Yael Ihejirika, Mihir J Desai, Sandra S Gebhart, Jonathan G Schoenecker
BACKGROUND: Peri-articular injury may result in functional deficits and pain. In particular, post-traumatic elbow stiffness is a debilitating condition, precluding patients from performing activities of daily living. As such, clinicians and basic scientists alike, aim to develop novel therapeutic interventions to prevent and treat elbow stiffness; thereby reducing patient morbidity. Yet, there is a paucity of pre-clinical models of peri-articular stiffness, especially of the upper extremity, necessary to develop and test the efficacy of therapeutics...
September 18, 2018: Journal of Experimental Orthopaedics
Johannes Barth, Jérôme Garret, Achilleas Boutsiadis, Etienne Sautier, Laurent Geais, Hugo Bothorel, Arnaud Godenèche
BACKGROUND: While most anatomic TSA stems allow some intra-operative adjustments, the default configuration assumes that head offset is directly proportional to stem diameter. Some authors reported that humeral head diameter is proportional to intra-medullary canal width and humeral head offset, but none investigated the direct relationship between head offset and endosteal measurements. The purpose of the study was to determine whether global humeral head offset is proportional to intramedullary canal width at the distal metaphysis and proximal diaphysis...
September 12, 2018: Journal of Experimental Orthopaedics
Joanna Stephen, Avinash Alva, Punyawan Lumpaopong, Andy Williams, Andrew A Amis
BACKGROUND: Vastus Medialis Muscles (VMM) damage has been widely identified following patellar dislocation. Rehabilitation programmes have been suggested to strengthen the VMM and reduce clinical symptoms of pain and instability. This controlled laboratory study investigated the hypothesis that reduced Vastus Medialis Obliquus (VMO) and Vastus Medialis Longus (VML) muscle tension would alter patellar tracking, stability and PFJ contact pressures. METHODS: Nine fresh-frozen dissected cadaveric knees were mounted in a rig with the quadriceps and iliotibial band loaded to 205 N...
September 10, 2018: Journal of Experimental Orthopaedics
Pierre-Louis Ricci, Stefan Maas, Jens Kelm, Torsten Gerich
BACKGROUND: The objective of the study is to investigate the load transmission within the pelvic ring under physiological loading during gait and to correlate these results with clinical findings. In a second approach, we analysed how load distribution is altered by fractures of the anterior pelvic ring. METHODS: Muscle forces and joint reaction forces are calculated by inverse dynamics and implemented in a finite element pelvis model including the joints. RESULTS: With the intact configuration and according to the moment of the gait, left and right superior and inferior rami show the highest stresses of the model, corresponding to the typical location of an anterior pelvic ring fracture...
September 3, 2018: Journal of Experimental Orthopaedics
Ryota Katsumi, Tomoharu Mochizuki, Takashi Sato, Koichi Kobayashi, Satoshi Watanabe, Osamu Tanifuji, Naoto Endo
BACKGROUND: Humans support their bodies exclusively by vertical balance in bipedal locomotion, and the body, especially the lower extremity, generally changes with age. Sex and body constitution are assumed to be associated with lower extremity alignment, but this association remains to be elucidated. This study sought to clarify this association in healthy, elderly, non-obese humans in a Japanese population. METHODS: The present study investigated 55 healthy volunteers (mean age: 70 ± 6 years)...
August 22, 2018: Journal of Experimental Orthopaedics
Juha-Sampo Suomalainen, Gideon Regalado, Antti Joukainen, Tommi Kääriäinen, Mervi Könönen, Hannu Manninen, Petri Sipola, Hannu Kokki
BACKGROUND: Measurement of the tibial tubercle-trochlear groove (TT-TG) distance is used to assess patellofemoral instability and rotation. Since patellofemoral instability and acute patellar dislocation are common among adolescents, it is important to clarify the relationship between TT-TG distance and various flexion and extension angles in asymptomatic children. The purpose of the present study was to determine how knee flexion and extension influence TT-TG-distance values measured using 3D imaging in an anatomic axial plane among asymptomatic adolescents...
August 16, 2018: Journal of Experimental Orthopaedics
David R Lionberger, Justin Samorajski, Charlie D Wilson, Andreana Rivera
BACKGROUND: Clinicians are often faced with the decision whether to revise a painful total knee replacement in patients who have chronic vague pain with no apparent explanation. A sensitive metal testing assay called the lymphocyte stimulation test has been used to detect nickel sensitization in patients with orthopedic implants. We hypothesize that nickel sensitization plays a role in the pathology of failed joint arthroplasty in patients with unexplained dissatisfaction. METHODS: 32 patients with symptomatic total knee arthroplasty without obvious mechanical findings were tested prior to revision surgery...
August 14, 2018: Journal of Experimental Orthopaedics
Malou E Slichter, Nienke Wolterbeek, K Gie Auw Yang, Jacco A C Zijl, Tom M Piscaer
BACKGROUND: Rotational instability of the knee may persist after anterior cruciate ligament (ACL) reconstruction, which may be due to insufficiency of anterolateral stabilizing structures. However, no reliable diagnostic tool or physical examination test is available for identifying patients with anterolateral rotatory instability (ALRI). As shown in cadaveric studies, static internal rotation of the knee is increased in higher flexion angles of the knee after severing the anterolateral structures...
August 9, 2018: Journal of Experimental Orthopaedics
Arnaud Diffo Kaze, Stefan Maas, Slawomir Kedziora, James Belsey, Alexander Haupert, Claude Wolf, Alexander Hoffmann, Dietrich Pape
BACKGROUND: Many different fixation devices are used to maintain the correction angle after medial open wedge high tibial osteotomy (MOWHTO). Each device must provide at least sufficient mechanical stability to avoid loss of correction and unwanted fracture of the contralateral cortex until the bone heals. In the present study, the mechanical stability of following different implants was compared: the TomoFix small stature (sm), the TomoFix standard (std), the Contour Lock, the iBalance and the second generation PEEKPower...
August 8, 2018: Journal of Experimental Orthopaedics
Jonathan P Evans, Jeremy Metz, Rahul Anaspure, William J Thomas, Andrew King, Vicki A Goodwin, Chris D Smith
BACKGROUND: Injections into the tendinous portion of the common extensor origin are a common intervention in the treatment of Lateral Elbow Tendinopathy (LET). Clinical trials report a heterogeneous selection of injectate volumes and delivery techniques, with systematic reviews finding no clear consensus. The aim of this study was to assess the intratendinous distribution and surrounding tissue contamination of ultrasound-guided injections into the Common Extensor Tendon (CET) of the elbow...
July 18, 2018: Journal of Experimental Orthopaedics
Ichiro Tonogai, Fumio Hayashi, Toshiyuki Iwame, Tomoya Takasago, Tetsuya Matsuura, Koichi Sairyo
BACKGROUND: Skeletal muscle fibrosis caused by an increase in collagen deposition often occurs after distraction osteogenesis. Although studies are available reporting the effects of platelet-rich plasma (PRP) on tissue healing following injury, current findings remain controversial. This study focused on determining whether PRP reduces skeletal muscle fibrosis caused by distraction osteogenesis. METHODS: Tibial osteotomies were performed on 8-week-old wild type mice, and tibiae were distracted at a rate of 0...
July 13, 2018: Journal of Experimental Orthopaedics
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