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Journal of Experimental Orthopaedics

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https://www.readbyqxmd.com/read/28224374/mri-findings-of-knee-abnormalities-in-adolescent-and-adult-volleyball-players
#1
Heide Boeth, Aoife MacMahon, Felix Eckstein, Gerd Diederichs, Arne Schlausch, Wolfgang Wirth, Georg N Duda
BACKGROUND: To longitudinally and cross-sectionally evaluate knee abnormalities by sex and age in adolescent and adult volleyball athletes over 2 years using magnetic resonance imaging (MRI). METHODS: Thirty-six high-level volleyball athletes (18 adolescents: 56% female, mean age 16.0 ± 0.8 years; and 18 adults: 50% female, mean age 46.8 ± 5.1 years) were imaged by MRI at BL and at 2-year follow-up (FU). Prevalence and severity of cartilage lesions, subarticular bone marrow lesions (BMLs), subarticular cysts, osteophytes, and ligament and meniscus integrity were evaluated by sex and by age cohort (adolescents and adults) using the whole-organ MRI score (WORMS)...
December 2017: Journal of Experimental Orthopaedics
https://www.readbyqxmd.com/read/28176273/the-haematoma-and-its-role-in-bone-healing
#2
REVIEW
H Schell, G N Duda, A Peters, S Tsitsilonis, K A Johnson, K Schmidt-Bleek
Fracture treatment is an old endeavour intended to promote bone healing and to also enable early loading and regain of function in the injured limb. However, in today's clinical routine the healing potential of the initial fracture haematoma is still not fully recognized. The Arbeitsgemeinschaft für Osteosynthesefragen (AO) formed in Switzerland in 1956 formulated four AO principles of fracture treatment which are still valid today. Fracture treatment strategies have continued to evolve further, as for example the relatively new concept of minimally invasive plate osteosynthesis (MIPO)...
December 2017: Journal of Experimental Orthopaedics
https://www.readbyqxmd.com/read/28176272/effects-of-combined-raav-mediated-tgf-%C3%AE-and-sox9-gene-transfer-and-overexpression-on-the-metabolic-and-chondrogenic-activities-in-human-bone-marrow-aspirates
#3
Ke Tao, Ana Rey-Rico, Janina Frisch, Jagadeesh Kumar Venkatesan, Gertrud Schmitt, Henning Madry, Jianhao Lin, Magali Cucchiarini
BACKGROUND: Transplantation of genetically modified bone marrow concentrates is an attractive approach to conveniently activate the chondrogenic differentiation processes as a means to improve the intrinsic repair capacities of damaged articular cartilage. METHODS: Human bone marrow aspirates were co-transduced with recombinant adeno-associated virus (rAAV) vectors to overexpress the pleiotropic transformation growth factor beta (TGF-β) and the cartilage-specific transcription factor sox9 as a means to enhance the chondroreparative processes in conditions of specific lineage differentiation...
December 2017: Journal of Experimental Orthopaedics
https://www.readbyqxmd.com/read/28144820/a-preclinical-numerical-assessment-of-a-polyetheretherketone-femoral-component-in-total-knee-arthroplasty-during-gait
#4
Lennert de Ruiter, Dennis Janssen, Adam Briscoe, Nico Verdonschot
BACKGROUND: Conventional total knee replacement designs show high success rates but in the long term, the stiff metal components may affect bone quality of the distal femur. In this study we introduce an all-polymer total knee replacement device containing a PEEK femoral component on an UHMWPE tibial implant and study its mechanical integrity, fixation, and stress shielding of the periprosthetic femur. METHODS: The implant was analysed in finite element simulations of level gait, adopted from the ISO 14243-1 standard...
December 2017: Journal of Experimental Orthopaedics
https://www.readbyqxmd.com/read/28124287/biomechanical-testing-of-transcapsular-meniscal-repair
#5
Ryo Iuchi, Tatsuo Mae, Konsei Shino, Tomohiko Matsuo, Hideki Yoshikawa, Ken Nakata
BACKGROUND: All of previous biomechanical studies on meniscal repair have examined the meniscus itself without synovial membrane and capsule, although in the clinical setting, the meniscal repair is generally performed including capsule. Therefore, biomechanical properties of transcapsular meniscal repair are unclear. Thus, this study aimed to clarify the biomechanical properties of transcapsular meniscal repair. METHODS: In 70 porcine femur-medial meniscus-tibia complexes with capsules, longitudinal meniscal tears were repaired using different suture techniques (inside-out or all-inside technique), suture methods (vertical or horizontal methods), and numbers of sutures (single or double)...
December 2017: Journal of Experimental Orthopaedics
https://www.readbyqxmd.com/read/28116554/patient-perceptions-regarding-physician-reimbursements-wait-times-and-out-of-pocket-payments-for-anterior-cruciate-ligament-reconstruction-in-ontario
#6
Muzammil Memon, Lydia Ginsberg, Darren de Sa, Andrew Nashed, Nicole Simunovic, Mark Phillips, Matthew Denkers, Rick Ogilvie, Devin Peterson, Olufemi R Ayeni
BACKGROUND: Currently, there is a lack of knowledge regarding patient perceptions surrounding physician reimbursements, appropriate wait times, and out-of-pocket payment options for anterior cruciate ligament reconstruction (ACLR). Our objective was to determine the current state of these perceptions in an Ontario setting. METHODS: A survey was developed and pretested to address patient perceptions about physician reimbursements, appropriate wait times, and out-of-pocket payment options for ACLR using a focus group of experts and by reviewing prior surveys...
December 2017: Journal of Experimental Orthopaedics
https://www.readbyqxmd.com/read/28012152/erratum-to-bone-marrow-aspirate-concentrate-for-the-treatment-of-osteochondral-lesions-of-the-talus-a-systematic-review-of-outcomes
#7
Jorge Chahla, Mark E Cinque, Jason M Schon, Daniel J Liechti, Lauren M Matheny, Robert F LaPrade, Thomas O Clanton
No abstract text is available yet for this article.
December 2016: Journal of Experimental Orthopaedics
https://www.readbyqxmd.com/read/27957713/drill-wobble-effect-on-femoral-tunnel-aperture-during-anterior-cruciate-ligament-reconstruction
#8
Naser Alnusif, Adam Hart, Maher Baroudi, Robert Marien, Mark Burman, Paul A Martineau
BACKGROUND: In anterior cruciate ligament reconstruction performed using cortical button fixation on the femur, we have observed a "wobble" effect that can occur when a cannulated femoral drill is used over a guide pin that is not securely fixed in bone. Our study assessed the effect of drill "wobble" on femoral tunnel aperture in sawbones. METHODS: Femoral tunnels were drilled in sawbones, which had been divided in two groups of 10 each, per drilling technique...
December 2016: Journal of Experimental Orthopaedics
https://www.readbyqxmd.com/read/27943224/quantitative-computed-tomography-qct-derived-bone-mineral-density-bmd-in-finite-element-studies-a-review-of-the-literature
#9
REVIEW
Nikolas K Knowles, Jacob M Reeves, Louis M Ferreira
BACKGROUND: Finite element modeling of human bone provides a powerful tool to evaluate a wide variety of outcomes in a highly repeatable and parametric manner. These models are most often derived from computed tomography data, with mechanical properties related to bone mineral density (BMD) from the x-ray energy attenuation provided from this data. To increase accuracy, many researchers report the use of quantitative computed tomography (QCT), in which a calibration phantom is used during image acquisition to improve the estimation of BMD...
December 2016: Journal of Experimental Orthopaedics
https://www.readbyqxmd.com/read/27928740/anatomical-study-comparing-the-human-sheep-and-pig-knee-meniscus
#10
Talal Takroni, Leila Laouar, Adetola Adesida, Janet A W Elliott, Nadr M Jomha
BACKGROUND: Animal models are commonly used in investigating new treatment options for knee joint injuries including injuries to the meniscus. The reliability and applicability of these models to replicate findings in humans depends on determining the most suitable animal proxy. Therefore, this study was designed to compare the wet weight, volume and dimensions of the human meniscus with two commonly used animal models: sheep and pig. METHODS: Human menisci (n = 6 pairs) were obtained from the knee joints of cadaveric male donors...
December 2016: Journal of Experimental Orthopaedics
https://www.readbyqxmd.com/read/27854082/randomized-controlled-trial-comparing-the-effectiveness-of-the-ultrasound-guided-galvanic-electrolysis-technique-usget-versus-conventional-electro-physiotherapeutic-treatment-on-patellar-tendinopathy
#11
F Abat, J L Sánchez-Sánchez, A M Martín-Nogueras, J I Calvo-Arenillas, J Yajeya, R Méndez-Sánchez, J C Monllau, P E Gelber
BACKGROUND: Patellar tendinopathy has a high prevalence rate among athletes. Different therapeutic options can be found in the current literature, but none of them has been clearly established as the gold standard. The purpose of this study is to compare, in a randomized controlled trial, the clinical efficacy of eccentric exercise combined with either an ultrasound-guided galvanic electrolysis technique (USGET) or conventional electrophysiotherapy to treat patellar tendinopathy. METHODS: Sixty patients diagnosed with patellar tendinopathy were randomized into two groups...
December 2016: Journal of Experimental Orthopaedics
https://www.readbyqxmd.com/read/27813021/bone-marrow-aspirate-concentrate-for-the-treatment-of-osteochondral-lesions-of-the-talus-a-systematic-review-of-outcomes
#12
REVIEW
Jorge Chahla, Mark E Cinque, Jason M Shon, Daniel J Liechti, Lauren M Matheny, Robert F LaPrade, Thomas O Clanton
BACKGROUND: The goal of this perform a systematic review on the outcomes of bone marrow aspirate concentrate (BMAC) for the treatment of chondral defects and osteoarthritis (OA) of the talus. RESULTS: The systematic search performed identified 47 studies after duplicates were removed. After inclusion criteria were applied four studies were considered for insightful analysis for the treatment of focal chondral defects in the foot and ankle with the use of BMAC. Three studies were retrospective and one study was prospective in nature...
December 2016: Journal of Experimental Orthopaedics
https://www.readbyqxmd.com/read/27813020/new-insight-in-the-architecture-of-the-quadriceps-tendon
#13
Karl Grob, Mirjana Manestar, Luis Filgueira, Timothy Ackland, Helen Gilbey, Markus S Kuster
BACKGROUND: Published data regarding the structure of the quadriceps tendon are diverse. Dissection of the quadriceps muscle group revealed that beside the rectus femoris, vastus lateralis, vastus intermedius and vastus medialis a fifth muscle component- named the tensor vastus intermedius consistently fused into quadriceps tendon. It can be hypothesized that all these elements of the extensor apparatus of the knee joint must also be represented in the quadriceps tendon. This study investigated the multi-layered quadriceps tendon with special emphasis on all components of the quadriceps muscle group including the newly discovered tensor vastus intermedius...
December 2016: Journal of Experimental Orthopaedics
https://www.readbyqxmd.com/read/27813019/knee-donor-site-morbidity-after-mosaicplasty-a-systematic-review
#14
REVIEW
Renato Andrade, Sebastiano Vasta, Rogério Pereira, Hélder Pereira, Rocco Papalia, Mustafa Karahan, J Miguel Oliveira, Rui L Reis, João Espregueira-Mendes
BACKGROUND: Mosaicplasty has been associated with good short- to long-term results. Nevertheless, the osteochondral harvesting is restricted to the donor-site area available and it may lead to significant donor-site morbidity. PURPOSE: Provide an overview of donor-site morbidity associated with harvesting of osteochondral plugs from the knee joint in mosaicplasty procedure. METHODS: Comprehensive search using Pubmed, Cochrane Library, SPORTDiscus and CINAHL databases was carried out through 10(th) October of 2016...
December 2016: Journal of Experimental Orthopaedics
https://www.readbyqxmd.com/read/27807812/inflammatory-cytokine-levels-in-synovial-fluid-3-4%C3%A2-days-postoperatively-and-its-correlation-with-early-phase-functional-recovery-after-anterior-cruciate-ligament-reconstruction-a-cohort-study
#15
Makiko Inoue, Takeshi Muneta, Miyoko Ojima, Kaori Nakamura, Hideyuki Koga, Ichiro Sekiya, Mutsumi Okazaki, Kunikazu Tsuji
BACKGROUND: Synovial fluid was collected prior to and at 3 to 4 days after ACL reconstruction to investigate the correlation between inflammatory cytokine levels in the acute phase after surgery and physical functional recovery at 3 months postoperatively. METHODS:  For this purpose, 79 patients with ACL reconstruction using semitendinosus tendons were included in the study. Median days from injury to surgery were 80 days (13-291 days). Synovial fluid was obtained just before surgery and at 3 to 4 days after surgery...
December 2016: Journal of Experimental Orthopaedics
https://www.readbyqxmd.com/read/27783350/knee-joint-kinematics-with-dynamic-augmentation-of-primary-anterior-cruciate-ligament-repair-a-biomechanical-study
#16
Janosch Häberli, Philipp Henle, Yves P Acklin, Ivan Zderic, Boyko Gueorguiev
BACKGROUND: Dynamic augmentation of anterior cruciate ligament tears seems to reduce anteroposterior knee translation close to the pre-injury level. The aim of the present study is to biomechanically investigate the course of translation during a simulated early post-operative phase. It is hypothesized that anteroposterior translation is maintained at the immediate post-operative level over a simulated rehabilitation period of 50'000 gait cycles. METHODS: Eight fresh-frozen human cadaveric knee joints from donors with a mean age of 35...
December 2016: Journal of Experimental Orthopaedics
https://www.readbyqxmd.com/read/27734283/the-cross-sectional-shape-of-the-fourfold-semitendinosus-tendon-is-oval-not-round
#17
Takeshi Oshima, Junsuke Nakase, Hitoaki Numata, Yasushi Takata, Hiroyuki Tsuchiya
BACKGROUND: The looped side of the semitendinosus tendon (ST) graft (i.e., the side inserted into the femoral tunnel during anterior cruciate ligament reconstruction) appears to be oval rather than round. The purpose of this study was to investigate the cross section of the fourfold semitendinosus tendon graft and, more specifically, the differences in pressure exerted by a rounded rectangular tunnel versus a round femoral tunnel. METHODS: Seven STs were harvested from cadaveric knees and a fourfold ST graft was made...
December 2016: Journal of Experimental Orthopaedics
https://www.readbyqxmd.com/read/27730595/three-dimensional-kinematic-and-kinetic-analysis-of-knee-rotational-stability-in-acl-deficient-patients-during-walking-running-and-pivoting
#18
Marie Bagger Bohn, Annemette Krintel Petersen, Dennis Brandborg Nielsen, Henrik Sørensen, Martin Lind
BACKGROUND: Anterior cruciate ligament (ACL) deficiency leads to altered stability of the knee. The purpose of this study was to compare the dynamic, rotational stability of the knee, expressed as rotational stiffness, between anterior cruciate ligament-deficient (ACLD) knees, their contralateral intact knees (ACLI) and a knee healthy control group during walking, running and 90° pivoting. We hypothesized a larger tibial internal rotation, a smaller knee joint external moment and a lower rotational stiffness in the ACLD group compared to the ACLI and the control group...
December 2016: Journal of Experimental Orthopaedics
https://www.readbyqxmd.com/read/27730594/erratum-to-imaging-the-implant-soft-tissue-interactions-in-total-knee-arthroplasty
#19
Michel P Bonnin, Tom Van Hoof, Arnoud De Kok, Matthias Verstraete, Catherine Van der Straeten, Mo Saffarini, Jan Victor
No abstract text is available yet for this article.
December 2016: Journal of Experimental Orthopaedics
https://www.readbyqxmd.com/read/27714703/sustained-delivery-of-recombinant-human-bone-morphogenetic-protein-2-from-perlecan-domain-i-functionalized-electrospun-poly-%C3%AE%C2%B5-caprolactone-scaffolds-for-bone-regeneration
#20
Yu-Chieh Chiu, Eliza L Fong, Brian J Grindel, Fred K Kasper, Daniel A Harrington, Mary C Farach-Carson
BACKGROUND: Biomaterial scaffolds that deliver growth factors such as recombinant human bone morphogenetic proteins-2 (rhBMP-2) have improved clinical bone tissue engineering by enhancing bone tissue regeneration. This approach could be further improved if the controlled delivery of bioactive rhBMP-2 were sustained throughout the duration of osteogenesis from fibrous scaffolds that provide control over dose and bioactivity of rhBMP-2. In nature, heparan sulfate attached to core proteoglycans serves as the co-receptor that delivers growth factors to support tissue morphogenesis...
December 2016: Journal of Experimental Orthopaedics
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