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Clinical Hypertension

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https://www.readbyqxmd.com/read/27895935/systolic-blood-pressure-values-might-further-risk-stratify-the-adverse-outcomes-of-lvh-in-older-patients-with-chronic-kidney-disease
#1
Carlos R Franco Palacios, Pankaj Goyal, Amanda M Thompson, Brent Deschaine
BACKGROUND: LVH is highly prevalent in patients with CKD and is independently associated with subsequent cardiovascular events. We hypothesized that adding systolic blood pressure values to LVH might differentiate different subgroups of patients at higher risk of cardiovascular events (CVE) and other adverse outcomes. METHODS: Retrospective cohort study of 243 patients older than 60 years with stages 1-5 pre-dialysis CKD. LVH was assessed by electrocardiogram or echocardiogram...
2016: Clinical Hypertension
https://www.readbyqxmd.com/read/27822383/neuronal-nitric-oxide-synthase-in-hypertension-an-update
#2
REVIEW
Yin Hua Zhang
Hypertension is a prevalent condition worldwide and is the key risk factor for fatal cardiovascular complications, such as stroke, sudden cardiac death and heart failure. Reduced bioavailability of nitric oxide (NO) in the endothelium is an important precursor for impaired vasodilation and hypertension. In the heart, NO deficiency deteriorates the adverse consequences of pressure-overload and causes cardiac hypertrophy, fibrosis and myocardial infarction which lead to fatal heart failure and sudden cardiac death...
2016: Clinical Hypertension
https://www.readbyqxmd.com/read/27468357/hypertensive-response-to-exercise-mechanisms-and-clinical-implication
#3
REVIEW
Darae Kim, Jong-Won Ha
A hypertensive response to exercise (HRE) is frequently observed in individuals without hypertension or other cardiovascular disease. However, mechanisms and clinical implication of HRE is not fully elucidated. Endothelial dysfunction and increased stiffness of large artery contribute to development of HRE. From neurohormonal aspects, excess stimulation of sympathetic nervous system and augmented rise of angiotensin II seems to be important mechanism in HRE. Increasing evidences indicates that a HRE is associated with functional and structural abnormalities of left ventricle, especially when accompanied by increased central blood pressure...
2016: Clinical Hypertension
https://www.readbyqxmd.com/read/27413538/prognostic-value-of-systolic-short-term-blood-pressure-variability-in-systolic-heart-failure
#4
Matthieu Berry, Olivier Lairez, Joelle Fourcade, Jérôme Roncalli, Didier Carrié, Atul Pathak, Bernard Chamontin, Michel Galinier
BACKGROUND: Traditional cardiovascular risk factors in the general population are usually correlated to a better prognosis in patients with chronic heart failure (HF). Most of the studies show that blood pressure variability (BPV) has noxious effect on general population but data are missing for patients with systolic HF. The aim of this study was to assess the prognostic impact of short-term blood pressure variability (BPV) in systolic HF. METHODS AND RESULTS: We retrospectively studied 288 patients (60 ± 12 years-old; 79 % male) referred to our tertiary center of HF for the management of their systolic HF (left ventricular ejection fraction was 28 ± 9 %)...
2016: Clinical Hypertension
https://www.readbyqxmd.com/read/27190633/clinical-assessment-of-hypertension-in-children
#5
REVIEW
Nisarg Patel, Nicole Walker
The use of blood pressure measurements have become a routine part of physical exam for the evacuation of cardiovascular health adults and, more recently, children. The most widely used definition of hypertension is delineate as greater than 90 % BP according to age, sex, and height by the National High Blood Pressure Education Program. Current research suggests that pediatric hypertension is influenced by multitude of factors including birth weight, maturity during birth, heredity, and diet leading to primary hypertension...
2016: Clinical Hypertension
https://www.readbyqxmd.com/read/27051525/changes-of-blood-pressure-abdominal-visceral-fat-tissue-and-gene-expressions-in-fetal-programming-induced-rat-model-after-amlodipine-losartan-combination-treatment
#6
Ji Hyen Lee, Hyeryon Lee, Sang Mi Lee, Pil Je Kang, Kwan Chang Kim, Young Mi Hong
BACKGROUND: There are a number of complications that can occur if there is under-nutrition during pregnancy followed by a period of rapid catch-up growth, including a higher chance of adult obesity, insulin resistance and hypertriglyceridemia. The purposes of this study were to investigate the effects of fetal under-nutrition during late pregnancy and lactation on blood pressure, visceral fat tissue, gene expressions and to evaluate changes after amlodipine- losartan combination treatment...
2016: Clinical Hypertension
https://www.readbyqxmd.com/read/26933509/erratum-to-prevalence-of-resistant-hypertension-and-associated-factors-for-blood-pressure-control-status-using-korean-ambulatory-blood-pressure-monitoring-registry-data
#7
Sung Il Choi, Soon Kil Kim, Sungha Park, Ju Han Kim, Sang Hyun Ihm, Gwang-Il Kim, Woo Shik Kim, Wook Bum Pyun, Yu-Mi Kim, Jinho Shin
[This corrects the article DOI: 10.1186/s40885-016-0045-x.].
2016: Clinical Hypertension
https://www.readbyqxmd.com/read/26893942/the-role-of-abnormal-metabolic-conditions-on-arterial-stiffness-in-healthy-subjects-with-no-drug-treatment
#8
Hyo-Sang Hwang, Kwang-Pil Ko, Myeong Gun Kim, Sihun Kim, Jeonggeun Moon, Wook Jin Chung, Mi Seung Shin, Seung Hwan Han
BACKGROUND: Subjects with abnormal metabolic conditions had increased risk for cardiovascular disease. We investigated the role of abnormal metabolic conditions on arterial stiffness in healthy subjects with no drug treatment. METHODS: A total 601 subjects (age 48.7 ± 11.8 years, male 46.2 %, hypertension 19.1 %) were enrolled. Major cardiovascular risk factors, metabolic conditions and parameters (pre-diabetes, diabetes mellitus, metabolic syndrome, fasting blood sugar (FBS), glycated hemoglobin), lipid profiles, hsCRP, and brachial ankle pulse wave velocity (baPWV) were measured...
2016: Clinical Hypertension
https://www.readbyqxmd.com/read/27092268/hypertensive-crisis-in-children-an-experience-in-a-single-tertiary-care-center-in-korea
#9
Geum Hwa Lee, I Re Lee, Se Jin Park, Ji Hong Kim, Ji Young Oh, Jae Il Shin
BACKGROUND: Hypertensive crisis is a medical emergency that can cause acute damage to multiple end-organs. However, relatively little is known on the etiology, treatment, and outcomes of hypertensive crisis in Korean children. The aim of this study was to determine the etiologies and efficacy of drugs for hypertensive crisis in children during the past 5 years at a single center in Korea. METHODS: We analyzed data from 51 children with hypertensive crisis during the period between January 1, 2010 and April 1, 2014...
2015: Clinical Hypertension
https://www.readbyqxmd.com/read/27019747/a-review-on-prescribing-patterns-of-antihypertensive-drugs
#10
REVIEW
Noah Jarari, Narasinga Rao, Jagannadha Rao Peela, Khaled A Ellafi, Srikumar Shakila, Abdul R Said, Nagaraja Kumari Nelapalli, Yupa Min, Kin Darli Tun, Syed Ibrahim Jamallulail, Avinash Kousik Rawal, Ranjani Ramanujam, Ramesh Naidu Yedla, Dhilip Kumar Kandregula, Anuradha Argi, Laxmi Teja Peela
Hypertension continues to be an important public health concern because of its associated morbidity, mortality and economic impact on the society. It is a significant risk factor for cardiovascular, cerebrovascular and renal complications. It has been estimated that by 2025, 1.56 billion individuals will have hypertension. The increasing prevalence of hypertension and the continually increasing expense of its treatment influence the prescribing patterns among physicians and compliance to the treatment by the patients...
2015: Clinical Hypertension
https://www.readbyqxmd.com/read/26973794/the-utility-of-biomarker-risk-prediction-score-in-patients-with-chronic-heart-failure
#11
Alexander E Berezin, Alexander A Kremzer, Yulia V Martovitskaya, Tatyana A Berezina, Tatyana A Samura
BACKGROUND: Chronic heart failure (CHF) has been remained a leading cause of cardiovascular morbidity and mortaluty. The risk stratification of CHF individuals based on clinical criteria and biomarkers' models may improve medical care and probably increase efficacy of treatment strategy. However, various predictive models approved for CHF patients appear to be distinguished in their prognostications. The study aim was to evaluate whether biomarker risk prediction score is powerful tool for risk assessment of three-year fatal and non-fatal cardiovascular events in CHF patients...
2015: Clinical Hypertension
https://www.readbyqxmd.com/read/26929823/impact-of-uncontrolled-hypertension-on-12-month-clinical-outcomes-following-below-the-knee-arteries-btk-interventions-in-patients-with-critical-limb-ischemia
#12
Sung Il Im, Seung-Woon Rha, Byoung Geol Choi, Se Yeon Choi, Jae Joong Lee, Sun Ki Lee, Ji Bak Kim, Jin Oh Na, Cheol Ung Choi, Hong Euy Lim, Jin Won Kim, Eung Ju Kim, Chang Gyu Park, Hong Seog Seo, Dong Joo Oh
BACKGROUND: Despite intensive anti-hypertensive treatment, overall control rates of only 30 ~ 50 % have been reported in patients with hypertension (HTN). However, clinical significance and angiographic characteristics of patients with uncontrolled HTN following Below-the-knee arteries (BTK) interventions in patients with critical limb ischemia (CLI) are not clarified yet as compared to those with controlled HTN. METHODS: A total 165 consecutive hypertensive patients with BTK lesions from August 2004 to November 2012 were enrolled for this study...
2015: Clinical Hypertension
https://www.readbyqxmd.com/read/26900484/association-between-insufficient-medication-of-antihypertensives-and-the-severity-of-acute-ischemic-stroke
#13
Kyung Bok Lee, Jeong-Yoon Lee, Nari Choi, Jee-Eun Yoon, Dong-Won Shin, Ji-Sun Kim, Hakjae Roh, Moo-Young Ahn, Hye-Won Hwang, Min-Su Hyon
BACKGROUND: Although recent studies have suggested that adherence to antihypertensive treatment reduced stroke incidence, the relationship of adherence to antihypertensives with stroke severity has not been studied. This study attempted to know whether nonadherence before stroke is associated with initial severity of acute ischemic stroke. METHODS: Consecutive patients with acute ischemic stroke were identified in Soonchunhyang University Hospital from Mar 2005 to Aug 2014, excluding the cases without hypertension or information of antihypertensive adherence...
2015: Clinical Hypertension
https://www.readbyqxmd.com/read/26895478/erratum-to-spontaneous-rupture-of-a-renal-artery-pseudoaneurysm-in-a-previously-hypertensive-patient
#14
Myung-Sung Kim, Young-Bae Lee, Jae-Hyuk Lee, Chae-Wan Lim, Jun-Hyoung Kim, Hye-Min Choi, Dong-Jin Oh
[This corrects the article DOI: 10.1186/s40885-014-0011-4.].
2015: Clinical Hypertension
https://www.readbyqxmd.com/read/26893941/prevalence-of-resistant-hypertension-and-associated-factors-for-blood-pressure-control-status-with-optimal-medical-therapy-using-korean-ambulatory-blood-pressure-monitoring-registry-data
#15
Sung Il Choi, Soon Kil Kim, Sungha Park, Ju Han Kim, Sang Hyun Ihm, Gwang-Il Kim, Woo Shik Kim, Wook Bum Pyun, Yu-Mi Kim, Jinho Shin
BACKGROUND: Resistant hypertension (RH) may be one of the cause of the plateau in improving the control rate in hypertension (HT) management. The misdiagnosis of RH by clinic blood pressure (BP) is important clinical problem. Aim of the study were to investigate the prevalence of RH by ambulatory blood pressure monitoring (ABPM) and the factor associated with control status of ambulatory BPs. METHODS: For 1230 subjects taking one or more antihypertensive medication (AHM) enrolled in the Korean Ambulatory Blood Pressure Monitoring (Kor-ABP) registry, the prevalence of RH was calculated which was defined as uncontrolled BP by three AHM classes including diuretic or BP in need of four or more AHM classes...
2015: Clinical Hypertension
https://www.readbyqxmd.com/read/26893940/electrocardiogram-derived-qrs-duration-associations-with-elevated-central-aortic-systolic-pressure-casp-in-a-rural-australian-population
#16
Yvonne Yin Leng Lee, Paul Reidler, Herbert Jelinek, Yung Seng Lee, Yuling Zhou, Brett D Hambly, Joel McCabe, Slade Matthews, Honghong Ke, Hassan Assareh, Craig S McLachlan
BACKGROUND: Prolonged electrocardiogram QRS durations are often present in hypertensive patients. Small increases in QRS duration serve as independent risk factors for both increased cardiovascular and all-cause mortality. Aortic stiffness is associated with increases in central aortic systolic blood pressure (CASP). However CASP and ECG QRS duration interactions have not been established in rural community populations. Our aims are to determine if QRS duration > 100 msec is associated with an elevated CASP measure in an Australian rural population...
2015: Clinical Hypertension
https://www.readbyqxmd.com/read/26893939/lifestyle-including-dietary-habits-and-changes-in-coronary-artery-calcium-score-a-retrospective-cohort-study
#17
EunSun Cheong, Jong-Young Lee, Sung Ho Lee, Jin-Ho Kang, Bum-Soo Kim, Byung Jin Kim, Ki-Chul Sung
BACKGROUND: General diet and lifestyle are considered to have an effect on levels of atherosclerosis but previous studies have shown inconsistent results. The aim of this study was to investigate whether macronutrient intake, physical activity and depressive symptoms are associated with progression of preclinical atherosclerosis in healthy Korean adults. METHODS: A total of 2623 individuals from Kangbuk Samsung Hospital Health Screening Center in South Korea were enrolled between 2010 and 2012 and had follow-up at 2013...
2015: Clinical Hypertension
https://www.readbyqxmd.com/read/26893938/prevalence-and-characteristics-of-resistant-hypertension-at-primary-clinics-in-korea-a-nationwide-cross-sectional-study
#18
Kwang No Lee, Jin Oh Na, Cheol Ung Choi, Hong Euy Lim, Jin Won Kim, Eung Ju Kim, Seung-Woon Rha, Hong Seog Seo, Dong Joo Oh, Chang Gyu Park
BACKGROUND: Although resistant hypertension (RH) is known to be associated with higher rates of cardiovascular events than is non-RH, there are no reported data on the prevalence of RH in Korean patients. We evaluated the prevalence and characteristics of RH among hypertensive patients treated at primary clinics in Korea. METHODS: Between August 2010 and January 2011, 247 primary care physicians enrolled 3088 patients with essential hypertension. We acquired demographic and anthropometric data using a questionnaire, evaluated blood pressure, and conducted a variety of laboratory tests using serum and urine...
2015: Clin Hypertens
https://www.readbyqxmd.com/read/26893937/mesoglycan-attenuates-vsmc-proliferation-through-activation-of-amp-activated-protein-kinase-and-mtor
#19
Kyung Young Lee, Dong Hyup Lee, Hyoung Chul Choi
BACKGROUND: Vascular smooth muscle cells (VSMC) proliferation contributes significantly to intimal thickening in atherosclerosis and restenosis diseases. Platelet derived growth factor (PDGF) has been implicated in VSMC proliferation though the activation of multiple growth-promoting signals. Mesoglycan, a natural glycosaminoglycans preparation, is reported to show vascular protective effect. However, the mechanisms by which mesoglycan inhibits proliferation of VSMC are not fully understood...
2015: Clinical Hypertension
https://www.readbyqxmd.com/read/26893936/the-platelet-to-lymphocyte-ratio-reflects-the-severity-of-obstructive-sleep-apnea-syndrome-and-concurrent-hypertension
#20
Yeo-Jeong Song, Jae Hwan Kwon, Joo Yeon Kim, Bo Young Kim, Kyoung Im Cho
BACKGROUND: Chronic intermittent hypoxia, platelet activation and inflammation all play roles in the pathogenesis of obstructive sleep apnea syndrome (OSAS), which may increase the risk of cardiovascular disease (CVD). The aim of this study was to evaluate the relationship of the platelet-to-lymphocyte ratio (PLR) as a new biomarker showing systemic inflammation and platelet distribution width (PDW) as an indicator of platelet activation to the severity of OSAS. METHODS: A total of 290 patients suspected with OSAS who underwent a full night of polysomnography were included...
2015: Clinical Hypertension
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