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Arrhythmia & Electrophysiology Review

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https://www.readbyqxmd.com/read/29977560/second-degree-atrioventricular-block-conceptions-and-misconceptions
#1
REVIEW
Demosthenes G Katritsis
No abstract text is available yet for this article.
June 2018: Arrhythmia & Electrophysiology Review
https://www.readbyqxmd.com/read/29967687/pharmacological-therapy-in-brugada-syndrome
#2
REVIEW
Oholi Tovia Brodie, Yoav Michowitz, Bernard Belhassen
Brugada syndrome (BrS) is a cardiac disease caused by an inherited ion channelopathy associated with a propensity to develop ventricular fibrillation. Implantable cardioverter defibrillator implantation is recommended in BrS, based on the clinical presentation in the presence of diagnostic ECG criteria. Implantable cardioverter defibrillator implantation is not always indicated or sufficient in BrS, and is associated with a high device complication rate. Pharmacological therapy aimed at rebalancing the membrane action potential can prevent arrhythmogenesis in BrS...
June 2018: Arrhythmia & Electrophysiology Review
https://www.readbyqxmd.com/read/29967686/the-cost-of-hybrid-treatment-for-atrial-fibrillation
#3
George Paxinos
No abstract text is available yet for this article.
June 2018: Arrhythmia & Electrophysiology Review
https://www.readbyqxmd.com/read/29967685/premature-ventricular-complex-induced-cardiomyopathy
#4
REVIEW
Jorge G Panizo, Sergio Barra, Greg Mellor, Patrick Heck, Sharad Agarwal
Premature ventricular complex-induced cardiomyopathy is a potentially reversible condition in which left ventricular dysfunction is induced by the occurrence of frequent premature ventricular complexes (PVCs). Various cellular and extracellular mechanisms and risk factors for developing cardiomyopathy in this context have been suggested but the exact pathophysiological mechanism remains unclear. The suppression of PVCs is usually indicated in symptomatic patients with frequent PVCs and also those with left ventricular dysfunction...
June 2018: Arrhythmia & Electrophysiology Review
https://www.readbyqxmd.com/read/29967684/risk-factor-management-in-atrial-fibrillation
#5
REVIEW
Axel Brandes, Marcelle D Smit, Bao Oanh Nguyen, Michiel Rienstra, Isabelle C Van Gelder
Atrial fibrillation (AF) is the most common clinical arrhythmia and is associated with increased morbidity and mortality. There is growing evidence that numerous cardiovascular diseases and risk factors are associated with incident AF and that lone AF is rare. Beyond oral anticoagulant therapy, rate and rhythm control, therapy targeting risk factors and underlying conditions is an emerging AF management strategy that warrants better implementation in clinical practice. This review describes current evidence regarding the association between known modifiable risk factors and underlying conditions and the development and progression of AF...
June 2018: Arrhythmia & Electrophysiology Review
https://www.readbyqxmd.com/read/29967683/sudden-cardiac-death-and-arrhythmias
#6
REVIEW
Neil T Srinivasan, Richard J Schilling
Sudden cardiac death (SCD) and arrhythmia represent a major worldwide public health problem, accounting for 15-20 % of all deaths. Early resuscitation and defibrillation remains the key to survival, yet its implementation and the access to public defibrillators remains poor, resulting in overall poor survival to patients discharged from hospital. Novel approaches employing smart technology may provide the solution to this dilemma. Though the majority of cases are attributable to coronary artery disease, a thorough search for an underlying cause in cases where the diagnosis is unclear is necessary...
June 2018: Arrhythmia & Electrophysiology Review
https://www.readbyqxmd.com/read/29967682/his-bundle-pacing-a-new-frontier-in-the-treatment-of-heart-failure
#7
REVIEW
Nadine Ali, Daniel Keene, Ahran Arnold, Matthew Shun-Shin, Zachary I Whinnett, S M Afzal Sohaib
Biventricular pacing has revolutionised the treatment of heart failure in patients with sinus rhythm and left bundle branch block; however, left ventricular-lead placement is not always technically possible. Furthermore, biventricular pacing does not fully normalise ventricular activation and, therefore, the ventricular resynchronisation is imperfect. Right ventricular pacing for bradycardia may cause or worsen heart failure in some patients by causing dyssynchronous ventricular activation. His bundle pacing activates the ventricles via the native His-Purkinje system, resulting in true physiological pacing, and, therefore, is a promising alternate site for pacing in bradycardia and traditional CRT indications in cases where it can overcome left bundle branch block...
June 2018: Arrhythmia & Electrophysiology Review
https://www.readbyqxmd.com/read/29967681/pacing-for-vasovagal-syncope
#8
REVIEW
Rakesh Gopinathannair, Benjamin C Salgado, Brian Olshansky
Vasovagal syncope (VVS) is due to a common autonomic reflex involving the cardiovascular system. It is associated with bradycardia (cardioinhibitory response) and/or hypotension (vasodepressor response), likely mediated by parasympathetic activation and sympathetic inhibition. While generally a situational, isolated and/or self-limited event, for some, VVS is recurrent, unpredictable and debilitating. Conservative, non-pharmacological management may help, but no specific medical therapy has been proven widely effective...
June 2018: Arrhythmia & Electrophysiology Review
https://www.readbyqxmd.com/read/29967680/treatment-of-atrial-fibrillation-in-patients-with-co-existing-heart-failure-and-reduced-ejection-fraction-time-to-revisit-the-management-guidelines
#9
REVIEW
Alex Baher, Nassir F Marrouche
AF in patients with heart failure and reduced ejection fraction (HFrEF) is common and is associated with an increased risk of stroke, heart failure hospitalisation and all-cause mortality. Rhythm control of AF in this population has been traditionally limited to the use of antiarrhythmic drugs. Clinical trials assessing superiority of pharmacological rhythm control over rate control have been largely disappointing. Catheter ablation has emerged as a viable alternative to pharmacological rhythm control in symptomatic AF and has enjoyed significant technological advancements over the past decade...
June 2018: Arrhythmia & Electrophysiology Review
https://www.readbyqxmd.com/read/29967679/atrial-fibrillation-ablation-in-patients-with-heart-failure-one-size-does-not-fit-all
#10
REVIEW
Rahul K Mukherjee, Steven E Williams, Steven A Niederer, Mark D O'Neill
Atrial fibrillation (AF) is common in patients with heart failure and is associated with poorer clinical outcomes compared with patients with heart failure alone. Recent evidence has challenged previous treatment paradigms in which rate control was considered equivalent to rhythm control in this population. Catheter ablation has emerged as a safe and effective treatment strategy in selected patients and overcomes the issues of limited efficacy and drug toxicities associated with pharmacological rhythm control...
June 2018: Arrhythmia & Electrophysiology Review
https://www.readbyqxmd.com/read/29967678/risk-stratification-in-brugada-syndrome-current-status-and-emerging-approaches
#11
REVIEW
Shohreh Honarbakhsh, Rui Providencia, Pier D Lambiase
Brugada syndrome (BrS) is one of the most common inherited channelopathies associated with an increased risk of sudden cardiac death. Appropriate use of an ICD in high-risk patients is life-saving. However, there remains a lack of consensus on risk stratification, and even on the diagnosis of BrS itself. Some argue that people with a type 1 Brugada ECG pattern but no symptoms should not be diagnosed with BrS, and guidelines recommend observation without therapy in these patients. Others argue that the presence of a spontaneous (rather than drug-induced) type 1 ECG pattern alone is enough to label them as high-risk for arrhythmic events, particularly if syncope is also present...
June 2018: Arrhythmia & Electrophysiology Review
https://www.readbyqxmd.com/read/29967677/pacing-in-vasovagal-syncope
#12
EDITORIAL
Richard Sutton
No abstract text is available yet for this article.
June 2018: Arrhythmia & Electrophysiology Review
https://www.readbyqxmd.com/read/29967676/evolution-of-the-editorial-board-underpins-the-integrity-of-arrhythmia-and-electrophysiology-review
#13
EDITORIAL
Demosthenes G Katritsis
No abstract text is available yet for this article.
June 2018: Arrhythmia & Electrophysiology Review
https://www.readbyqxmd.com/read/29686873/authors-reply-hybrid-approach-for-atrial-fibrillation-ablation-the-jury-is-still-out
#14
Charles M Pearman, Dhiraj Gupta
No abstract text is available yet for this article.
March 2018: Arrhythmia & Electrophysiology Review
https://www.readbyqxmd.com/read/29686872/the-risks-of-electric-currents-at-home
#15
Boghos L Artinian
No abstract text is available yet for this article.
March 2018: Arrhythmia & Electrophysiology Review
https://www.readbyqxmd.com/read/29686871/authors-reply-unravelling-the-mysteries-of-the-human-av-node
#16
Igor R Efimov, Sharon George
No abstract text is available yet for this article.
March 2018: Arrhythmia & Electrophysiology Review
https://www.readbyqxmd.com/read/29686870/practical-techniques-in-cryoballoon-ablation-how-to-isolate-inferior-pulmonary-veins
#17
Shaojie Chen, Boris Schmidt, Stefano Bordignon, Fabrizio Bologna, Takahiko Nagase, Laura Perrotta, K R Julian Chun
Catheter ablation is the most effective treatment option for patients suffering from symptomatic atrial fibrillation. Electrical isolation of the pulmonary veins is the procedural cornerstone. Point-by-point radiofrequency current energy ablation in combination with a 3D electro-anatomical mapping system is the established approach to ablation. In contrast, cryoballoon ablation uses a single-shot approach to facilitate pulmonary vein isolation. However, fixed cryoballoon diameters (28 mm or 23 mm) and non-balloon compliance can lead to technical difficulties in isolating variable pulmonary vein anatomies...
March 2018: Arrhythmia & Electrophysiology Review
https://www.readbyqxmd.com/read/29636976/hybrid-approach-for-atrial-fibrillation-ablation-the-jury-is-still-out
#18
Georgios Giannopoulos, Spyridon Deftereos
No abstract text is available yet for this article.
March 2018: Arrhythmia & Electrophysiology Review
https://www.readbyqxmd.com/read/29636975/unravelling-the-mysteries-of-the-human-av-node
#19
Maria Kokladi
No abstract text is available yet for this article.
March 2018: Arrhythmia & Electrophysiology Review
https://www.readbyqxmd.com/read/29636974/the-significance-of-drug-drug-and-drug-food-interactions-of-oral-anticoagulation
#20
Pascal Vranckx, Marco Valgimigli, Hein Heidbuchel
Vitamin K antagonists (VKAs) such as warfarin are the most commonly prescribed oral anticoagulants worldwide. However, factors affecting the pharmacokinetics of VKAs, such as food and drugs, can cause deviations from their narrow therapeutic window, increasing the bleeding or thrombosis risk and complicating their long-term use. The use of direct oral anticoagulants (DOACs) offers a safer and more convenient alternative to VKAs. However, it is important to be aware that plasma levels of DOACs are affected by drugs that alter the cell efflux transporter P-glycoprotein and/or cytochrome P450...
March 2018: Arrhythmia & Electrophysiology Review
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