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Translational Pediatrics

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https://www.readbyqxmd.com/read/28164037/intestinal-anastomosis-in-children-it-s-time-for-a-general-consensus
#1
Alessandro Boscarelli
No abstract text is available yet for this article.
January 2017: Translational pediatrics
https://www.readbyqxmd.com/read/28164036/primary-extrapulmonary-multidrug-resistant-tuberculosis-in-an-immunocompetent-child-presenting-with-pleural-effusion
#2
Sankalp Yadav, Gautam Rawal
The developing countries are having a number of public health issues. The situation in these resource-limited countries is scary due to the huge burden of infectious diseases like tuberculosis (TB). The latest reports from the WHO shows a high number of drug resistant cases even in the pediatric age groups. Also, the lack of suspicion of drug resistant TB (DR-TB) in the pediatric cases, especially in the absence of a past or family history may lead to delay in diagnosis and flaring-up of the disease. We herein present the very first case of the primary multidrug-resistant TB in an HIV negative child who presented with the left sided pleural effusion...
January 2017: Translational pediatrics
https://www.readbyqxmd.com/read/28164035/proximal-ureteral-atresia-a-rare-congenital-anomaly-incidental-finding-a-case-report
#3
Cosimo Bleve, Maria Luisa Conighi, Lorella Fasoli, Valeria Bucci, Francesco Battaglino, Salvatore Fabio Chiarenza
Ureteral atresia is a rare disease usually associated with a non-functioning dysplastic kidney. The condition may be unilateral or bilateral; focal, short or long and may involve any part of the ureter. Association with other urinary anomalies is rare. We report the case of a 10-month-old boy with prenatal diagnosis of multicystic right kidney. This suspicion was confirmed after birth by ultrasound and static scintigraphy; a right vesicoureteral reflux (VUR) was recorded at cystography. The boy presented a regular renal function but was hospitalized twice for suspected pyelonephritis between the 8th and the 10th month of life and were recorded occasional mild changes in blood pressure...
January 2017: Translational pediatrics
https://www.readbyqxmd.com/read/28164034/surgical-repair-of-tetralogy-of-fallot-the-quest-for-the-ideal-repair
#4
COMMENT
Thierry Bové
No abstract text is available yet for this article.
January 2017: Translational pediatrics
https://www.readbyqxmd.com/read/28164033/aortic-arch-reconstruction-in-norwood-procedure-size-differences-after-hybrid-or-norwood-palliation
#5
COMMENT
Julie Cleuziou
No abstract text is available yet for this article.
January 2017: Translational pediatrics
https://www.readbyqxmd.com/read/28164032/mechanical-circulatory-support-for-the-failing-functional-single-ventricle
#6
COMMENT
John Murala, Ming-Sing Si
No abstract text is available yet for this article.
January 2017: Translational pediatrics
https://www.readbyqxmd.com/read/28164031/postoperative-pulmonary-artery-stenosis-current-options-and-future-directions
#7
COMMENT
David Kalfa
No abstract text is available yet for this article.
January 2017: Translational pediatrics
https://www.readbyqxmd.com/read/28164030/the-dilemma-of-diagnostic-testing-for-prader-willi-syndrome
#8
REVIEW
Arabella Smith, Dorothy Hung
Although Prader-Willi syndrome (PWS) is a well-described clinical dysmorphic syndrome, DNA testing is required for a definitive diagnosis. A definitive diagnosis can be made in approximately 99% of cases using DNA testing; there are a number of DNA tests that can be used for this purpose, although there is no set standard algorithm of testing. The dilemma arises because of the complex genetic mechanisms at the basis of PWS, which need to be elucidated. To establish the molecular mechanism with a complete work up, involves at least 2 tests...
January 2017: Translational pediatrics
https://www.readbyqxmd.com/read/28164029/trends-in-pediatric-echocardiography-and-the-yield-for-congenital-heart-disease-in-a-major-cardiac-referral-hospital-in-cameroon
#9
Clovis Nkoke, Eric Balti, Alain Menanga, Anastase Dzudie, Alain Lekoubou, Samuel Kingue, Andre Pascal Kengne
BACKGROUND: Congenital heart disease (CHD) is a common condition in children in Sub-Saharan Africa (SSA), where it is associated with poor outcomes. Diagnosis of CHD in SSA depends essentially on echocardiography, which is available only in few urban referral centers. Our aim was to assess time changes in the pattern of referral for pediatric echocardiography and the subsequent diagnosis of structural CHD in a major SSA city. METHODS: All pediatric echocardiography performed between 2004 and 2013 at the echocardiography laboratory of the Yaounde General Hospital were reviewed...
January 2017: Translational pediatrics
https://www.readbyqxmd.com/read/28164028/the-clinical-spectrum-of-severe-acute-malnutrition-in-children-in-cameroon-a-hospital-based-study-in-yaounde-cameroon
#10
Andreas Chiabi, Berthe Malangue, Seraphin Nguefack, Félicitée Nguefack Dongmo, Florence Fru, Virginie Takou, Fru Angwafo
BACKGROUND: Severe acute malnutrition (SAM) is a major health problem, and the cause of more than half of childhood deaths in children less than 5 years in developing countries. Globally, 20 million children under 5 years of age are severely malnourished according to the World Health Organization (WHO). In Cameroon, the prevalence of SAM remains high and estimated at 1.9% in 2011 and 1.3% in 2014. The aim of this study was to determine the epidemiology, clinical aspects and outcome of SAM at the Yaounde Gynaeco-Obstetric and Pediatric Hospital (YGOPH)...
January 2017: Translational pediatrics
https://www.readbyqxmd.com/read/28164027/developmental-delay-and-behavioral-disorders-in-59-hiv-exposed-uninfected-infants
#11
Véronique Reliquet, Cécile Brunet-Cartier, Elise Launay, François Raffi
BACKGROUND: Antiretroviral therapy (ART) in HIV pregnant women has led to a dramatic decrease in the rate of HIV mother-to-child transmission but this benefit is counterbalanced with adverse effects related to in utero and neonatal exposure to ART. In 2013, some parents described neurodevelopmental disorders in their children. METHODS: A standardized letter was sent to the 133 women who delivered in Nantes hospital from 01/01/2003 to 31/12/2012 (167 births). RESULTS: Response rate was 33%...
January 2017: Translational pediatrics
https://www.readbyqxmd.com/read/28164026/a-pilot-validation-study-of-crowdsourcing-systematic-reviews-update-of-a-searchable-database-of-pediatric-clinical-trials-of-high-dose-vitamin-d
#12
Nassr Nama, Klevis Iliriani, Meng Yang Xia, Brian P Chen, Linghong Linda Zhou, Supichaya Pojsupap, Coralea Kappel, Katie O'Hearn, Margaret Sampson, Kusum Menon, James Dayre McNally
BACKGROUND: Completing large systematic reviews and maintaining them up to date poses significant challenges. This is mainly due to the toll required of a small group of experts to screen and extract potentially eligible citations. Automated approaches have failed so far in providing an accessible and adaptable tool to the research community. Over the past decade, crowdsourcing has become attractive in the scientific field, and implementing it in citation screening could save the investigative team significant work and decrease the time to publication...
January 2017: Translational pediatrics
https://www.readbyqxmd.com/read/28164025/pulmonary-autograft-in-aortic-position-is-everything-known
#13
COMMENT
Francesco Nappi, Antonio Nenna, Cristiano Spadaccio, Massimo Chello
The Ross operation provides several advantages compared to other valve substitutes to manage aortic valve disease, such as growth potential, excellent hemodynamics, freedom from oral anticoagulation and hemolysis, and better durability. However, progressive dilatation of the pulmonary autografts after Ross operation reflects the inadequate remodeling of the native pulmonary root in the systemic circulation, which results in impaired adaptability to systemic pressure and risk of reoperation after the first decade...
January 2017: Translational pediatrics
https://www.readbyqxmd.com/read/28164024/the-problems-related-with-primary-repair-for-tetralogy-of-fallot-especially-about-transannular-patch-repair
#14
EDITORIAL
Atsushi Mizuno, Koichiro Niwa
No abstract text is available yet for this article.
January 2017: Translational pediatrics
https://www.readbyqxmd.com/read/28164023/repair-of-complete-atrioventricular-septal-defect-with-tetralogy-of-fallot
#15
EDITORIAL
Edvin Prifti
No abstract text is available yet for this article.
January 2017: Translational pediatrics
https://www.readbyqxmd.com/read/27867857/training-for-mis-in-pediatric-urology-proposition-of-a-structured-training-curriculum
#16
REVIEW
Maria Escolino, Francesco Turrà, Alessandro Settimi, Ciro Esposito
In Europe there are a lot of training centers for minimally invasive surgery (MIS) but a standardized MIS training program in pediatric urology doesn't exist at the moment. We performed a literature review with the last goals to propose a structured training curriculum in MIS urology for pediatric surgeons. Pediatric urologists have to obtain a valid MIS training curriculum completing the following 4 steps: (I) Theoretical part (theoretical courses, masterclass) to acquire theoretical knowledge; (II) experimental training (simulation on pelvic trainer, virtual reality simulators, animal models, 3-D ex-vivo models) to acquire basic laparoscopic skills; (III) stages in European centers of reference for pediatric MIS urology to learn all surgery aspects; (IV) personal operative experience...
October 2016: Translational pediatrics
https://www.readbyqxmd.com/read/27867856/minimally-invasive-surgery-in-management-of-renal-tumours-in-children
#17
REVIEW
Kathrine Olaussen Eriksen, Navroop Singh Johal, Imran Mushtaq
Minimally invasive surgery (MIS) in the management of malignant and benign renal tumours in children is gradually becoming more common. Experience is limited and restricted to case reports, retrospective chart reviews and a few cohort studies. There are currently no randomized controlled trials or controlled clinical trials comparing the laparoscopic and open surgical approach for the management of renal tumours in children. MIS may offer the same oncologic outcome in malignant renal tumours whilst providing the advantages associated with MIS in correctly selected cases...
October 2016: Translational pediatrics
https://www.readbyqxmd.com/read/27867855/laparoscopic-approach-for-gonadectomy-in-pediatric-patients-with-intersex-disorders
#18
REVIEW
Andres Calvo, Maria Escolino, Alessandro Settimi, Agnese Roberti, Maria Grazia Caprio, Ciro Esposito
The birth of a child with a disorder of sex development (DSD) prompts a long-term management strategy that involves a myriad of professionals working with the family. There has been progress in diagnosis, surgical techniques and in understanding psychosocial issues related to this condition. However, since these kinds of disorders are rare and have many anatomical variations, individual care is necessary, especially regarding surgical management. Gonadectomy is indicated in a number of intersex disorders with a Y chromosome to reduce the associated risk of cancer...
October 2016: Translational pediatrics
https://www.readbyqxmd.com/read/27867854/laparoscopic-extravesical-ureteral-reimplantation-levur-a-systematic-review
#19
REVIEW
Alessandra Farina, Ciro Esposito, Maria Escolino, Manuel Lopez, Alessandro Settimi, François Varlet
BACKGROUND: Laparoscopic ureteral reimplantation is a feasible method for treating ureteral pathology with good preliminary results in the literature. In this study, we review medium term results for laparoscopic ureteral reimplantation and discuss current developments of this procedure. METHODS: Medline and Embase databases were searched using relevant key terms to identify reports of paediatric laparoscopic extravesical ureteral reimplantation (LEVUR). Literature reviews, case reports, series of <3 children and adult studies (age >20 years) were excluded...
October 2016: Translational pediatrics
https://www.readbyqxmd.com/read/27867853/treatment-of-vesico-ureteral-reflux-in-infants-and-children-using-endoscopic-approaches
#20
REVIEW
Manabu Okawada, Ciro Esposito, Maria Escolino, Alessandra Farina, Mariapina Cerulo, Francesco Turrà, Atsuyuki Yamataka
Vesicoureteral reflux (VUR) represents one of the most significant risk factors for acute pyelonephritis in children. Endoscopic treatment of VUR dates back to 1981 when Matouschek first described injection of the ureteral orifice in an attempt to correct VUR. In addition, also Politano and colleagues and McDonald described successful correction of reflux using endoscopic techniques. After these reports subureteral Teflon injection (STING) came to be appreciated as a viable new way to less invasively correct one of the most common pediatric urologic problems...
October 2016: Translational pediatrics
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