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HLA

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https://www.readbyqxmd.com/read/27925411/a-novel-hla-allele-hla-b-50-48-identified-by-sequencing-based-typing
#1
T F K Gama, R A Fabreti-Oliveira, P A M Souza, E Nascimento
The HLA-B*50:48 allele differs from HLA-B*50:01:01 by one nucleotide substitution at position 130.
December 7, 2016: HLA
https://www.readbyqxmd.com/read/27910249/the-hla-a-b-and-drb1-polymorphism-in-a-large-dataset-of-south-brazil-bone-marrow-donors-from-rio-grande-do-sul
#2
J A Boquett, J M Nunes, S Buhler, M Z de Oliveira, L F Jobim, M Jobim, N J R Fagundes, L Schüler-Faccini, A Sanchez-Mazas
Human leukocyte antigen (HLA) genes are very informative in population genetics studies and their variability has been widely used to reconstruct the history of geographic and/or demographic expansions of human populations. The characterization of HLA diversity at the population level is also fundamental in clinical studies, particularly for bone marrow transplantation programs. In this study, we investigated the HLA molecular variation in Rio Grande do Sul, South Brazil, in order to identify possible regional differences across this state...
December 2, 2016: HLA
https://www.readbyqxmd.com/read/27891821/detection-of-hla-c-04-247-a-novel-hla-c-04-variant-in-a-taiwanese-hematopoietic-stem-cell-donor
#3
K L Yang, P Y Lin
One nucleotide replacement at residue 511 of the HLA-C*04:01:01:01 results in a novel allele, HLA-C*04:247.
November 27, 2016: HLA
https://www.readbyqxmd.com/read/27891765/hla-b-13-95-a-novel-variant-of-hla-b-13-discovered-in-a-taiwanese-blood-donor
#4
K L Yang, P Y Lin
A single nucleotide replacement at residue 430 of HLA-B*13:01:01 results in a new allele, HLA-B*13:95.
November 27, 2016: HLA
https://www.readbyqxmd.com/read/27885833/identification-of-the-novel-hla-drb1-08-69-allele-by-polymerase-chain-reaction-sequence-based-typing-in-a-chinese-cord-blood-donor
#5
L-N Dong, Z-D Han, W Zhang, J He, F-M Zhu
HLA-DRB1*08:69 has one nucleotide change from HLA-DRB1*08:03:02 at position 262 G>A.
November 24, 2016: HLA
https://www.readbyqxmd.com/read/27878985/hla-a-30-99-shows-a-new-amino-acid-position-156-within-hla-a-30-subtypes
#6
A Balas, F Sánchez-Gordo, J M Gomez-Zumaquero, J L Vicario
A novel HLA-A*30:99 allele was characterized in a Spanish individual.
November 22, 2016: HLA
https://www.readbyqxmd.com/read/27878982/hla-dqb1-03-01-34-a-novel-allele-which-has-arisen-by-silent-mutation-in-codon-87
#7
D Zhou, S-Z Jin, H-Y Zou
HLA-DQB1*03:01:34 has one nucleotide change from HLA- DQB1*03:01:01 at nucleotide 357 bp where C>A in exon 2.
November 22, 2016: HLA
https://www.readbyqxmd.com/read/27860421/a-novel-allele-hla-drb1-12-60n-detected-in-a-taiwanese-unrelated-hematopoietic-stem-cell-donor
#8
K L Yang, P Y Lin
One nucleotide deletion at residue 157 of HLA-DRB1*12:02:01 results in a new allele, HLA-DRB1*12:60N.
November 17, 2016: HLA
https://www.readbyqxmd.com/read/27860403/discovery-of-hla-b-51-209-a-novel-hla-b-51-variant-in-a-taiwanese-individual
#9
K L Yang, P Y Lin
One nucleotide substitution at residue 85 of HLA-B*51:01:01:01 results in a novel allele, HLA-B*51:209.
November 17, 2016: HLA
https://www.readbyqxmd.com/read/27863161/hla-dr-polymorphisms-influence-in-vivo-responses-to-staphylococcal-toxic-shock-syndrome-toxin-1-in-a-transgenic-mouse-model
#10
A Krogman, A Tilahun, C S David, V R Chowdhary, M P Alexander, G Rajagopalan
Toxic shock syndrome toxin-1 (TSST-1) is a potent superantigen produced by Staphylococcus aureus. In addition to menstrual and nonmenstrual toxic shock syndromes, TSST-1 is also implicated in the immunopathogenesis of pneumonia, infective endocarditis, neonatal exanthematous disease, and atopic dermatitis among others. Superantigens first bind to major histocompatibility complex (MHC) class II molecules and then activate a large proportion of T cells by cross-linking their T cell receptor. As binding to MHC class II molecules is a critical step in the robust activation of the immune system by TSST-1 and other superantigens, polymorphic variations between different HLA-DR alleles could potentially influence the magnitude of immune activation and immunopathology caused by TSST-1...
November 15, 2016: HLA
https://www.readbyqxmd.com/read/27863148/identification-of-dpb1-581-01-a-novel-hla-dpb1-allele-in-a-chinese-mongolian-individual
#11
S Liu, X Xu, M Sun, Y Yao, L Shi
HLA-DPB1*581:01 differs from DPB1*41:01:01 at codon 57, substituting codon GAG for GAC in exon 2.
November 15, 2016: HLA
https://www.readbyqxmd.com/read/27863124/a-novel-hla-b-18-allele-hla-b-18-124-identified-in-a-german-volunteer-bone-marrow-donor
#12
A M E Sidahmed, T Mohamed, L Stamm, F Khan, N Berka
HLA-B*18:124 differs from B*18:01:01:02 by a single substitution in exon 4.
November 15, 2016: HLA
https://www.readbyqxmd.com/read/27807936/diversity-of-killer-cell-immunoglobulin-like-receptor-genes-in-drung-chinese
#13
L Jiang, P Su, T Yang, X Zhu, F Yao, Z Che, H Ma, J Wang, Q Chen
Killer cell immunoglobulin-like receptor (KIR) genes are variably distributed among populations from distinct geographic areas and ethnic origins. We describe, for the first time, KIR gene diversity in 152 unrelated and healthy Drung individuals, as measured by sequence-specific polymerase chain reaction. All 16 known KIR genes were detected. Of these, the framework genes KIR2DL4, 3DL2, 3DL3, and 3DP1 were present in all individuals as expected, along with the non-framework genes KIR2DL1, 2DL3, and 2DP1. In contrast, KIR2DL2, 2DS2, and 2DS5 were unusually rare, suggesting that KIR gene distribution was relatively concentrated...
November 2, 2016: HLA
https://www.readbyqxmd.com/read/27870488/nomenclature-for-factors-of-the-hla-system-update-september-2016
#14
Steven G E Marsh
No abstract text is available yet for this article.
December 2016: HLA
https://www.readbyqxmd.com/read/27870487/identification-of-a-novel-hla-c-06-variant-allele-hla-c-06-166-by-sequence-based-typing-in-a-chinese-individual
#15
J Wang, Y Zhang, Q Li, K Ru, X Wang
HLA-C*06:166 differs from HLA-C*06:02:01:01 (146T → C, exon 2, V25A).
December 2016: HLA
https://www.readbyqxmd.com/read/27870486/nomenclature-for-factors-of-the-hla-system-update-july-2016
#16
Steven G E Marsh
No abstract text is available yet for this article.
December 2016: HLA
https://www.readbyqxmd.com/read/27870485/nomenclature-for-factors-of-the-hla-system-update-august-2016
#17
Steven G E Marsh
No abstract text is available yet for this article.
December 2016: HLA
https://www.readbyqxmd.com/read/27807949/identification-of-the-novel-hla-b-39-01-23-allele-by-polymerase-chain-reaction-sequence-based-typing
#18
Y-M He, L-N Dong, N-Y Chen, J He, F-M Zhu
HLA-B*39:01:23 differs from HLA-B*39:01:01 by a single nucleotide substitution at position 153 C > T.
December 2016: HLA
https://www.readbyqxmd.com/read/27807939/a-frame-shift-due-to-a-two-nucleotide-insertion-results-in-the-an-hla-b-null-allele-b-39-97n
#19
W Wang, W Zhang, J He, J Xu, F-M Zhu
HLA-B*39:97N differs from HLA-B*39:01:01 by a two nucleotide insertion at position 604-605.
December 2016: HLA
https://www.readbyqxmd.com/read/27804253/identification-of-two-novel-hla-dqb1-alleles-hla-dqb1-03-164-and-hla-dqb1-03-165-in-chinese-individuals
#20
L-N Dong, J-J He, W Zhang, J He, F-M Zhu
HLA-DQB1*03:164 shows 604G>T and HLA-DQB1*03:165 has 611 C>G change compared with HLA-DQB1*03:01:01:01.
December 2016: HLA
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