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HLA

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https://www.readbyqxmd.com/read/30003693/identification-of-a-novel-hla-dqb1-allele-dqb1-06-111-by-sequence-based-typing-in-a-taiwanese-individual
#1
C L Chang, C Y Lin
HLA-DQB1*06:111 differs from HLA-DQB1*06:02:01 by the single nucleotide substitution resulting in one amino acid change. This article is protected by copyright. All rights reserved.
July 12, 2018: HLA
https://www.readbyqxmd.com/read/30003685/genomic-full-length-sequence-of-hla-b-15-178-was-identified-by-full-length-group-specific-sequencing
#2
Liu-Mei He, Hui Yang, Yun-Ping Xu, Wen-Xu Hong
Genomic full length sequence of HLA-B*15:178 was identified by a group-specific sequencingapproach from China. This article is protected by copyright. All rights reserved.
July 12, 2018: HLA
https://www.readbyqxmd.com/read/30003680/the-hla-b-46-67-allele-identified-in-a-volunteer-donor-for-hematopoietic-stem-cell-transplant
#3
In-Cheol Baek, Eun-Jeong Choi, Dong-Hwan Shin, Hyoung-Jae Kim, Tai-Gyu Kim
HLA-B*46:67 differs from HLA-B*46:01:01 in codons 94, 95 and 103 in exon 3. This article is protected by copyright. All rights reserved.
July 12, 2018: HLA
https://www.readbyqxmd.com/read/29992771/identification-of-the-novel-hla-a-32-01-01-08-allele-in-a-saudi-individual
#4
F Aloufi, M Gattan, H Alanazi, A Alqasem, A H Hajeer
HLA-A*32:01:01:08 differs from HLA-A*32:01:01:01 by a single nucleotide substitution (G➔A) at position 2200. This article is protected by copyright. All rights reserved.
July 10, 2018: HLA
https://www.readbyqxmd.com/read/29989330/genomic-full-length-sequence-of-hla-a-11-172-was-identified-by-full-length-group-specific-sequencing
#5
Yun-Ping Xu, Hui Yang, Wen-Xu Hong
Genomic full length sequence of HLA-A*11:172 was identified by a group-specific sequencing approach from China. This article is protected by copyright. All rights reserved.
July 10, 2018: HLA
https://www.readbyqxmd.com/read/29962081/identification-of-an-hla-a-null-allele-hla-a-33-129n
#6
Y Yin, P Takemura, E F Reed, Q Zhang
HLA-A*33:129N has a single nucleotide insertion compared with its closest allele HLA-A*33:01:01 at codon 186. This article is protected by copyright. All rights reserved.
July 2, 2018: HLA
https://www.readbyqxmd.com/read/29962028/a-novel-hla-a-null-allele-hla-a-66-28n
#7
Y Yin, P Takemura, E F Reed, Q Zhang
The novel HLA-A*66:28N allele differs from HLA-A*66:03 by a single nucleotide deletion at codon 185. This article is protected by copyright. All rights reserved.
July 2, 2018: HLA
https://www.readbyqxmd.com/read/29962113/case-report-a-transplant-candidate-with-unexpected-serum-reactivity-against-the-45ke-eplet-on-hla-b-alleles
#8
B Cauquil, G Dautin, R J Duquesnoy
This case report describes the serum antibody specificity against the 45KE eplet which had not been yet shown to be antibody-verified. This antibody was produced by a 41-year old European male with Berger's disease. His serum had HLA class I antibody reactivity as determined in IgG binding assays with single allele panels (OneLambda, ThermoFisher, Lot 8 and Lot 9). The HLAMatchmaker analysis revealed reproducible serum reactivity only with alleles carrying the 45KE eplet. The cause of this 45KE-specific immunization is unknown because this male patient had never been transfused nor received a previous transplant, Moreover, his mother's HLA type did not have any 45KE-carrying allele...
July 1, 2018: HLA
https://www.readbyqxmd.com/read/29962021/six-novel-hla-b-drb1-and-dqb1-alleles-identified-in-brazilian-individuals
#9
R A Fabreti-Oliveira, S G E Marsh, M F Lasmar, E Nascimento
The novel HLA alleles B*40:331, B*40:343, B*42:24, DRB1*01:74, DQB1*03:243, DQB1*03:02:20 were identified in Brazilian individuals. This article is protected by copyright. All rights reserved.
July 1, 2018: HLA
https://www.readbyqxmd.com/read/29961967/identification-of-seven-novel-hla-class-i-and-ii-alleles
#10
S Ferrari-Lacraz, D Masson, J Villard, S Buhler
Seven novel alleles were identified using two next generation sequencing technologies. Three alleles were confirmed. This article is protected by copyright. All rights reserved.
July 1, 2018: HLA
https://www.readbyqxmd.com/read/29959830/the-distribution-of-hla-drb3-alleles-among-hla-drb1-03-01-positive-haplotypes
#11
K S Jankovic, Z Grubic, J Jakupic, M B Kamenaric, M Maskalan, R Zunec
HLA-DRB3 allelic polymorphism on HLA-DRB1*03:01-positive haplotypes was investigated among 104 cadaveric donors typed for HLA-A, -B, -DRB1, and -DRB3. Only HLA-DRB3*01:01:02 and -DRB3*02:02:01:01 alleles were detected among HLA-DRB1*03:01-positive individuals and their distribution depended on HLA-B*08 presence: nearly all HLA-B*08-positive samples carried DRB3*01:01:02, while HLA-DRB3*02:02:01:01 was more frequent among HLA-B*08-negative subjects. This article is protected by copyright. All rights reserved...
June 30, 2018: HLA
https://www.readbyqxmd.com/read/29943500/activating-kir-haplotype-influences-clinical-outcome-following-hla-matched-sibling-hematopoietic-stem-cell-transplantation
#12
S L Heatley, C G Mullighan, K Doherty, S Danner, G M O'Connor, U Hahn, J Szer, A Schwarer, K Bradstock, L C Sullivan, P G Bardy, A G Brooks
Natural killer cells are thought to influence the outcome of hematopoietic stem cell transplant (HSCT), impacting on relapse, overall survival, graft versus host disease and the control of infection, in part through the complex interplay between the large and genetically diverse killer immunoglobulin-like receptor (KIR) family and their ligands. This study examined the relationship between KIR gene content and clinical outcomes including the control of opportunistic infections such as cytomegalovirus in the setting of human leucocyte antigen (HLA)-matched sibling HSCT in an Australian cohort...
June 25, 2018: HLA
https://www.readbyqxmd.com/read/29935012/urdu-speaking-population-from-south-india
#13
V Seshasubramanian, N K Manisekar, A D Sathishkannan, C Naganathan, Y Nandakumar, S Narayan
A total of 397 (70 bone marrow and 327 cord blood donors) Urdu speaking individuals from Deccan plateau of India from the states of Andhra Pradesh, Telangana, Tamilnadu and Karnataka were typed for HLA A, B, C, DRB and DQB alleles. Out of 397 samples, 361 samples were typed by Sanger sequencing using SeCore Sequencing IVD® kit user protocol (Invitrogen) and the results detected on an automated ABI 3730xl DNA analyzer instrument. This article is protected by copyright. All rights reserved.
June 22, 2018: HLA
https://www.readbyqxmd.com/read/29935005/kannadigas-from-south-india
#14
V Seshasubramanian, N K Manisekar, A D Sathishkannan, C Naganathan, Y Nandakumar, S Narayan
A total of 174 (48 bone marrow and 126 cord blood donors) Kannada speaking individuals (Kannadigas) from Karnataka, Tamilnadu and Telangana were typed for HLA A, B, C, DRB and DQB alleles. Out of 174 samples, 146 samples were typed by Sanger sequencing using SeCore Sequencing IVD® kit user protocol (Invitrogen) and the results detected on an automated ABI 3730xl DNA analyzer instrument. The sequencing data was analyzed using uTYPE® 7.1. The other 28 samples were typed by NGS Illumina MiniSeq Platform using MIA FORA NGS FLEX HLA Typing Kit...
June 22, 2018: HLA
https://www.readbyqxmd.com/read/29934983/genetic-polymorphism-analysis-of-micb-gene-in-jing-ethnic-minority-of-southern-china
#15
X Liu, X Chen, X Wei, Y Meng, L Liu, S Dai
In the present study, the polymorphism in the 5'-upstream regulation region (5'-URR), coding region (exons 2-4), and the 3'-untranslated region (3'-UTR) of MICB gene were investigated for 150 healthy unrelated Jing individuals in Guangxi Zhuang Autonomous Region, by using PCR-SBT method. A total of 14 variation sites in the 5'-URR, 9 in coding region, and 6 in the 3'-UTR were detected in the Jing population. The MICB gene seems to present two different lineages showing functional variations mainly in nucleotides of the promoter region...
June 22, 2018: HLA
https://www.readbyqxmd.com/read/29920977/identification-of-a-novel-hla-a-02-allele-hla-a-02-01-01-32-in-a-deceased-caucasoid-donor
#16
J B Sherrill, T R Turner, J P Abraham, C S Ho
HLA-A*02:01:01:32 differs from HLA-A*02:01:01:01 by a single nucleotide substitution (G➔A) at position 2456. This article is protected by copyright. All rights reserved.
June 19, 2018: HLA
https://www.readbyqxmd.com/read/29920973/the-hla-b-54-35-and-b-54-38-identified-in-volunteer-donors-for-hematopoietic-stem-cell-transplant
#17
I-C Baek, E-J Choi, D-H Shin, H-J Kim, T-G Kim
HLA-B*54:35 and -B*54:38 differ from HLA-B*54:01:01 in codons in exons 2 and 3 This article is protected by copyright. All rights reserved.
June 19, 2018: HLA
https://www.readbyqxmd.com/read/29896792/identification-of-a-new-hla-a-11-allele-a-11-251n
#18
S-K Kim, J Im, C E Yoon, H B Oh
The new allele, A*11:251N, differs from A*11:01:01 by insertion of two nucleotide at position 204-205. This article is protected by copyright. All rights reserved.
June 12, 2018: HLA
https://www.readbyqxmd.com/read/29896767/identification-of-hla-b-15-296-by-next-generation-sequencing-technology-in-a-chinese-han-individual
#19
Z-R Quan, X-X Zhong, S-Q Gao
HLA-B*15:296 differs from HLA-B*15:01:01:01 in exon 3 by a single nucleotide. This article is protected by copyright. All rights reserved.
June 12, 2018: HLA
https://www.readbyqxmd.com/read/29888557/persistence-of-de-novo-donor-specific-hla-antibodies-after-lung-transplantation-a-potential-marker-of-decreased-patient-survival
#20
M Schmitzer, H Winter, N Kneidinger, G Meimarakis, A Dick, R Schramm, L V Klotz, G Preissler, N Strobl, V von Dossow, C Schneider, T Weig, R Hatz, T Kauke
The impact of de novo donor-specific anti-HLA antibodies (DSA) on outcomes in lung transplantation is still a matter of debate. We hypothesize that differentiating DSA by persistent and transient appearance may offer an additional risk assessment. The clinical relevance of HLA-antibodies was investigated prospectively in 72 recipients with a median follow-up period of 21 months. The presence of HLA-antibodies was analysed by single antigen bead assay prior to and after (3 weeks, 3, 6, 12 and 18 months) transplantation...
June 10, 2018: HLA
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