journal
MENU ▼
Read by QxMD icon Read
search

Bladder Cancer

journal
https://www.readbyqxmd.com/read/29732395/psychological-stress-and-suicide-in-bladder-cancer-patients
#1
Edward M Messing
No abstract text is available yet for this article.
April 26, 2018: Bladder Cancer
https://www.readbyqxmd.com/read/29732394/challenging-cases-in-urothelial-cancer
#2
Mark S Soloway
No abstract text is available yet for this article.
April 26, 2018: Bladder Cancer
https://www.readbyqxmd.com/read/29732393/real-world-effectiveness-of-chemotherapy-in-elderly-patients-with-metastatic-bladder-cancer-in-the-united-states
#3
Matthew D Galsky, Sumanta Kumar Pal, Shih-Wen Lin, Sarika Ogale, Marko Zivkovic, Joseph Simpson, Christina Derleth, Christina Schiff, Guru Sonpavde
Background: Outcomes for patients with metastatic bladder cancer (mBC) are generally poor and progressively worse following first-line (1L) chemotherapy. Objective: To evaluate treatment patterns, survival outcomes, and characteristics of a large, real-world US population of elderly patients with advanced mBC receiving 1L and second-line (2L) treatment retrospectively. Methods: We identified patients with advanced mBC (aged ≥66 years)-newly diagnosed between January 1, 2004, and December 31, 2011-in the National Cancer Institute Surveillance, Epidemiology, and End Results (SEER) Program-Medicare linked database and assessed their palliative systemic chemotherapy treatments and survival outcomes...
April 26, 2018: Bladder Cancer
https://www.readbyqxmd.com/read/29732392/bladder-cancer-genetic-susceptibility-a-systematic-review
#4
Evangelina López de Maturana, Marta Rava, Chiaka Anumudu, Olga Sáez, Dolores Alonso, Núria Malats
Background: The variant/gene candidate approach to explore bladder cancer (BC) genetic susceptibility has been applied in many studies with significant findings reported. However, results are not always conclusive due to the lack of replication by subsequent studies. Objectives: To identify all epidemiological investigations on the genetic associations with BC risk, to quantify the likely magnitude of the associations by applying metaanalysis methodology and to assess whether there is a potential for publication/reporting bias...
April 26, 2018: Bladder Cancer
https://www.readbyqxmd.com/read/29732391/the-role-of-adjuvant-radiation-therapy-in-locally-advanced-bladder-cancer
#5
Gary D Lewis, Waqar Haque, Vivek Verma, E Brian Butler, Bin S Teh
Background: The standard of care for locally advanced bladder cancer (LABC) is neoadjuvant chemotherapy followed by cystectomy. However, the role of adjuvant therapy for locally advanced bladder cancer is unclear. Objective: The purpose of this study was to evaluate the outcomes of adjuvant radiation therapy (RT) for patients with LABC, and to determine which risk factors best predict for patients who may best benefit from adjuvant RT. Methods: The National Cancer Data Base (NCDB) was queried (2004- 2013) for patients with newly-diagnosed pT3-4N0-3M0 urothelial carcinoma of the bladder that received neoadjuvant chemotherapy and cystectomy...
April 26, 2018: Bladder Cancer
https://www.readbyqxmd.com/read/29732390/prognostication-in-patients-treated-with-radical-cystectomy-for-urothelial-bladder-carcinoma-a-new-simplified-model-incorporating-histological-variants
#6
Ja Hyeon Ku, Hyeong Dong Yuk, Guiherme Godoy, Gilard E Amiel, Seth P Lerner
Purpose: The aim of this study was to evaluate the clinical significance of histological variants (HV) and to develop a new and simple prediction model incorporating variant forms in patients who underwent radical cystectomy for urothelial carcinoma (UC). Materials and methods: We analyzed the data of 365 patients. We evaluated whether HV were independent predictors of survival. A new scoring model was developed using the regression coefficients from the multivariate Cox proportional hazard model...
April 26, 2018: Bladder Cancer
https://www.readbyqxmd.com/read/29732389/the-prognostic-role-of-the-change-in-neutrophil-to-lymphocyte-ratio-during-neoadjuvant-chemotherapy-in-patients-with-muscle-invasive-bladder-cancer-a-retrospective-multi-institutional-study
#7
Jeenan Kaiser, Haocheng Li, Scott A North, Raya Leibowitz-Amit, Jo-An Seah, Nisha Morshed, Caroline Chau, Richard Lee-Ying, Daniel Y C Heng, Srikala Sridhar, Simon J Crabb, Nimira S Alimohamed
Background: The impact of the change in the neutrophil-to-lymphocyte ratio (NLR) during neoadjuvant chemotherapy (NAC) on outcomes in patients with muscle-invasive bladder cancer (MIBC) is poorly understood. Objective: To evaluate the prognostic impact of the change in NLR during NAC for patients with MIBC. Methods: Patients referred to academic, community, and quaternary referral centres in Alberta, Canada from 2005 to 2015, Ontario, Canada from 2005 to 2013, and Southampton, UK from 2004 to 2010 were evaluated...
April 26, 2018: Bladder Cancer
https://www.readbyqxmd.com/read/29732388/systematic-review-characteristics-and-preclinical-uses-of-bladder-cancer-cell-lines
#8
Tahlita C M Zuiverloon, Florus C de Jong, James C Costello, Dan Theodorescu
Background: Bladder cancer (BC) cell lines are indispensable in basic and preclinical research. Currently, an up-to-date and comprehensive overview of available BC cell lines is not available. Objective: To provide an overview and resources on the origin, pathological and molecular characteristics of commonly used human, murine and canine BC cell lines. Methods: A PubMed search was performed for relevant articles published between 1980 and 2017 according to the following MeSH terms: cell line; cell line, tumor; urinary bladder neoplasms; carcinoma, transitional cell...
April 26, 2018: Bladder Cancer
https://www.readbyqxmd.com/read/29732387/transversus-abdominis-plane-blockade-as-part-of-a-multimodal-postoperative-analgesia-plan-in-patients-undergoing-radical-cystectomy
#9
Richard S Matulewicz, Mehul Patel, Brian J Jordan, Jacqueline Morano, Brendan Frainey, Yasin Bhanji, Mahreen Bux, Antoun Nader, Shilajit D Kundu, Joshua J Meeks
Background: Radical cystectomy (RC) is a morbid procedure with frequent complications that may benefit from implementation of an enhanced recovery after surgery (ERAS) protocol. Objective: To examine the benefits of a multimodal analgesic plan that uses continuous transversus abdominis plane (TAP) blockade as part of an ERAS protocol after RC. Methods: A retrospective comparison of consecutive patients undergoing RC over a 4-year period was conducted...
April 26, 2018: Bladder Cancer
https://www.readbyqxmd.com/read/29732386/naturally-occurring-canine-invasive-urothelial-carcinoma-a-model-for-emerging-therapies
#10
REVIEW
Breann C Sommer, Deepika Dhawan, Timothy L Ratliff, Deborah W Knapp
The development of targeted therapies and the resurgence of immunotherapy offer enormous potential to dramatically improve the outlook for patients with invasive urothelial carcinoma (InvUC). Optimization of these therapies, however, is crucial as only a minority of patients achieve dramatic remission, and toxicities are common. With the complexities of the therapies, and the growing list of possible drug combinations to test, highly relevant animal models are needed to assess and select the most promising approaches to carry forward into human trials...
April 26, 2018: Bladder Cancer
https://www.readbyqxmd.com/read/29732385/thromboembolism-in-patients-with-bladder-cancer-incidence-risk-factors-and-prevention
#11
REVIEW
Piotr Zareba, Wilhelmina C M Duivenvoorden, Jehonathan H Pinthus
Patients with bladder cancer are at high risk of developing both venous and arterial thromboembolic events. Factors that contribute to this phenomenon include the hypercoagulable state induced by the malignancy itself, medical comorbidities that are common in this predominantly elderly patient population as well as treatments such as prolonged pelvic surgery and cisplatin-based chemotherapy. While formal guidelines address prevention of venous thromboembolism in patients undergoing radical cystectomy, consensus regarding the role of pharmacologic prophylaxis in patients with bladder cancer being treated with chemotherapy, either with neoadjuvant or adjuvant intent in conjunction with radical cystectomy, as part of bladder preservation protocols or for metastatic disease, has proved elusive...
April 26, 2018: Bladder Cancer
https://www.readbyqxmd.com/read/29430515/clinical-trials-corner
#12
Piyush K Agarwal, Cora N Sternberg
No abstract text is available yet for this article.
January 20, 2018: Bladder Cancer
https://www.readbyqxmd.com/read/29430514/molecular-landscape-of-non-muscle-invasive-bladder-cancer
#13
Edward M Messing
No abstract text is available yet for this article.
January 20, 2018: Bladder Cancer
https://www.readbyqxmd.com/read/29430513/challenging-cases-in-urothelial-cancer
#14
Mark S Soloway
No abstract text is available yet for this article.
January 20, 2018: Bladder Cancer
https://www.readbyqxmd.com/read/29430512/defining-priorities-to-improve-patient-experience-in-non-muscle-invasive-bladder-cancer
#15
Tullika Garg, Jill Nault Connors, Ilene G Ladd, Tyler L Bogaczyk, Sharon L Larson
Background: Although approximately 75% of bladder cancers are non-muscle invasive (NMIBC) at diagnosis, most research tends to focus on invasive disease (e.g., experiences related to radical cystectomy and urinary diversion). There is a lack of studies on quality of life, and especially qualitative research, in bladder cancer generally. As a result, relatively little is known about the experiences and needs of NMIBC patients. Objective: To understand patient experience, define care priorities, and identify targets for care improvement in NMIBC across the cancer continuum...
January 20, 2018: Bladder Cancer
https://www.readbyqxmd.com/read/29430511/disparities-in-the-use-of-continent-urinary-diversions-after-radical-cystectomy-for-bladder-cancer
#16
Nicholas J Farber, Izak Faiena, Viktor Dombrovskiy, Alexandra L Tabakin, Brian Shinder, Rutveej Patel, Sammy E Elsamra, Thomas L Jang, Eric A Singer, Robert E Weiss
Background: Radical cystectomy (RC) with ileal conduit (IC) or continent diversion (CD) is standard treatment for high-risk non-invasive and muscle-invasive bladder cancer. Objective: Our aim is to study contemporary trends in the utilization of ICs and CDs in patients undergoing RC. Methods: Using the National Inpatient Sample 2001-2012, we identified all patients diagnosed with a malignant bladder neoplasm who underwent RC followed by IC or CD...
January 20, 2018: Bladder Cancer
https://www.readbyqxmd.com/read/29430510/body-mass-index-diet-related-factors-and-bladder-cancer-prognosis-a-systematic-review-and-meta-analysis
#17
Ellen Westhoff, J Alfred Witjes, Neil E Fleshner, Seth P Lerner, Shahrokh F Shariat, Gunnar Steineck, Ellen Kampman, Lambertus A Kiemeney, Alina Vrieling
Background: Urologists are frequently confronted with questions of urinary bladder cancer (UBC) patients about what they can do to improve their prognosis. Unfortunately, it is largely unknown which lifestyle factors can influence prognosis. Objective: To systematically review the available evidence on the association between body mass index (BMI), diet, dietary supplements, and physical activity and UBC prognosis. Methods: We searched PubMed and Embase up to May 2017...
January 20, 2018: Bladder Cancer
https://www.readbyqxmd.com/read/29430509/molecular-correlates-of-in-vitro-responses-to-dacomitinib-and-afatinib-in-bladder-cancer
#18
Shuzo Tamura, Yin Wang, Brendan Veeneman, Daniel Hovelson, Armand Bankhead, Luke J Broses, Guadalupe Lorenzatti Hiles, Monica Liebert, John R Rubin, Kathleen C Day, Maha Hussain, Nouri Neamati, Scott Tomlins, Philip L Palmbos, Petros Grivas, Mark L Day
Background: The HER family of proteins (EGFR, HER2, HER3 and HER4) have long been thought to be therapeutic targets for bladder cancer, but previous clinical trials targeting these proteins have been disappointing. Second generation agents may be more effective. Objective: The aim of this study was to evaluate responses to two second-generation irreversible tyrosine kinase inhibitors, dacomitinib and afatinib, in bladder cancer cell lines. Methods: Cell lines were characterized by targeted next generation DNA sequencing, RNA sequencing, western blotting and flow cytometry...
January 20, 2018: Bladder Cancer
https://www.readbyqxmd.com/read/29430508/decreased-invasion-of-urothelial-carcinoma-of-the-bladder-by-inhibition-of-matrix-metalloproteinase-7
#19
Christian Bolenz, Daniel Knauf, Axel John, Philipp Erben, Annette Steidler, Stefan W Schneider, Cagatay Günes, Christian Gorzelanny
Objectives: To measure and to modulate the invasive potential of urothelial carcinoma of the bladder (UCB) cells in a standardized preclinical setting using broad-spectrum matrix-metalloproteinase (MMPs) inhibitors and specific targeting of MMP7. Materials and Methods: MMP expression levels in UCB cells were determined by quantitative real-time PCR (qRT-PCR) and gel zymographies of cell supernatants (MMP9, MMP2 and MMP1) and cell lysates (MMP7). The invasiveness of human UCB cells (HT1197 and T24/83) and human benign urothelial cells (UROtsa) was modulated by a broad-spectrum MMP inhibitor (4-Aminobenzoyl-Gly-Pro-D-Leu-D-Ala hydroxamic acid; AHA) and by MMP7 specific siRNAs...
January 20, 2018: Bladder Cancer
https://www.readbyqxmd.com/read/29430507/peri-operative-chemotherapy-for-bladder-cancer-a-survey-of-providers-to-determine-barriers-and-enablers
#20
Melanie Walker, R Christopher Doiron, Simon D French, Kelly Brennan, Deb Feldman-Stewart, D Robert Siemens, William J Mackillop, Christopher M Booth
Background: Utilization of chemotherapy for patients with muscle-invasive bladder cancer (MIBC) is low. In earlier qualitative work we used the Theoretical Domains Framework (TDF) to determine barriers and enablers of chemotherapy use. In this project we aimed to determine the prevalence of these barriers and enablers in Canadian physicians. Methods: Practicing Canadian urologists, medical oncologists (MOs) and radiation oncologists (ROs) participated in a specialty-specific web-based quantitative survey to assess potential barriers and enablers to chemotherapy use...
January 20, 2018: Bladder Cancer
journal
journal
52783
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"