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Antioxidants (Basel, Switzerland)

Muhammad Sarfraz, Sharoon Griffin, Tamara Gabour Sad, Rama Alhasan, Muhammad Jawad Nasim, Muhammad Irfan Masood, Karl Herbert Schäfer, Chukwunonso E C C Ejike, Cornelia M Keck, Claus Jacob, Azubuike P Ebokaiwe
Nanosizing represents a straight forward technique to unlock the biological activity of complex plant materials. The aim of this study was to develop herbal nanoparticles with medicinal value from dried leaves and stems of Loranthus micranthus with the aid of ball-milling, high speed stirring, and high-pressure homogenization techniques. The milled nanoparticles were characterized using laser diffraction analysis, photon correlation spectroscopy analysis, and light microscopy. The average size of leaf nanoparticles was around 245 nm and that of stem nanoparticles was around 180 nm...
April 20, 2018: Antioxidants (Basel, Switzerland)
Lucia Padalino, Isabella D'Antuono, Miriana Durante, Amalia Conte, Angela Cardinali, Vito Linsalata, Giovanni Mita, Antonio F Logrieco, Matteo Alessandro Del Nobile
BACKGROUND: During recent years food industries generally produce a large volume of wastes both solid and liquid, representing a disposal and potential environmental pollution problem. OBJECTIVE: The goal of the study was to optimize, from both sensory and nutritional points of view, the formulation of durum wheat spaghetti enriched with an olive oil industrial by-product, indicated as olive paste. METHODS: Three consecutive steps were carried out...
April 16, 2018: Antioxidants (Basel, Switzerland)
Serena Mulè, Mariagiovanna Falla, Alessandra Conti, Dora Castiglione, Isabella Blanco, Armando Platania, Maurizio D'Urso, Marina Marranzano
BACKGROUND: Dietary intake of macronutrient and foods is considered crucial to decrease the risk of diet-related non-communicable diseases. METHODS: The aim of this study was to describe the intake of major food groups and macronutrients in a random sample of 1838 southern Italian adults. RESULTS: No significant differences of macronutrient consumption between sexes were found. By contrast, younger individuals had significantly higher intake of animal protein than older ones...
April 15, 2018: Antioxidants (Basel, Switzerland)
Rattanamanee Chomchan, Panupong Puttarak, Adelheid Brantner, Sunisa Siripongvutikorn
Ricegrass juice ( Oryza sativa L.) was introduced as a functional food as the consumption of sprouts or seedlings has been claimed to provide high nutritive value. Selenium (Se) is a trace mineral that plays a key role in the human antioxidation scheme. Supplementation of Se into plants is one strategy to enhance plant bioactivities, and the consumption of Se plant foods may confer superior health benefits. In this study, ricegrass juice extract was analyzed for its major phenolic components. The effect of ricegrass juice extracts bio-fortified with 0, 10 and 40 mg Se/L named as RG0, RG10, and RG40, respectively, were investigated for a percentage of cell viability, changes of endogenous antioxidant enzymes, lipid peroxidation, and nitric oxide inhibition in RAW264...
April 13, 2018: Antioxidants (Basel, Switzerland)
Armando Platania, Dora Castiglione, Dario Sinatra, Maurizio D' Urso, Marina Marranzano
The aim of the present study was to investigate the total water intake (TWI) from drinks and foods and to evaluate the correlation between the different types of drinks on energy and antioxidant intake. The cohort comprised 1602 individuals from the city of Catania in Southern Italy. A food frequency questionnaire was administered to assess dietary and water intake. The mean total water intake was 2.7 L; more than about two thirds of the sample met the European recommendations for water intake. Water and espresso coffee were the most consumed drinks...
April 9, 2018: Antioxidants (Basel, Switzerland)
Sudip Banerjee, Sumit K Shah, Stepan B Melnyk, Rupak Pathak, Martin Hauer-Jensen, Snehalata A Pawar
Gamma-tocotrienol (GT3) confers protection against ionizing radiation (IR)-induced injury. However, the molecular targets that underlie the protective functions of GT3 are not yet known. We have reported that mice lacking CCAAT enhancer binding protein delta ( Cebpd-/- ) display increased mortality to IR due to injury to the hematopoietic and intestinal tissues and that Cebpd protects from IR-induced oxidative stress and cell death. The purpose of this study was to investigate whether Cebpd mediates the radio protective functions of GT3...
April 6, 2018: Antioxidants (Basel, Switzerland)
James Friel, Wafaa Qasem, Chenxi Cai
The first 6 months of life is a crucial time in meeting iron needs. The purpose of this review is to examine iron in mother's milk and whether or not it meets the physiological needs of the growing infant. Key issues include iron content and iron transport from the mammary gland as well as when and what foods should be added to the solely breastfed infant. We examine these topics in light of new molecular biology findings in the mammary gland.
April 6, 2018: Antioxidants (Basel, Switzerland)
Maria Graça Miguel
Natural pigments are largely distributed in the plant kingdom. They belong to diverse groups, with distinct biochemical pathways. Betalains with colours that range from yellow to red-violet can de divided into two main subgroups: betaxanthins and betacyanins. These types of pigments are confined into 13 families of the order Caryophyllales and in some genera of higher fungi ( Amanita muscaria , Hygrocybe and Hygrophorus ). The Amaranthaceae family includes diverse genera in which betalains are present: Alternanthera , Amaranthus , Beta , Chenopodium , Celosia and Gomphrena ...
April 4, 2018: Antioxidants (Basel, Switzerland)
Abbey Symes, Amin Shavandi, Hongxia Zhang, Isam A Mohamed Ahmed, Fahad Y Al-Juhaimi, Alaa El-Din Ahmed Bekhit
Asparagus officinalis are perennial plants that require re-planting every 10–20 years. The roots are traditionally mulched in the soil or treated as waste. The A. officinalis roots (AR) contain valuable bioactive compounds that may have some health benefiting properties. The aim of this study was to investigate the total polyphenol and flavonoid contents (TPC and TFC, respectively) and antioxidant (2,2-diphenyl-1-picrylhydrazyl (DPPH), Oxygen Radical Absorbance Capacity (ORAC) and Ferric Reducing/Antioxidant Power (FRAP) assays) activities of New Zealand AR extract...
April 4, 2018: Antioxidants (Basel, Switzerland)
Kumpei Tanisawa, Katsuhiko Suzuki, Sihui Ma, Saki Kondo, Susumu Okugawa, Mitsuru Higuchi
We aimed to examine the effects of ingestion of different amounts of carbohydrate (CHO) after endurance exercise on neutrophil count, circulating cytokine levels, and the markers of neutrophil activation and muscle damage. Nine participants completed three separate experimental trials consisting of 1 h of cycling exercise at 70% V · O₂ max, followed by ingestion of 1.2 g CHO·kg body mass-1 ·h-1 (HCHO trial), 0.2 g CHO·kg body mass-1 ·h-1 (LCHO trial), or placebo (PLA trial) during the 2 h recovery phase in random order...
April 2, 2018: Antioxidants (Basel, Switzerland)
Athanasios Z Jamurtas
Exercise-induced muscle damage (EIMD) is associated with muscle soreness or discomfort and amarked decline of muscle strength during the first 12–72 hours post-exercise [1].[...].
March 28, 2018: Antioxidants (Basel, Switzerland)
Jean-Claude Lavoie, André Tremblay
Oxidative stress is a critical process that triggers several diseases observed in premature infants. Growing recognition of the detriment of oxidative stress in newborns warrants the use of an antioxidant strategy that is likely to be nutritional in order to restore redox homeostasis. It appears essential to have a personalized approach that will take into account the age of gestation at birth and the sex of the infant. However, the link between sex and oxidative stress remains unclear. The aim of this study was to find a common denominator explaining the discrepancy between studies related to sex-specific effects of oxidative stress...
March 27, 2018: Antioxidants (Basel, Switzerland)
Ye Zhijing, Amin Shavandi, Roland Harrison, Alaa El-Din A Bekhit
The effect of vinification techniques on phenolic compounds and antioxidant activity of wine lees are poorly understood. The present study investigated the antioxidant activity of white and red wine lees generated at early fermentation and during aging. In this study, the total phenol content (TPC), total tannin content (TTC), mean degree of polymerization (mDP), and antioxidant activities of five white and eight red wine lees samples from different vinification backgrounds were determined. The results showed that vinification techniques had a significant ( p < 0...
March 25, 2018: Antioxidants (Basel, Switzerland)
Sally L Elshaer, Tahira Lemtalsi, Azza B El-Remessy
Diabetes and hyperglycemia are associated with increased retinal oxidative and nitrative stress and vascular cell death. Paradoxically, high glucose stimulates expression of survival and angiogenic growth factors. Therefore, we examined the hypothesis that high glucose-mediated tyrosine nitration causes inhibition of the survival protein PI3-kinase, and in particular, its regulatory p85 subunit in retinal endothelial cell (EC) cultures. Retinal EC were cultured in high glucose (HG, 25 mM) for 3 days or peroxynitrite (PN, 100 µM) overnight in the presence or absence of a peroxynitrite decomposition catalyst (FeTPPs, 2...
March 25, 2018: Antioxidants (Basel, Switzerland)
Anita Umerska, Caroline Gaucher, Felipe Oyarzun-Ampuero, Isabelle Fries-Raeth, Florence Colin, María Gabriela Villamizar-Sarmiento, Philippe Maincent, Anne Sapin-Minet
Despite the promising biological and antioxidant properties of curcumin, its medical applications are limited due to poor solubility in water and low bioavailability. Polymeric nanoparticles (NPs) adapted to oral delivery may overcome these drawbacks. Properties such as particle size, zeta potential, morphology and encapsulation efficiency were assessed. Then, the possibility of storing these NPs in a solid-state form obtained by freeze-drying, in vitro curcumin dissolution and cytocompatibility towards intestinal cells were evaluated...
March 24, 2018: Antioxidants (Basel, Switzerland)
Ramiro A Carciochi, Carlos A Sologubik, María B Fernández, Guillermo D Manrique, Leandro Galván D'Alessandro
The kinetics of polyphenol extraction from brewer's spent grain (BSG), using a batch system, ultrasound assistance, and microwave assistance and the evolution of antioxidant capacity of these extracts over time, were studied. The main parameters of extraction employed in the batch system were evaluated, and, by applying response surface analysis, the following optimal conditions were obtained: Liquid/solid ratio of 30:1 mL/g at 80 °C, using 72% ( v / v ) ethanol:water as the solvent system. Under these optimized conditions, ultrasound assistance demonstrated the highest extraction rate and equilibrium yield, as well as shortest extraction times, followed by microwave assistance...
March 23, 2018: Antioxidants (Basel, Switzerland)
Volker Böhm
Vitamin E is the major lipid-soluble antioxidant in the cell antioxidant system and is exclusively obtained from the diet[...].
March 20, 2018: Antioxidants (Basel, Switzerland)
Joelle Khairallah, Shima Sadeghi Ekbatan, Kebba Sabally, Michèle M Iskandar, Raza Hussain, Atef Nassar, Lekha Sleno, Laetitia Rodes, Satya Prakash, Danielle J Donnelly, Stan Kubow
A multistage human gastrointestinal model was used to digest a polyphenol-rich potato extract containing chlorogenic acid, caffeic acid, ferulic acid, and rutin as the primary polyphenols, to assess for their microbial biotransformation and to measure changes in antioxidant capacity in up to 24 h of digestion. The biotransformation of polyphenols was assessed by liquid chromatography-mass spectrometry. Antioxidant capacity was measured by the ferric reducing antioxidant power (FRAP) assay. Among the colonic reactors, parent (poly)phenols were detected in the ascending (AC), but not the transverse (TC) or descending (DC) colons...
March 20, 2018: Antioxidants (Basel, Switzerland)
Laurie G Sherlock, Ashley Trumpie, Laura Hernandez-Lagunas, Sarah McKenna, Susan Fisher, Russell Bowler, Clyde J Wright, Cassidy Delaney, Eva Nozik-Grayck
BACKGROUND: A naturally occurring single nucleotide polymorphism (SNP), (R213 G), in extracellular superoxide dismutase (SOD3), decreases SOD3 matrix binding affinity. Humans and mature mice expressing the R213 G SNP exhibit increased cardiovascular disease but decreased lung disease. The impact of this SNP on the neonatal lung at baseline or with injury is unknown. METHODS: Wild type and homozygous R213 G mice were injected with intraperitoneal bleomycin or phosphate buffered saline (PBS) three times weekly for three weeks and tissue harvested at 22 days of life...
March 14, 2018: Antioxidants (Basel, Switzerland)
Gwendolyn N Y van Gorkom, Roel G J Klein Wolterink, Catharina H M J Van Elssen, Lotte Wieten, Wilfred T V Germeraad, Gerard M J Bos
Vitamin C or ascorbic acid (AA) is implicated in many biological processes and has been proposed as a supplement for various conditions, including cancer. In this review, we discuss the effects of AA on the development and function of lymphocytes. This is important in the light of cancer treatment, as the immune system needs to regenerate following chemotherapy or stem cell transplantation, while cancer patients are often AA-deficient. We focus on lymphocytes, as these white blood cells are the slowest to restore, rendering patients susceptible to often lethal infections...
March 10, 2018: Antioxidants (Basel, Switzerland)
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