journal
MENU ▼
Read by QxMD icon Read
search

Biological Psychiatry: Cognitive Neuroscience and Neuroimaging

journal
https://www.readbyqxmd.com/read/28924621/an-altered-scaffold-for-information-processing-cognitive-control-development-in-adolescents-with-autism
#1
Marjorie Solomon, Jeremy Hogeveen, Lauren Libero, Christine Nordahl
We investigated how cognitive neuroscientific studies during the last decade have advanced understanding of cognitive control from adolescence to young adulthood in individuals with autism spectrum disorder (ASD). To do so, we conducted a selective review of the larger structural, resting state, and diffusion imaging studies of brain regions and networks related to cognitive control that have been conducted since 2007 in individuals with ASD and typical development (TYP) ages 10 to 30 years that examined how these regions and networks support behavioral and task-based fMRI performance on tasks assessing cognitive control during this period...
September 2017: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
https://www.readbyqxmd.com/read/28920096/competition-effects-in-visual-cortex-between-emotional-distractors-and-a-primary-task-in-remitted-depression
#2
Mary L Woody, Vladimir Miskovic, Max Owens, Kiera M James, Cope Feurer, Effua E Sosoo, Brandon E Gibb
BACKGROUND: Attentional biases, particularly difficulty inhibiting attention to negative stimuli, are implicated in risk for major depressive disorder (MDD). The current study examined a neural measure of attentional bias using a continuous index of visuocortical engagement (steady-state visual evoked potentials [SSVEPs]) before and after a negative mood induction in a population at high-risk for MDD recurrence due to a recently remitted MDD (rMDD) episode. Additionally, we examined working memory (WM) capacity as a potential moderator of the link between rMDD and visuocortical responses...
July 2017: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
https://www.readbyqxmd.com/read/28890942/hyperactivation-in-cognitive-control-and-visual-attention-brain-regions-during-emotional-interference-in-adolescent-depression
#3
Natalie L Colich, Tiffany C Ho, Lara C Foland-Ross, Caitlin Eggleston, Sarah J Ordaz, Manpreet K Singh, Ian H Gotlib
BACKGROUND: Individuals with Major Depressive Disorder (MDD) are characterized by biases in attention to negative emotional material. While there is evidence that anomalous functioning in frontocingulate regions may underlie these biases, we know little about the neural correlates of negative emotional biases in depressed adolescents. METHODS: Eighteen adolescents diagnosed with MDD and 21 matched healthy control (CTL) adolescents underwent fMRI while performing an emotional distractor task...
July 2017: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
https://www.readbyqxmd.com/read/28871288/error-specific-cognitive-control-alterations-in-generalized-anxiety-disorder
#4
James F Cavanagh, Alexandria Meyer, Greg Hajcak
BACKGROUND: Trait anxiety is reliably associated with enhanced neural responses following errors: meta analyses have described how the electrophysiological response to errors known as the Error-Related Negativity (ERN) is increased in anxious individuals, particularly in relation to worry. The ERN has been related to a broader class of control signals, particularly via a common theta band denominator, but it is unknown whether worry relates to these alternative medial frontal metrics...
July 2017: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
https://www.readbyqxmd.com/read/28730183/aberrant-cerebellar-connectivity-in-bipolar-disorder-with-psychosis
#5
Ann K Shinn, Youkyung S Roh, Caitlin T Ravichandran, Justin T Baker, Dost Öngür, Bruce M Cohen
BACKGROUND: The cerebellum, which modulates affect and cognition in addition to motor functions, may contribute substantially to the pathophysiology of mood and psychotic disorders, such as bipolar disorder. A growing literature points to cerebellar abnormalities in bipolar disorder. However, no studies have investigated the topographic representations of resting state cerebellar networks in bipolar disorder, specifically their functional connectivity to cerebral cortical networks. METHODS: Using a well-defined cerebral cortical parcellation scheme as functional connectivity seeds, we compared ten cerebellar resting state networks in 49 patients with bipolar disorder and a lifetime history of psychotic features and 55 healthy control participants matched for age, sex, and image signal-to-noise ratio...
July 2017: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
https://www.readbyqxmd.com/read/28730182/tracking-deceased-related-thinking-with-neural-pattern-decoding-of-a-cortical-basal-ganglia-circuit
#6
Noam Schneck, Stefan Haufe, Tao Tu, George A Bonanno, Kevin Ochsner, Paul Sajda, J John Mann
BACKGROUND: Deceased-related thinking is central to grieving and potentially critical to processing of the loss. Self-report measurements might fail to capture important elements of deceased-related thinking and processing. Here, we used a machine learning approach applied to fMRI - known as neural decoding - to develop a measure of ongoing deceased-related processing. METHODS: 23 subjects grieving the loss of a first-degree relative, spouse or partner within 14 months underwent two fMRI tasks...
July 2017: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
https://www.readbyqxmd.com/read/28713866/implications-of-the-hierarchical-structure-of-psychopathology-for-psychiatric-neuroimaging
#7
David H Zald, Benjamin B Lahey
Research into the neurobiological substrates of psychopathology has been impeded by heterogeneity within diagnostic categories, comorbidity among mental disorders, and the presence of symptoms that transcend diagnostic categories. Solutions to these issues increasingly focus neurobiological research on isolated or narrow groupings of symptoms or functional constructs rather than categorical diagnoses. Here we argue for a more integrative approach that also incorporates the broad hierarchical structure of psychopathological symptoms and their etiological mechanisms...
May 2017: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
https://www.readbyqxmd.com/read/28584882/increases-in-intrinsic-thalamocortical-connectivity-and-overall-cognition-following-cognitive-remediation-in-chronic-schizophrenia
#8
Ian S Ramsay, Tasha M Nienow, Angus W MacDonald
BACKGROUND: Thalamic projections to the prefrontal cortex (PFC) are critical for cognition, and disruptions in these circuits are thought to underlie the pathophysiology of schizophrenia. Cognitive remediation (REM) is a behavioral intervention that holds promise for improving cognition and functioning in schizophrenia, however the extent to which it affects thalamo-prefrontal connections has not been researched. This study sought to determine whether patients with schizophrenia who undergo a placebo-controlled trial of REM show increased functional connectivity between the thalamus and PFC, and whether these changes correspond to improvements in cognition...
May 2017: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
https://www.readbyqxmd.com/read/28480336/longitudinal-relationships-among-activity-in-attention-redirection-neural-circuitry-and-symptom-severity-in-youth
#9
Michele A Bertocci, Genna Bebko, Amanda Dwojak, Satish Iyengar, Cecile D Ladouceur, Jay C Fournier, Amelia Versace, Susan B Perlman, Jorge R C Almeida, Michael J Travis, Mary Kay Gill, Lisa Bonar, Claudiu Schirda, Vaibhav A Diwadkar, Jeffrey L Sunshine, Scott K Holland, Robert A Kowatch, Boris Birmaher, David Axelson, Sarah M Horwitz, Thomas Frazier, L Eugene Arnold, Mary A Fristad, Eric A Youngstrom, Robert L Findling, Mary L Phillips
BACKGROUND: Changes in neural circuitry function may be associated with longitudinal changes in psychiatric symptom severity. Identification of these relationships may aid in elucidating the neural basis of psychiatric symptom evolution over time. We aimed to distinguish these relationships using data from the Longitudinal Assessment of Manic Symptoms (LAMS) cohort. METHODS: Forty-one youth completed two study visits (mean=21.3 months). Elastic-net regression (Multiple response Gaussian family) identified emotional regulation neural circuitry that changed in association with changes in depression, mania, anxiety, affect lability, and positive mood and energy dysregulation, accounting for clinical and demographic variables...
May 2017: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
https://www.readbyqxmd.com/read/28435932/default-mode-network-subsystems-are-differentially-disrupted-in-posttraumatic-stress-disorder
#10
Danielle R Miller, Scott M Hayes, Jasmeet P Hayes, Jeffrey M Spielberg, Ginette Lafleche, Mieke Verfaellie
BACKGROUND: Posttraumatic stress disorder (PTSD) is a psychiatric disorder characterized by debilitating re-experiencing, avoidance, and hyperarousal symptoms following trauma exposure. Recent evidence suggests that individuals with PTSD show disrupted functional connectivity in the default mode network, an intrinsic network that consists of a midline core, a medial temporal lobe (MTL) subsystem, and a dorsomedial prefrontal cortex (dMPFC) subsystem. The present study examined whether functional connectivity in these subsystems is differentially disrupted in PTSD...
May 2017: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
https://www.readbyqxmd.com/read/28670630/impaired-suppression-of-delay-period-alpha-and-beta-is-associated-with-impaired-working-memory-in-schizophrenia
#11
Molly A Erickson, Matthew A Albrecht, Benjamin Robinson, Steven J Luck, James M Gold
BACKGROUND: Although people with schizophrenia (PSZ) frequently exhibit reduced working memory capacity relative to healthy comparison subjects (HCS), the mechanisms that underlie this impairment are not yet known. The present study aimed to assess one putative mechanism: impaired suppression of alpha and beta frequency bands during the delay period of a visual working memory task. METHODS: The electroencephalogram (EEG) was recorded from 30 PSZ and 31 HCS while they completed a change detection task in which they were required to remember a briefly presented array of colored squares over an 1800-ms delay interval...
April 2017: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
https://www.readbyqxmd.com/read/28435933/the-c677t-variant-in-mthfr-modulates-associations-between-brain-integrity-mood-and-cognitive-functioning-in-old-age
#12
Florence F Roussotte, Xue Hua, Katherine L Narr, Gary W Small, Paul M Thompson
INTRODUCTION: The C677T functional variant in the methylene-tetrahydrofolate reductase (MTHFR) gene leads to reduced enzymatic activity and elevated blood levels of homocysteine. Hyperhomocysteinemia has been linked with higher rates of cardiovascular diseases, cognitive decline, and late-life depression. METHODS AND MATERIALS: Here, 3D magnetic resonance imaging data was analyzed from 738 individuals (age: 75.5 ± 6.8 years; 438 men/300 women) including 173 Alzheimer's patients, 359 subjects with mild cognitive impairment, and 206 healthy older adults, scanned as part of the Alzheimer's Disease Neuroimaging Initiative (ADNI)...
April 2017: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
https://www.readbyqxmd.com/read/28424797/magnetoencephalography-as-a-tool-in-psychiatric-research-current-status-and-perspective
#13
REVIEW
Peter J Uhlhaas, Peter Liddle, David E J Linden, Anna C Nobre, Krish D Singh, Joachim Gross
The application of neuroimaging to provide mechanistic insights into circuit dysfunctions in major psychiatric conditions and the development of biomarkers are core challenges in current psychiatric research. We propose that recent technological and analytic advances in magnetoencephalography (MEG), a technique that allows measurement of neuronal events directly and noninvasively with millisecond resolution, provides novel opportunities to address these fundamental questions. Because of its potential in delineating normal and abnormal brain dynamics, we propose that MEG provides a crucial tool to advance our understanding of pathophysiological mechanisms of major neuropsychiatric conditions, such as schizophrenia, autism spectrum disorders, and the dementias...
April 2017: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
https://www.readbyqxmd.com/read/28825048/reward-related-ventral-striatum-activity-links-polygenic-risk-for-attention-deficit-hyperactivity-disorder-to-problematic-alcohol-use-in-young-adulthood
#14
Caitlin E Carey, Annchen R Knodt, Emily Drabant Conley, Ahmad R Hariri, Ryan Bogdan
BACKGROUND: Problematic alcohol use in adolescence and adulthood is a common and often debilitating correlate of childhood attention-deficit/hyperactivity disorder (ADHD). Converging evidence suggests that ADHD and problematic alcohol use share a common additive genetic basis, which may be mechanistically related to reward-related brain function. In the current study, we examined whether polygenic risk for childhood ADHD is linked to problematic alcohol use in young adulthood through alterations in reward-related activity of the ventral striatum, a neural hub supporting appetitive behaviors and reinforcement learning...
March 2017: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
https://www.readbyqxmd.com/read/28758152/sleep-deprivation-disrupts-recall-of-conditioned-fear-extinction
#15
Laura D Straus, Dean T Acheson, Victoria B Risbrough, Sean P A Drummond
BACKGROUND: Learned fear is crucial in the development and maintenance of posttraumatic stress disorder (PTSD) and other anxiety disorders, and extinction of learned fear is necessary for response to exposure-based treatments. In humans, research suggests disrupted sleep impairs consolidation of extinction, though no studies have examined this experimentally using total sleep deprivation. METHODS: Seventy-one healthy controls underwent a paradigm to acquire conditioned fear to a visual cue...
March 2017: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
https://www.readbyqxmd.com/read/28740870/reduced-ventral-tegmental-area-hippocampal-connectivity-in-children-and-adolescents-exposed-to-early-threat
#16
Hilary A Marusak, Joshua R B Hatfield, Moriah E Thomason, Christine A Rabinak
BACKGROUND: Preclinical data suggest that early life stress has detrimental effects on the brain's dopaminergic system, particularly the mesocorticolimbic pathway. Altered dopamine function is thought to contribute to the development of stress-related pathologies; yet, little is known about the impact of early stress on dopamine systems during childhood and adolescence, when stress-related disorders frequently emerge. Here, we evaluate the impact of early threat exposure (violence, abuse) on functional connectivity of putative dopaminergic midbrain regions, the ventral tegmental area (VTA) and substantia nigra (SN), giving rise to mesocorticolimbic and nigrostriatal pathways, respectively...
March 2017: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
https://www.readbyqxmd.com/read/28736755/risky-decision-making-in-neurofibromatosis-type-1-an-exploratory-study
#17
Rachel K Jonas, EunJi Roh, Caroline A Montojo, Laura A Pacheco, Tena Rosser, Alcino J Silva, Carrie E Bearden
BACKGROUND: Neurofibromatosis type 1 (NF1) is a monogenic disorder affecting cognitive function. About one third of children with NF1 have attentional disorders, and the cognitive phenotype is characterized by impairment in prefrontally-mediated functions. Mouse models of NF1 show irregularities in GABA release and striatal dopamine metabolism. We hypothesized that youth with NF1 would show abnormal behavior and neural activity on a task of risk-taking reliant on prefrontal-striatal circuits...
March 2017: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
https://www.readbyqxmd.com/read/28503670/encoding-of-contextual-fear-memory-requires-de-novo-proteins-in-the-prelimbic-cortex
#18
Valerio Rizzo, Khalid Touzani, Bindu L Raveendra, Supriya Swarnkar, Joan Lora, Beena M Kadakkuzha, Xin-An Liu, Chao Zhang, Doron Betel, Robert W Stackman, Sathyanarayanan V Puthanveettil
BACKGROUND: Despite our understanding of the significance of the prefrontal cortex in the consolidation of long-term memories (LTM), its role in the encoding of LTM remains elusive. Here we investigated the role of new protein synthesis in the mouse medial prefrontal cortex (mPFC) in encoding contextual fear memory. METHODS: Because a change in the association of mRNAs to polyribosomes is an indicator of new protein synthesis, we assessed the changes in polyribosome-associated mRNAs in the mPFC following contextual fear conditioning (CFC) in the mouse...
March 2017: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
https://www.readbyqxmd.com/read/28367515/shared-microstructural-features-of-behavioral-and-substance-addictions-revealed-in-areas-of-crossing-fibers
#19
Sarah W Yip, Kristen P Morie, Jiansong Xu, R Todd Constable, Robert T Malison, Kathleen M Carroll, Marc N Potenza
BACKGROUND: Similarities between behavioral and substance addictions exist. However, direct neurobiological comparison between addictive disorders is rare. Determination of disorder-specificity (or lack thereof) of alterations within white-matter microstructures will advance understanding of the pathophysiology of addictions. METHODS: We compared white-matter microstructural features between individuals with gambling disorder (GD; n=38), cocaine-use disorder (CUD; n=38) and healthy comparison (HC; n=38) participants, as assessed using diffusion-weighted magnetic resonance imaging (dMRI)...
March 2017: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
https://www.readbyqxmd.com/read/28367514/impulsive-antisocial-dimension-of-psychopathy-linked-to-enlargement-and-abnormal-functional-connectivity-of-the-striatum
#20
Cole Korponay, Maia Pujara, Philip Deming, Carissa Philippi, Jean Decety, David S Kosson, Kent A Kiehl, Michael Koenigs
BACKGROUND: Psychopathy is a mental health disorder characterized by callous and impulsive antisocial behavior, and is associated with a high incidence of violent crime, substance abuse, and recidivism. Recent studies suggest that the striatum may be a key component of the neurobiological basis for the disorder, though structural findings have been mixed and functional connectivity of the striatum in psychopathy has yet to be fully examined. METHODS: We performed a multimodal neuroimaging study of striatum volume and functional connectivity in psychopathy, using a large sample of adult male prison inmates (N=124)...
March 2017: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
journal
journal
52708
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"