journal
MENU ▼
Read by QxMD icon Read
search

Papillomavirus Research

journal
https://www.readbyqxmd.com/read/30267774/long-term-survival-and-swallowing-outcomes-in-advanced-stage-oropharyngeal-squamous-cell-carcinomas
#1
Jessica M Clark, Emma M Holmes, Daniel A O'Connell, Jeffrey Harris, Hadi Seikaly, Vincent L Biron
BACKGROUND: There is a paucity of studies reporting long-term survival outcomes for HPV/p16 positive oropharyngeal squamous cell carcinoma (OPSCC). This study aims to compare long-term outcomes of advanced stage p16 positive and negative OPSCCs, treated by surgical and non-surgical modalities. METHODS: OPSCC patients from 1998-2012 were identified through a prospectively collected cancer registry. P16 immunohistochemistry was used as a surrogate marker for HPV-OPSCC...
September 26, 2018: Papillomavirus Research
https://www.readbyqxmd.com/read/30244072/oncogenic-human-papillomavirus-infection-and-genotypes-characterization-among-sexually-active-women-in-tenkodogo-at-burkina-faso-west-africa
#2
Rogomenoma Alice Ouedraogo, Théodora Mahoukèdè Zohoncon, Sindimalgdé Patricia Guigma, Ina Marie Angèle Traore, Abdoul Karim Ouattara, Marie Ouedraogo, Florencia Wendkuuni Djigma, Dorcas Obiri-Yeboah, Charlemagne Ouedraogo, Jacques Simpore
OBJECTIVE: This study was conducted to determine the prevalence and distribution of high-risk human papillomavirus (HR-HPV) genotypes among sexually active women in Tenkodogo, Burkina Faso. METHODS: Among 131 sexually active women attending the Tenkodogo Urban Medical Center, endocervical samples were collected prior to screening for precancerous lesions. After viral DNA extraction, fourteen HR-HPV genotypes were characterized by real-time multiplex PCR in these cervical samples...
September 19, 2018: Papillomavirus Research
https://www.readbyqxmd.com/read/30118852/anogenital-human-papillomavirus-virus-dna-and-sustained-response-to-the-quadrivalent-hpv-vaccine-in-women-living-with-hiv-1
#3
Michelle S Cespedes, Minhee Kang, Erna Milunka Kojic, Triin Umbleja, Catherine Godfrey, Jennifer Y Webster-Cyriaque, Reena Masih, Cynthia Firnhaber, Beatriz Grinsztejn, Alfred Saah, Susan Cu-Uvin, Judith A Aberg
OBJECTIVES: People living with HIV have increased Human Papillomavirus (HPV) related lesions and malignancies. We describe HPV DNA recovered from the cervix and anal canal, explore the effect of vaccination on HPV detection, and examine the durability of vaccine titers in women living with HIV-1 who were vaccinated with the quadrivalent HPV vaccine. METHODS: AIDS Clinical Trials Group A5240 was a prospective study of the quadrivalent HPV (qHPV) vaccine in 315 HIV-1 infected women in three CD4 strata (A: >350, B; 201-350, C: ≤200 cells/mm3 )...
August 16, 2018: Papillomavirus Research
https://www.readbyqxmd.com/read/30092369/variants-in-immune-related-genes-and-genital-hpv-16-persistence-in-men
#4
Bigyan Mainali, Matthew B Schabath, Staci L Sudenga, Cynthia Ye, Howard W Wiener, Luisa L Villa, Anna R Giuliano, Sadeep Shrestha
OBJECTIVES: While most human papillomavirus (HPV) infection clears on its own, persistent HPV infection can cause genital warts and anal, penile and oropharyngeal cancers in men. We conducted genetic analysis in a sub-cohort of the HPV infection in men (HIM) study to test the hypothesis that differences in host genes influence HPV persistence in men. METHODS: Baseline and longitudinal genital HPV status at the genitals was measured every 6-months using the Linear Array assay amplified HPV L1 gene fragment using the PGMY09/11 L1 consensus primer system...
August 6, 2018: Papillomavirus Research
https://www.readbyqxmd.com/read/29807614/murine-hpv16-e7-expressing-transgenic-skin-effectively-emulates-the-cellular-and-molecular-features-of-human-high-grade-squamous-intraepithelial-lesions
#5
Z K Tuong, K Noske, P Kuo, A A Bashaw, S M Teoh, I H Frazer
Currently available vaccines prevent HPV infection and development of HPV-associated malignancies, but do not cure existing HPV infections and dysplastic lesions. Persistence of infection(s) in immunocompetent patients may reflect induction of local immunosuppressive mechanisms by HPV, providing a target for therapeutic intervention. We have proposed that a mouse, expressing HPV16 E7 oncoprotein under a Keratin 14 promoter (K14E7 mice), and which develops epithelial hyperplasia, may assist with understanding local immune suppression mechanisms that support persistence of HPV oncogene-induced epithelial hyperplasia...
June 2018: Papillomavirus Research
https://www.readbyqxmd.com/read/29807613/prevalence-and-correlates-of-beta-human-papillomavirus-detection-in-fingernail-samples-from-mid-adult-women
#6
Rachel L Winer, Tarik Gheit, Stephen Cherne, John Lin, Joshua E Stern, Mario Poljak, Qinghua Feng, Massimo Tommasino
Cutaneous human papillomaviruses (HPVs) have not been evaluated in fingernails from healthy individuals. To determine prevalence and correlates of β-HPVs in fingernails from healthy mid-adult women, we tested archived samples collected from 2011 to 2012 using a multiplex PCR combined with Luminex technology for 46 β-HPV genotypes. One hundred thirteen (61.1%) of 185 fingernail samples were positive for β-HPV, and the median number of types detected in positive samples was 2 (interquartile range: 1-4). The most common genotypes detected were HPV-23 (β-2) (13...
June 2018: Papillomavirus Research
https://www.readbyqxmd.com/read/29723682/intra-host-sequence-variability-in-human-papillomavirus
#7
Racheal S Dube Mandishora, Kristina S Gjøtterud, Sonja Lagström, Babill Stray-Pedersen, Kerina Duri, Nyasha Chin'ombe, Mari Nygård, Irene Kraus Christiansen, Ole Herman Ambur, Mike Z Chirenje, Trine B Rounge
Human papillomaviruses (HPVs) co-evolve slowly with the human host and each HPV genotype displays epithelial tropisms. We assessed the evolution of intra HPV genotype variants within samples, and their association to anogenital site, cervical cytology and HIV status. Variability in the L1 gene of 35 HPV genotypes was characterized phylogenetically using maximum likelihood, and portrayed by phenotype. Up to a thousand unique variants were identified within individual samples. In-depth analyses of the most prevalent genotypes, HPV16, HPV18 and HPV52, revealed that the high diversity was dominated by a few abundant variants...
June 2018: Papillomavirus Research
https://www.readbyqxmd.com/read/29689311/time-and-temperature-dependent-analytical-stability-of-dry-collected-evalyn-hpv-self-sampling-brush-for-cervical-cancer-screening
#8
Ditte Møller Ejegod, Helle Pedersen, Garazi Peña Alzua, Camilla Pedersen, Jesper Bonde
As a new initiative, HPV self-sampling to non-attenders using the dry Evalyn self-sampling brush is offered in the Capital Region of Denmark. The use of a dry brush is largely uncharted territory in terms of analytical stability. In this study we aim to provide evidence on the analytical quality of dry HPV self-sampling brushes as a function of time and temperature. We assessed the analytical stability of dry stored Evalyn brushes at three different temperatures, (4 °C, room temperature, 30 °C) and five different storage time points; T = 0 (baseline), 2, 4, 8, 16, and 32 weeks prior to HPV analysis using the BD Onclarity HPV assay...
June 2018: Papillomavirus Research
https://www.readbyqxmd.com/read/29665430/awareness-of-cervical-cancer-and-willingness-to-be-vaccinated-against-human-papillomavirus-in-mozambican-adolescent-girls
#9
Azucena Bardají, Carolina Mindu, Orvalho J Augusto, Aina Casellas, Olga Cambaco, Egas Simbine, Graça Matsinhe, Eusébio Macete, Clara Menéndez, Esperança Sevene, Khátia Munguambe
Sub-Saharan Africa concentrates the largest burden of cervical cancer worldwide. The introduction of the HPV vaccination in this region is urgent and strategic to meet global health targets. This was a cross-sectional study conducted in Mozambique prior to the first round of the HPV vaccine demonstration programme. It targeted girls aged 10-19 years old identified from schools and households. Face-to-face structured interviews were conducted. A total of 1147 adolescents were enrolled in three selected districts of the country...
June 2018: Papillomavirus Research
https://www.readbyqxmd.com/read/29660489/prevalence-of-mucosal-and-cutaneous-human-papillomavirus-in-moroccan-breast-cancer
#10
Amal ElAmrani, Tarik Gheit, Mustapha Benhessou, Sandrine McKay-Chopin, Mohammed Attaleb, Souha Sahraoui, Mohammed El Mzibri, Marilys Corbex, Massimo Tommasino, Meriem Khyatti
BACKGROUND: Due to recent technical improvements and some encouraging new results, there has been a resurgence of interest in the possibility that a substantial proportion of breast cancers (BCs) may be caused by viral infections, including Human papillomavirus (HPV). The aim of this study was to determine the prevalence of mucosal and cutaneous HPV in tumours from Moroccan BC patients. MATERIALS AND METHODS: Frozen tumours from 76 BC cases and 12 controls were evaluated for the presence of 62 HPV-types using highly sensitive assays that combine multiplex polymerase chain reaction and bead-based Luminex technology...
June 2018: Papillomavirus Research
https://www.readbyqxmd.com/read/29649654/hpv-dna-methylation-at-the-early-promoter-and-e1-e2-integrity-a-comparison-between-hpv16-hpv18-and-hpv45-in-cervical-cancer
#11
Sérgio Menezes Amaro-Filho, Cláudia Bessa Pereira Chaves, Shayany Pinto Felix, Diogo Lisbôa Basto, Liz Maria de Almeida, Miguel Angelo Martins Moreira
OBJECTIVES: To compare and describe type-specific characteristics of HPV16, HPV18 and HPV45 in cervical cancer with respect to 3'LCR methylation and disruption of E1/E2. METHODS: The methylation level of 137 cervical cancer samples (70 with HPV16, 37 with HPV18, and 30 with HPV45) of Brazilian patients was analyzed by pyrosequencing. PCR amplifications were performed to characterize E1 and E2 disruption as an episomal surrogate. RESULTS: The 3'LCR of HPV16 showed a higher methylation at all CpG sites (7%, 9%, 11%, 10% and 10%) than homologous HPV18 regions (4%, 5%...
June 2018: Papillomavirus Research
https://www.readbyqxmd.com/read/29626643/patterns-of-repeated-anal-cytology-results-among-hiv-positive-and-hiv-negative-men-who-have-sex-with-men
#12
Hilary A Robbins, Dorothy J Wiley, Ken Ho, Michael Plankey, Susheel Reddy, Nancy Joste, Teresa M Darragh, Elizabeth C Breen, Stephen Young, Gypsyamber D'Souza
BACKGROUND: Men who have sex with men (MSM) are at increased risk for anal cancer. In cervical cancer screening, patterns of repeated cytology results are used to identify low- and high-risk women, but little is known about these patterns for anal cytology among MSM. METHODS: We analyzed Multicenter AIDS Cohort Study (MACS) data for MSM who were offered anal cytology testing annually (HIV-positive) or every 2 years (HIV-negative) for 4 years. RESULTS: Following an initial negative (normal) cytology, the frequency of a second negative cytology was lower among HIV-positive MSM with CD4 ≥ 500 (74%) or CD4 < 500 (68%) than HIV-negative MSM (83%) (p < 0...
June 2018: Papillomavirus Research
https://www.readbyqxmd.com/read/29578098/influencers-and-preference-predictors-of-hpv-vaccine-uptake-among-us-male-and-female-young-adult-college-students
#13
A Scott LaJoie, Jelani C Kerr, Richard D Clover, Diane M Harper
OBJECTIVE: The purpose of the study was to assess the knowledge, attitudes and beliefs of male and female college students in Kentucky about HPV associated diseases and vaccines, and to determine which parameters predicted self-reported uptake of HPV vaccination. MATERIALS AND METHODS: A self-selected cross-sectional sample of college students completed an evidence-based online survey. RESULTS: Of approximately 1200 potential respondents, 585 completed the survey...
June 2018: Papillomavirus Research
https://www.readbyqxmd.com/read/29578097/are-two-doses-of-human-papillomavirus-vaccine-sufficient-for-girls-aged-15-18-years-results-from-a-cohort-study-in-india
#14
Neerja Bhatla, Bhagwan M Nene, Smita Joshi, Pulikottil O Esmy, Usha Rani Reddy Poli, Geeta Joshi, Yogesh Verma, Eric Zomawia, Sharmila Pimple, Priya R Prabhu, Partha Basu, Richard Muwonge, Sanjay Hingmire, Catherine Sauvaget, Eric Lucas, Michael Pawlita, Tarik Gheit, Kasturi Jayant, Sylla G Malvi, Maqsood Siddiqi, Angelika Michel, Julia Butt, Subha Sankaran, Thiraviam Pillai Rameshwari Ammal Kannan, Rintu Varghese, Uma Divate, Martina Willhauck-Fleckenstein, Tim Waterboer, Martin Müller, Peter Sehr, Alka Kriplani, Gauravi Mishra, Radhika Jadhav, Ranjit Thorat, Massimo Tommasino, M Radhakrishna Pillai, Rengaswamy Sankaranarayanan
Extending two-dose recommendations of HPV vaccine to girls between 15 and 18 years will reduce program cost and improve compliance. Immunogenicity and vaccine targeted HPV infection outcomes were compared between 1795 girls aged 15-18 years receiving two (1-180 days) and 1515 girls of same age receiving three (1-60-180 days) doses. Immunogenicity outcomes in 15-18 year old two-dose recipients were also compared with the 10-14 year old three-dose (N = 2833) and two-dose (N = 3184) recipients. The 15-18 year old two-dose recipients had non-inferior L1-binding antibody titres at seven months against vaccine-targeted HPV types compared to three-dose recipients at 15-18 years and three-dose recipients at 10-14 years of age...
June 2018: Papillomavirus Research
https://www.readbyqxmd.com/read/29555602/contribution-of-human-papillomavirus-in-neuroendocrine-tumors-from-a-series-of-10-575-invasive-cervical-cancer-cases
#15
Maria Alejo, Laia Alemany, Omar Clavero, Beatriz Quiros, Susana Vighi, Muhieddine Seoud, Chou Cheng-Yang, Suzanne M Garland, Nuria Juanpere, Josep Lloreta, Sara Tous, Jo Ellen Klaustermeier, Wim Quint, F Xavier Bosch, Silvia de Sanjosé, Belen Lloveras
AIMS: Neuroendocrine tumors (NET) of the cervix are rare tumors with a very aggressive course. The human papillomavirus (HPV) has been linked to its etiology. The objective of this study is to describe HPV prevalence and genotype distribution of NET. METHODS AND RESULTS: Forty-nine tumors with histological neuroendocrine features were identified among 10,575 invasive cervical cancer (ICC) cases from an international study. HPV DNA detection was done using SPF10/DEIA /LiPA25 system...
June 2018: Papillomavirus Research
https://www.readbyqxmd.com/read/29555601/seroprevalence-of-hpv-6-11-16-and-18-and-correlates-of-exposure-in-unvaccinated-women-aged-16-64-years-in-puerto-rico
#16
A P Ortiz, G Tortolero-Luna, J Romaguera, C M Pérez, D González, C Muñoz, L González, E Marrero, E Suárez, J M Palefsky, G Panicker, E R Unger
BACKGROUND: To understand risk factors for HPV exposure in Puerto Rican women, we evaluated HPV 6, 11, 16, and 18 serology in women aged living in the San Juan metropolitan area. METHODS: As part of a cross-sectional study, a population-based sample of 524 HPV unvaccinated Hispanic women ages 16-64 years completed face-to-face and computer assisted interviews and provided blood and self-collected anal and cervical specimens. Serology used multiplex virus-like particle based-IgG ELISA and HPV DNA was detected with L1-consensus PCR...
June 2018: Papillomavirus Research
https://www.readbyqxmd.com/read/29555600/identifying-populations-most-susceptible-to-get-benefit-from-broadening-the-scope-for-prevention-of-cervical-cancer-example-from-uruguay
#17
Víctor-Guillermo Sequera, Marisa Mena, Malen Hollmann, Estefani Mani, Viviana Ramas, Sylvia Bonilla, Alicia Guerra, Fernando Borgia
OBJECTIVES: To identify factors associated with high-risk human papillomavirus (HPV) infection and high grade squamous intraepithelial lesion (HSIL) among a high-risk group of HPV-unvaccinated women in Montevideo. METHODS: Participants completed a questionnaire on socio-demographics, sexual behavior and gynecological history and received a gynecological examination. HPV DNA was detected by PCR using MY09/11 primers. Logistic regression analyses were performed to identify factors associated with high-risk HPV infection and HSIL...
June 2018: Papillomavirus Research
https://www.readbyqxmd.com/read/29555599/periodontitis-and-oral-human-papillomavirus-infection-among-hispanic-adults
#18
Ana Patricia Ortiz, Daisy González, José Vivaldi-Oliver, Maira Castañeda, Vivian Rivera, Elba Díaz, Hilmaris Centeno, Cristina Muñoz, Joel Palefsky, Kaumudi Joshipura, Cynthia M Pérez
INTRODUCTION: Research on the association between periodontitis and oral human papilloma virus (HPV) infection is inconsistent. The cross-sectional association of severe periodontitis with oral HPV infection was investigated in a sample of Hispanic adults. METHODS: Data from the 2014-2016 San Juan Overweight Adults Longitudinal Study (n = 740) was analyzed. Periodontitis assessment and self-collection of oral HPV samples followed the National Health and Nutrition Examination Survey methodology...
June 2018: Papillomavirus Research
https://www.readbyqxmd.com/read/29524677/hpv-vaccination-in-male-physicians-a-survey-of-gynecologists-and-otolaryngology-surgeons-attitudes-towards-vaccination-in-themselves-and-their-patients
#19
Claire Stanley, Michael Secter, Sarah Chauvin, Amanda Selk
OBJECTIVE: Attitudes and barriers towards HPV vaccination were explored in a population of male surgeons in Gynecology and Otolaryngology in Ontario, Canada. MATERIALS/METHODS: An internet-based survey was distributed to male residents and physicians affiliated with the departments of Obstetrics and Gynecology, and Otolaryngology at six Ontario universities. The survey consisted of 16 questions (3 demographic, 3 workplace exposure, 6 regarding personal vaccination, and 3 regarding patient vaccination)...
June 2018: Papillomavirus Research
https://www.readbyqxmd.com/read/29524676/are-dental-providers-the-next-line-of-hpv-related-prevention-providers-perceived-role-and-needs
#20
Nolan Kline, Cheryl Vamos, Erika Thompson, Frank Catalanotto, John Petrila, Rita DeBate, Stacey Griner, Coralia Vázquez-Otero, Laura Merrell, Ellen Daley
The rise in HPV-related oropharyngeal cancer incidence necessitates novel prevention efforts including multiple provider types. Although dental providers screen for HPV-related oropharyngeal cancers, little is known about their needs to advance "primordial prevention," or interventions at the earliest possible stage, to prevent HPV-related cancers. This study assessed dentists' and dental hygienists' perceived roles and needs regarding HPV-related primordial prevention. We conducted a mixed-method study with data from focus groups with dentists (n= 33) and dental hygienists (n= 48) and surveys from both provider types (n= 203) among providers from a diverse set of practice settings and geographic communities...
June 2018: Papillomavirus Research
journal
journal
52588
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"