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Burns and Trauma

Thirthar P Vetrichevvel, Sean M Randall, Fiona M Wood, Suzanne Rea, James H Boyd, Janine M Duke
Background: A number of studies report high prevalence of mental health conditions among burn patients. However there is a need to understand differences in the temporal relationship between mental health conditions and intentional and unintentional burns to hasten psychological prevention and intervention. This study aims to compare the socio-demographic profile, burn characteristics and pre- and post-burn psychiatric morbidity of burn patients by intent-of-injury. Methods: De-identified linked hospital, death and mental health (MH) case registry data of burn patients hospitalised in Western Australia between 1 January 1980 and 30 June 2012 were analysed...
2018: Burns and Trauma
Yichao Xu, Xinyuan Jin, Xiaonan Shao, Feng Zheng, Hong Zhou
Background: Severe burn sepsis can lead to high mortality. We explored the valuable prognostic indicators for severe burn sepsis with inhalation lesion. Methods: Thirty-eight severe burn patients with sepsis who were admitted to the Third Affiliated Hospital of Soochow University from August 2014 to December 2017 were retrospectively analyzed. Among them, 22 patients were assigned to the death group and 16 patients to the survival group. Their general information, vital signs, and blood index including serum procalcitonin (PCT) and C-reactive protein (CRP) levels at admission, diagnosis of sepsis, and 1-week post-diagnosis of sepsis were compared...
2018: Burns and trauma
Denisse Mendez-Romero, Audra T Clark, Alana Christie, Steven E Wolf
Background: Severe burn is associated with significant changes in body weight due to resuscitation volumes, fluid shifts, a hypermetabolic state, prolonged bed rest, and caloric intake. Our goal was to quantify and describe trends in weight change in patients with burns of all severities under modern treatment conditions and to identify the time points at which these changes occur. Methods: An institutional review board-approved chart review was conducted of acute burn patients treated at an American Burn Association-verified regional burn center from February 2016 to November 2016...
2018: Burns and Trauma
Peng-Ran Du, Hong-Ting Lu, Xi-Xiang Lin, Li-Feng Wang, Yan-Xia Wang, Xiao-Ming Gu, Xiao-Zhi Bai, Ke Tao, Jing-Jun Zhou
Background: The molecular pattern of severe burn-induced acute lung injury, characterized by cell structure damage and leukocyte infiltration, remains unknown. This study aimed to determine whether calpain, a protease involved in both processes, mediates severe burn-induced acute lung injury. Methods: Rats received full-thickness scald burns covering 30% of the total body surface area, followed by instant fluid resuscitation. MDL28170 (Tocris Bioscience), an inhibitor of calpain, was given intravenously 1 h before or after the scald burn...
2018: Burns and Trauma
Kaiyang Lv, Zhaofan Xia
Following injury, Asian skin has a tendency toward hyperpigmentation and scar formation than Caucasians. A standardized algorithm tailored to Asian patients, especially Chinese patients, is in great demand. Twelve independent, self-selected academic and military physicians from the department of burn/trauma, plastic surgery and dermatology with extensive experience in treating scars were assembled on January 17, 2015, establishing the consensus panel. This consensus was then appraised, drafted, reviewed, and finalized during the following 3 years, aiming to standardize and improve scar prevention and treatment in China...
2018: Burns and trauma
Si Jack Chong, Yee Onn Kok, Rosanna Xiang Ying Tay, Desai Suneel Ramesh, Kok Chai Tan, Bien Keem Tan
Background: Inhalational injury is a major cause of morbidity and mortality in burns patients. This study aims to analyse the clinical outcomes, complications and bacteriology of inhalational burn patients. Methods: A prospective study was done on consecutive admissions to Burn Department, Singapore General Hospital over 15 months from January 2015 to March 2016. Presence of inhalational injury, demographics, complications and outcomes was recorded. Diagnosis of inhalational injury was based on history, symptoms and nasoendoscopy...
2018: Burns and Trauma
Hannah Zhao-Fleming, Audrey Hand, Kelly Zhang, Robert Polak, Armand Northcut, Daron Jacob, Sharmila Dissanaike, Kendra P Rumbaugh
The USA is currently going through an opioid crisis, associated with tremendous economic and societal impacts. In response to this crisis, healthcare professionals are looking for alternative pain management methods, and non-steroidal anti-inflammatory drugs (NSAIDs) are a sensible choice because of their effectiveness after surgical procedures. However, before surgeons start prescribing NSAIDs in place of opioids, it is crucial to first understand their potential post-surgical complications. The goal of this review is to summarize the data obtained through both animal and human studies, which suggest how a dramatic increase in NSAID use may affect these post-surgical complications...
2018: Burns and Trauma
Dmitry Zavlin, Vishwanath Chegireddy, Stefanos Boukovalas, Anna M Nia, Ludwik K Branski, Jeffrey D Friedman, Anthony Echo
Background: Previous reports individually identified different factors that predict death after burns. The authors employed the multi-center American Burn Association's (ABA) National Burn Repository (NBR) to elucidate which parameters have the highest negative impact on burn mortality. Methods: We audited data from the NBR v8.0 for the years 2002-2011 and included 137,061 patients in our study. The cases were stratified into two cohorts based on the primary outcome of death/survival and then evaluated for demographic data, intraoperative details, and their morbidity after admission...
2018: Burns and trauma
Laura Pompermaier, Moustafa Elmasry, Islam Abdelrahman, Mats Fredrikson, Folke Sjöberg, Ingrid Steinvall
Background: Disparity between medical treatment for men and women has been recorded worldwide. However, it is difficult to find out if the disparities in both the use of resources and outcome depend entirely on sex-related discrimination. Our aim was to investigate if there are differences in burn treatments between the sexes. Methods: All patients admitted with burns to Linköping University Hospital during the 16-year period 2000-2015 were included. Interventions were prospectively recorded using the validated Burn SCoring system (BSC)...
2018: Burns and Trauma
Jong Dae Kim, Suk Joon Oh, Sun Gyu Kim, Song Vogue Ahn, Yu Jin Jang, Ban Seok Yang, Ji Yun Jeong, Kwang Jo Kim
Background: This study aimed to investigate the difference between ultrasonographic findings of normal skin and those of re-epithelialized skin after partial-thickness burns and to evaluate the relationship between these findings and clinical outcomes. Methods: This study retrospectively analysed the ultrasound images of re-epithelialized skin after partial-thickness burns and contralateral normal skin from January 2016 to December 2016. A total of 155 lesions from 148 patients were analysed with ultrasound images, and healing time was documented...
2018: Burns and Trauma
Cheng Hean Lo, Simone H Nothdurft, Hye-Sung Park, Eldho Paul, James Leong
Background: The purpose of this study is to present our experience with the modified pins and rubber band traction system, discuss problems encountered, and make recommendations to optimize outcomes. Methods: Data was collected prospectively from November 2013 to March 2017 at a tertiary referral hospital in Melbourne, Australia. Patients with closed complex proximal interphalangeal joint fracture dislocations that were considered unsuitable for other surgical options were included in the study...
2018: Burns and Trauma
Akhtar Bibi, Sundas Kalim, Muhammad Adnan Khalid
Background: Post-traumatic stress disorder (PTSD) is one of the major psychological disorders developed after burn injuries, though this subject of burn injuries and their destructive chronic psychological impact are not considered as thoughtfully in developing countries like Pakistan. Hence, the current study investigated the relationship between PTSD symptoms and resilience among burn patients in Pakistan, exploring the variance occurrence of the two variables concerning male burn patients and female burn patients...
2018: Burns and Trauma
Steven T Boyce, Andrea L Lalley
Engineering of biologic skin substitutes has progressed over time from individual applications of skin cells, or biopolymer scaffolds, to combinations of cells and scaffolds for treatment, healing, and closure of acute and chronic skin wounds. Skin substitutes may be categorized into three groups: acellular scaffolds, temporary substitutes containing allogeneic skin cells, and permanent substitutes containing autologous skin cells. Combined use of acellular dermal substitutes with permanent skin substitutes containing autologous cells has been shown to provide definitive wound closure in burns involving greater than 90% of the total body surface area...
2018: Burns and Trauma
Pippa Kenworthy, Michael Phillips, Tiffany L Grisbrook, William Gibson, Fiona M Wood, Dale W Edgar
Background: Major burns are life threatening. Fluid resuscitation is required for survival to maintain intravascular volumes and prevent hypovolemic shock. Bioimpedance spectroscopy (BIS) has been recognised as a potential method of monitoring fluid shifts after burn and in other disease states. The aims of this study were to examine the reliability of BIS across different dressing conditions and electrode positions, establish the influence of Acticoat™ on BIS variable measures and determine the validity of whole-body BIS to assess net fluid shift in the presence of moderate to major burns...
2018: Burns and trauma
Kevin Serror, Marc Chaouat, Golda Romano, Magali Schmidt, Alice Blet, Maurice Mimoun, David Boccara
Background: In well-selected cases, flaps can play a pivotal role in optimizing outcomes in the acute phase of burns. A previous redundant flap could be reused or recycled as a donor site from which a new flap could be raised. Case presentation: We report the case of a patient with full thickness burns on both legs, leading to the exposure of joints of the right ankle and the right foot and left patellar tendon. The right lower extremity was covered with a free musculo-cutaneous latissimus dorsi flap...
2018: Burns and Trauma
Guangping Tai, Michael Tai, Min Zhao
Naturally occurring electric fields are known to be morphogenetic cues and associated with growth and healing throughout mammalian and amphibian animals and the plant kingdom. Electricity in animals was discovered in the eighteenth century. Electric fields activate multiple cellular signaling pathways such as PI3K/PTEN, the membrane channel of KCNJ15/Kir4.2 and intracellular polyamines. These pathways are involved in the sensing of physiological electric fields, directional cell migration (galvanotaxis, also known as electrotaxis), and possibly other cellular responses...
2018: Burns and Trauma
Andrew Gleadall, Dafydd Visscher, Jing Yang, Daniel Thomas, Joel Segal
Material extrusion additive manufacturing has rapidly grown in use for tissue engineering research since its adoption in the year 2000. It has enabled researchers to produce scaffolds with intricate porous geometries that were not feasible with traditional manufacturing processes. Researchers can control the structural geometry through a wide range of customisable printing parameters and design choices including material, print path, temperature, and many other process parameters. Currently, the impact of these choices is not fully understood...
2018: Burns and Trauma
Ting Xie, Junna Ye, Kittipan Rerkasem, Rajgopal Mani
Venous ulcers are a common chronic problem in many countries especially in Northern Europe and USA. The overall prevalence of this condition is 1% rising to 3% in the over 65 years of age. Over the last 25 years, there have been many developments applicable to its diagnosis and treatment. These advances, notwithstanding healing response and recurrence, are variable, and the venous ulcer continues to be a clinical challenge. The pathogenesis of venous ulcers is unrelieved or ambulatory venous hypertension resulting mostly from deep venous thrombosis leading to venous incompetence, lipodermatosclerosis, leucocyte plugging of the capillaries, tissue hypoxia and microvascular dysfunction...
2018: Burns and trauma
Janine M Duke, Sean M Randall, James H Boyd, Mark W Fear, Suzanne Rea, Fiona M Wood
Background: Injury triggers a range of systemic effects including inflammation and immune responses. This study aimed to compare infectious disease admissions after burn and other types of injury using linked hospital admissions data. Methods: A retrospective longitudinal study using linked health data of all patients admitted with burns in Western Australia ( n  = 30,997), 1980-2012, and age and gender frequency matched cohorts of people with non-burn trauma ( n  = 28,647) and no injury admissions ( n  = 123,399)...
2018: Burns and trauma
Dafydd O Visscher, Sjoerd Te Slaa, Mariëlle E Jaspers, Marloes van de Hulsbeek, Jorien Borst, Jan Wolff, Tymour Forouzanfar, Paul P van Zuijlen
No abstract text is available yet for this article.
2018: Burns and Trauma
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