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Value in Health Regional Issues

Nericke Olivier, Martie Lubbe, Rianda Joubert, Adele Naudé, Johanita Burger
OBJECTIVES: To describe antirheumatic medicine prescribing patterns and to estimate the total annual direct medicine cost of rheumatoid arthritis (RA) in the private health sector of South Africa. METHODS: A retrospective, cross-sectional drug utilization study was performed on medicine claims data from January 1, 2014, to December 31, 2014, for a total of 4,352 patients with RA. Patients were divided into those with RA only and those with RA and other chronic disease list conditions...
September 15, 2018: Value in Health Regional Issues
Gabriel Rodrigues Martins de Freitas, Jeruza Lavanholi Neyeloff, Giacomo Balbinotto Neto, Isabela Heineck
OBJECTIVES: To estimate the proportion of patients with drug-related morbidities (DRMs), DRM preventability, and the cost of illness of the DRMs in Brazil. METHODS: We used the decision-analytic model initially developed by Johnson and Bootman (Drug-related morbidity and mortality. A cost-of-illness model. J Manag Care Pharm 1996;2:39-47), which was adapted to the reality of the present study. A hypothetical cohort of patients in ambulatory care setting was simulated considering the perspective of the Brazilian public health system...
September 5, 2018: Value in Health Regional Issues
John N Yfantopoulos, Athanasios Chantzaras
OBJECTIVES: To provide a detailed overview of the recent reforms in pharmaceutical pricing and reimbursement processes as well as in other important areas of the pharmaceutical policy in Greece. METHODS: Information was collected via a structured questionnaire. The study used publicly available resources, such as publications, relevant legislation, and statistical data, while health experts were also consulted. RESULTS: Recent pharmaceutical reforms included significant price cuts, increased co-payments and some provisions for vulnerable groups, rebates/clawbacks, mandatory electronic prescribing and prescription by international nonproprietary name, generics substitution, prescription limits and detailed auditing, centralized procurement, as well as changes in the pricing and reimbursement processes, with the introduction of positive and negative lists and an internal price referencing system...
September 5, 2018: Value in Health Regional Issues
Elias Asfaw Zegeye, Abduljelli Reshad, Eyersualem Animut Bekele, Belay Aurgessa, Zenebech Gella
Health technology assessment (HTA) has previously been implemented only in a fragmented manner in the Ethiopian health sector decision-making cycle, and the sector has been hampered by limited institutional capacity and skilled human resources to inform evidence-based decision making. The country is in the midst of widescale implementation of a community-based health insurance scheme and is preparing for the launch of a social health insurance scheme. The country continues to face a limited financial resource envelope, undergoing an epidemiological transition, and is facing a much greater burden of noncommunicable diseases, for which the essential health benefit package, defined 12 years ago, may no longer be suitable...
September 5, 2018: Value in Health Regional Issues
Manuel Antonio Espinoza, Ruben Rojas, Hildaura Acosta de Patiño
The interest on Multicriteria decision analysis (MCDA) for healthcare priority setting has grown in popularity in the last few years. Literature shows several exercises where MCDA can be used to inform different types of priorities; however, there is little evidence on the feasibility of implementing this method in current institutionalized decision-making processes. We examined the willingness to implement MCDA as a tool to facilitate decision-making in Central America and the Caribbean (CAC). We convene 41 representatives of the healthcare public sector from 10 countries to explore whether they consider MCDA a robust tool to be incorporated in local priority setting processes and which ongoing decision-making process could be benefited from this methodology...
September 2, 2018: Value in Health Regional Issues
Rafael J Vargas Alves, Ana P Beck da Silva Etges, Giácomo Balbinotto Neto, Carisi Anne Polanczyk
BACKGROUND: A review of the literature on economic analyses in cancer (prevention, diagnosis, and treatment) using activity-based costing (ABC) or time-driven activity-based costing (TDABC) for measuring costs and to examine how these approaches have been applied to assess and manage cancer costs. METHODS: This review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. We conducted a search for studies that used ABC or TDABC to calculate the cost of cancer in prevention, diagnosis, and treatment...
August 24, 2018: Value in Health Regional Issues
Ahmad Al Kadour, Wafa Al Marridi, Daoud Al-Badriyeh
OBJECTIVES: To review literature characteristics, describe methodological trends, and assess the reporting quality of the economic evaluations of oral anticancer drugs (OACDs). METHODS: The review included comparative economic evaluations of OACDs. The search was conducted via PubMed, Embase, EconLit, and Economic Evaluation Database, and studies till December 2017 were included. Using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses checklist, literature inclusion and data extraction were performed in duplicate by separate investigators...
August 22, 2018: Value in Health Regional Issues
Fiona Pearce, Liang Lin, Elaine Teo, Kwong Ng, Daphne Khoo
INTRODUCTION: Singapore has a robust health care system that is well known for delivering good health outcomes. In the public health care sector, subsidies and financial assistance are provided for drugs listed on the Standard Drug List and Medication Assistance Fund. Additional financing mechanisms are also available to provide further support for patients in need. With new technologies entering the market at high costs, health technology assessment (HTA) is playing an increasingly important role to inform their relative value and determine how best to allocate finite health care resources to ensure long-term sustainability of the health care system...
June 25, 2018: Value in Health Regional Issues
María Calderón, Nicole Minckas, Solange Nuñez, Agustín Ciapponi
BACKGROUND: Inflammatory bowel disease (IBD) is the name given to two inflammatory diseases of the colon and/or small intestine: Crohn disease (CD) and ulcerative colitis (UC). There is no information summarizing the complete body of evidence about IBD in developing regions, including Latin America. OBJECTIVES: To estimate the burden of IBD in Latin America. METHODS: We conducted a systematic review searching published and unpublished studies on major international and regional databases from January 2000 to September 2015...
June 21, 2018: Value in Health Regional Issues
Christiane Maskineh, Soumana C Nasser
OBJECTIVES: The first objective is to describe current managed entry agreement (MEA) activity in the Middle East and North African (MENA) region and the pharmaceutical decision makers' perception and use of these agreements; The second objective is to describe the challenges as well as to reflect on the uncertainty related to MEAs implementation and the future outlook for MEAs activities in the region. STUDY DESIGN: A prospective cross-sectional survey. METHODS: A questionnaire was sent to several pharmaceutical manufacturers and public officials involved in pricing and reimbursement of pharmaceuticals in the region...
June 21, 2018: Value in Health Regional Issues
Gustavo L A de Oliveira, Jans B Izidoro, Felipe Ferré, Samuel R A E Sousa, Francisco A Acurcio
OBJECTIVES: To estimate the average price of oral hypoglycemic agents provided by the Brazilian health system (SUS) and to compare them to other public health systems. METHODS: Cross-sectional study about drug prices purchased by Belo Horizonte (municipal level), Minas Gerais (state level) and federal institutions in January and February of 2014. Average prices were calculated by defined daily dosage (DDD) and were compared to the management levels and the program "Aqui Tem Farmácia Popular" (ATFP)...
June 20, 2018: Value in Health Regional Issues
A V Prasolov, A S Kolbin, Yulia E Balykina
OBJECTIVES: To propose an algorithm that relates the effectiveness of drugs for a wide range of diseases with the financial capabilities of patients. METHODS: Estimates of the volume of pharmaceuticals that are consumed in the Russian Federation by all segments of the population regardless of household income were considered. These were calculated using statistically valid probabilities of the appearance of various diseases, official state data on the structure of expenditures of various strata of the population, and the optimal choice of the most effective medicines with income restrictions taken into account...
June 19, 2018: Value in Health Regional Issues
Luciana C Chiapella, Jorgelina Montemarani Menna, María Eugenia Mamprin
OBJECTIVE: This study aims to compare, both qualitatively and quantitatively, the medication dispensed to elderly patients in a primary health care center (PHC) and a community pharmacy (CP) in Argentina and to identify the prescription of potentially inappropriate medications (PIMs). METHODS: A cross-sectional observational study. Data were acquired from 886 prescriptions in the PHC and 2368 in the CP between February and April 2015. Dispensed medications were coded according to the Anatomical, Therapeutic, and Chemical (ATC) classification system...
June 19, 2018: Value in Health Regional Issues
Ramiro E Gilardino, Eduardo González-Pier, Claudia Brabata
End-stage renal disease, the last and most severe stage of chronic kidney disease, represents a major and rising concern for countries in Latin America, driven in large part by aging populations and the near-epidemic rises in diabetes, obesity, and hypertension. This places a great clinical, economic, and social burden on the region's health systems. During the ISPOR 6th Latin America Conference held in Sao Paulo, Brazil, in September 2017, an educational forum debated on value-based decision making in the treatment of end-stage renal disease in Latin America...
May 21, 2018: Value in Health Regional Issues
Emil Kupek, Ilse Viertel
OBJECTIVES: To evaluate cost effectiveness of 10-valent pneumococcal conjugate vaccine in the routine immunization program for children younger than 5 years in Brazil by a postintroduction study. METHODS: Ecological study of prevaccine (2006-2009) versus postvaccine (2011-2014) period related the changes in mortality rate and hospitalization rate to direct cost of pneumonia treatment from the payer's perspective to estimate the cost effectiveness regarding lives saved, life-years gained, and disability-adjusted life-year for children younger than 5 years in the southern Brazilian state of Santa Catarina...
May 14, 2018: Value in Health Regional Issues
Ana Paula Beck da Silva Etges, Veronique Grenon, Joana Siqueira de Souza, Francisco José Kliemann Neto, Elaine Aparecida Felix
BACKGROUND: In recent years, health care organizations have looked to enterprise risk management (ERM) for novel systems to obtain more accurate data on which to base risk strategies. OBJECTIVE: This study proposes a conceptual ERM framework specifically designed for health care organizations. METHODS: We explore how hospitals in the United States and Brazil are structuring and implementing ERM processes within their management structure. This study incorporates interviews with 15 chief risk officers (8 from the United States and 7 from Brazil) with qualitative data analysis using NVivo (QSR International software)...
May 14, 2018: Value in Health Regional Issues
María Calderón, Viviana Brito, Andrea Alcaraz, Lucila Rey-Ares, Federico Augustovski, Sebastián García-Martí, Ariel Bardach, Agustín Ciapponi, Analía López, Andrés Pichón-Riviere
BACKGROUND: Aortic aneurysm (AA) is a pathology with high morbidity and mortality. The management can be expectant, surgical, or through endovascular repair (EVAR). In Latin America the incidence of AA has increased and the analysis of therapeutic options, especially if they are expensive, is fundamental. OBJECTIVE: To analyze available evidence on the effectiveness, safety and coverage policies of the EVAR. METHODOLOGY: Panoramic review in the main bibliographical bases (MEDLINE, LILACS, EMBASE, Cochrane Library, DARE) and generic internet searchers, main health technology assessment (HTA) agencies and health insurance companies...
May 10, 2018: Value in Health Regional Issues
Ângela Maria Bagattini, Suzi Alves Camey, Sandro René Miguel, Mônica Viegas Andrade, Kenya Valeria Micaela de Souza Noronha, Monica Akissue de C Teixeira, Ana Flávia Lima, Marisa Santos, Carisi Anne Polanczyk, Luciane Nascimento Cruz
OBJECTIVES: To assess the measurement equivalence of the original paper version of an adapted tablet version of the EuroQol five-dimensional questionnaire (EQ-5D). METHODS: A randomly selected sample of 509 individuals aged 18 to 64 years from the general population responded to the EQ-5D at two time points separated by a minimum interval of 24 hours and were allocated to one of the following groups: test-retest group (tablet-tablet) or crossover group (paper-tablet and tablet-paper)...
May 10, 2018: Value in Health Regional Issues
Karen Brasil Ruschel, Eneida R Rabelo-Silva, Luis Eduardo Rohde, Emiliane N de Souza, Cláudia M Mussi, Carisi A Polanczyk
OBJECTIVE: Estimate the cost-effectiveness of a nurse-led home visit (HV) intervention as compared with the standard HF management, within a randomized clinical trial in Brazil. STUDY DESIGN: Cost-effectiveness study within a randomized trial. METHODS: To assess the cost-effectiveness of four home visits and four telephone calls by nurses in the management of patients with HF within a randomized clinical trial (RCT: NCT01213875) in a perspective Public (PHS-Public Healthcare System) and private healthcare systems of Brazil during time frame of 24 weeks...
May 10, 2018: Value in Health Regional Issues
Alessandro G Campolina, Rossana V M López, Elene P Nardi, Marcos B Ferraz
OBJECTIVES: To investigate the internal consistency of the SF-6D as a health status index in the Brazilian urban population. STUDY DESIGN: Cross-sectional population based study. METHODS: Five thousand individuals, older than the age of 15, were assessed in the five regions of the country. Two different methods of scoring the SF-6D where compared: "weighting the items" of the questionnaire through the Brazilian official weight coefficients, and "unweighting the items" through a parallel non preference scoring rule solely based on patients' answers to SF-6D health classification system (SF-6DHSI )...
May 7, 2018: Value in Health Regional Issues
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