Amirhossein Jafarian, Masoumeh Jafaripour, Masoumeh Gharib, Maryam Salehi, Nema Mohamadian Roshan, Sare Etemad, Khatoone Mirshekar, Maryam Sheikhi, Masoumeh Heidari, Behnaz Ahmadian, Zahra Khoshnegah, Hossein Ayatollahi, Payam Siyadat
BACKGROUND & OBJECTIVE: Epithelial ovarian cancer (EOC) is the most prevalent type of ovarian cancer. Previous studies have elucidated different pathways for the progression of this malignancy. The mutation in the B-Raf proto-oncogene, serine/threonine kinase (BRAF) gene, a member of the MAPK/ERK signaling pathway, plays a role in the development of EOC. The current study aimed to determine the frequency of the BRAF V600E mutation in ovarian serous and mucinous tumors, including borderline and carcinoma subtypes...
2023: Iranian Journal of Pathology