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Veterinary Record Open

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https://www.readbyqxmd.com/read/29118993/cellular-characteristics-of-keratin-19-positive-canine-hepatocellular-tumours-explain-its-aggressive-behaviour
#1
Renee G van Sprundel, Ted Sgam van den Ingh, Baukje A Schotanus, Monique E van Wolferen, Louis C Penning, Jan Rothuizen, Bart Spee
The expression of the hepatic progenitor cell marker keratin 19 (K19) in canine hepatocellular carcinomas is linked with a poor prognosis. To better understand this aggressive behaviour, K19-positive hepatocellular carcinomas (n=5) and K19-negative hepatocellular adenomas (n=6) were immunohistochemically stained for proteins involved in malignant tumour development. The K19-positive carcinomas showed marked positivity for platelet-derived growth factor receptor alpha polypeptide (PDGFRα), laminin, integrin beta-1/CD29, B-cell-specific Moloney murine leukaemia virus Integration site 1, glypican-3 (GPC-3) and prominin-1/CD133, in contrast with K19-negative hepatocellular adenomas...
2017: Veterinary Record Open
https://www.readbyqxmd.com/read/29018534/factors-related-to-work-and-life-satisfaction-of-veterinary-practitioners-in-germany
#2
Johanna C Kersebohm, Timo Lorenz, Anne Becher, Marcus G Doherr
OBJECTIVES: Veterinary practitioners' working situation is both challenging and changing. They have higher levels of work-related stress and suicide risk than the general population. The proportion of women is increasing, and in Germany especially women and employed veterinarians are reported to be less satisfied than comparable subgroups of the general population. In this study we identified key factors associated with work and life satisfaction among veterinary practitioners in Germany...
2017: Veterinary Record Open
https://www.readbyqxmd.com/read/29018533/pharmacokinetics-of-marbofloxacin-administered-via-intravenous-regional-limb-perfusion-in-dairy-cows-evaluation-of-two-different-tourniquets
#3
Gianluca Celani, Serena Maria Rita Tulini, Camilla Montesano, Daniela Zezza, Manuel Sergi, Vincenzo Varasano, Carlo Maria Mortellaro, Dario Compagnone, Michele Amorena, Lucio Petrizzi
OBJECTIVES: This study evaluated synovial and systemic plasma pharmacokinetic variables of marbofloxacin after a single intravenous regional limb perfusion (IVRLP) performed using two different tourniquets in clinically healthy, standing, non-sedated dairy cows. The authors hypothesised that the type of tourniquet used for IVRLP would influence the synovial fluid concentration of marbofloxacin in the perfused distal limb. DESIGN: The study had a randomised parallel-group design...
2017: Veterinary Record Open
https://www.readbyqxmd.com/read/29018532/real-world-data-of-a-veterinary-teaching-hospital-in-japan-a-pilot-survey-of-prescribed-medicines
#4
Noriko Tanaka, Tsuyoshi Takizawa, Nao Miyamoto, Shinji Funayama, Ryo Tanaka, Syozo Okano, Toshio Iwasaki
The prescription data from a digital accounting system of a veterinary teaching hospital collected between 2008 and 2011 in Japan were downloaded, stored in a database and analysed using a statistical analysis software, SAS. Seventy-six per cent of all prescriptions were drugs approved for human beings. The most frequently prescribed category was 'Agents against pathogenic organisms', such as antibiotics and chemotherapeutic agents, followed by 'Cardiovascular agents'. Seventy-five per cent of prescribed oral formulations in the category 'Agents against pathogenic organisms' were drugs approved for human beings, while 78 per cent of the injectable prescriptions were those for veterinary...
2017: Veterinary Record Open
https://www.readbyqxmd.com/read/29018531/magnetic-resonance-imaging-to-detect-local-tissue-reactions-after-vaccination-in-sheep-in-vivo
#5
Maren Bernau, Prisca Valerie Kremer-Rücker, Lena Sophie Kreuzer, Sebastian Schwanitz, Klaus Cussler, Andreas Hoffmann, Armin Manfred Scholz
OBJECTIVES: Vaccination is one of the most effective methods to keep up the health status in humans and in livestock. Therefore, farm animals are vaccinated several times during their lifetime. Although vaccines are being checked regarding their local reactogenicity, side effects occur frequently-especially in the case of the application of adjuvanted products. Many reports exist about local reactions in sheep. The present study aimed at testing MRI as a method to document injection site reactions three-dimensionally...
2017: Veterinary Record Open
https://www.readbyqxmd.com/read/29018530/benchmarking-welfare-indicators-in-73-free-stall-dairy-farms-in-north-western-spain
#6
Yolanda Trillo, Luis Angel Quintela, Mónica Barrio, Juan José Becerra, Ana Isabel Peña, Marcos Vigo, Pedro Garcia Herradon
The aim of this study was to describe the status of body condition score (BCS), hock injuries prevalence, locomotion and body hygiene score as animal welfare measures in 73 free-stall dairy cattle farms in Lugo (Spain). A benchmarking process was established across farms: (1) the animal-based indicators were ordered from low to high values; (2) The farms were classified into three categories based on the number of indicators within less than the 25th percentile, 25th to 75th percentile and above the 75th percentile...
2017: Veterinary Record Open
https://www.readbyqxmd.com/read/28890791/potential-of-phytoceuticals-to-affect-antibiotic-residue-detection-tests-in-cow-milk-in-a-randomised-trial
#7
Keena Ae Mullen, Erin Beasley, Julio Q Rizzo, Steven P Washburn, Ronald E Baynes, Sharon E Mason, Kevin L Anderson
Mastitis is a costly disease for dairy farmers. Some dairy farmers use herbal products, or phytoceuticals, to treat mastitis. Phytoceuticals have not been approved for this use by the United States Food and Drug Administration, and have not been tested to determine how they impact antibiotic residue detection testing. The current study tested the potential for phytoceuticals to cause positive results on two milk antibiotic residue screening tests, the Delvotest P and Charm SL Beta-lactam test, or to interfere with the detection of antibiotics by these tests...
2017: Veterinary Record Open
https://www.readbyqxmd.com/read/28890790/evaluating-pair-versus-solitary-housing-in-kennelled-domestic-dogs-canis-familiaris-using-behaviour-and-hair-cortisol-a-pilot-study
#8
Emma K Grigg, Belle Marie Nibblett, James Q Robinson, Judit E Smits
Numerous studies conducted to assess welfare of domestic dogs housed in kennel facilities have reported that these dogs experience suboptimal living conditions. One important goal of improving welfare of kennelled dogs is to reduce their stress levels, and one recommended approach for improving welfare of kennelled dogs is group or social housing. The beneficial effects of management changes designed to achieve this goal should be measurable in individual animals. Stress is evident through behaviours exhibited, as well as via the concentration of cortisol, a key hormone reflecting stress...
2017: Veterinary Record Open
https://www.readbyqxmd.com/read/28890789/evaluation-of-blood-metabolites-reflects-presence-or-absence-of-liver-abscesses-in-beef-cattle
#9
Alaina G C Macdonald, Stéphanie L Bourgon, Rupert Palme, Stephen P Miller, Yuri R Montanholi
Liver abscesses constitute a prominent concern regarding animal health and profitability of the beef industry. Our objective was to evaluate potential biliary and blood indicators of liver abscesses. Twenty-nine beef bulls (initially averaging 356±70.5 kg and 253±30 days of age) were fed a high-concentrate diet during a performance test of 112 days, during which blood was collected at nine time points spaced 0.5-13 days apart within 56 days before slaughter. At the abattoir, blood and bile were collected and livers were inspected for liver abscesses...
2017: Veterinary Record Open
https://www.readbyqxmd.com/read/28848652/veterinary-pharmacovigilance-in-europe-a-survey-of-veterinary-practitioners
#10
Nancy De Briyne, Raquel Gopal, Gillian Diesel, Despoina Iatridou, Declan O'Rourke
A web-based survey was conducted by the Federation of Veterinarians of Europe with the support of the European Medicines Agency to gain a better insight into the adverse event reporting habits of veterinary practitioners and the level of information on reported adverse events that flows back to them. It was completed by 3545 veterinarians. The findings indicate marked under-reporting and that the system is poorly equipped to deal with lack of expected efficacy, with few cases reported and most found to be inconclusive...
2017: Veterinary Record Open
https://www.readbyqxmd.com/read/28761669/prevalence-of-individual-and-bulk-tank-milk-antibodies-of-bovine-herpesvirus-type-1-and-its-relation-to-milk-quality-parameters-on-dairy-farms-in-catalonia-north-east-spain
#11
Ramon Armengol, Daniel Villalba, Ester Coma, Lourdes Porquet, Anna Jubert, Carmina Nogareda
Bovine herpesvirus type 1 (BoHV-1) is the causative agent for infectious bovine rhinotracheitis and infectious pustular vulvovaginitis in cows or balanoposthitis in bulls. In this study, individual and bulk tank milk (BTM) samples from 5 Catalan dairy farms with different control strategies against BoHV-1 were analysed during the course of a year for milk quality parameters and glycoprotein E (gE) antibodies. Detection of gE antibodies was carried out with ELISA techniques. Prevalence of BoHV-1 varied between farms, and was stable during the study in individual and BTM samples...
2017: Veterinary Record Open
https://www.readbyqxmd.com/read/28761668/characterisation-of-inla-truncation-in-listeria-monocytogenes-isolates-from-farm-animals-and-human-cases-in-the-province-of-quebec
#12
Philippe Fravalo, Tamazight Cherifi, Kersti Dina Neira Feliciano, Ann Letellier, Julie-Hélène Fairbrother, Sadjia Bekal
The introduction of Listeria monocytogenes into the food production chain is a concern, with numerous grouped cases of listeriosis associated with milk-derived or pork-derived products have been documented. Management of this zoonotic pathogen considers all strains as an equal risk. Recently, a new perspective for characterisation of strain virulence was introduced with the discovery of the unaltered sequence of InlA as a determinant of strain virulence; this has also been reported as an infrequent finding among so-called environmental strains, that is, strains isolated from food or from surfaces in food industries...
2017: Veterinary Record Open
https://www.readbyqxmd.com/read/28761667/correlation-between-capillary-oxygen-saturation-and-small-intestinal-wall-thickness-in-the-equine-colic-patient
#13
Elisabeth Mirle, Anna Wogatzki, Robert Kunzmann, Axel M Schoenfelder, Lutz F Litzke
The surgical evaluation of haemorrhagic infarcted intestine and the decision for or against bowel resection require a lot of experience and are subjective. The aim of this prospective, clinical study was to examine the correlation between oxygen saturation and small intestinal wall (IW) thickness, using two objective methods. In 22 colicky horses, the blood flow, oxygen saturation and relative amount of haemoglobin were measured intraoperatively via laser Doppler and white light spectroscopy (O2C, oxygen to see, LEA Medizintechnik) at six measuring points (MPs) in small and large intestines...
2017: Veterinary Record Open
https://www.readbyqxmd.com/read/28761666/radial-and-ulnar-fracture-treatment-with-paraosseous-clamp-cerclage-stabilisation-technique-in-17-toy-breed-dogs
#14
George Manchi, Mathias M Brunnberg, Muhammad Shahid, Ahmad Al Aiyan, Eric Chow, Leo Brunnberg, Silke Stein
OBJECTIVE: Description of surgical technique, complications and outcome of radius/ulna fractures in toy and miniature breed dogs treated with the paraosseous clamp-cerclage stabilisation (PCCS) method. STUDY DESIGN: Retrospective study. METHODS: Clinical records of small breed dogs with fractures of the radius and ulna were reviewed between January 2011 and January 2016. Inclusion criteria were bodyweight of ≤3.5 kg, fracture of the radius and ulna of one or two limbs without previous repair attempts, available follow-up information, and the use of PCCS for repair of the fracture as the sole method of fixation...
2017: Veterinary Record Open
https://www.readbyqxmd.com/read/28761665/efficacy-of-recombinant-bovine-epidermal-growth-factor-in-the-treatment-of-experimental-subclinical-staphylococcus-aureus-mastitis-in-a-ewe-model
#15
Kamal Gabadage, Manuel Chirino-Trejo, John Campbell, Christopher Luby
Staphylococcus aureus is the most common contagious mastitis pathogen of dairy cattle. Antimicrobial treatment of infected cattle results in variable cure rates. Epidermal growth factor (EGF) plays an important role in the modulation of host innate immune responses and the regulation of mammary epithelial regeneration, indicating that EGF may be useful as a treatment for mastitis. A pilot study was conducted to evaluate the efficacy of recombinant bovine EGF (rbEGF) for the treatment of S aureus intramammary infection (IMI) using an ovine model...
2017: Veterinary Record Open
https://www.readbyqxmd.com/read/28074144/cattle-are-a-potential-reservoir-of-bubaline-herpesvirus-1-buhv1
#16
S S Maidana, F Delgado, L Vagnoni, A Mauroy, E Thiry, S Romera
In the present work, controlled experimental infection and transmission studies in domestic cattle (Bos taurus) and water buffaloes (Bubalus bubalis) were carried out to study the in vivo behaviour of bubaline herpesvirus 1 (BuHV1). Two bovine and two buffalo calves were infected with BuHV1 (20287N isolate) by intranasal aerosolisation. Two sentinel cattle did not receive the virus challenge, but were housed with infected buffaloes to evaluate horizontal transmission. All experimentally inoculated animals showed viral infection and respiratory clinical signs...
2016: Veterinary Record Open
https://www.readbyqxmd.com/read/27933190/canine-parvovirus-cpv-2-variants-circulating-in-nigerian-dogs
#17
T T Apaa, J M Daly, R E Tarlinton
Canine parvovirus type 2 (CPV-2) is a highly contagious viral disease with three variants (CPV-2a, CPV-2b and CPV-2c) currently circulating in dogs worldwide. The main aim of this study was to determine the prevalent CPV-2 variant in faecal samples from 53 dogs presenting with acute gastroenteritis suspected to be and consistent with CPV-2 to Nigerian Veterinary Clinics in 2013-2014. Seventy-five per cent of these dogs tested positive for CPV-2 in a commercial antigen test and/or by PCR. Partial sequencing of the VP2 gene of six of these demonstrated them to be CPV-2a...
2016: Veterinary Record Open
https://www.readbyqxmd.com/read/27843559/genetic-diversity-of-bovine-viral-diarrhea-viruses-from-the-galicia-region-of-spain
#18
C Factor, E Yus, C Eiras, M L Sanjuan, M Cerviño, I Arnaiz, F J Diéguez
This study examined the frequency and diversity of bovine viral diarrhoea viruses (BVDVs) infecting cattle in Galicia (northwestern Spain). A total of 86 BVDV strains were typed in samples of serum from 79 persistently infected animals and 3 viraemic animals and of abomasal fluid from 4 fetuses. Samples came from 73 farms participating in a voluntary BVDV control programme. Typing was based on a 288-bp sequence from the 5' untranslated region amplified using primers 324 and 326. Of the 86 strains, 85 (98.8 per cent) belonged to species BVDV-1 and 1 (1...
2016: Veterinary Record Open
https://www.readbyqxmd.com/read/27843558/prevalence-of-bovine-milk-pathogens-in-azorean-pastures-mobile-versus-fixed-milking-machines
#19
C Azevedo, D Pacheco, L Soares, M Moitoso, J Maldonado, R Guix, J Simões
The aims of the present study were (1) to evaluate the influence of using mobile (n=47) or fixed (n=45) milking machines in Azorean herds on the apparent prevalence of several milk pathogens in bulk tank milk (BTM) and (2) to determine whether separated subclinical mastitic cows can serve, in real time, as predictors of milk pathogen prevalence for the remaining animals at the herd level. The use of a mobile or fixed milking machine influenced (P≤0.05) the prevalence of Staphylococcus aureus (72.3 per cent; n=34 v 51...
2016: Veterinary Record Open
https://www.readbyqxmd.com/read/27651915/streptococcus-equi-subspecies-equi-in-horses-in-israel-seroprevalence-and-strain-types
#20
S Tirosh-Levy, S E Blum, K F Steward, A S Waller, A Steinman
The purpose of this cross-sectional study was to determine the seroprevalence of Streptococcus equi in Israel, to monitor seropositive horses over time and to identify archived strains that were recovered from Israeli horses. A serological survey of 200 healthy horses on 20 farms throughout Israel was performed to detect recent exposure to S equi antigens A and C via indirect ELISA. Seroprevalence was 9.5 per cent (19/200) and positive horses were found in 30 per cent (6/20) of the farms. Sixteen horses that returned a positive serology result were retested three and six months later...
2016: Veterinary Record Open
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