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Sexual Medicine Reviews

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https://www.readbyqxmd.com/read/30342856/trazodone-in-sexual-medicine-underused-and-overdosed
#1
REVIEW
Robert E Pyke
INTRODUCTION: Treatment of hypoactive sexual desire disorder (HSDD) remains unfulfilled. The only approved medication, flibanserin (FLI), is highly underused owing to concerns about central nervous system (CNS) depression and interactions. Trazodone (TRZ), which is not often used for sexual problems, has evidence suggesting efficacy but similar concerns. AIM: To explore whether the pharmacologic similarities between TRZ and FLI could allow treatment of HSDD without CNS depression...
October 17, 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/30301708/new-developments-in-surgical-treatment-for-penile-size-preservation-in-peyronie-s-disease
#2
REVIEW
Brittani Barrett-Harlow, Jonathan Clavell-Hernandez, Run Wang
INTRODUCTION: Peyronie's disease (PD) is associated with penile length loss due to atrophy that occurs as a result of fibrous inelastic scarring. Studies have shown diminished penile length and girth, as well as the inability to participate in sexual activity, can lead to decreased quality of life, emotional challenges, and sexual dissatisfaction in a large percentage of men. AIM: To provide a summary of the new developments in the surgical techniques available for the PD patient, with a focus on procedures that provide penile size restoration...
October 6, 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/30301707/the-serendipitous-story-of-sildenafil-an-unexpected-oral-therapy-for-erectile-dysfunction
#3
REVIEW
Irwin Goldstein, Arthur L Burnett, Raymond C Rosen, Peter W Park, Vera J Stecher
INTRODUCTION: The serendipitous discovery of sildenafil (Viagra [sildenafil citrate]) as a treatment for erectile dysfunction (ED) is one of the most fascinating drug development stories of our time. When sildenafil was approved by the U.S. Food and Drug Administration in 1998, it revolutionized the treatment protocol for men with ED, once considered a psychological issue or an inevitable part of aging. AIM: To review the discovery of sildenafil and its role in changing the field of sexual medicine in the context of the epidemiology and history of treatment for ED...
October 6, 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/30301706/genital-sensations-in-persistent-genital-arousal-disorder-a-case-for-an-overarching-nosology-of-genitopelvic-dysesthesias
#4
REVIEW
Caroline F Pukall, Robyn Jackowich, Kayla Mooney, Susan M Chamberlain
INTRODUCTION: Persistent genital arousal disorder (PGAD) is a highly distressing and poorly understood condition characterized by unwanted sensations of genital arousal in the absence of subjective sexual desire. Research has shown that some individuals with PGAD also report orgasm, urinary, and pain symptoms, with 1 recent study specifically comparing a "painful persistent genital arousal symptom" group to a "non-painful persistent genital arousal symptom" group on various indicators given the highly frequent report of comorbid genitopelvic pain in their sample...
October 6, 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/30301705/the-effect-of-pelvic-floor-muscle-exercise-on-female-sexual-function-during-pregnancy-and-postpartum-a-systematic-review
#5
REVIEW
Sahar Sadat Sobhgol, Holly Priddis, Caroline A Smith, Hannah Grace Dahlen
INTRODUCTION: Pelvic floor muscle exercise (PFME) is recommended as a first-line treatment for urinary incontinence. However, a review of the literature suggests the effect of PFME on sexual function (SF), particularly during pregnancy and the postpartum period, is understudied. AIM: To assess the effect of PFME on SF during pregnancy and the postpartum period. METHODS: The following databases were searched: CINAHL (EBSCOhost), Health Collection (Informit), PubMed (National Center for Biotechnology Information), Embase (Ovid), MEDLINE, Cochrane, Health Source, Scopus, Wiley, Health & Medical Complete (ProQuest), Joanna Briggs Institute, and Google Scholar...
October 6, 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/30301704/exo-clinical-trials-of-nutritional-supplements-for-sexual-dysfunction-precedents-principles-and-protocols
#6
REVIEW
Robert E Pyke
INTRODUCTION: Care-seeking for sexual dysfunction is limited by embarrassment, efficacy/safety concerns, and cost. Nutritional supplements (NSs) are low-cost but unproven. AIM: To provide hypotheses on whether effective NS combinations for sexual dysfunction can be created following known pharmacology principles and tested with sufficient rigor in Internet-based "exo-clinical" trials (XCTs). METHODS: PubMed and Google searches were conducted to review the feasibility of XCTs of NS combinations for sexual dysfunction...
October 6, 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/30301703/sexual-problems-of-men-with-androgenic-alopecia-treated-with-5-alpha-reductase-inhibitors
#7
REVIEW
Enis Rauf Coskuner, Burak Ozkan, Mehmet Gokhan Culha
INTRODUCTION: 5-Alpha reductase inhibitors (5-ARIs) are widely used in the treatment of benign prostatic hyperplasia (BPH) and androgenic alopecia (AGA). AIM: To examine all available data on the effects of 5-ARIs on sexual functioning in AGA treatment and to assess whether 5-ARIs increase the risk of sexual dysfunction. METHODS: A literature review of publications at PubMed related to the subject was used. MAIN OUTCOME MEASURE: We assessed erectile dysfunction, ejaculation impairment, and decreased libido...
October 6, 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/30122339/masculinizing-genital-gender-confirmation-surgery
#8
REVIEW
Miriam Hadj-Moussa, Shailesh Agarwal, Dana A Ohl, William M Kuzon
INTRODUCTION: This article is the third in a 3-part series focused on the comprehensive treatment of gender dysphoria. Multidisciplinary gender dysphoria care may involve a combination of counseling, social gender transition, hormone therapy, and gender confirmation surgery (GCS) to maximize physical characteristics congruent with a patient's gender identity. Nonoperative management of gender dysphoria was covered in part 1. The focus of part 2 was feminizing GCS. In part 3, surgical considerations for masculinizing GCS are summarized, including a review of different phalloplasty techniques...
August 16, 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/30297079/tribute-to-dr-gorm-wagner-founding-father-of-issm
#9
EDITORIAL
Irwin Goldstein, Ron Lewis, Ira Sharlip
No abstract text is available yet for this article.
October 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/29891226/evaluation-and-treatment-of-gender-dysphoria-to-prepare-for-gender-confirmation-surgery
#10
REVIEW
Miriam Hadj-Moussa, Dana A Ohl, William M Kuzon
BACKGROUND: Gender dysphoria is the experience of marked distress due to incongruence between genetically determined gender and experienced gender. Treatment of gender dysphoria should be individualized and multidisciplinary, involving a combination of psychotherapy, social gender transition, cross-sex hormone therapy, gender-affirming surgery, and/or ancillary procedures and services. The goal of all treatment modalities is to alleviate distress and affirm the patient's experienced gender identity...
October 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/30098986/do-5%C3%AE-reductase-inhibitors-raise-circulating-serum-testosterone-levels-a-comprehensive-review-and-meta-analysis-to-explaining-paradoxical-results
#11
REVIEW
Abdulmaged M Traish, Yonah Krakowsky, Gheorghe Doros, Abraham Morgentaler
INTRODUCTION: Many studies have reported that 5α-reductase inhibitors (finasteride and dutasteride) raise serum testosterone (T) levels, yet there is lack of consistency among studies on this point. AIM: To review and meta-analyze available studies reporting changes in serum T concentrations in men treated with 5α-reductase inhibitors (5α-RIs). METHODS: A Medline search using PubMed and EMBASE was performed including the following key words: "finasteride," "dutasteride," "testosterone and 5α-reductases...
August 8, 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/30078620/urethral-injury-and-the-penile-prosthesis
#12
REVIEW
Evan C Carlos, Stephanie J Sexton, Aaron C Lentz
INTRODUCTION: The relative infrequency of urethral injuries during penile prosthesis implantation has caused the event to be understudied relative to the morbidity and cost associated with their management. AIM: To draw attention to both acute intraoperative and delayed urethral injuries via cylinder erosion by compiling and evaluating the available literature on their cause, diagnosis, and management. METHODS: A literature review was performed through PubMed from 1985 to 2018 regarding urethral injuries in the setting of penile prosthesis implantation...
August 2, 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/30057140/perioperative-educational-interventions-and-contemporary-sexual-function-outcomes-of-radical-prostatectomy
#13
REVIEW
Anna E R Faris, Drogo K Montague, Bradley C Gill
INTRODUCTION: Men undergoing prostatectomy can have unrealistic preoperative expectations regarding sexual function after surgery and may desire more education on recovery and symptom management. AIM: To present contemporary data on recovery of sexual function after prostatectomy and characterize how it is impacted by perioperative patient educational interventions. METHODS: A comprehensive review of the English-language literature available by PubMed search...
July 26, 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/30057139/management-strategies-in-opioid-abuse-and-sexual-dysfunction-a-review-of-opioid-induced-androgen-deficiency
#14
REVIEW
Alan Hsieh, Lorenzo DiGiorgio, Mary Fakunle, Hossein Sadeghi-Nejad
INTRODUCTION: Over the last several decades, the opioid epidemic has become a national crisis, largely spurred by the spike in the use of prescription painkillers. With the epidemic came a concomitant rise in the incidence of opioid-induced androgen deficiency (OPIAD). Although OPIAD can significantly impact male sexual function and quality of life, it is an overlooked and poorly understood clinical entity that requires more attention from healthcare providers. AIM: The objectives of the current review are to highlight the increasing incidence of OPIAD and the importance of an integrated, multidisciplinary approach to identify and treat patients with the condition...
July 26, 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/30057138/how-well-do-measurement-scales-reflect-the-actual-experience-of-sexuality-in-mid-life-and-beyond
#15
Ashley Macleod, Marita P McCabe
BACKGROUND: There is limited evidence that current sexuality measures accurately reflect the experience of sexuality among older people. AIM: This review investigates whether sexuality scales that examine aspects of sexuality for heterosexual men and women in mid-life and beyond accurately reflect the experiences of these individuals as discussed within qualitative studies. METHODS: Online databases and reference lists were searched for articles from 1997 that investigated experiences of sexuality, aging, and validated sexuality scales...
July 26, 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/30057137/the-impact-of-thyroid-disease-on-sexual-dysfunction-in-men-and-women
#16
REVIEW
Andrew T Gabrielson, Rita A Sartor, Wayne J G Hellstrom
BACKGROUND: Individually, thyroid disease and sexual dysfunction are common conditions that can have a detrimental effect on quality of life. Recent reports have documented an increased prevalence of sexual dysfunction among patients with thyroid disorders. As such, it is important for sexual medicine physicians to be primed on the presentation of patients with overlying sexual and thyroid dysfunction to allow for proper management. AIM: To review the available literature exploring the relationship between thyroid disease and sexual dysfunction in men and women...
July 26, 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/30057136/novel-treatment-for-premature-ejaculation-in-the-light-of-currently-used-therapies-a-review
#17
REVIEW
Hartmut Porst, Andrea Burri
INTRODUCTION: Besides erectile dysfunction, premature ejaculation (PE) is the most frequent male sexual disorder and shows a high level of bother and distress. The negative consequences of long-term and unsuccessfully treated PE on both patient and partner are well established in the literature and include personal distress, impairment of the partner's sexual function, and interpersonal difficulties. AIM: To outline the consequences of untreated PE and the advantages and disadvantages of currently available treatment options with a special focus on a new topical eutectic lidocaine/prilocaine metered dose spray (Fortacin; Lidocaine/Prilocaine, Recordati, Milan, Italy) which represents the second officially approved drug in this indication...
July 26, 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/30033128/penile-prosthesis-complications-planning-prevention-and-decision-making
#18
REVIEW
Nickolas D Scherzer, Brian Dick, Andrew T Gabrielson, Laith M Alzweri, Wayne J G Hellstrom
INTRODUCTION: Inflatable penile prosthesis (IPP) is an established treatment option for men with erectile dysfunction (ED) refractory to medical therapy. Standardization of surgical technique and improvements in device construction have reduced all-cause complication rates to less than 5% in recent reports. Nonetheless, complications do exist, and can strongly impact morbidity and the quality of life of patients. Prosthetic urologists must be aware of the constellation of complications that can arise during or after IPP placement...
July 19, 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/29914753/treatments-for-hypoactive-sexual-desire-disorder-hsdd-and-the-pursuit-of-sexual-health-for-women-amidst-inglorious-rhetoric
#19
EDITORIAL
Noel N Kim, Irwin Goldstein, Lisa Larkin, Susan Kellogg-Spadt, James A Simon
No abstract text is available yet for this article.
July 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/29606552/sexual-activity-recommendations-in-high-risk-pregnancies-what-is-the-evidence
#20
REVIEW
Sally E MacPhedran
BACKGROUND: While sexual activity in normal, healthy pregnant women is safe, concern regarding elements of the sexual act have led to restrictions in pregnancies experiencing complications that are frequently insufficiently addressed in clinical practice. AIM: To comprehensively review the literature for evidence that supports or refutes specific sexual activity restrictions in high-risk pregnancy conditions. METHODS: A search of PubMed, MEDLINE, Ovid, UpToDate, Google Scholar, and Google for relevant publications related to any aspect of sexual activity affecting high-risk pregnancies complicated by history of pre-term delivery, shortened cervix, presence of cerclage, pre-mature rupture of membranes, placenta abruption, placenta previa, multiple gestation, or history of classical cesarean section was performed...
July 2018: Sexual Medicine Reviews
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