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Sexual Medicine Reviews

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https://www.readbyqxmd.com/read/29960874/cardiovascular-safety-of-phosphodiesterase-type-5-inhibitors-after-nearly-2-decades-on-the-market
#1
REVIEW
Robert A Kloner, Irwin Goldstein, Michael G Kirby, John D Parker, Richard Sadovsky
BACKGROUND: The phosphodiesterase-5 (PDE5) inhibitors that have been available for nearly 20 years are highly effective in treating erectile dysfunction and have been consistently shown to be safe when used according to package insert instructions. AIM: To review the cardiovascular (CV) safety of PDE5 inhibitors used to treat erectile dysfunction. METHODS: PubMed, the Derwent Drug File, and Embase were searched to identify papers published from 1990-2016 presenting CV safety data for PDE5 inhibitors...
June 27, 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/29960873/the-use-of-stromal-vascular-fraction-in-the-treatment-of-male-sexual-dysfunction-a-review-of-preclinical-and-clinical-studies
#2
REVIEW
Nora M Haney, Andrew Gabrielson, Taylor P Kohn, Wayne J G Hellstrom
INTRODUCTION: Stem cell therapy using stromal vascular fraction (SVF) is a promising treatment modality. SVF is comprised of a mixture of adipose-derived stem cells, endothelial precursor cells, and immune modulatory cells that act synergistically to facilitate angiogenesis and epithelial cell differentiation. This makes SVF an attractive option for men's sexual disorders that require reconstitution of vasculature and endothelial lining, namely erectile dysfunction (ED) and Peyronie's disease (PD)...
June 27, 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/29914753/treatments-for-hypoactive-sexual-desire-disorder-hsdd-and-the-pursuit-of-sexual-health-for-women-amidst-inglorious-rhetoric
#3
EDITORIAL
Noel N Kim, Irwin Goldstein, Lisa Larkin, Susan Kellogg-Spadt, James A Simon
No abstract text is available yet for this article.
June 15, 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/29891226/evaluation-and-treatment-of-gender-dysphoria-to-prepare-for-gender-confirmation-surgery
#4
REVIEW
Miriam Hadj-Moussa, Dana A Ohl, William M Kuzon
BACKGROUND: Gender dysphoria is the experience of marked distress due to incongruence between genetically determined gender and experienced gender. Treatment of gender dysphoria should be individualized and multidisciplinary, involving a combination of psychotherapy, social gender transition, cross-sex hormone therapy, gender-affirming surgery, and/or ancillary procedures and services. The goal of all treatment modalities is to alleviate distress and affirm the patient's experienced gender identity...
June 8, 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/29730315/cardiometabolic-risk-and-female-sexuality-part-i-risk-factors-and-potential-pathophysiological-underpinnings-for-female-vasculogenic-sexual-dysfunction-syndromes
#5
REVIEW
Elisa Maseroli, Irene Scavello, Linda Vignozzi
INTRODUCTION: Erectile dysfunction is recognized as an opportunity for preventing cardiovascular (CV) events, and assessing the impairment of penile vascular flow by Doppler ultrasound is an important tool to ascertain CV risk. Conversely, the role of genital vascular impairment in the pathophysiology of female sexual dysfunction (FSD) remains contentious. AIM: To focus on the current scientific support for an association between CV risk factors and female sexual health in the 1st part of a 2-part review...
May 2, 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/29730314/comparison-of-infrapubic-vs-penoscrotal-approaches-for-3-piece-inflatable-penile-prosthesis-placement-do-we-have-a-winner
#6
REVIEW
Franco Palmisano, Luca Boeri, Cristiano Cristini, Gabriele Antonini, Matteo Giulio Spinelli, Giorgio Franco, Fabrizio Longo, Franco Gadda, Fulvio Colombo, Emanuele Montanari
BACKGROUND: The 3-piece inflatable penile prosthesis (IPP) is the gold standard treatment for male erectile dysfunction when other less invasive approaches are contra-indicated or unacceptable for the patient. There are currently 2 surgical approaches for IPP implantation: the penoscrotal (PS) and the infrapubic (IP) incision. AIM: To assess the most recent evidence on the impact of surgical approach for 3-piece IPP implantation in patients with erectile dysfunction...
May 2, 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/29680294/klinefelter-syndrome-the-effects-of-early-androgen-therapy-on-competence-and-behavioral-phenotype
#7
REVIEW
Ryan Flannigan, Premal Patel, Darius A Paduch
INTRODUCTION: Klinefelter syndrome (KS) is the result of sex chromosome aneuploidy most often characterized as 47,XXY. The typical features of KS include tall stature, gynecomastia, small firm testicles, hypergonadotropic hypogonadism, and infertility. However, abnormalities in neurodevelopment, cognition, and social and behavioral functioning also can be present. The abnormalities in neurodevelopment are believed to be due in part to androgen deficiency during early development and puberty...
April 18, 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/29678474/the-impact-of-body-awareness-on-women-s-sexual-health-a-comprehensive-review
#8
REVIEW
Brooke N Seal, Cindy M Meston
INTRODUCTION: Body awareness has been linked to female sexual response in laboratory manipulation studies and is used in clinical settings to ameliorate sexual difficulties. AIM: To evaluate and review the literature on body awareness and female sexual function. METHODS: A literature review was conducted through PsycInfo, PsycARTICLES, and PubMed using terms such as body awareness and sexual function. A manual search also was conducted using reference lists...
April 17, 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/29678473/female-sexual-dysfunction-among-muslim-women-increasing-awareness-to-improve-overall-evaluation-and-treatment
#9
REVIEW
Sameena Rahman
INTRODUCTION: Muslim women are an increasingly underserved population in the United States and worldwide. Diagnosis and treatment of female sexual dysfunction bring unique challenges because of the conservative nature of those practicing the religion. Several cultural and religious codes of conduct affect sexual behavior and the dysfunction that can ensue. AIM: To assess and describe the types of sexual dysfunction that have been found in Muslim women internationally and encourage a better understanding of their issues to enhance health care delivery...
April 17, 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/29661690/the-history-of-testosterone-and-the-evolution-of-its-therapeutic-potential
#10
REVIEW
Abraham Morgentaler, Abdulmaged Traish
INTRODUCTION: Testosterone therapy has been controversial since its synthesis in the 1930s to the present day. Testosterone's history provides depth and context for current controversies. AIM: To review the history of testosterone therapy from its initial synthesis in the 1930s to the modern day. METHODS: Expert review of the literature. MAIN OUTCOME MEASURES: Impactful events in the history of testosterone. RESULTS: By the 1940s there was already a fascinating literature that described the many symptomatic benefits of testosterone therapy that are recognized today...
April 13, 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/29661689/cardiometabolic-risk-and-female-sexuality-part-ii-understanding-and-overcoming-gender-differences-the-key-role-of-an-adequate-methodological-approach
#11
REVIEW
Elisa Maseroli, Irene Scavello, Linda Vignozzi
INTRODUCTION: Although basic science and clinical research indicate that the vascular physiopathology of male and female sexual dysfunction (FSD) is similar, to date the association between FSD and cardiovascular (CV) diseases has been only marginally explored. AIM: To discuss the potential reasons for differences in the role of CV diseases and risk factors in sexual function in women vs men in the 2nd part of a 2-part review. METHODS: A thorough literature search of peer-reviewed publications on the topic was performed using the PubMed database...
April 13, 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/29631981/role-of-androgens-in-female-genitourinary-tissue-structure-and-function-implications-in-the-genitourinary-syndrome-of-menopause
#12
REVIEW
Abdulmaged M Traish, Linda Vignozzi, James A Simon, Irwin Goldstein, Noel N Kim
INTRODUCTION: Genitourinary conditions in women increase in prevalence with age. Androgens are prerequisite hormones of estrogen biosynthesis, are produced in larger amounts than estrogens in women, and decrease throughout adulthood. However, research and treatment for genitourinary complaints have traditionally focused on estrogens to the exclusion of other potential hormonal influences. AIM: To summarize and evaluate the evidence that androgens are important for maintaining genitourinary health in women and that lack of androgenic activity can contribute to the development of symptoms of the genitourinary syndrome of menopause...
April 6, 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/29631980/stem-cell-therapy-for-erectile-dysfunction
#13
REVIEW
Ethan L Matz, Ryan Terlecki, Yuanyuan Zhang, John Jackson, Anthony Atala
INTRODUCTION: The prevalence of erectile dysfunction (ED) is substantial and continues to rise. Current therapeutics for ED consist of oral medications, intracavernosal injections, vacuum erection devices, and penile implants. While such options may manage the disease state, none of these modalities, however, restore function. Stem cell therapy has been evaluated for erectile restoration in animal models. These cells have been derived from multiple tissues, have varied potential, and may function via local engraftment or paracrine signaling...
April 6, 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/29631979/penile-traction-therapy-and-vacuum-erection-devices-in-peyronie-s-disease
#14
REVIEW
Ross A Avant, Matthew Ziegelmann, Avinash Nehra, Manaf Alom, Tobias Kohler, Landon Trost
INTRODUCTION: Peyronie's disease (PD) has historically been managed by at least 1 treatment, including oral supplements or medications, intralesional injections, or surgery. Adjunctive mechanical therapies also have been described, including penile traction therapy (PTT) and vacuum erection devices (VEDs), although relatively limited data are available on their use with PD. AIM: To review and summarize the published literature on the role and efficacy of PTT and VED in men with PD...
April 6, 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/29631978/suppression-of-cavernosal-fibrosis-in-a-rat-model
#15
REVIEW
Min Chul Cho, Won Hoon Song, Jae-Seung Paick
INTRODUCTION: Cavernosal fibrosis is an important pathologic condition leading to erectile dysfunction (ED). The etiologies of cavernosal fibrosis include aging, diabetes mellitus, castration, cavernosal nerve injury during radical prostatectomy, hypertension, and Peyronie disease. AIMS: To summarize published studies investigating suppression of cavernosal fibrosis in rat models of ED of various etiologies. METHODS: A literature search was conducted using PubMed...
April 6, 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/29605061/response-and-rebuttal-to-existential-issues-in-sexual-medicine-the-relation-between-death-anxiety-and-hypersexuality
#16
LETTER
Daniel N Watter
No abstract text is available yet for this article.
April 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/29605060/response-regarding-existential-issues-in-sexual-medicine-the-relation-between-death-anxiety-and-hypersexuality
#17
LETTER
Giacomo Ciocca, Erika Limoncin, Vittorio Lingiardi, Andrea Burri, Emmanuele A Jannini
No abstract text is available yet for this article.
April 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/29605059/four-decades-of-change-in-sexual-medicine
#18
EDITORIAL
Irwin Goldstein
No abstract text is available yet for this article.
April 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/29463440/post-ssri-sexual-dysfunction-preclinical-to-clinical-is-it-fact-or-fiction
#19
REVIEW
Enis Rauf Coskuner, Mehmet Gokhan Culha, Burak Ozkan, Elcin Orhan Kaleagasi
INTRODUCTION: Selective serotonin reuptake inhibitors (SSRIs) are a widely used class of drug for various psychiatric disorders during the lifespan, including pregnancy, lactation, childhood, and adolescence. Deterioration in sexual functioning is a major and serious adverse effect of SSRIs. There is emerging evidence that SSRIs can have long-lasting effects on sexuality. AIM: To summarize the long-lasting effects of SSRIs on sexuality, starting with animal models and continuing with the clinical experience of different investigators...
April 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/29371142/methodologic-considerations-for-the-study-of-childhood-sexual-abuse-in-sexual-health-outcome-research-a-comprehensive-review
#20
REVIEW
Chelsea D Kilimnik, Carey S Pulverman, Cindy M Meston
INTRODUCTION: Childhood sexual abuse (CSA) has been a topic of interest in sexual health research for decades, yet literature on the sexual health correlates of CSA has been hindered by methodologic inconsistencies that have resulted in discrepant samples and mixed results. AIM: To review the major methodologic inconsistencies in the field, explore the scientific and clinical impact of these inconsistencies, and propose methodologic approaches to increase consistency and generalizability to the general population of women with CSA histories...
April 2018: Sexual Medicine Reviews
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